Clausine L
AlkaPlorer ID: AK021758
Synonym: None
IUPAC Name: methyl 2-methoxy-9H-carbazole-3-carboxylate
Structure
SMILES: COC(=O)C1=CC2=C(C=C1OC)NC1=CC=CC=C12
InChI: InChI=1S/C15H13NO3/c1-18-14-8-13-10(7-11(14)15(17)19-2)9-5-3-4-6-12(9)16-13/h3-8,16H,1-2H3
InChIKey: BYDOYRHWHKPKQP-UHFFFAOYSA-N
Reference
Chemical and antiplatelet aggregative investigation of the leaves of Clausena excavata
PubChem CID: 24898872
CAS: 14501-65-6
LOTUS: LTS0093762
COCONUT: CNP0293814
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Clausena excavata | Clausena | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 255.273
TPSA？: 51.32
MolLogP？: 3.1163000000000016
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Chlorocebus sabaeus | Vero | IC50 | nan | None | 10.1016/j.bmc.2016.12.038 |
| Escherichia coli | Escherichia coli | MIC | 128.0 | ug.mL-1 | 10.1021/np3000365 |
| Homo sapiens | KB | IC50 | nan | None | 10.1021/np3000365 |
| Homo sapiens | MCF7 | IC50 | nan | None | 10.1021/np3000365 |
| Homo sapiens | NCI-H187 | IC50 | nan | None | 10.1021/np3000365 |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC90 | 50000.0 | nM | 10.1016/j.bmc.2016.12.038 |
| Salmonella enterica subsp. enterica serovar Typhimurium | Salmonella typhimurium | MIC | 128.0 | ug.mL-1 | 10.1021/np3000365 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | nan | None | 10.1021/np3000365 |