Polyoxin N
AlkaPlorer ID: AK021895
Synonym: None
IUPAC Name: (2S)-2-[[(2S,3S,4S)-2-amino-5-carbamoyloxy-3,4-dihydroxypentanoyl]amino]-2-[(2R,3S,4R,5R)-5-(5-formyl-2-oxo-1H-imidazol-3-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid
Structure
SMILES: N=C(O)OC[C@H](O)[C@@H](O)[C@H](N)C(O)=N[C@H](C(=O)O)[C@H]1O[C@@H](N2C=C(C=O)N=C2O)[C@H](O)[C@@H]1O
InChI: InChI=1S/C16H23N5O12/c17-6(8(24)5(23)3-32-15(18)30)12(27)20-7(14(28)29)11-9(25)10(26)13(33-11)21-1-4(2-22)19-16(21)31/h1-2,5-11,13,23-26H,3,17H2,(H2,18,30)(H,19,31)(H,20,27)(H,28,29)/t5-,6-,7-,8+,9-,10+,11+,13+/m0/s1
InChIKey: OSWKWKBETDCHCA-OHRMCWGFSA-N
Reference
Polyoxin N, a New Member of the Polyoxin Family
PubChem CID: 102269641
LOTUS: LTS0185258
{NPAtlas: NPA014222
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces piomogenus | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 477.38300000000015
TPSA？: 294.48999999999995
MolLogP？: -4.011429999999995
Number of H-Donors: 10
Number of H-Acceptors: 14
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Candida albicans | Candida albicans | MIC | 6.0 | ug.mL-1 | 10.1021/acs.jmedchem.6b00325 |