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name Structure Reference Source Properties Activities Metabolism

amoxicillin

AlkaPlorer ID: AK022321

Synonym: 'MLS002222248', 'MLS000028632', 'Amoxicillin', 'AMOXICILLIN CRYSTALLINE', 'SMR000058707'

IUPAC Name: (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Structure

SMILES: CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)C3=CC=C(O)C=C3)C(=O)N2[C@H]1C(=O)O

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InChI: InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1

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InChIKey: LSQZJLSUYDQPKJ-NJBDSQKTSA-N

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Properties Information

Molecule Weight: 365.4110000000001

TPSA？: 132.96

MolLogP？: 0.0237000000000004

Number of H-Donors: 4

Number of H-Acceptors: 6

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter Acinetobacter MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Acinetobacter baumannii Acinetobacter baumannii Inhibition 22.8 % 10.6019/CHEMBL4513141
Acinetobacter baumannii Acinetobacter baumannii MBC 100.0 mg/L 10.1007/s00044-011-9933-5
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00856-09
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01164-08
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.00050-10
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.00050-10
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.00393-08
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.00856-09
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.01164-08
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.00050-10
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.00267-07
Acinetobacter baumannii Acinetobacter baumannii MIC 128.0 ug.mL-1 10.1128/aac.00050-10
Acinetobacter baumannii Acinetobacter baumannii MIC 128.0 ug.mL-1 10.1128/aac.00267-07
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00050-10
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00267-07
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00393-08
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00856-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00861-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.01164-08
Acinetobacter baumannii Acinetobacter baumannii MIC 175000.0 nM 10.1021/acs.jmedchem.1c01482
Acinetobacter calcoaceticus subsp. anitratus Acinetobacter calcoaceticus subsp. anitratus MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Acinetobacter haemolyticus Acinetobacter haemolyticus MIC 256.0 ug.mL-1 10.1128/aac.00267-07
Acinetobacter radioresistens Acinetobacter radioresistens MIC 2.0 ug.mL-1 10.1128/aac.00999-08
Acinetobacter radioresistens Acinetobacter radioresistens MIC 32.0 ug.mL-1 10.1128/aac.00999-08
Aeromonas Aeromonas MIC90 32.0 ug.mL-1 10.1021/jm00021a013
Aeromonas caviae IMP-19 Kcat 456.0 /s 10.1128/aac.01462-06
Aeromonas caviae IMP-19 Kcat/Km 2.2 None 10.1128/aac.01462-06
Aeromonas caviae IMP-19 Km 207000.0 nM 10.1128/aac.01462-06
Aeromonas sp. Aeromonas sp. MIC 8.0 ug.mL-1 10.1128/aac.00770-08
Aeromonas sp. Aeromonas sp. MIC 256.0 ug.mL-1 10.1128/aac.00770-08
Aeromonas sp. Aeromonas sp. MIC90 32.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Anaerococcus prevotii Anaerococcus prevotii MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Anaerococcus tetradius Anaerococcus tetradius MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Anaerococcus tetradius Anaerococcus tetradius MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Anaerococcus tetradius Anaerococcus tetradius MIC90 0.125 ug.mL-1 10.1128/aac.01557-08
Aspergillus flavus Aspergillus flavus MIC 2.0 ug.mL-1 10.1007/s00044-011-9755-5
Aspergillus fumigatus Aspergillus fumigatus IZ 25.0 mm 10.1016/j.ejmech.2009.09.002
Aspergillus fumigatus Aspergillus fumigatus IZ 25.0 mm 10.1016/j.ejmech.2019.111744
Aspergillus fumigatus Aspergillus fumigatus MIC 15.6 ug.mL-1 10.1039/d2md00076h
Aspergillus fumigatus Aspergillus fumigatus MIC50 100.0 ug.mL-1 10.1016/j.bmcl.2007.08.021
Aspergillus fumigatus Aspergillus fumigatus Ratio 1.0 None 10.1016/j.ejmech.2009.09.002
Aspergillus niger Aspergillus niger IZ 0.0 mm 10.1007/s00044-011-9857-0
Aspergillus niger Aspergillus niger IZ 21.0 mm 10.1016/j.ejmech.2019.111744
Aspergillus niger Aspergillus niger MIC 2.0 ug.mL-1 10.1007/s00044-011-9755-5
Bacillus cereus Bacillus cereus IZ 20.0 mm 10.1016/j.ejmech.2020.113034
Bacillus cereus Bacillus cereus IZ 21.0 mm 10.1016/j.ejmech.2019.111744
Bacillus cereus Bacillus cereus MIC 11000.0 nM 10.1021/acs.jnatprod.5b00206
Bacillus cereus Bacillus cereus MIC 44000.0 nM 10.1021/acs.jnatprod.5b00206
Bacillus clausii Beta-lactamase Activity 50.0 None 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat 85.0 /s 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat/Km 4.0 /uM/s 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Km 22000.0 nM 10.1128/aac.00537-07
Bacillus pumilus Bacillus pumilus IZ 10.0 mm 10.1007/s00044-012-0011-4
Bacillus pumilus Bacillus pumilus MIC 0.5 ug.mL-1 10.1007/s00044-012-0011-4
Bacillus pumilus Bacillus pumilus MIC 500.0 ug.mL-1 10.1007/s00044-012-0202-z
Bacillus spizizenii Bacillus spizizenii IZ 14.0 mm 10.1016/j.ejmech.2017.05.010
Bacillus spizizenii Bacillus spizizenii MIC 1.5 ug.mL-1 10.1016/j.ejmech.2017.05.010
Bacillus spizizenii Bacillus spizizenii MIC 200.0 nM 10.1021/acs.jnatprod.5b00206
Bacillus subtilis Bacillus subtilis EC50 150.0 nM 10.1016/j.ejmech.2022.114502
Bacillus subtilis Bacillus subtilis IZ 10.5 mm 10.1016/j.ejmech.2010.08.005
Bacillus subtilis Bacillus subtilis IZ 12.0 mm 10.1016/j.ejmech.2010.03.028
Bacillus subtilis Bacillus subtilis IZ 12.0 mm 10.1016/j.ejmech.2020.112832
Bacillus subtilis Bacillus subtilis IZ 12.0 mm 10.1016/j.ejmech.2020.113034
Bacillus subtilis Bacillus subtilis IZ 14.5 mm 10.1016/j.ejmech.2010.08.005
Bacillus subtilis Bacillus subtilis IZ 15.5 mm 10.1016/j.bmc.2019.02.044
Bacillus subtilis Bacillus subtilis IZ 15.5 mm 10.1039/d2md00076h
Bacillus subtilis Bacillus subtilis IZ 16.0 mm 10.1007/s00044-010-9440-0
Bacillus subtilis Bacillus subtilis IZ 16.3 mm 10.1007/s00044-012-0084-0
Bacillus subtilis Bacillus subtilis IZ 19.0 mm 10.1007/s00044-012-0084-0
Bacillus subtilis Bacillus subtilis IZ 20.0 mm 10.1007/s00044-012-0032-z
Bacillus subtilis Bacillus subtilis IZ 20.0 mm 10.1016/j.ejmech.2008.09.029
Bacillus subtilis Bacillus subtilis IZ 21.2 mm 10.1016/j.ejmech.2014.03.037
Bacillus subtilis Bacillus subtilis IZ 24.0 mm 10.1016/j.ejmech.2009.09.002
Bacillus subtilis Bacillus subtilis IZ 25.0 mm 10.1007/s00044-011-9634-0
Bacillus subtilis Bacillus subtilis IZ 25.0 mm 10.1016/j.ejmech.2009.02.020
Bacillus subtilis Bacillus subtilis IZ 25.0 mm 10.1016/j.ejmech.2019.111744
Bacillus subtilis Bacillus subtilis IZ 29.0 mm 10.1007/s00044-010-9440-0
Bacillus subtilis Bacillus subtilis IZ 34.0 mm 10.1007/s00044-009-9184-x
Bacillus subtilis Bacillus subtilis IZ 34.89 mm 10.1007/s00044-007-9017-8
Bacillus subtilis Bacillus subtilis MIC 0.03 ug.mL-1 10.1016/j.bmcl.2015.06.010
Bacillus subtilis Bacillus subtilis MIC 0.2 ug.mL-1 10.1007/s00044-011-9733-y
Bacillus subtilis Bacillus subtilis MIC 0.32 ug.mL-1 10.1016/j.ejmech.2022.114502
Bacillus subtilis Bacillus subtilis MIC 0.39 ug.mL-1 10.1016/j.ejmech.2015.03.021
Bacillus subtilis Bacillus subtilis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2012.08.084
Bacillus subtilis Bacillus subtilis MIC 0.5 ug.mL-1 10.1016/j.ejmech.2011.02.066
Bacillus subtilis Bacillus subtilis MIC 1.0 ug.mL-1 10.1021/acs.jnatprod.5b00008
Bacillus subtilis Bacillus subtilis MIC 1.56 ug.mL-1 10.1016/j.ejmech.2007.01.022
Bacillus subtilis Bacillus subtilis MIC 3.0 ug.mL-1 10.1007/s00044-011-9755-5
Bacillus subtilis Bacillus subtilis MIC 6.25 ug.mL-1 10.1007/s00044-011-9634-0
Bacillus subtilis Bacillus subtilis MIC 12.5 ug.mL-1 10.1016/j.bmcl.2007.09.062
Bacillus subtilis Bacillus subtilis MIC 16.0 ug.mL-1 10.1016/j.bmcl.2012.09.083
Bacillus subtilis Bacillus subtilis MIC 64.0 ug.mL-1 10.1016/j.ejmech.2010.03.028
Bacillus subtilis Bacillus subtilis MIC 64.0 ug.mL-1 10.1016/j.ejmech.2011.04.034
Bacillus subtilis Bacillus subtilis MIC50 3.2 ug.mL-1 10.1007/s00044-011-9634-0
Bacillus subtilis Bacillus subtilis Ratio 1.0 None 10.1016/j.ejmech.2009.09.002
Bacillus thuringiensis Bacillus thuringiensis MIC 6.0 ug.mL-1 10.1007/s00044-011-9755-5
Bacteroides caccae Bacteroides caccae Activity 20.0 % 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae Activity 30.0 % 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae Activity 53.0 % 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC 0.125 ug.mL-1 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae MIC 2.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae MIC50 8.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae MIC90 32.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis Activity 6.2 % 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis Activity 23.0 % 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis Activity 63.0 % 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis Km 22.0 ug ml-1 10.1016/j.bmcl.2004.02.068
Bacteroides fragilis Bacteroides fragilis Km 27.3 ug ml-1 10.1016/j.bmcl.2004.02.068
Bacteroides fragilis Bacteroides fragilis MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis MIC 0.25 ug.mL-1 10.1128/aac.01557-08
Bacteroides fragilis Bacteroides fragilis MIC 0.5 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis MIC 2.1 ug.mL-1 10.1016/s0960-894x(98)00206-6
Bacteroides fragilis Bacteroides fragilis MIC 2.1 ug.mL-1 10.1021/jm000169n
Bacteroides fragilis Bacteroides fragilis MIC 2.1 ug.mL-1 10.1021/jm9900671
Bacteroides fragilis Bacteroides fragilis MIC50 0.5 ug.mL-1 10.1128/aac.01557-08
Bacteroides fragilis Bacteroides fragilis MIC50 1.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis MIC50 4.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis MIC90 2.0 ug.mL-1 10.1128/aac.01557-08
Bacteroides fragilis Bacteroides fragilis MIC90 8.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis MIC90 32.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Bacteroides fragilis Bacteroides fragilis MIC90 32.0 ug.mL-1 10.1021/jm00021a013
Bacteroides fragilis Bacteroides fragilis MIC90 32.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis Ratio 0.0521 None 10.1016/j.bmcl.2004.02.068
Bacteroides fragilis Bacteroides fragilis Ratio 11.1 None 10.1016/j.bmcl.2004.02.068
Bacteroides fragilis Bacteroides fragilis Vmax 0.0175 None 10.1016/j.bmcl.2004.02.068
Bacteroides fragilis Bacteroides fragilis Vmax 2.94 None 10.1016/j.bmcl.2004.02.068
Bacteroides ovatus Bacteroides ovatus Activity 17.1 % 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus MIC 0.125 ug.mL-1 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus MIC 0.5 ug.mL-1 10.1128/aac.01557-08
Bacteroides ovatus Bacteroides ovatus MIC50 0.5 ug.mL-1 10.1128/aac.01557-08
Bacteroides ovatus Bacteroides ovatus MIC50 1.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus MIC90 2.0 ug.mL-1 10.1128/aac.01557-08
Bacteroides ovatus Bacteroides ovatus MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. Activity 19.6 % 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. MIC 0.25 ug.mL-1 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris Activity 19.6 % 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC 0.25 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC 0.5 ug.mL-1 10.1128/aac.01557-08
Bacteroides stercoris Bacteroides stercoris MIC50 1.0 ug.mL-1 10.1128/aac.01557-08
Bacteroides stercoris Bacteroides stercoris MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 4.9 % 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 33.0 % 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 63.0 % 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 0.125 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 0.5 ug.mL-1 10.1128/aac.01557-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 4.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 1.0 ug.mL-1 10.1128/aac.01557-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 4.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 4.0 ug.mL-1 10.1128/aac.01557-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 32.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis Activity 12.3 % 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis Activity 30.0 % 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis Activity 53.0 % 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC 0.25 ug.mL-1 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis MIC 0.5 ug.mL-1 10.1128/aac.01557-08
Bacteroides uniformis Bacteroides uniformis MIC 2.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC50 0.5 ug.mL-1 10.1128/aac.01557-08
Bacteroides uniformis Bacteroides uniformis MIC50 1.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis MIC50 8.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis MIC90 32.0 ug.mL-1 10.1128/aac.00355-08
Bifidobacterium longum Bifidobacterium longum MIC 1.5 ug.mL-1 10.1016/j.ejmech.2017.05.010
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Burkholderia cenocepacia Burkholderia cenocepacia MIC 512.0 ug.mL-1 10.1128/aac.00946-08
Campylobacter coli Campylobacter coli MIC 8.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC 64.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC50 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC90 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 0.25 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 0.5 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 1.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 2.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 2.2 ug.mL-1 10.1016/s0960-894x(98)00206-6
Campylobacter jejuni Campylobacter jejuni MIC 2.2 ug.mL-1 10.1021/jm000169n
Campylobacter jejuni Campylobacter jejuni MIC 2.2 ug.mL-1 10.1021/jm9900671
Campylobacter jejuni Campylobacter jejuni MIC 4.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 32.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 64.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC50 64.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC90 128.0 ug.mL-1 10.1128/aac.01655-08
Candida albicans Candida albicans DIZ nan None 10.1016/j.ejmech.2010.03.028
Candida albicans Candida albicans Inhibition 9.25 % 10.6019/CHEMBL4513141
Candida albicans Candida albicans IZ 10.0 mm 10.1016/j.ejmech.2009.09.002
Candida albicans Candida albicans IZ 21.0 mm 10.1016/j.ejmech.2019.111744
Candida albicans Candida albicans IZ 25.0 mm 10.1016/j.ejmech.2019.111744
Candida albicans Candida albicans MIC nan None 10.1016/j.ejmech.2010.03.028
Candida albicans Candida albicans MIC nan None 10.1016/j.ejmech.2011.04.034
Candida albicans Candida albicans MIC nan None 10.1021/acs.jnatprod.5b01129
Candida albicans Candida albicans Ratio 1.0 None 10.1016/j.ejmech.2009.09.002
Canis lupus familiaris Canis familiaris DOSE nan mg.kg-1 10.1016/j.bmcl.2004.02.068
Canis lupus familiaris MDCK logPapp -5.79 None 10.1021/jm901846t
Carnobacterium divergens Carnobacterium divergens MIC 0.75 ug.mL-1 10.1128/aac.01145-07
Carnobacterium divergens Carnobacterium divergens MIC 2.0 ug.mL-1 10.1128/aac.01145-07
Carnobacterium divergens Carnobacterium divergens MIC 4.0 ug.mL-1 10.1128/aac.01145-07
Carnobacterium divergens Carnobacterium divergens MIC 16.0 ug.mL-1 10.1128/aac.01145-07
Carnobacterium divergens Carnobacterium divergens MIC nan None 10.1128/aac.01145-07
Cavia porcellus Cavia porcellus Inhibition nan % 10.1021/jm010217j
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Chryseobacterium indologenes Chryseobacterium indologenes Activity 64.0 ug ml-1 10.1128/aac.00083-07
Chryseobacterium indologenes Chryseobacterium indologenes MIC 64.0 ug.mL-1 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-6 Kcat 480.0 /s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-6 Kcat/Km 5.6 10'6/M/s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-6 Km 85000.0 nM 10.1128/aac.01607-08
Citrobacter amalonaticus Citrobacter amalonaticus MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Citrobacter freundii Citrobacter freundii MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Citrobacter freundii Citrobacter freundii MIC 125.0 ug.mL-1 10.1016/j.bmcl.2016.03.098
Citrobacter freundii Citrobacter freundii MIC 512.0 ug.mL-1 10.1128/aac.01312-09
Citrobacter freundii Citrobacter freundii MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Citrobacter gillenii Gil1 Kcat 381.0 /s 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Kcat/Km 4540.0 /mM/s 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Km 84000.0 nM 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Ratio 81.0 None 10.1128/aac.01152-06
Citrobacter koseri Citrobacter koseri MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Clostridioides difficile Clostridioides difficile MIC 0.28 ug.mL-1 10.1016/s0960-894x(98)00206-6
Clostridioides difficile Clostridioides difficile MIC 0.28 ug.mL-1 10.1021/jm000169n
Clostridioides difficile Clostridioides difficile MIC 0.28 ug.mL-1 10.1021/jm9900671
Clostridioides difficile Clostridioides difficile MIC 0.5 ug.mL-1 10.1128/aac.00476-08
Clostridioides difficile Clostridioides difficile MIC 0.5 ug.mL-1 10.1128/aac.01557-08
Clostridioides difficile Clostridioides difficile MIC50 1.0 ug.mL-1 10.1128/aac.00476-08
Clostridioides difficile Clostridioides difficile MIC50 1.0 ug.mL-1 10.1128/aac.01557-08
Clostridioides difficile Clostridioides difficile MIC90 1.0 ug.mL-1 10.1128/aac.00476-08
Clostridioides difficile Clostridioides difficile MIC90 2.0 ug.mL-1 10.1128/aac.01557-08
