Molecule

erythro-5-hydroxy-L-lysinium(1+)

AlkaPlorer ID: AK021564

Synonym: '18899-31-5', '18899-30-4', 'erythro-5-hydroxy-L-lysinium cation', '5-Hydroxy-L-lysine', '5-hydroxy-L-lysine', '78088-29-6', '5-Hydroxylysine', '(5R)-5-hydroxy-L-lysine', '(2S,5R)-2,6-diazaniumyl-5-hydroxyhexanoate', '1190-94-9', '6000-08-4', 'erythro-5-hydroxy-L-lysinium'

IUPAC Name: (2S,5R)-2,6-diamino-5-hydroxyhexanoic acid

Structure

SMILES: NC[C@H](O)CC[C@H](N)C(=O)O

InChI: InChI=1S/C6H14N2O3/c7-3-4(9)1-2-5(8)6(10)11/h4-5,9H,1-3,7-8H2,(H,10,11)/t4-,5+/m1/s1

InChIKey: YSMODUONRAFBET-UHNVWZDZSA-N

Reference

Hydroxylysine from alfalfa roots

PubChem CID: 3032849

LOTUS: LTS0237970

SuperNatural Ⅲ: SN0459089-02

NPASS: NPC68974

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Agaricus campestris	Agaricus	Agaricaceae	Agaricales	Agaricomycetes	Basidiomycota	Fungi	Eukaryota
Homo sapiens	Homo	Hominidae	Primates	Mammalia	Chordata	Metazoa	Eukaryota

Properties Information

Molecule Weight: 162.18900000000002

TPSA？: 109.57

MolLogP？: -1.5018999999999991

Number of H-Donors: 4

Number of H-Acceptors: 4

RingCount: 0

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Glycine max	Glutamine synthetase	Inhibition	21.0	%	10.1016/j.bmc.2008.04.015
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	Glutamine synthetase	Ki	40000.0	nM	10.1016/j.bmc.2008.04.015
None	Unchecked	IC50	610000.0	nM	10.1016/j.bmc.2008.04.015
None	Unchecked	Inhibition	22.0	%	10.1016/j.bmc.2008.04.015
None	Unchecked	Inhibition	56.0	%	10.1016/j.bmc.2008.04.015
None	Unchecked	Inhibition	58.0	%	10.1016/j.bmc.2008.04.015

Metabolism Information

AKRT ID	Reaction	Reaction Link ID
AKRT016483	N=c1[nH]c(=O)c2ncn([C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2[nH]1.NC[C@H](O)CC[C@H](N)C(=O)O>>N=c1[nH]c(=O)c2ncn([C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2[nH]1.NC[C@@H](CC[C@H](N)C(=O)O)OP(=O)(O)O	None
AKRT018468	NC[C@H](O)CC[C@H](N)C(=O)O.Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1>>NC[C@@H](CC[C@H](N)C(=O)O)OP(=O)(O)O.Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1	None
AKRT018469	NC[C@H](O)CC[C@H](N)C(=O)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O>>NC[C@@H](CC[C@H](N)C(=O)O)OP(=O)(O)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O	None
AKRT018470	NC[C@H](O)CC[C@H](N)C(=O)O>>NCCC[C@@H](O)CN	enzymemap_81557
AKRT018471	NC[C@H](O)CC[C@H](N)C(=O)O>>NC[C@@H](CC[C@H](N)C(=O)O)OP(=O)(O)O	R03378
AKRT018472	NC[C@H](O)CC[C@H](N)C(=O)O>>O=C=O	enzymemap_81557