Giracodazole
AlkaPlorer ID: AK021425
Synonym: None
IUPAC Name: (1S,2S)-3-amino-1-(2-amino-1H-imidazol-5-yl)-2-chloropropan-1-ol
Structure
SMILES: N=C1NC=C([C@H](O)[C@@H](Cl)CN)N1
InChI: InChI=1S/C6H11ClN4O/c7-3(1-8)5(12)4-2-10-6(9)11-4/h2-3,5,12H,1,8H2,(H3,9,10,11)/t3-,5+/m0/s1
InChIKey: YILCGOCHVFQMTC-WVZVXSGGSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Cymbastela cantharella | Cymbastela | Axinellidae | Axinellida | Demospongiae | Porifera | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 190.634
TPSA？: 101.68
MolLogP？: -0.5782300000000002
Number of H-Donors: 5
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 77.0 | nM | 10.1016/j.bmc.2009.02.050 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 77.0 | nM | 10.1016/j.bmc.2021.116058 |