Clostridium butyricum Clostridium butyricum MIC 1.0 ug.mL-1 10.1128/aac.01557-08
Clostridium cadaveris Clostridium cadaveris MIC 0.125 ug.mL-1 10.1128/aac.01557-08
[Clostridium] innocuum [Clostridium] innocuum MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Clostridium paraputrificum Clostridium paraputrificum Activity 4.0 % 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum Activity 96.0 % 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens Activity 4.0 % 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens Activity 96.0 % 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens MIC 0.027 ug.mL-1 10.1016/s0960-894x(98)00206-6
Clostridium perfringens Clostridium perfringens MIC 0.027 ug.mL-1 10.1021/jm000169n
Clostridium perfringens Clostridium perfringens MIC 0.027 ug.mL-1 10.1021/jm9900671
Clostridium perfringens Clostridium perfringens MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Clostridium perfringens Clostridium perfringens MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Clostridium perfringens Clostridium perfringens MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens MIC90 0.06 ug.mL-1 10.1016/0960-894X(95)00072-2
Clostridium perfringens Clostridium perfringens MIC90 0.06 ug.mL-1 10.1021/jm00021a013
Clostridium perfringens Clostridium perfringens MIC90 0.125 ug.mL-1 10.1128/aac.01557-08
Clostridium perfringens Clostridium perfringens MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum Activity 4.0 % 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum Activity 96.0 % 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium Activity 4.0 % 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium Activity 96.0 % 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC 0.5 ug.mL-1 10.1128/aac.01557-08
Clostridium tertium Clostridium tertium MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC50 0.5 ug.mL-1 10.1128/aac.01557-08
Clostridium tertium Clostridium tertium MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Corynebacterium striatum Corynebacterium striatum MIC 350000.0 nM 10.1021/acs.jnatprod.5b00206
Cryptococcus neoformans Cryptococcus neoformans Inhibition -2.09 % 10.6019/CHEMBL4513141
Cutibacterium acnes Cutibacterium acnes MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Cutibacterium acnes Cutibacterium acnes MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Cutibacterium acnes Cutibacterium acnes MIC90 0.25 ug.mL-1 10.1128/aac.01557-08
Dialister invisus Dialister invisus Activity 0.5 ug ml-1 10.1128/aac.00538-07
Dialister invisus Dialister invisus MIC 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus Activity 0.5 ug ml-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC50 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC90 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes Activity 0.5 ug ml-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC50 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC90 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens Activity 0.5 ug ml-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens MIC 0.06 ug.mL-1 10.1128/aac.00538-07
Edwardsiella ictaluri Edwardsiella ictaluri MIC 32.0 ug.mL-1 10.1128/aac.01312-08
Eggerthella lenta Eggerthella lenta MIC 0.5 ug.mL-1 10.1128/aac.01557-08
Eggerthella lenta Eggerthella lenta MIC50 1.0 ug.mL-1 10.1128/aac.01557-08
Eggerthella lenta Eggerthella lenta MIC90 1.0 ug.mL-1 10.1128/aac.01557-08
Enterobacter Enterobacter MIC 256.0 ug.mL-1 10.1128/aac.01614-06
Enterobacter cloacae Beta-lactamase MIC 256.0 ug.mL-1 10.1016/S0960-894X(00)80358-3
Enterobacter cloacae Enterobacter cloacae IZ 16.0 mm 10.1021/np0497447
Enterobacter cloacae Enterobacter cloacae MIC 2.0 ug.mL-1 10.1007/s00044-011-9755-5
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Enterobacter cloacae Enterobacter cloacae MIC 96.0 ug.mL-1 10.1128/aac.00163-08
Enterobacter cloacae Enterobacter cloacae MIC 100.0 ug.mL-1 10.1021/jm00178a011
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1016/j.bmcl.2016.03.098
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00033-09
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00163-08
Enterobacter cloacae Enterobacter cloacae MIC 512.0 ug.mL-1 10.1128/aac.00033-09
Enterobacter cloacae Enterobacter cloacae MIC 512.0 ug.mL-1 10.1128/aac.01082-06
Enterobacter cloacae Enterobacter cloacae MIC 512.0 ug.mL-1 10.1128/aac.01312-09
Enterobacteriaceae Enterobacteriaceae Activity 10.9 % 10.1128/aac.01519-08
Enterobacteriaceae Enterobacteriaceae Activity 45.5 % 10.1128/aac.01519-08
Enterobacteriaceae Enterobacteriaceae MIC50 4.0 ug.mL-1 10.1128/aac.01519-08
Enterobacteriaceae Enterobacteriaceae MIC50 32.0 ug.mL-1 10.1128/aac.01519-08
Enterobacteriaceae Enterobacteriaceae MIC90 4.0 ug.mL-1 10.1128/aac.01519-08
Enterobacteriaceae Enterobacteriaceae MIC90 32.0 ug.mL-1 10.1128/aac.01519-08
Enterocloster clostridioformis Enterocloster clostridioformis MIC 1.0 ug.mL-1 10.1128/aac.01557-08
Enterococcus Enterococcus MIC50 2.0 ug.mL-1 10.1021/jm0580510
Enterococcus Enterococcus MIC90 2.0 ug.mL-1 10.1021/jm0580510
Enterococcus avium Enterococcus avium MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus casseliflavus Enterococcus casseliflavus MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus durans Enterococcus durans MIC 1400.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus faecalis Enterococcus faecalis Activity 99.9 % 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis Activity nan None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis Activity nan None 10.1128/aac.00744-06
Enterococcus faecalis Enterococcus faecalis Activity nan None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/g 7.5 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/g 7.69 None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis log10CFU/g 7.69 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/g 8.55 None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 0.79 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 1.1 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 1.45 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 1.5 None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 1.73 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 2.07 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 2.46 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 2.48 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 2.57 None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 2.83 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 3.15 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 3.93 None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 4.44 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 4.59 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 4.86 None 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 5.59 None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 6.46 None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis log10CFU/ml 7.82 None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis MBC 2.0 ug ml-1 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis MBC 1024.0 ug ml-1 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis MBC50 16.0 mg/L 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MBC50 64.0 mg/L 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MBC90 64.0 mg/L 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MBC90 128.0 mg/L 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1016/j.bmcl.2016.03.098
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1016/j.ejmech.2011.02.066
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1128/aac.00744-06
Enterococcus faecalis Enterococcus faecalis MIC 0.39 ug.mL-1 10.1016/s0960-894x(98)00335-7
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2010.11.102
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1016/j.ejmech.2014.07.106
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.7b00108
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1021/jm025502x
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1128/aac.00744-06
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1128/aac.01230-10
Enterococcus faecalis Enterococcus faecalis MIC 0.78 ug.mL-1 10.1016/s0960-894x(03)00547-x
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1128/aac.00744-06
Enterococcus faecalis Enterococcus faecalis MIC 1.22 ug.mL-1 10.1016/j.ejmech.2010.09.049
Enterococcus faecalis Enterococcus faecalis MIC 1.25 ug.mL-1 10.1039/C8MD00212F
Enterococcus faecalis Enterococcus faecalis MIC 1.6 ug.mL-1 10.1021/jm00178a011
Enterococcus faecalis Enterococcus faecalis MIC 1.62 ug.mL-1 10.1016/j.ejmech.2011.02.051
Enterococcus faecalis Enterococcus faecalis MIC 4.0 ug.mL-1 10.1016/j.bmc.2010.03.045
Enterococcus faecalis Enterococcus faecalis MIC 490.0 nM 10.1021/jm031089x
Enterococcus faecalis Enterococcus faecalis MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus faecalis Enterococcus faecalis MIC 1400.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus faecalis Enterococcus faecalis MIC 2000.0 nM 10.1016/j.ejmech.2017.01.038
Enterococcus faecalis Enterococcus faecalis MIC 3000.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus faecalis Enterococcus faecalis MIC 8000.0 nM 10.1021/acsmedchemlett.1c00683
Enterococcus faecalis Enterococcus faecalis MIC 64000.0 nM 10.1021/acsmedchemlett.1c00683
Enterococcus faecalis Enterococcus faecalis MIC 64000000.0 nM 10.1016/j.ejmech.2008.02.021
Enterococcus faecalis Enterococcus faecalis MIC50 4.0 ug.mL-1 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MIC50 16.0 ug.mL-1 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MIC90 0.5 ug.mL-1 10.1016/0960-894X(95)00072-2
Enterococcus faecalis Enterococcus faecalis MIC90 0.5 ug.mL-1 10.1021/jm00021a013
Enterococcus faecalis Enterococcus faecalis MIC90 16.0 ug.mL-1 10.1021/jm025502x
Enterococcus faecalis Enterococcus faecalis MIC90 16.0 ug.mL-1 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MIC90 64.0 ug.mL-1 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis Ratio 4.0 None 10.1128/aac.00692-08
Enterococcus faecalis Enterococcus faecalis Ratio 32.0 None 10.1128/aac.00692-08
Enterococcus faecalis (strain ATCC 700802 / V583) Methionyl-tRNA synthetase MIC90 16.0 ug.mL-1 10.1016/s0960-894x(02)01027-2
Enterococcus faecium Enterococcus faecium MIC 16.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Enterococcus faecium Enterococcus faecium MIC 16.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Enterococcus faecium Enterococcus faecium MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.7b00108
Enterococcus faecium Enterococcus faecium MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus faecium Enterococcus faecium MIC 1300.0 nM 10.1021/acs.jmedchem.1c01482
Enterococcus faecium Enterococcus faecium MIC 22000.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus faecium Enterococcus faecium MIC 60000.0 nM 10.1016/j.ejmech.2017.01.038
Enterococcus faecium Enterococcus faecium MIC 175000.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus faecium Enterococcus faecium MIC 250000.0 nM 10.1016/j.ejmech.2017.01.038
Enterococcus faecium Enterococcus faecium MIC 350000.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus faecium Enterococcus faecium MIC 500000.0 nM 10.1016/j.ejmech.2017.01.038
Enterococcus faecium Enterococcus faecium MIC 8000000.0 nM 10.1016/j.ejmech.2008.02.021
Enterococcus faecium Enterococcus faecium MIC90 16.0 ug.mL-1 10.1021/jm025502x
Enterococcus faecium Enterococcus faecium MIC90 32.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Enterococcus faecium Enterococcus faecium MIC90 32.0 ug.mL-1 10.1021/jm00021a013
Enterococcus gallinarum Enterococcus gallinarum MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus gallinarum Enterococcus gallinarum MIC 1400.0 nM 10.1021/acs.jnatprod.5b00206
Enterococcus hirae Enterococcus hirae MIC 1400.0 nM 10.1021/acs.jnatprod.5b00206
Escherichia coli Beta-lactamase SHV-1 Kcat 1044.0 /s 10.1128/aac.01442-09
Escherichia coli Beta-lactamase SHV-1 Kcat/Km 33.7 /uM/s 10.1128/aac.01442-09
Escherichia coli Beta-lactamase SHV-1 Km 31000.0 nM 10.1128/aac.01442-09
Escherichia coli Beta-lactamase TEM Activity 108.0 None 10.1128/aac.01439-06
Escherichia coli Beta-lactamase TEM Kcat 1125.0 /s 10.1128/aac.00614-07
Escherichia coli Beta-lactamase TEM Kcat/Km 75.0 None 10.1128/aac.00614-07
Escherichia coli Beta-lactamase TEM Km 15.0 /s/microM 10.1128/aac.00614-07
Escherichia coli Beta-lactamase TEM MIC 256.0 ug.mL-1 10.1016/S0960-894X(00)80358-3
Escherichia coli BlaVIM-1 Kcat nan None 10.1128/aac.00017-09
Escherichia coli CMT-type beta lactamase Kcat 14.4 /s 10.1128/aac.00614-07
Escherichia coli CMT-type beta lactamase Kcat/Km 0.58 None 10.1128/aac.00614-07
Escherichia coli CMT-type beta lactamase Km 24.8 /s/microM 10.1128/aac.00614-07
Escherichia coli Escherichia coli Activity 0.29 log10CFU/ml 10.1021/acs.jmedchem.2c01604
Escherichia coli Escherichia coli Activity 2.0 ug ml-1 10.1128/aac.00083-07
Escherichia coli Escherichia coli Activity 2.3 log10CFU/ml 10.1021/acs.jmedchem.1c00437
Escherichia coli Escherichia coli Activity 2.4 log10CFU/ml 10.1021/acs.jmedchem.1c00437
Escherichia coli Escherichia coli Activity 3.7 log10CFU/ml 10.1021/acs.jmedchem.1c00437
Escherichia coli Escherichia coli Activity 30.2 % 10.1128/aac.00063-08
Escherichia coli Escherichia coli Activity 64.0 ug ml-1 10.1128/aac.00083-07
Escherichia coli Escherichia coli Activity 74.0 % 10.1128/aac.00061-09
Escherichia coli Escherichia coli Activity nan None 10.1021/acs.jmedchem.0c00040
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00614-07
Escherichia coli Escherichia coli Antibiotic resistance nan None 10.1016/s0960-894x(98)00536-8
Escherichia coli Escherichia coli FC 16.0 None 10.1021/acs.jmedchem.2c01604
Escherichia coli Escherichia coli IC50 1.9 ug.mL-1 10.1016/j.ejmech.2007.12.008
Escherichia coli Escherichia coli Inhibition 7.14 % 10.6019/CHEMBL4513141
Escherichia coli Escherichia coli IZ 0.0 mm 10.1016/j.ejmech.2017.11.001
Escherichia coli Escherichia coli IZ 8.0 mm 10.1007/s00044-012-0011-4
Escherichia coli Escherichia coli IZ 11.0 mm 10.1016/j.ejmech.2010.12.005
Escherichia coli Escherichia coli IZ 12.0 mm 10.1016/j.ejmech.2011.12.012
Escherichia coli Escherichia coli IZ 13.0 mm 10.1016/j.ejmech.2010.03.028
Escherichia coli Escherichia coli IZ 13.26 mm 10.1007/s00044-007-9017-8
Escherichia coli Escherichia coli IZ 14.0 mm 10.1007/s00044-009-9214-8
Escherichia coli Escherichia coli IZ 14.0 mm 10.1007/s00044-012-0039-5
Escherichia coli Escherichia coli IZ 14.9 mm 10.1039/d2md00076h
Escherichia coli Escherichia coli IZ 15.0 mm 10.1016/j.ejmech.2010.08.005
Escherichia coli Escherichia coli IZ 15.5 mm 10.1007/s00044-012-0084-0
Escherichia coli Escherichia coli IZ 16.0 mm 10.1007/s00044-010-9440-0
Escherichia coli Escherichia coli IZ 16.0 mm 10.1021/np0497447
Escherichia coli Escherichia coli IZ 18.0 mm 10.1007/s00044-011-9857-0
Escherichia coli Escherichia coli IZ 18.5 mm 10.1016/j.ejmech.2010.08.005
Escherichia coli Escherichia coli IZ 18.7 mm 10.1007/s00044-012-0084-0
Escherichia coli Escherichia coli IZ 19.5 mm 10.1016/j.bmc.2019.02.044
Escherichia coli Escherichia coli IZ 19.5 mm 10.1039/d2md00076h
Escherichia coli Escherichia coli IZ 20.0 mm 10.1007/s00044-012-0032-z
Escherichia coli Escherichia coli IZ 20.0 mm 10.1007/s00044-012-0155-2
Escherichia coli Escherichia coli IZ 20.0 mm 10.1016/j.ejmech.2007.12.004
Escherichia coli Escherichia coli IZ 20.0 mm 10.1016/j.ejmech.2007.12.008
Escherichia coli Escherichia coli IZ 20.0 mm 10.1016/j.ejmech.2008.06.008
Escherichia coli Escherichia coli IZ 20.0 mm 10.1016/j.ejmech.2008.09.029
Escherichia coli Escherichia coli IZ 20.2 mm 10.1016/j.ejmech.2008.09.004
Escherichia coli Escherichia coli IZ 21.0 mm 10.1016/j.ejmech.2017.05.010
Escherichia coli Escherichia coli IZ 21.0 mm 10.1016/j.ejmech.2019.111744
Escherichia coli Escherichia coli IZ 22.05 mm 10.1016/j.ejmech.2011.04.013
Escherichia coli Escherichia coli IZ 22.6 mm 10.1016/j.ejmech.2014.03.037
Escherichia coli Escherichia coli IZ 23.0 mm 10.1007/s00044-009-9184-x
Escherichia coli Escherichia coli IZ 24.0 mm 10.1039/d2md00076h
Escherichia coli Escherichia coli IZ 25.0 mm 10.1007/s00044-010-9354-x
Escherichia coli Escherichia coli IZ 25.0 mm 10.1016/j.bmcl.2015.07.071
Escherichia coli Escherichia coli IZ 25.0 mm 10.1016/j.ejmech.2019.111744
Escherichia coli Escherichia coli IZ 28.0 mm 10.1007/s00044-010-9440-0
Escherichia coli Escherichia coli IZ 28.0 mm 10.1016/j.ejmech.2009.09.002
Escherichia coli Escherichia coli IZ 30.0 mm 10.1007/s00044-011-9634-0
Escherichia coli Escherichia coli IZ 30.0 mm 10.1016/j.ejmech.2009.02.020
Escherichia coli Escherichia coli IZ 30.0 mm 10.1016/j.ejmech.2020.112832
Escherichia coli Escherichia coli IZ 36.0 mm 10.1016/j.ejmech.2020.113034
Escherichia coli Escherichia coli log(activity) 1.22 None 10.1021/acs.jmedchem.0c02059
Escherichia coli Escherichia coli MBC 76.2 mg/L 10.1007/s00044-011-9933-5
Escherichia coli Escherichia coli MBC 100.0 mg/L 10.1007/s00044-011-9933-5
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1016/j.bmcl.2012.08.084
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1007/s00044-011-9733-y
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1016/j.bmcl.2015.07.071
Escherichia coli Escherichia coli MIC 0.32 ug.mL-1 10.1016/j.ejmech.2022.114502
Escherichia coli Escherichia coli MIC 0.39 ug.mL-1 10.1016/j.ejmech.2015.03.021
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.bmc.2010.03.045
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.ejmech.2011.02.066
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 0.8 ug.mL-1 10.1016/j.bmcl.2015.06.010
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01672-07
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1016/j.ejmech.2017.05.010
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1128/aac.01145-07
Escherichia coli Escherichia coli MIC 1.6 ug.mL-1 10.1016/s0960-894x(03)00547-x
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1007/s00044-011-9755-5
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2016.03.098
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.ejmech.2018.08.095
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00033-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00050-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00387-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00791-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01152-06
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01164-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01247-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01252-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01442-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01463-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01600-06
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.00547-09
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 3.12 ug.mL-1 10.1007/s00044-011-9634-0
Escherichia coli Escherichia coli MIC 3.12 ug.mL-1 10.1016/j.ejmech.2007.01.022
Escherichia coli Escherichia coli MIC 3.12 ug.mL-1 10.1016/j.ejmech.2007.12.008
Escherichia coli Escherichia coli MIC 3.13 ug.mL-1 10.1016/s0960-894x(98)00335-7
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1007/s00044-012-0011-4
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1016/j.bmc.2015.08.031
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1016/j.ejmech.2012.03.008
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00580
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00033-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00175-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00219-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00242-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00387-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00427-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00436-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00458-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00543-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00614-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00770-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00856-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00859-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00878-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00912-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00946-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00961-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01082-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01164-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01180-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01247-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01312-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01439-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01456-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01581-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01585-09
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1021/acs.jnatprod.1c00222
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1128/aac.00684-07
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1128/aac.01585-09
Escherichia coli Escherichia coli MIC 6.2 ug.mL-1 10.1021/jm00178a011
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1007/s00044-010-9354-x
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1039/C8MD00212F
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.bmcl.2010.05.110
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00393-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01028-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01247-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01442-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01581-08
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1007/s00044-012-0270-0
Escherichia coli Escherichia coli MIC 15.32 ug.mL-1 10.1016/j.ejmech.2011.02.051
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00033-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00909-06
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00946-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00961-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01247-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01463-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Escherichia coli Escherichia coli MIC 16.43 ug.mL-1 10.1016/j.ejmech.2010.09.049
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1016/j.ejmech.2010.12.005
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1016/j.ejmech.2011.12.012
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1128/aac.00436-09
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1007/s00044-012-0155-2
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2007.12.004
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2008.06.008
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2008.09.004
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2011.04.013
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00547-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01164-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01247-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01252-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01312-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 48.0 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 48.0 ug.mL-1 10.1128/aac.00944-09
Escherichia coli Escherichia coli MIC 63.0 ug.mL-1 10.1021/jm00144a034
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00547-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01028-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01442-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 125.0 ug.mL-1 10.1021/jm00144a034
Escherichia coli Escherichia coli MIC 125.0 ug.mL-1 10.1021/jm00382a025
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00427-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00909-06
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 150.0 ug.mL-1 10.1016/j.ejmech.2012.12.034
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1016/j.ejmech.2010.03.028
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1016/j.ejmech.2011.04.034
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00050-10
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00175-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00242-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00387-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00393-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00543-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00684-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00770-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00912-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00944-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00961-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01145-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01164-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01180-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01439-06
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01585-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00033-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00219-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00387-08
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00458-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00791-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00856-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00859-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00878-10
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00946-08
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01082-06
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01152-06
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01164-08
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01442-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01456-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01600-06
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01672-07
Escherichia coli Escherichia coli MIC 513.0 ug.mL-1 10.1128/aac.01672-07
Escherichia coli Escherichia coli MIC 1000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 1024.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 1700.0 nM 10.1039/d1md00091h
Escherichia coli Escherichia coli MIC 2000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 2048.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 2048.0 ug.mL-1 10.1128/aac.00387-08
Escherichia coli Escherichia coli MIC 2048.0 ug.mL-1 10.1128/aac.00614-07
Escherichia coli Escherichia coli MIC 2048.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 2048.0 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 2048.0 ug.mL-1 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 2048.0 ug.mL-1 10.1128/aac.01442-09
Escherichia coli Escherichia coli MIC 2700.0 nM 10.1021/acs.jnatprod.5b01129
Escherichia coli Escherichia coli MIC 4000.0 ug.mL-1 10.1007/s00044-012-0202-z
Escherichia coli Escherichia coli MIC 4000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 4096.0 ug.mL-1 10.1128/aac.00387-08
Escherichia coli Escherichia coli MIC 4096.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 8000.0 nM 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 8000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 11000.0 nM 10.1039/d1md00091h
Escherichia coli Escherichia coli MIC 16000.0 nM 10.1021/acsmedchemlett.1c00683
Escherichia coli Escherichia coli MIC 16000.0 nM 10.1021/acsmedchemlett.3c00093
Escherichia coli Escherichia coli MIC 18000.0 nM 10.1021/acs.jmedchem.1c01482
Escherichia coli Escherichia coli MIC 22000.0 nM 10.1016/j.bmc.2007.05.028
Escherichia coli Escherichia coli MIC 32000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 64000.0 nM 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 512000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.01472-06
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.01607-08
Escherichia coli Escherichia coli MIC50 1.6 ug.mL-1 10.1007/s00044-011-9634-0
Escherichia coli Escherichia coli MIC50 100.0 ug.mL-1 10.1016/j.bmcl.2007.08.021
Escherichia coli Escherichia coli MIC90 4170.0 nM 10.1016/j.ejmech.2019.111615
Escherichia coli Escherichia coli MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Escherichia coli Escherichia coli Ratio 1.0 None 10.1016/j.ejmech.2009.09.002
Escherichia coli Escherichia coli Ratio 1.0 None 10.1016/j.ejmech.2012.03.008
Escherichia coli Metallo-beta-lactamase Kcat 29.7 /s 10.1128/aac.00017-09
Escherichia coli Metallo-beta-lactamase Kcat/Km 0.55 /s/microM 10.1128/aac.00017-09
Escherichia coli K-12 Beta-lactamase AmpC Km 27.3 ug ml-1 10.1016/s0960-894x(99)00549-1
Escherichia coli K-12 Beta-lactamase AmpC Potency 35481.3 nM None
Escherichia coli K-12 Beta-lactamase AmpC Vmax 0.0175 None 10.1016/s0960-894x(99)00549-1
Escherichia coli K-12 Beta-lactamase AmpC Vmax / Km 0.0521 None 10.1016/s0960-894x(99)00549-1
Escherichia coli K-12 Methionyl-tRNA synthetase MIC90 16.0 ug.mL-1 10.1016/s0960-894x(02)01027-2
Finegoldia magna Finegoldia magna Activity 3.0 % 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna Activity 94.0 % 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Finegoldia magna Finegoldia magna MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna MIC50 0.25 ug.mL-1 10.1128/aac.01557-08
Finegoldia magna Finegoldia magna MIC90 0.25 ug.mL-1 10.1128/aac.01557-08
Finegoldia magna Finegoldia magna MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Fusarium oxysporum Fusarium oxysporum MIC 2.0 ug.mL-1 10.1007/s00044-011-9755-5
Fusobacterium mortiferum Fusobacterium mortiferum Activity 7.0 % 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum Activity 89.0 % 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC 0.5 ug.mL-1 10.1128/aac.01557-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC50 1.0 ug.mL-1 10.1128/aac.01557-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC50 2.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC90 32.0 ug.mL-1 10.1128/aac.01557-08
Fusobacterium necrophorum Fusobacterium necrophorum Activity 7.0 % 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum Activity 89.0 % 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC50 2.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum Activity 7.0 % 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum Activity 89.0 % 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum Activity nan None 10.1128/aac.00924-06
Fusobacterium nucleatum Fusobacterium nucleatum MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC50 2.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC90 0.125 ug.mL-1 10.1128/aac.01557-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium Activity 7.0 % 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium Activity 89.0 % 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium MIC 1.0 ug.mL-1 10.1128/aac.01557-08
Fusobacterium varium Fusobacterium varium MIC50 2.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium MIC50 2.0 ug.mL-1 10.1128/aac.01557-08
Fusobacterium varium Fusobacterium varium MIC90 2.0 ug.mL-1 10.1128/aac.01557-08
Fusobacterium varium Fusobacterium varium MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Geotrichum candidum Geotrichum candidum IZ 10.0 mm 10.1016/j.ejmech.2009.09.002
Geotrichum candidum Geotrichum candidum Ratio 1.0 None 10.1016/j.ejmech.2009.09.002
Gerbillinae Gerbillinae Ratio 0.0 % 10.1016/s0960-894x(98)00390-4
Gerbillinae Gerbillinae Ratio 100.0 % 10.1016/s0960-894x(98)00390-4
Haemophilus influenzae Haemophilus influenzae Activity 0.0 % 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae Activity 0.0 % 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae Activity 0.0 ug ml-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae Activity 0.3 % 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae Activity 4.8 % 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae Activity 5.0 % 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae Activity 9.9 % 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae Activity 20.6 % 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae Activity 25.0 % 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae Activity 27.0 % 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae Activity 35.3 % 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae Activity 67.6 % 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae Activity 85.0 % 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae Activity 97.5 % 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae Activity 99.7 % 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae Activity 100.0 % 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae Activity 100.0 % 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC 0.015 ug.mL-1 10.1016/j.bmc.2010.03.045
Haemophilus influenzae Haemophilus influenzae MIC 0.12 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1016/j.bmcl.2010.11.102
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1016/j.ejmech.2014.07.106
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.01326-07
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.00936-07
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.01489-09
Haemophilus influenzae Haemophilus influenzae MIC 1.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC 1.0 ug.mL-1 10.1128/aac.00936-07
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1128/aac.00936-07
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC 32.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Haemophilus influenzae Haemophilus influenzae MIC 32.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Haemophilus influenzae Haemophilus influenzae MIC 32.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC 64.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Haemophilus influenzae Haemophilus influenzae MIC 64.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Haemophilus influenzae Haemophilus influenzae MIC 64.0 ug.mL-1 10.1128/aac.01489-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.25 ug.mL-1 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.5 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC50 0.5 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.5 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC50 0.5 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC50 1.0 ug.mL-1 10.1021/jm0580510
Haemophilus influenzae Haemophilus influenzae MIC50 1.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC50 2.0 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC50 2.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC50 2.0 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC50 2.0 ug.mL-1 10.1128/aac.01326-07
Haemophilus influenzae Haemophilus influenzae MIC50 4.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC50 4.0 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC50 8.0 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC50 8.0 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC50 32.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC50 64.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC90 0.5 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC90 0.5 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC90 1.0 % 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae MIC90 1.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Haemophilus influenzae Haemophilus influenzae MIC90 1.0 ug.mL-1 10.1021/jm00021a013
Haemophilus influenzae Haemophilus influenzae MIC90 1.0 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC90 2.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC90 4.0 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC90 4.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC90 4.0 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC90 8.0 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC90 8.0 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC90 16.0 ug.mL-1 10.1128/aac.00214-08
Haemophilus influenzae Haemophilus influenzae MIC90 32.0 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC90 32.0 ug.mL-1 10.1128/aac.01326-07
Haemophilus influenzae Haemophilus influenzae MIC90 64.0 ug.mL-1 10.1021/jm0580510
Haemophilus influenzae Haemophilus influenzae MIC90 64.0 ug.mL-1 10.1128/aac.00214-08
Helicobacter pylori Helicobacter pylori Activity 1.0 g 10.1128/aac.00049-09
Helicobacter pylori Helicobacter pylori Activity 24.5 mm 10.1016/j.bmcl.2008.04.033
Helicobacter pylori Helicobacter pylori Activity 33.3 % 10.1128/aac.00049-09
Helicobacter pylori Helicobacter pylori Activity 66.0 % 10.1128/aac.00049-09
Helicobacter pylori Helicobacter pylori Activity 84.4 % 10.1128/aac.00049-09
Helicobacter pylori Helicobacter pylori Activity 274.0 uM 10.1021/np5003252
Helicobacter pylori Helicobacter pylori Inhibition 81.9 % 10.1016/j.bmcl.2010.07.094
Helicobacter pylori Helicobacter pylori Inhibition 90.0 % 10.1016/j.bmcl.2010.07.094
Helicobacter pylori Helicobacter pylori Inhibition nan % 10.1016/j.bmcl.2010.07.094
Helicobacter pylori Helicobacter pylori IZ 14.0 mm 10.1016/j.bmcl.2010.07.094
Helicobacter pylori Helicobacter pylori IZ 20.3 mm 10.1021/np040188q
Helicobacter pylori Helicobacter pylori IZ 24.5 mm 10.1007/s00044-008-9099-y
Helicobacter pylori Helicobacter pylori IZ 24.5 mm 10.1016/j.ejmech.2007.11.019
Helicobacter pylori Helicobacter pylori IZ 33.0 mm 10.1021/np060217s
Helicobacter pylori Helicobacter pylori IZ 35.3 mm 10.1021/np040188q
Helicobacter pylori Helicobacter pylori log10CFU/ml 0.51 None 10.1021/np5003252
Helicobacter pylori Helicobacter pylori MBC 0.05 ug ml-1 10.1021/jm0208673
Helicobacter pylori Helicobacter pylori MBC 0.05 ug ml-1 10.1021/jm970165r
Helicobacter pylori Helicobacter pylori MBC 12.5 uM 10.1016/j.bmcl.2010.07.094
Helicobacter pylori Helicobacter pylori MIC 0.0125 ug.mL-1 10.1016/s0960-894x(99)00549-1
Helicobacter pylori Helicobacter pylori MIC 0.021 ug.mL-1 10.1016/s0960-894x(98)00206-6
Helicobacter pylori Helicobacter pylori MIC 0.021 ug.mL-1 10.1021/jm000169n
Helicobacter pylori Helicobacter pylori MIC 0.021 ug.mL-1 10.1021/jm010217j
Helicobacter pylori Helicobacter pylori MIC 0.021 ug.mL-1 10.1021/jm9900671
Helicobacter pylori Helicobacter pylori MIC 0.025 ug.mL-1 10.1016/j.bmcl.2004.02.068
Helicobacter pylori Helicobacter pylori MIC 0.025 ug.mL-1 10.1016/s0960-894x(03)00547-x
Helicobacter pylori Helicobacter pylori MIC 0.025 ug.mL-1 10.1016/s0960-894x(98)00335-7
Helicobacter pylori Helicobacter pylori MIC 0.025 ug.mL-1 10.1016/s0960-894x(99)00203-6
Helicobacter pylori Helicobacter pylori MIC 0.025 ug.mL-1 10.1016/s0960-894x(99)00549-1
Helicobacter pylori Helicobacter pylori MIC 0.03 ug.mL-1 10.1128/aac.01242-08
Helicobacter pylori Helicobacter pylori MIC 0.031 ug.mL-1 10.1021/jm010307o
Helicobacter pylori Helicobacter pylori MIC 0.05 ug.mL-1 10.1016/j.bmcl.2004.02.068
Helicobacter pylori Helicobacter pylori MIC 0.05 ug.mL-1 10.1016/s0960-894x(03)00547-x
Helicobacter pylori Helicobacter pylori MIC 0.05 ug.mL-1 10.1016/s0960-894x(99)00203-6
Helicobacter pylori Helicobacter pylori MIC 0.05 ug.mL-1 10.1016/s0960-894x(99)00549-1
Helicobacter pylori Helicobacter pylori MIC 0.06 ug.mL-1 10.1021/jm020868v
Helicobacter pylori Helicobacter pylori MIC 0.06 ug.mL-1 10.1021/np040188q
Helicobacter pylori Helicobacter pylori MIC 0.1 ug.mL-1 10.1016/s0960-894x(98)00335-7
Helicobacter pylori Helicobacter pylori MIC 0.1 ug.mL-1 10.1016/s0960-894x(99)00203-6
Helicobacter pylori Helicobacter pylori MIC 0.12 ug.mL-1 10.1021/jm020868v
Helicobacter pylori Helicobacter pylori MIC 0.125 ug.mL-1 10.1021/jm010307o
Helicobacter pylori Helicobacter pylori MIC 0.13 ug.mL-1 10.1021/np040188q
Helicobacter pylori Helicobacter pylori MIC 0.2 ug.mL-1 10.1016/j.bmcl.2004.02.068
Helicobacter pylori Helicobacter pylori MIC 0.25 ug.mL-1 10.1021/np040188q
Helicobacter pylori Helicobacter pylori MIC 0.5 ug.mL-1 10.1021/jm010307o
Helicobacter pylori Helicobacter pylori MIC 0.5 ug.mL-1 10.1021/np040188q
Helicobacter pylori Helicobacter pylori MIC 0.781 ug.mL-1 10.1016/j.bmcl.2006.08.043
Helicobacter pylori Helicobacter pylori MIC 25.0 ug.mL-1 10.1016/s0960-894x(98)00390-4
Helicobacter pylori Helicobacter pylori MIC 80.0 nM 10.1021/np070260v
Helicobacter pylori Helicobacter pylori MIC 140.0 nM 10.1016/j.ejmech.2020.112994
Helicobacter pylori Helicobacter pylori MIC 1070.0 nM 10.1016/j.ejmech.2020.112994
Helicobacter pylori Helicobacter pylori MIC50 0.0125 ug.mL-1 10.1016/j.bmcl.2004.02.068
Helicobacter pylori Helicobacter pylori MIC50 0.05 ug.mL-1 10.1016/j.bmcl.2004.02.068
Helicobacter pylori Helicobacter pylori MIC50 0.8 ug.mL-1 10.1016/j.bmc.2015.05.026
Helicobacter pylori Helicobacter pylori MIC90 0.125 ug.mL-1 10.1016/j.bmcl.2014.04.041
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Beta-1 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile acid receptor FXR AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump AC50 300000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Bile salt export pump IC50 1000000.0 nM 10.1124/dmd.111.040758
Homo sapiens Bile salt export pump IC50 1000000.0 nM 10.1124/dmd.112.047068
Homo sapiens Bradykinin B1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Caco-2 logPapp -6.73 None 10.1016/j.bmc.2011.03.011
Homo sapiens Caco-2 logPapp -6.1 None 10.1016/j.bmc.2009.08.022
Homo sapiens Caco-2 permeability nan None 10.1016/j.bmc.2011.03.011
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Corticotropin releasing factor receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Corticotropin releasing factor receptor 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C9 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 2J2 IC50 50000.0 nM 10.1124/dmd.112.048264
Homo sapiens Cytochrome P450 3A4 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 1412.5 nM None
Homo sapiens DNA polymerase eta Potency 37933.0 nM None
Homo sapiens DNA polymerase eta Potency 79432.8 nM None
Homo sapiens DNA polymerase iota Potency 44668.4 nM None
Homo sapiens DNA polymerase kappa Potency 50118.7 nM None
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine D5 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Endothelin receptor ET-B AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens GABA-B receptor 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Gastric inhibitory polypeptide receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucagon receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens HaCaT IC50 29410.0 nM 10.1039/d1md00091h
Homo sapiens HEK293 CC50 24000.0 nM 10.1016/j.bmcl.2014.03.097
Homo sapiens HeLa Activity nan None 10.1128/aac.00729-05
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Ki nan None None
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone deacetylase 6 Inhibition -3.71 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition -3.53 % 10.6019/CHEMBL4808148
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens Activity 0.93 % 10.1016/j.ejmech.2009.11.034
Homo sapiens Homo sapiens AUC 68000.0 ng.hr.mL-1 10.1128/aac.00004-06
Homo sapiens Homo sapiens CL 1.4 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 3.3 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL 3.3 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 7.63 L/hr 10.1128/aac.00636-08
Homo sapiens Homo sapiens CL_renal 1.89 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL_renal 1.9 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens Cmax 51996.39 nM 10.1128/aac.00004-06
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 5.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens F 45.0 % 10.1021/jm901846t
Homo sapiens Homo sapiens Fa 0.93 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fa 90.0 % 10.1021/jm991156g
Homo sapiens Homo sapiens F_fraction 0.77 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fg 0.88 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fh 0.94 None 10.1021/jm901371v
Homo sapiens Homo sapiens Peff 0.3 None 10.1021/jm9810102
Homo sapiens Homo sapiens T1/2 1.5 hr 10.1128/aac.00004-06
Homo sapiens Homo sapiens Vd 0.41 L.kg-1 10.1128/aac.00318-07
Homo sapiens Homo sapiens Vdss 0.25 L.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens Vdss 0.85 L.kg-1 10.1016/j.ejmech.2009.06.004
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Kappa opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens Liver microsomes Activity nan None 10.1021/tx300075j
Homo sapiens Liver microsomes Stability nan % 10.1021/tx300075j
Homo sapiens LXR-alpha AC50 18999.8 nM 10.1038/s41467-023-40064-9
Homo sapiens LXR-alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens LXR-beta AC50 4100.0 nM 10.1038/s41467-023-40064-9
Homo sapiens LXR-beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Lysine-specific demethylase 4D-like Potency 31622.8 nM None
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens MG-63 Activity nan None 10.1128/aac.00729-05
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Multidrug resistance-associated protein 4 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Mu opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Neurotensin receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens NHDF LD50 512.0 uM 10.1021/acsmedchemlett.1c00683
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens Nuclear receptor subfamily 1 group I member 3 AC50 15000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Oligopeptide transporter small intestine isoform Activity 62.9 % None
Homo sapiens Oligopeptide transporter small intestine isoform Activity 85.7 % None
Homo sapiens Oligopeptide transporter small intestine isoform Ki 10000000.0 nM 10.1016/j.ejpb.2004.07.008
Homo sapiens Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Potency 50118.7 nM None
Homo sapiens Peroxisome proliferator-activated receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Phosphodiesterase 6A AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Plasma fCmax 33.66 uM 10.1124/dmd.111.040758
Homo sapiens Plasma Kel 0.33 /hr 10.1128/aac.00636-08
Homo sapiens Plasma Vd 0.713 L.kg-1 10.1128/aac.00636-08
Homo sapiens Plasma Vd 1.03 L.kg-1 10.1128/aac.00636-08
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Retinoic acid receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoic acid receptor beta AC50 17999.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoic acid receptor beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoic acid receptor gamma AC50 9100.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoic acid receptor gamma AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 5a (5-HT5a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin 7 (5-HT7) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Serum albumin Log K' 1.21 None 10.1021/jm010960b
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens Sodium channel protein type V alpha subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Solute carrier family 15 member 2 Ki 426579.52 nM 10.1016/j.bmc.2011.06.027
Homo sapiens Solute carrier family 15 member 2 Ki 430000.0 nM 10.1016/j.bmc.2011.06.027
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 75.16 % 10.1124/mol.112.084152
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 87.94 % 10.1124/mol.112.084152
Homo sapiens Thromboxane A2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Hoylesella loescheii Hoylesella loescheii MIC 0.25 ug.mL-1 10.1128/aac.01557-08
Hoylesella oralis Hoylesella oralis MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Klebsiella aerogenes Klebsiella aerogenes IZ 10.0 mm 10.1016/j.ejmech.2020.113034
Klebsiella aerogenes Klebsiella aerogenes MIC 3.45 ug.mL-1 10.1016/j.ejmech.2011.02.051
Klebsiella aerogenes Klebsiella aerogenes MIC 3.65 ug.mL-1 10.1016/j.ejmech.2010.09.049
Klebsiella aerogenes Klebsiella aerogenes MIC 64.0 ug.mL-1 10.1128/aac.01028-07
Klebsiella aerogenes Klebsiella aerogenes MIC 100.0 ug.mL-1 10.1021/jm00178a011
Klebsiella aerogenes Klebsiella aerogenes MIC 8100.0 nM 10.1021/jm031089x
Klebsiella aerogenes Klebsiella aerogenes MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Klebsiella oxytoca Klebsiella oxytoca MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat 1044.0 /s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat 1044.0 /s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat/Km 33.3 /uM/s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat/Km 33.7 /uM/s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Km 31000.0 nM 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Km 31000.0 nM 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-55 Kcat 23.0 /s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-55 Kcat/Km 2.5 /uM/s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-55 Km 10000.0 nM 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-72 Kcat 5876.0 /s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-72 Kcat/Km 226.0 /uM/s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-72 Km 26000.0 nM 10.1128/aac.01381-07
Klebsiella pneumoniae Extended spectrum beta-lactamase CTX-M-71 Kcat 49.0 /s 10.1128/aac.00461-09
Klebsiella pneumoniae Extended spectrum beta-lactamase CTX-M-71 Km 5200.0 nM 10.1128/aac.00461-09
Klebsiella pneumoniae Extended spectrum beta-lactamase CTX-M-71 Ratio 9.4 None 10.1128/aac.00461-09
Klebsiella pneumoniae Klebsiella pneumoniae Inhibition 10.29 % 10.6019/CHEMBL4513141
Klebsiella pneumoniae Klebsiella pneumoniae IZ 6.0 mm 10.1016/j.ejmech.2017.11.001
Klebsiella pneumoniae Klebsiella pneumoniae IZ 8.0 mm 10.1007/s00044-012-0011-4
Klebsiella pneumoniae Klebsiella pneumoniae IZ 8.0 mm 10.1016/j.ejmech.2010.12.005
Klebsiella pneumoniae Klebsiella pneumoniae IZ 8.0 mm 10.1016/j.ejmech.2011.12.012
Klebsiella pneumoniae Klebsiella pneumoniae IZ 11.0 mm 10.1021/np0497447
Klebsiella pneumoniae Klebsiella pneumoniae IZ 13.6 mm 10.1039/d2md00076h
Klebsiella pneumoniae Klebsiella pneumoniae IZ 15.0 mm 10.1039/d2md00076h
Klebsiella pneumoniae Klebsiella pneumoniae IZ 17.0 mm 10.1021/np970294a
Klebsiella pneumoniae Klebsiella pneumoniae IZ 18.0 mm 10.1016/j.bmc.2019.02.044
Klebsiella pneumoniae Klebsiella pneumoniae IZ 18.0 mm 10.1039/d2md00076h
Klebsiella pneumoniae Klebsiella pneumoniae MBC 100.0 mg/L 10.1007/s00044-011-9933-5
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.8 ug.mL-1 10.1021/jm00178a011
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00657-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 12.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 20.0 ug.mL-1 10.1016/j.ejmech.2010.12.005
Klebsiella pneumoniae Klebsiella pneumoniae MIC 20.0 ug.mL-1 10.1016/j.ejmech.2011.12.012
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01451-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 48.0 ug.mL-1 10.1128/aac.01451-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 50.0 ug.mL-1 10.1016/s0960-894x(03)00547-x
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01284-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 100.0 ug.mL-1 10.1016/j.bmcl.2007.09.062
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1016/j.ejmech.2011.02.066
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1016/j.ejmech.2012.12.034
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00909-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1007/s00044-012-0011-4
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1016/j.bmcl.2016.03.098
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00436-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00543-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01180-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01284-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01451-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.00458-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.00461-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.01672-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2048.0 ug.mL-1 10.1128/aac.00017-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2048.0 ug.mL-1 10.1128/aac.01381-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4096.0 ug.mL-1 10.1128/aac.00387-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64000.0 nM 10.1128/aac.01381-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256000.0 ug.mL-1 10.1007/s00044-012-0202-z
Klebsiella pneumoniae Klebsiella pneumoniae MIC nan None 10.1128/aac.00657-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 16.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 100.0 ug.mL-1 10.1016/j.bmcl.2007.08.021
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1021/jm00021a013
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 256.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 100000.0 nM 10.1016/j.ejmech.2019.111615
Listeria innocua Listeria innocua MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Listeria monocytogenes Listeria monocytogenes Activity 75.0 % 10.1128/aac.00177-08
Listeria monocytogenes Listeria monocytogenes Activity nan None 10.1128/aac.00177-08
Listeria monocytogenes Listeria monocytogenes Activity nan None 10.1128/aac.01211-07
Listeria monocytogenes Listeria monocytogenes FC 1.0 None 10.1128/aac.00177-08
Listeria monocytogenes Listeria monocytogenes IZ 22.0 mm 10.1007/s00044-009-9214-8
Listeria monocytogenes Listeria monocytogenes IZ 22.0 mm 10.1007/s00044-012-0039-5
Listeria monocytogenes Listeria monocytogenes MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Listeria monocytogenes Listeria monocytogenes MIC 2000.0 nM 10.1016/j.ejmech.2017.01.038
Listeria monocytogenes Listeria monocytogenes MIC 4000.0 nM 10.1016/j.ejmech.2017.01.038
Listeria monocytogenes Listeria monocytogenes MIC90 0.5 ug.mL-1 10.1016/0960-894X(95)00072-2
Listeria monocytogenes Listeria monocytogenes MIC90 0.5 ug.mL-1 10.1021/jm00021a013
Listeria monocytogenes Listeria monocytogenes TIME 12.0 hr 10.1128/aac.00177-08
Mammaliicoccus sciuri Mammaliicoccus sciuri MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Micrococcus luteus Micrococcus luteus IZ 11.0 mm 10.1007/s00044-012-0011-4
Micrococcus luteus Micrococcus luteus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2011.02.066
Micrococcus luteus Micrococcus luteus MIC 1.0 ug.mL-1 10.1007/s00044-012-0011-4
Micrococcus luteus Micrococcus luteus MIC 1000.0 ug.mL-1 10.1007/s00044-012-0202-z
Moraxella catarrhalis Moraxella catarrhalis MIC 0.015 ug.mL-1 10.1128/aac.01326-07
Moraxella catarrhalis Moraxella catarrhalis MIC 0.06 ug.mL-1 10.1016/j.bmcl.2010.11.102
Moraxella catarrhalis Moraxella catarrhalis MIC 0.06 ug.mL-1 10.1016/j.ejmech.2014.07.106
Moraxella catarrhalis Moraxella catarrhalis MIC 0.39 ug.mL-1 10.1016/s0960-894x(98)00335-7
Moraxella catarrhalis Moraxella catarrhalis MIC 0.5 ug.mL-1 10.1016/j.bmc.2010.03.045
Moraxella catarrhalis Moraxella catarrhalis MIC50 1.0 ug.mL-1 10.1128/aac.01326-07
Moraxella catarrhalis Moraxella catarrhalis MIC90 2.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Moraxella catarrhalis Moraxella catarrhalis MIC90 2.0 ug.mL-1 10.1021/jm00021a013
Moraxella catarrhalis Moraxella catarrhalis MIC90 8.0 ug.mL-1 10.1128/aac.01326-07
Morganella morganii Morganella morganii MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Morganella morganii Morganella morganii MIC 100.0 ug.mL-1 10.1016/s0960-894x(03)00547-x
Morganella morganii Morganella morganii MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Mus musculus Monoamine oxidase A Activity nan None 10.1021/jm800656v
Mus musculus Monoamine oxidase B Activity nan None 10.1021/jm800656v
Mus musculus Mus musculus AUC 46000.0 ng.hr.mL-1 10.1128/aac.00004-06
Mus musculus Mus musculus AUC 80000.0 ng.hr.mL-1 10.1128/aac.00004-06
Mus musculus Mus musculus AUC 227000.0 ng.hr.mL-1 10.1128/aac.00004-06
Mus musculus Mus musculus AUC nan None 10.1021/jm020868v
Mus musculus Mus musculus CD50 0.24 mg kg-1 10.1021/jm950882q
Mus musculus Mus musculus CD50 0.28 mg kg-1 10.1021/jm950882q
Mus musculus Mus musculus Cmax 35576.48 nM 10.1128/aac.00004-06
Mus musculus Mus musculus Cmax 76626.26 nM 10.1128/aac.00004-06
Mus musculus Mus musculus Cmax 232615.42 nM 10.1128/aac.00004-06
Mus musculus Mus musculus Cmax nan None 10.1021/jm020868v
Mus musculus Mus musculus ED50 0.05 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.06 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.063 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.073 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.074 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.08 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.13 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.14 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.25 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.31 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus ED50 0.62 mg.kg-1 10.1021/jm00178a011
Mus musculus Mus musculus MBC 0.05 ug ml-1 10.1021/jm970165r
Mus musculus Mus musculus PD50 200.0 mg kg-1 10.1021/jm00144a034
Mus musculus Mus musculus PD50 800.0 mg kg-1 10.1021/jm00144a034
Mus musculus Mus musculus Survival 50.0 % 10.1128/aac.00004-06
Mus musculus Mus musculus Survival 57.0 % 10.1128/aac.00004-06
Mus musculus Mus musculus Survival 81.0 % 10.1128/aac.00004-06
Mus musculus Mus musculus Survival 82.0 % 10.1128/aac.00004-06
Mus musculus Mus musculus Survival 83.0 % 10.1128/aac.00004-06
Mus musculus Mus musculus T1/2 1.6 hr 10.1128/aac.00004-06
Mus musculus Mus musculus T1/2 1.7 hr 10.1128/aac.00004-06
Mus musculus Mus musculus Therapeutic efficacy 0.0 None 10.1016/s0960-894x(99)00549-1
Mus musculus Mus musculus Therapeutic efficacy 1.0 None 10.1016/s0960-894x(99)00549-1
Mus musculus Mus musculus Therapeutic efficacy 3.0 None 10.1016/s0960-894x(99)00549-1
Mus musculus Mus musculus Therapeutic efficacy 7.0 None 10.1016/s0960-894x(99)00549-1
Mus musculus Mus musculus T>MIC 4.0 hr 10.1128/aac.00004-06
Mus musculus Mus musculus T>MIC 8.0 hr 10.1128/aac.00004-06
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mycobacterium marinum Mycobacterium marinum Activity nan None 10.1016/j.bmc.2016.01.059
Mycobacterium tuberculosis Mycobacterium tuberculosis FC 1.5 None 10.1016/j.ejmech.2014.08.066
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.23 ug.mL-1 10.1016/j.ejmech.2014.08.066
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.32 ug.mL-1 10.1016/j.ejmech.2014.08.066
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 10.0 ug.mL-1 10.1016/j.ejmech.2017.06.005
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC 16100.0 nM 10.1021/jm031089x
Mycolicibacterium phlei Mycolicibacterium phlei DIZ nan None 10.1016/j.ejmech.2010.03.028
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 8.0 ug.mL-1 10.1016/j.ejmech.2016.12.060
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 7.7 ug.mL-1 10.1016/s0960-894x(98)00206-6
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 7.7 ug.mL-1 10.1021/jm000169n
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 7.7 ug.mL-1 10.1021/jm9900671
Neisseria meningitidis Neisseria meningitidis MIC 0.056 ug.mL-1 10.1016/s0960-894x(98)00206-6
Neisseria meningitidis Neisseria meningitidis MIC 0.056 ug.mL-1 10.1021/jm000169n
Neisseria meningitidis Neisseria meningitidis MIC 0.056 ug.mL-1 10.1021/jm9900671
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Paeniclostridium sordellii Paeniclostridium sordellii MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Parabacteroides distasonis Parabacteroides distasonis Activity 16.3 % 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC 0.125 ug.mL-1 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC 2.0 ug.mL-1 10.1128/aac.01557-08
Parabacteroides distasonis Parabacteroides distasonis MIC50 4.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC50 4.0 ug.mL-1 10.1128/aac.01557-08
Parabacteroides distasonis Parabacteroides distasonis MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC90 16.0 ug.mL-1 10.1128/aac.01557-08
Parabacteroides merdae Parabacteroides merdae Activity 19.6 % 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC 0.25 ug.mL-1 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Paraclostridium bifermentans Paraclostridium bifermentans MIC 0.25 ug.mL-1 10.1128/aac.01557-08
Parvimonas micra Parvimonas micra Activity 3.0 % 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra Activity 94.0 % 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Parvimonas micra Parvimonas micra MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Parvimonas micra Parvimonas micra MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra MIC90 0.5 ug.mL-1 10.1128/aac.01557-08
Parvimonas micra Parvimonas micra MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Pasteurella multocida Pasteurella multocida MIC 1.0 ug.mL-1 10.1128/aac.01522-08
Pasteurella multocida Pasteurella multocida MIC 256.0 ug.mL-1 10.1128/aac.01522-08
Pasteurella sp. Pasteurella sp. MIC 16.0 ug.mL-1 10.1016/j.ejmech.2012.12.034
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 3.0 % 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 94.0 % 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity 3.0 % 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity 94.0 % 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.125 ug.mL-1 10.1128/aac.00056-07
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.25 ug.mL-1 10.1128/aac.01557-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 0.38 ug.mL-1 10.1128/aac.00056-07
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 32.0 ug.mL-1 10.1128/aac.01557-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 21.3 % 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 30.0 % 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 53.0 % 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 0.25 ug.mL-1 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 0.5 ug.mL-1 10.1128/aac.01557-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 2.0 ug.mL-1 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 1.0 ug.mL-1 10.1128/aac.01557-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 8.0 ug.mL-1 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 8.0 ug.mL-1 10.1128/aac.01557-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 32.0 ug.mL-1 10.1128/aac.00355-08
Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Porphyromonas gingivalis Porphyromonas gingivalis MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Prescottella equi Prescottella equi MBC50 8.0 mg/L 10.1128/aac.00344-06
Prescottella equi Prescottella equi MBC90 32.0 mg/L 10.1128/aac.00344-06
Prescottella equi Prescottella equi MIC50 1.0 ug.mL-1 10.1128/aac.00344-06
Prescottella equi Prescottella equi MIC90 2.0 ug.mL-1 10.1128/aac.00344-06
Prevotella bivia Prevotella bivia Activity 6.0 % 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia Activity 81.0 % 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella bivia Prevotella bivia MIC50 0.5 ug.mL-1 10.1128/aac.01557-08
Prevotella bivia Prevotella bivia MIC50 4.0 ug.mL-1 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC90 4.0 ug.mL-1 10.1128/aac.01557-08
Prevotella bivia Prevotella bivia MIC90 16.0 ug.mL-1 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae Activity 6.0 % 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae Activity 81.0 % 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella buccae Prevotella buccae MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella buccae Prevotella buccae MIC50 4.0 ug.mL-1 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC90 1.0 ug.mL-1 10.1128/aac.01557-08
Prevotella buccae Prevotella buccae MIC90 16.0 ug.mL-1 10.1128/aac.00355-08
Prevotella corporis Prevotella corporis MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella corporis Prevotella corporis MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella denticola Prevotella denticola MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella denticola Prevotella denticola MIC50 0.25 ug.mL-1 10.1128/aac.01557-08
Prevotella denticola Prevotella denticola MIC90 2.0 ug.mL-1 10.1128/aac.01557-08
Prevotella disiens Prevotella disiens MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella disiens Prevotella disiens MIC50 0.25 ug.mL-1 10.1128/aac.01557-08
Prevotella intermedia Prevotella intermedia Activity 6.0 % 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia Activity 81.0 % 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella intermedia Prevotella intermedia MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella intermedia Prevotella intermedia MIC50 4.0 ug.mL-1 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia MIC90 0.5 ug.mL-1 10.1128/aac.01557-08
Prevotella intermedia Prevotella intermedia MIC90 16.0 ug.mL-1 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica Activity 6.0 % 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica Activity 81.0 % 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella melaninogenica Prevotella melaninogenica MIC50 0.25 ug.mL-1 10.1128/aac.01557-08
Prevotella melaninogenica Prevotella melaninogenica MIC50 4.0 ug.mL-1 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica MIC90 2.0 ug.mL-1 10.1128/aac.01557-08
Prevotella melaninogenica Prevotella melaninogenica MIC90 16.0 ug.mL-1 10.1128/aac.00355-08
Prevotella nigrescens Prevotella nigrescens MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella nigrescens Prevotella nigrescens MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
Prevotella nigrescens Prevotella nigrescens MIC90 0.5 ug.mL-1 10.1128/aac.01557-08
Priestia megaterium Priestia megaterium IZ 24.0 mm 10.1007/s00044-011-9857-0
Priestia megaterium Priestia megaterium MIC 2.28 ug.mL-1 10.1016/j.ejmech.2011.02.051
Priestia megaterium Priestia megaterium MIC 2.75 ug.mL-1 10.1016/j.ejmech.2010.09.049
Proteus Proteus IZ 17.0 mm 10.1007/s00044-009-9214-8
Proteus mirabilis Proteus mirabilis IZ 16.0 mm 10.1021/np970294a
Proteus mirabilis Proteus mirabilis MIC 0.4 ug.mL-1 10.1021/jm00178a011
Proteus mirabilis Proteus mirabilis MIC 128.0 ug.mL-1 10.1128/aac.00111-10
Proteus mirabilis Proteus mirabilis MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Proteus vulgaris Proteus vulgaris IZ 20.0 mm 10.1007/s00044-011-9857-0
Proteus vulgaris Proteus vulgaris IZ 24.0 mm 10.1016/j.bmcl.2015.07.071
Proteus vulgaris Proteus vulgaris MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.07.071
Proteus vulgaris Proteus vulgaris MIC 128.0 ug.mL-1 10.1016/j.ejmech.2012.12.034
Proteus vulgaris Proteus vulgaris MIC 256.0 ug.mL-1 10.1016/j.bmcl.2016.03.098
Proteus vulgaris Proteus vulgaris MIC 4000.0 nM 10.1021/jm031089x
Proteus vulgaris Proteus vulgaris MIC50 100.0 ug.mL-1 10.1016/j.bmcl.2007.08.021
Proteus vulgaris Proteus vulgaris MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Providencia rettgeri Providencia rettgeri MIC 256.0 ug.mL-1 10.1128/aac.01312-09
Providencia rettgeri Providencia rettgeri MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Providencia stuartii Providencia stuartii MIC 2048.0 ug.mL-1 10.1128/aac.00017-09
Providencia stuartii Providencia stuartii MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Pseudomonas aeruginosa Beta-lactamase Kcat 2.5 /s 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase Kcat/Km 80.0 /uM/s 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase Km 30000.0 nM 10.1128/aac.01410-08
Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition 10.8 % 10.6019/CHEMBL4513141
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 6.0 mm 10.1016/j.ejmech.2017.11.001
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 7.5 mm 10.1007/s00044-012-0011-4
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 10.0 mm 10.1007/s00044-007-9017-8
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 10.0 mm 10.1016/j.ejmech.2020.112832
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 11.0 mm 10.1016/j.ejmech.2020.113034
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 12.0 mm 10.1016/j.ejmech.2010.03.028
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 15.0 mm 10.1007/s00044-010-9440-0
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 15.0 mm 10.1021/np970294a
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 15.0 mm 10.1039/d2md00076h
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 16.0 mm 10.1021/np0497447
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 19.0 mm 10.1007/s00044-012-0032-z
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 20.0 mm 10.1016/j.ejmech.2009.02.020
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 20.0 mm 10.1016/j.ejmech.2009.09.002
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 21.0 mm 10.1007/s00044-011-9634-0
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 21.0 mm 10.1016/j.bmcl.2015.07.071
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 21.0 mm 10.1016/j.ejmech.2019.111744
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 21.4 mm 10.1016/j.ejmech.2014.03.037
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 24.0 mm 10.1016/j.ejmech.2017.05.010
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 25.0 mm 10.1016/j.ejmech.2019.111744
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 26.0 mm 10.1007/s00044-009-9184-x
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 27.0 mm 10.1007/s00044-010-9440-0
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 30.0 mm 10.1007/s00044-010-9354-x
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 100.0 mg/L 10.1007/s00044-011-9933-5
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.01451-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.3 ug.mL-1 10.1007/s00044-011-9733-y
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.39 ug.mL-1 10.1016/j.ejmech.2015.03.021
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2012.08.084
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.ejmech.2017.05.010
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2012.09.083
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.07.071
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1007/s00044-010-9354-x
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1007/s00044-011-9634-0
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 10.0 ug.mL-1 10.1016/j.ejmech.2022.114502
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 14.53 ug.mL-1 10.1016/j.ejmech.2010.09.049
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 14.67 ug.mL-1 10.1016/j.ejmech.2011.02.051
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.ejmech.2012.12.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.ejmech.2010.03.028
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.ejmech.2011.04.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 100.0 ug.mL-1 10.1021/jm00178a011
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 200.0 ug.mL-1 10.1007/s00044-012-0270-0
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 200.0 ug.mL-1 10.1016/j.ejmech.2007.01.022
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1007/s00044-012-0011-4
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1016/j.ejmech.2011.02.066
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.01451-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1016/j.bmcl.2016.03.098
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1128/aac.00033-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1128/aac.00175-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1128/aac.00859-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4300.0 nM 10.1039/d1md00091h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64000.0 nM 10.1021/acsmedchemlett.1c00683
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 100000.0 nM 10.1021/acs.jmedchem.9b00370
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 100000.0 nM 10.1021/acs.jnatprod.5b01129
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256000.0 ug.mL-1 10.1007/s00044-012-0202-z
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1128/aac.01561-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 3.2 ug.mL-1 10.1007/s00044-011-9634-0
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 390.0 nM 10.1016/j.ejmech.2019.111615
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 460.0 nM 10.1016/j.ejmech.2019.111615
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 100000.0 nM 10.1016/j.ejmech.2019.111615
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 200000.0 nM 10.1016/j.ejmech.2019.111615
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio 1.0 None 10.1016/j.ejmech.2009.09.002
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat 0.5 /s 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat/Km 25.0 /uM/s 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Km 20000.0 nM 10.1128/aac.01410-08
Pseudomonas fluorescens Pseudomonas fluorescens MIC 256.0 ug.mL-1 10.1128/aac.00961-09
Pseudomonas luteola Beta-lactamase Kcat 21.0 /s 10.1128/aac.00427-09
Pseudomonas luteola Beta-lactamase Kcat/Km 1.05 /s/microM 10.1128/aac.00427-09
Pseudomonas luteola Beta-lactamase Km 20000.0 nM 10.1128/aac.00427-09
Pseudomonas putida Pseudomonas putida IZ 15.0 mm 10.1007/s00044-009-9214-8
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Bile salt export pump IC50 1000000.0 nM 10.1124/dmd.111.040758
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Oligopeptide transporter, kidney isoform Ki 179000.0 nM 10.1152/ajprenal.1997.273.5.f706
Rattus norvegicus Oligopeptide transporter, kidney isoform Ki 430000.0 nM 10.1016/j.ejpb.2004.07.008
Rattus norvegicus Plasma Fu 0.85 None 10.1021/jm901371v
Rattus norvegicus Plasma logFu 0.82 None 10.1016/j.ejmech.2009.06.004
Rattus norvegicus Rattus norvegicus ALB 40700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 42300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 44000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 44300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 350.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 365.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 400.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 414.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 419.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 434.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 47.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 49.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 49.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 52.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 59.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 61.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 77.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 82.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 83.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 85.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 89.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 94.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 153.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 160.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 163.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 170.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 173.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 190.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 101.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 643.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 750.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 760.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 763.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 796.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 963.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 343.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 363.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 366.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 449.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 622.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 777.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Cmax 80457.57 nM 10.1128/aac.00744-06
Rattus norvegicus Rattus norvegicus Cmin 0.52 mg/L 10.1128/aac.00744-06
Rattus norvegicus Rattus norvegicus CO2 31330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 31830000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 32000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 32330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 33000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 35000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 25.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 109.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Gastric concentration 6.0 ug g-1 10.1016/j.bmcl.2004.02.068
Rattus norvegicus Rattus norvegicus Gastric concentration 12.0 ug g-1 10.1016/j.bmcl.2004.02.068
Rattus norvegicus Rattus norvegicus Gastric concentration 33.0 ug g-1 10.1016/j.bmcl.2004.02.068
Rattus norvegicus Rattus norvegicus Gastric concentration nan None 10.1016/j.bmcl.2004.02.068
Rattus norvegicus Rattus norvegicus GLUC 1130.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1336.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1380.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1460.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1583.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1735.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 34.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 35.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 37.2 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 37.62 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 38.03 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 39.43 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 131700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 132800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 138700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 140000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 141000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 144700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Inhibition nan % 10.1021/jm010217j
Rattus norvegicus Rattus norvegicus LDH 112.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 129.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 129.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 161.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 163.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 186.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 6222.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 7076.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 8994.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13682.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 14357.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 14631.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 88.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 90.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 90.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 92.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.15 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.5 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.53 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.68 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.87 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 367000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 368000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 368800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 378000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 379000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 385300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.27 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.87 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.93 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.87 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.03 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.23 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 76.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 122.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 124.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 211.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 456.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 492.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 3.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 5.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 6.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 6.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 7.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 9.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 448.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 487.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 666.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 914.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 958.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1461.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 102.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 110.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 115.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 119.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 124.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 129.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1117000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1125330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1145670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1169670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1311330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1509330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.73 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.75 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.14 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.77 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 7.01 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 7.23 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 56700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 63700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 64300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5520000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5740000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5850000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5960000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6010000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6160000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Recovery rate nan None 10.1016/j.bmcl.2004.02.068
Rattus norvegicus Rattus norvegicus SODIUM 141.53 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.1 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.9 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.85 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 144.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Tmax 2.0 hr 10.1128/aac.00744-06
Rattus norvegicus Rattus norvegicus T>MIC 12.0 hr 10.1128/aac.00744-06
Rattus norvegicus Rattus norvegicus URATE 7.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 8.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 9.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 17.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 20.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 21.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 6830.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 7600.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 9780.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 15130.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 15870.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 16300.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Solute carrier family 15 member 1 Ki 13000000.0 nM 10.1152/ajprenal.1997.273.5.f706
Rattus norvegicus Solute carrier family 22 member 6 Activity nan None None
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Voltage-gated N-type calcium channel alpha-1B subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Salmonella Salmonella MIC 128.0 ug.mL-1 10.1016/j.ejmech.2012.12.034
Salmonella enterica subsp. enterica Salmonella enterica subsp. enterica IZ 17.2 mm 10.1016/j.ejmech.2008.09.004
Salmonella enterica subsp. enterica Salmonella enterica subsp. enterica MIC 32.0 ug.mL-1 10.1016/j.ejmech.2008.09.004
Salmonella enterica subsp. enterica serovar Gallinarum Salmonella enterica subsp. enterica serovar Gallinarum MIC 2.0 ug.mL-1 10.1007/s00044-011-9755-5
Salmonella enterica subsp. enterica serovar Paratyphi A Salmonella paratyphi IZ 22.0 mm 10.1016/j.bmcl.2015.07.071
Salmonella enterica subsp. enterica serovar Paratyphi A Salmonella paratyphi MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.07.071
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi IZ 12.0 mm 10.1016/j.ejmech.2010.08.005
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi IZ 12.0 mm 10.1021/np970294a
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi IZ 18.0 mm 10.1007/s00044-012-0032-z
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi IZ 19.0 mm 10.1007/s00044-012-0039-5
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi IZ 20.5 mm 10.1016/j.ejmech.2010.08.005
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi IZ 21.0 mm 10.1016/j.bmcl.2015.07.071
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 0.2 ug.mL-1 10.1007/s00044-011-9733-y
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 0.5 ug.mL-1 10.1016/j.bmcl.2015.07.071
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 0.9 ug.mL-1 10.1016/j.bmcl.2012.08.084
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 128.0 ug.mL-1 10.1016/j.ejmech.2011.02.066
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IC50 1.85 ug.mL-1 10.1016/j.ejmech.2007.12.008
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 17.2 mm 10.1007/s00044-012-0155-2
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 17.2 mm 10.1016/j.ejmech.2007.12.008
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 19.0 mm 10.1007/s00044-009-9214-8
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 21.82 mm 10.1016/j.ejmech.2011.04.013
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 25.2 mm 10.1016/j.ejmech.2007.12.004
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 25.2 mm 10.1016/j.ejmech.2008.06.008
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 3.12 ug.mL-1 10.1016/j.ejmech.2007.12.008
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 32.0 ug.mL-1 10.1007/s00044-012-0155-2
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 32.0 ug.mL-1 10.1016/j.ejmech.2007.12.004
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 32.0 ug.mL-1 10.1016/j.ejmech.2008.06.008
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 32.0 ug.mL-1 10.1016/j.ejmech.2011.04.013
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 1000.0 ug.mL-1 10.1016/j.ejmech.2011.02.066
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC nan None 10.1128/aac.01472-06
Salmonella enterica subsp. enterica serovar Westhampton Extended-spectrum beta-lactamase CTX-M-53 Kcat 85.0 /s 10.1128/aac.01581-08
Salmonella enterica subsp. enterica serovar Westhampton Extended-spectrum beta-lactamase CTX-M-53 Kcat/Km 2.1 /s/microM 10.1128/aac.01581-08
Salmonella enterica subsp. enterica serovar Westhampton Extended-spectrum beta-lactamase CTX-M-53 Km 40000.0 nM 10.1128/aac.01581-08
Serratia marcescens Serratia marcescens IZ 6.0 mm 10.1016/j.ejmech.2017.11.001
Serratia marcescens Serratia marcescens MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Serratia marcescens Serratia marcescens MIC 64.0 ug.mL-1 10.1128/aac.01028-07
Serratia marcescens Serratia marcescens MIC 100.0 ug.mL-1 10.1016/s0960-894x(98)00335-7
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 11.63 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -0.02 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 1.48 % 10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition index 0.1371 None 10.1101/2020.04.03.023846
Shigella boydii Shigella boydii IZ 14.0 mm 10.1007/s00044-009-9214-8
Shigella boydii Shigella boydii IZ 17.0 mm 10.1021/np970294a
Shigella boydii Shigella boydii IZ 19.0 mm 10.1007/s00044-009-9214-8
Shigella boydii Shigella boydii IZ 24.0 mm 10.1007/s00044-009-9214-8
Shigella dysenteriae Shigella dysenteriae IZ 9.5 mm 10.1007/s00044-012-0011-4
Shigella dysenteriae Shigella dysenteriae MIC 64.0 ug.mL-1 10.1016/j.ejmech.2011.02.066
Shigella dysenteriae Shigella dysenteriae MIC 100.0 ug.mL-1 10.1007/s00044-012-0011-4
Shigella dysenteriae Shigella dysenteriae MIC 10000.0 ug.mL-1 10.1007/s00044-012-0202-z
Shigella flexneri Shigella flexneri MIC 128.0 ug.mL-1 10.1016/j.ejmech.2011.02.066
Shigella sonnei Shigella sonnei MIC 1.0 ug.mL-1 10.1128/aac.00227-08
Shigella sonnei Shigella sonnei MIC 2.0 ug.mL-1 10.1128/aac.00227-08
Shouchella clausii Shouchella clausii MIC 120.0 ug.mL-1 10.1128/aac.00537-07
Shouchella clausii Shouchella clausii MIC 500.0 ug.mL-1 10.1128/aac.00537-07
Shouchella clausii Shouchella clausii MIC 1000.0 ug.mL-1 10.1128/aac.00537-07
Siminovitchia fortis Siminovitchia fortis MIC 2.0 ug.mL-1 10.1007/s00044-011-9755-5
Staphylococcus Staphylococcus IZ 7.0 mm 10.1016/j.ejmech.2010.12.005
Staphylococcus Staphylococcus MIC 23.0 ug.mL-1 10.1016/j.ejmech.2010.12.005
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/jm0703183
Staphylococcus aureus Staphylococcus aureus Antibiotic resistance nan None 10.1016/s0960-894x(98)00536-8
Staphylococcus aureus Staphylococcus aureus EC50 150.0 nM 10.1016/j.ejmech.2022.114502
Staphylococcus aureus Staphylococcus aureus ED50 50.0 mg.kg-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus FC 2.6 None 10.1128/aac.00457-09
Staphylococcus aureus Staphylococcus aureus IC50 1.82 ug.mL-1 10.1016/j.ejmech.2007.12.008
Staphylococcus aureus Staphylococcus aureus IC50 2.84 ug.mL-1 10.1016/j.bmcl.2012.09.083
Staphylococcus aureus Staphylococcus aureus Inhibition 15.09 % 10.6019/CHEMBL4513141
Staphylococcus aureus Staphylococcus aureus IZ 0.0 mm 10.1016/j.ejmech.2017.11.001
Staphylococcus aureus Staphylococcus aureus IZ 8.0 mm 10.1016/j.ejmech.2011.12.012
Staphylococcus aureus Staphylococcus aureus IZ 10.5 mm 10.1007/s00044-012-0011-4
Staphylococcus aureus Staphylococcus aureus IZ 12.5 mm 10.1016/j.ejmech.2010.08.005
Staphylococcus aureus Staphylococcus aureus IZ 13.0 mm 10.1007/s00044-010-9440-0
Staphylococcus aureus Staphylococcus aureus IZ 13.0 mm 10.1016/j.ejmech.2010.03.028
Staphylococcus aureus Staphylococcus aureus IZ 13.8 mm 10.1039/d2md00076h
Staphylococcus aureus Staphylococcus aureus IZ 16.0 mm 10.1021/np0497447
Staphylococcus aureus Staphylococcus aureus IZ 16.0 mm 10.1021/np970294a
Staphylococcus aureus Staphylococcus aureus IZ 16.5 mm 10.1016/j.ejmech.2010.08.005
Staphylococcus aureus Staphylococcus aureus IZ 16.6 mm 10.1007/s00044-012-0084-0
Staphylococcus aureus Staphylococcus aureus IZ 17.0 mm 10.1007/s00044-012-0155-2
Staphylococcus aureus Staphylococcus aureus IZ 17.0 mm 10.1016/j.ejmech.2007.12.008
Staphylococcus aureus Staphylococcus aureus IZ 17.0 mm 10.1016/j.ejmech.2008.09.004
Staphylococcus aureus Staphylococcus aureus IZ 17.3 mm 10.1007/s00044-012-0084-0
Staphylococcus aureus Staphylococcus aureus IZ 17.5 mm 10.1039/d2md00076h
Staphylococcus aureus Staphylococcus aureus IZ 17.6 mm 10.1016/j.bmc.2019.02.044
Staphylococcus aureus Staphylococcus aureus IZ 20.0 mm 10.1016/j.ejmech.2008.09.029
Staphylococcus aureus Staphylococcus aureus IZ 20.85 mm 10.1016/j.ejmech.2011.04.013
Staphylococcus aureus Staphylococcus aureus IZ 21.0 mm 10.1007/s00044-012-0032-z
Staphylococcus aureus Staphylococcus aureus IZ 21.0 mm 10.1016/j.ejmech.2007.12.004
Staphylococcus aureus Staphylococcus aureus IZ 21.0 mm 10.1016/j.ejmech.2008.06.008
Staphylococcus aureus Staphylococcus aureus IZ 21.0 mm 10.1016/j.ejmech.2019.111744
Staphylococcus aureus Staphylococcus aureus IZ 22.0 mm 10.1007/s00044-011-9857-0
Staphylococcus aureus Staphylococcus aureus IZ 22.0 mm 10.1016/j.ejmech.2014.03.037
Staphylococcus aureus Staphylococcus aureus IZ 24.0 mm 10.1007/s00044-010-9440-0
Staphylococcus aureus Staphylococcus aureus IZ 25.0 mm 10.1007/s00044-007-9017-8
Staphylococcus aureus Staphylococcus aureus IZ 25.0 mm 10.1016/j.ejmech.2017.05.010
Staphylococcus aureus Staphylococcus aureus IZ 25.0 mm 10.1016/j.ejmech.2019.111744
Staphylococcus aureus Staphylococcus aureus IZ 29.0 mm 10.1007/s00044-010-9354-x
Staphylococcus aureus Staphylococcus aureus IZ 29.0 mm 10.1016/j.ejmech.2020.113034
Staphylococcus aureus Staphylococcus aureus IZ 30.0 mm 10.1007/s00044-009-9184-x
Staphylococcus aureus Staphylococcus aureus IZ 30.0 mm 10.1007/s00044-009-9214-8
Staphylococcus aureus Staphylococcus aureus IZ 30.0 mm 10.1007/s00044-011-9634-0
Staphylococcus aureus Staphylococcus aureus IZ 30.0 mm 10.1007/s00044-012-0039-5
Staphylococcus aureus Staphylococcus aureus IZ 30.0 mm 10.1016/j.ejmech.2009.02.020
Staphylococcus aureus Staphylococcus aureus IZ 30.0 mm 10.1016/j.ejmech.2009.09.002
Staphylococcus aureus Staphylococcus aureus IZ 30.0 mm 10.1016/j.ejmech.2020.112832
Staphylococcus aureus Staphylococcus aureus IZ 32.0 mm 10.1016/j.bmcl.2015.07.071
Staphylococcus aureus Staphylococcus aureus MBC 2.5 uM 10.1016/j.bmc.2020.115974
Staphylococcus aureus Staphylococcus aureus MBC 4.0 mg/L 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus MBC 85.6 uM 10.1016/j.bmcl.2020.127234
Staphylococcus aureus Staphylococcus aureus MBC 85.7 uM 10.1016/j.bmc.2020.115974
Staphylococcus aureus Staphylococcus aureus MBC 94.4 uM 10.1016/j.bmcl.2020.127234
Staphylococcus aureus Staphylococcus aureus MBC 100.0 mg/L 10.1007/s00044-011-9933-5
Staphylococcus aureus Staphylococcus aureus MBC50 8.0 mg/L 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MBC50 64.0 mg/L 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MBC90 16.0 mg/L 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MBC90 256.0 mg/L 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MIC 0.05 ug.mL-1 10.1016/j.bmc.2021.116580
Staphylococcus aureus Staphylococcus aureus MIC 0.05 ug.mL-1 10.1016/j.bmcl.2015.06.010
Staphylococcus aureus Staphylococcus aureus MIC 0.05 ug.mL-1 10.1016/s0960-894x(98)00335-7
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2016.03.098
Staphylococcus aureus Staphylococcus aureus MIC 0.1 ug.mL-1 10.1016/j.bmc.2017.05.037
Staphylococcus aureus Staphylococcus aureus MIC 0.1 ug.mL-1 10.1016/j.bmc.2021.116580
Staphylococcus aureus Staphylococcus aureus MIC 0.1 ug.mL-1 10.1021/jm00178a011
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/j.bmcl.2010.11.102
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/j.bmcl.2012.08.021
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1021/jm025502x
Staphylococcus aureus Staphylococcus aureus MIC 0.195 ug.mL-1 10.1016/j.bmcl.2007.09.062
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1007/s00044-011-9733-y
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1016/s0960-894x(03)00547-x
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmc.2017.05.037
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2010.05.110
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/jm950882q
Staphylococcus aureus Staphylococcus aureus MIC 0.29 ug.mL-1 10.1016/j.ejmech.2022.114502
Staphylococcus aureus Staphylococcus aureus MIC 0.39 ug.mL-1 10.1016/j.ejmech.2015.03.021
Staphylococcus aureus Staphylococcus aureus MIC 0.4 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 0.42 ug.mL-1 10.1016/j.bmc.2021.116580
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1007/s00044-012-0011-4
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2012.08.084
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2015.07.071
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2011.02.066
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus MIC 0.78 ug.mL-1 10.1039/C8MD00212F
Staphylococcus aureus Staphylococcus aureus MIC 0.8 ug.mL-1 10.1021/acs.jnatprod.5b00008
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmc.2010.03.045
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2012.08.021
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2011.04.034
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.7b00108
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 1.5 ug.mL-1 10.1016/j.ejmech.2017.05.010
Staphylococcus aureus Staphylococcus aureus MIC 1.56 ug.mL-1 10.1016/j.ejmech.2007.01.022
Staphylococcus aureus Staphylococcus aureus MIC 1.6 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2012.08.021
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2018.11.052
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01247-08
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus MIC 3.0 ug.mL-1 10.1021/acs.jnatprod.1c00222
Staphylococcus aureus Staphylococcus aureus MIC 3.12 ug.mL-1 10.1007/s00044-011-9634-0
Staphylococcus aureus Staphylococcus aureus MIC 3.12 ug.mL-1 10.1016/j.ejmech.2007.12.008
Staphylococcus aureus Staphylococcus aureus MIC 3.2 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2012.08.021
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1007/s00044-010-9354-x
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.bmcl.2012.08.021
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.bmcl.2016.03.098
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.ejmech.2018.11.052
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1007/s00044-012-0270-0
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1016/j.bmcl.2007.09.062
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1128/aac.00457-09
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 12.92 ug.mL-1 10.1016/j.ejmech.2011.02.051
Staphylococcus aureus Staphylococcus aureus MIC 13.32 ug.mL-1 10.1016/j.ejmech.2010.09.049
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.ejmech.2010.03.028
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 23.0 ug.mL-1 10.1016/j.ejmech.2011.12.012
Staphylococcus aureus Staphylococcus aureus MIC 25.0 ug.mL-1 10.1016/j.ejmech.2012.12.034
Staphylococcus aureus Staphylococcus aureus MIC 31.3 ug.mL-1 10.1039/d2md00076h
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1007/s00044-012-0155-2
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2010.05.110
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2012.09.083
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2007.12.004
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2008.06.008
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2008.09.004
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2011.04.013
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2018.11.052
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/jm00382a025
Staphylococcus aureus Staphylococcus aureus MIC 50.0 ug.mL-1 10.1016/j.ejmech.2009.09.002
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2018.11.052
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/jm025502x
Staphylococcus aureus Staphylococcus aureus MIC 100.0 ug.mL-1 10.1021/jm00178a011
Staphylococcus aureus Staphylococcus aureus MIC 125.0 ug.mL-1 10.1021/jm00144a034
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1016/j.bmc.2017.05.037
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1016/j.ejmech.2018.11.052
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.7b00108
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus MIC 200.0 nM 10.1021/acs.jnatprod.5b00206
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1016/j.ejmech.2018.11.052
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1016/S0960-894X(00)80358-3
Staphylococcus aureus Staphylococcus aureus MIC 300.0 nM 10.1016/j.bmcl.2015.11.084
Staphylococcus aureus Staphylococcus aureus MIC 300.0 nM 10.1021/acs.jnatprod.5b00206
Staphylococcus aureus Staphylococcus aureus MIC 490.0 nM 10.1021/jm031089x
Staphylococcus aureus Staphylococcus aureus MIC 500.0 ug.mL-1 10.1007/s00044-012-0202-z
Staphylococcus aureus Staphylococcus aureus MIC 512.0 ug.mL-1 10.1016/j.ejmech.2018.11.052
Staphylococcus aureus Staphylococcus aureus MIC 700.0 nM 10.1016/j.bmc.2007.05.028
Staphylococcus aureus Staphylococcus aureus MIC 700.0 nM 10.1016/j.bmc.2020.115974
Staphylococcus aureus Staphylococcus aureus MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Staphylococcus aureus Staphylococcus aureus MIC 1000.0 nM 10.1021/acsmedchemlett.1c00683
Staphylococcus aureus Staphylococcus aureus MIC 1024.0 ug.mL-1 10.1016/j.ejmech.2018.11.052
Staphylococcus aureus Staphylococcus aureus MIC 1200.0 nM 10.1039/d1md00091h
Staphylococcus aureus Staphylococcus aureus MIC 3500.0 nM 10.1021/acs.jnatprod.5b01129
Staphylococcus aureus Staphylococcus aureus MIC 4000.0 nM 10.1021/acsmedchemlett.3c00093
Staphylococcus aureus Staphylococcus aureus MIC 6800.0 nM 10.1039/d1md00091h
Staphylococcus aureus Staphylococcus aureus MIC 16100.0 nM 10.1021/acs.jmedchem.8b00233
Staphylococcus aureus Staphylococcus aureus MIC 16100.0 nM 10.1021/jm031089x
Staphylococcus aureus Staphylococcus aureus MIC 17000.0 nM 10.1021/acs.jnatprod.5b01129
Staphylococcus aureus Staphylococcus aureus MIC 35000.0 nM 10.1021/acs.jnatprod.5b01129
Staphylococcus aureus Staphylococcus aureus MIC 50000.0 nM 10.1039/d1md00091h
Staphylococcus aureus Staphylococcus aureus MIC 64000.0 nM 10.1021/acsmedchemlett.1c00683
Staphylococcus aureus Staphylococcus aureus MIC 85600.0 nM 10.1016/j.bmcl.2020.127234
Staphylococcus aureus Staphylococcus aureus MIC 85700.0 nM 10.1016/j.bmc.2020.115974
Staphylococcus aureus Staphylococcus aureus MIC 94400.0 nM 10.1016/j.bmcl.2020.127234
Staphylococcus aureus Staphylococcus aureus MIC 125000.0 nM 10.1016/j.ejmech.2008.02.021
Staphylococcus aureus Staphylococcus aureus MIC 175000.0 nM 10.1021/acs.jmedchem.1c01482
Staphylococcus aureus Staphylococcus aureus MIC 175000.0 nM 10.1021/acs.jnatprod.5b00206
Staphylococcus aureus Staphylococcus aureus MIC 250000.0 nM 10.1016/j.ejmech.2008.02.021
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1128/aac.00457-09
Staphylococcus aureus Staphylococcus aureus MIC50 1.0 ug.mL-1 10.1021/jm0580510
Staphylococcus aureus Staphylococcus aureus MIC50 1.0 ug.mL-1 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MIC50 1.62 ug.mL-1 10.1007/s00044-011-9634-0
Staphylococcus aureus Staphylococcus aureus MIC50 32.0 ug.mL-1 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MIC50 64.0 ug.mL-1 10.1021/jm0580510
Staphylococcus aureus Staphylococcus aureus MIC50 100.0 ug.mL-1 10.1016/j.bmcl.2007.08.021
Staphylococcus aureus Staphylococcus aureus MIC90 1.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Staphylococcus aureus Staphylococcus aureus MIC90 1.0 ug.mL-1 10.1021/jm00021a013
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1021/jm0580510
Staphylococcus aureus Staphylococcus aureus MIC90 16.0 ug.mL-1 10.1021/jm025502x
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1021/jm00021a013
Staphylococcus aureus Staphylococcus aureus MIC90 128.0 ug.mL-1 10.1021/jm0580510
Staphylococcus aureus Staphylococcus aureus MIC90 128.0 ug.mL-1 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus Ratio 1.0 None 10.1016/j.ejmech.2009.09.002
Staphylococcus epidermidis Staphylococcus epidermidis IZ 2.0 mm 10.1016/j.ejmech.2017.11.001
Staphylococcus epidermidis Staphylococcus epidermidis IZ 13.0 mm 10.1007/s00044-012-0084-0
Staphylococcus epidermidis Staphylococcus epidermidis IZ 16.0 mm 10.1021/np0497447
Staphylococcus epidermidis Staphylococcus epidermidis IZ 16.6 mm 10.1007/s00044-012-0084-0
Staphylococcus epidermidis Staphylococcus epidermidis MBC 100.0 mg/L 10.1007/s00044-011-9933-5
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.125 ug.mL-1 10.1016/j.bmcl.2012.08.021
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.195 ug.mL-1 10.1016/j.bmcl.2007.09.062
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.78 ug.mL-1 10.1016/s0960-894x(03)00547-x
Staphylococcus epidermidis Staphylococcus epidermidis MIC 8.0 ug.mL-1 10.1016/j.bmcl.2012.08.021
Staphylococcus epidermidis Staphylococcus epidermidis MIC 100.0 ug.mL-1 10.1007/s00044-012-0270-0
Staphylococcus epidermidis Staphylococcus epidermidis MIC 128.0 ug.mL-1 10.1016/j.bmc.2017.05.037
Staphylococcus epidermidis Staphylococcus epidermidis MIC 200.0 nM 10.1021/acs.jnatprod.5b00206
Staphylococcus epidermidis Staphylococcus epidermidis MIC 35000.0 nM 10.1021/acs.jnatprod.5b01129
Staphylococcus epidermidis Staphylococcus epidermidis MIC 125000.0 nM 10.1016/j.ejmech.2008.02.021
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 1.0 ug.mL-1 10.1021/jm0580510
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 4.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 4.0 ug.mL-1 10.1021/jm00021a013
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 4.0 ug.mL-1 10.1021/jm0580510
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 8.0 ug.mL-1 10.1021/jm025502x
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 200.0 nM 10.1021/acs.jnatprod.5b00206
Staphylococcus intermedius Staphylococcus intermedius MIC 88000.0 nM 10.1021/acs.jnatprod.5b00206
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Staphylococcus saprophyticus Staphylococcus saprophyticus MBC 100.0 mg/L 10.1007/s00044-011-9933-5
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 700.0 nM 10.1021/acs.jnatprod.5b00206
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 nan ug.mL-1 10.1016/0960-894X(95)00072-2
Streptococcus agalactiae Streptococcus agalactiae MIC 0.031 ug.mL-1 10.1128/aac.01716-08
Streptococcus agalactiae Streptococcus agalactiae MIC 200.0 nM 10.1021/acs.jnatprod.5b00206
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.063 ug.mL-1 10.1128/aac.01716-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.06 ug.mL-1 10.1016/0960-894X(95)00072-2
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.06 ug.mL-1 10.1021/jm00021a013
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.125 ug.mL-1 10.1128/aac.01716-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1e-06 log10CFU/ml 10.1128/aac.00405-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.2 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.5 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 2.0 None 10.1128/aac.00405-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 5.0 None 10.1128/aac.00405-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 5.2 log10CFU/ml 10.1016/j.bmcl.2019.05.028
Streptococcus pneumoniae Streptococcus pneumoniae Activity 6.3 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 8.1 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 10.1 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 13.3 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 28.4 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 30.6 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 33.2 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 37.9 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 39.1 % 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 39.7 % 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 40.9 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 45.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 48.2 % 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 53.4 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 55.0 % 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 62.2 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 62.7 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 66.7 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 66.7 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 73.7 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 93.1 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 94.8 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 98.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 98.8 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.5 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 2.0 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 2.3 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 2.8 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 3.0 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 3.1 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 3.3 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 3.5 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 3.7 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 3.9 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 4.2 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 4.3 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 4.4 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 4.8 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 5.0 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 5.4 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 5.6 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 6.0 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 6.3 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml 7.2 None 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.023 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/j.bmcl.2019.05.028
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1021/jm00178a011
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00026-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.032 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.047 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2010.05.110
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2010.11.102
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.ejmech.2014.07.106
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.094 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.1 ug.mL-1 10.1128/aac.00405-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.19 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.75 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.5 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00004-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 3.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmc.2010.03.045
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00026-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 5.0 ug.mL-1 10.1128/aac.00405-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 7.8 ug.mL-1 10.1039/d2md00076h
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00405-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 500.0 nM 10.1021/acsmedchemlett.1c00683
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.016 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1021/jm0580510
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC80 2.0 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.015 ug.mL-1 10.1016/0960-894X(95)00072-2
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.015 ug.mL-1 10.1021/jm00021a013
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.12 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.12 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 3.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1021/jm0580510
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 35.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 47.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 48.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 62.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 97.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 100.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae R6 Penicillin-binding protein 2X Activity nan None 10.1021/jm900625q
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.004 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.017 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.044 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.049 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.059 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.067 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.09 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.124 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.422 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.029 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.03 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.033 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.05 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.055 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.144 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.165 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.176 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.22 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x Activity nan None 10.1021/jm900625q
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.004 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.008 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.018 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.022 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.037 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.043 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.062 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.094 ug.mL-1 10.1128/aac.01566-08
Streptococcus pyogenes Streptococcus pyogenes IC50 1.8 ug.mL-1 10.1016/j.ejmech.2007.12.008
Streptococcus pyogenes Streptococcus pyogenes IZ 0.0 mm 10.1016/j.ejmech.2017.11.001
Streptococcus pyogenes Streptococcus pyogenes IZ 16.0 mm 10.1021/np970294a
Streptococcus pyogenes Streptococcus pyogenes IZ 18.2 mm 10.1007/s00044-012-0155-2
Streptococcus pyogenes Streptococcus pyogenes IZ 18.2 mm 10.1016/j.ejmech.2007.12.008
Streptococcus pyogenes Streptococcus pyogenes IZ 18.2 mm 10.1016/j.ejmech.2008.09.004
Streptococcus pyogenes Streptococcus pyogenes IZ 19.57 mm 10.1016/j.ejmech.2011.04.013
Streptococcus pyogenes Streptococcus pyogenes IZ 22.2 mm 10.1016/j.ejmech.2007.12.004
Streptococcus pyogenes Streptococcus pyogenes IZ 22.2 mm 10.1016/j.ejmech.2008.06.008
Streptococcus pyogenes Streptococcus pyogenes MBC50 4.0 mg/L 10.1128/aac.00344-06
Streptococcus pyogenes Streptococcus pyogenes MBC90 8.0 mg/L 10.1128/aac.00344-06
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1021/jm00178a011
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1016/j.bmcl.2010.11.102
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1016/j.ejmech.2014.07.106
Streptococcus pyogenes Streptococcus pyogenes MIC 3.12 ug.mL-1 10.1016/j.ejmech.2007.12.008
Streptococcus pyogenes Streptococcus pyogenes MIC 32.0 ug.mL-1 10.1007/s00044-012-0155-2
Streptococcus pyogenes Streptococcus pyogenes MIC 32.0 ug.mL-1 10.1016/j.ejmech.2007.12.004
Streptococcus pyogenes Streptococcus pyogenes MIC 32.0 ug.mL-1 10.1016/j.ejmech.2008.06.008
Streptococcus pyogenes Streptococcus pyogenes MIC 32.0 ug.mL-1 10.1016/j.ejmech.2008.09.004
Streptococcus pyogenes Streptococcus pyogenes MIC 32.0 ug.mL-1 10.1016/j.ejmech.2011.04.013
Streptococcus pyogenes Streptococcus pyogenes MIC 250.0 nM 10.1021/acsmedchemlett.1c00683
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.06 ug.mL-1 10.1021/jm0580510
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.25 ug.mL-1 10.1128/aac.00344-06
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.015 ug.mL-1 10.1016/0960-894X(95)00072-2
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.015 ug.mL-1 10.1021/jm00021a013
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.06 ug.mL-1 10.1021/jm0580510
Streptococcus pyogenes Streptococcus pyogenes MIC90 2.0 ug.mL-1 10.1128/aac.00344-06
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC 0.016 ug.mL-1 10.1128/aac.01620-07
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC50 0.016 ug.mL-1 10.1128/aac.01620-07
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC90 0.016 ug.mL-1 10.1128/aac.01620-07
Stutzerimonas stutzeri Stutzerimonas stutzeri MIC 512.0 ug.mL-1 10.1128/aac.01456-09
Syncephalastrum racemosum Syncephalastrum racemosum IZ 19.0 mm 10.1016/j.ejmech.2009.09.002
Syncephalastrum racemosum Syncephalastrum racemosum Ratio 1.0 None 10.1016/j.ejmech.2009.09.002
Thomasclavelia ramosa Thomasclavelia ramosa MIC 0.125 ug.mL-1 10.1128/aac.01557-08
Veillonella parvula Veillonella parvula MIC 0.12 ug.mL-1 10.1128/aac.00355-08
Vibrio cholerae Vibrio cholerae IZ 7.0 mm 10.1007/s00044-012-0011-4
Vibrio cholerae Vibrio cholerae MIC 256.0 ug.mL-1 10.1007/s00044-012-0011-4
Vibrio cholerae Vibrio cholerae MIC 256.0 ug.mL-1 10.1016/j.ejmech.2011.02.066
Vibrio cholerae Vibrio cholerae MIC 256000.0 ug.mL-1 10.1007/s00044-012-0202-z
Vibrio parahaemolyticus Vibrio parahaemolyticus MIC 256.0 ug.mL-1 10.1016/j.ejmech.2011.02.066
Xanthomonas oryzae Xanthomonas oryzae IZ 8.0 mm 10.1016/j.ejmech.2010.12.005
Xanthomonas oryzae Xanthomonas oryzae IZ 9.0 mm 10.1016/j.ejmech.2011.12.012
Xanthomonas oryzae Xanthomonas oryzae MIC 18.0 ug.mL-1 10.1016/j.ejmech.2010.12.005
Xanthomonas oryzae Xanthomonas oryzae MIC 19.0 ug.mL-1 10.1016/j.ejmech.2011.12.012
Yersinia enterocolitica Yersinia enterocolitica MIC 0.38 ug.mL-1 10.1128/aac.01754-09
Yersinia enterocolitica Yersinia enterocolitica MIC 1.5 ug.mL-1 10.1128/aac.01754-09
Yersinia enterocolitica Yersinia enterocolitica MIC 24.0 ug.mL-1 10.1128/aac.01754-09
Yersinia sp. Yersinia sp. MIC90 64.0 ug.mL-1 10.1016/0960-894X(95)00072-2
Yersinia sp. Yersinia sp. MIC90 64.0 ug.mL-1 10.1021/jm00021a013
None ADMET AUC 48700.0 ng.hr.mL-1 10.1128/aac.01530-06
None ADMET AUC 73100.0 ng.hr.mL-1 10.1128/aac.01530-06
None ADMET CL 3.0 uL.min-1.(10^6cells)-1 10.6019/CHEMBL3301361
None ADMET CL 3.3 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET CL 14.11 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET CL 14.49 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET CL 15.57 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET CL 19.28 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET CL 21.53 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET CL 23.17 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET CL 24.15 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET CL 26.19 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET CL 26.79 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET CL 35.71 mL.min-1.kg-1 10.1128/aac.00405-07
None ADMET Cmax 24082.54 nM 10.1128/aac.00405-07
None ADMET Cmax 47070.41 nM 10.1128/aac.01530-06
None ADMET Cmax 47617.74 nM 10.1128/aac.01530-06
None ADMET Cmax 302673.71 nM 10.1128/aac.00405-07
None ADMET Drug uptake 0.03 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 0.3 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 0.6 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 0.8 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 1.7 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 2.0 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 2.1 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 2.9 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 5.0 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 5.5 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 5.9 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 7.8 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 8.2 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 9.3 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 9.9 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 10.1 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 10.4 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 10.5 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 11.6 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 11.8 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 12.5 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 13.3 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 13.6 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 14.1 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 15.5 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 17.2 ug ml-1 10.1128/aac.01530-06
None ADMET Drug uptake 17.4 ug ml-1 10.1128/aac.01530-06
None ADMET efflux_CL 0.003 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0035 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0043 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0056 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0085 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0086 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0092 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0093 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0098 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0123 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0128 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0184 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0186 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0217 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.0394 ml/min.Kg 10.1128/aac.00405-07
None ADMET efflux_CL 0.113 ml/min.Kg 10.1128/aac.00405-07
None ADMET fAUC 22500.0 ng.hr.mL-1 10.1128/aac.01530-06
None ADMET fAUC 60700.0 ng.hr.mL-1 10.1128/aac.01530-06
None ADMET fCmax 13.3 ug ml-1 10.1128/aac.01530-06
None ADMET fCmax 13.6 ug ml-1 10.1128/aac.01530-06
None ADMET ft1/2 1.4 hr 10.1128/aac.01530-06
None ADMET IC50 nan None 10.1128/aac.00457-09
None ADMET influx_CL 0.0016 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0018 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0019 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.002 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0022 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0024 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0025 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0026 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0032 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0033 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0041 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0047 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0053 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0055 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.0056 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.009 ml/min.Kg 10.1128/aac.00405-07
None ADMET influx_CL 0.013 ml/min.Kg 10.1128/aac.00405-07
None ADMET Km 4.5 ug ml-1 10.1128/aac.00405-07
None ADMET Km 9.3 ug ml-1 10.1128/aac.00405-07
None ADMET Km 17.8 ug ml-1 10.1128/aac.00405-07
None ADMET Km 34.0 ug ml-1 10.1128/aac.00405-07
None ADMET Km 35.9 ug ml-1 10.1128/aac.00405-07
None ADMET Km 48.6 ug ml-1 10.1128/aac.00405-07
None ADMET Km 54.9 ug ml-1 10.1128/aac.00405-07
None ADMET log10(%HIA +10) 2.016 None 10.1016/j.ejmech.2010.11.005
None ADMET MRT 1.3 hr 10.1124/dmd.108.020479
None ADMET Partition coefficient nan None 10.1016/j.bmcl.2004.02.068
None ADMET permeability 0.3 10'-4 cm/s 10.1021/jm901846t
None ADMET permeability nan None 10.1021/jm070836d
None ADMET permeability nan None 10.1021/jm701044r
None ADMET PPB 18.0 % 10.1128/aac.01530-06
None ADMET PPB 30.0 % 10.1016/j.ejmech.2020.112829
None ADMET Ratio 0.0 None 10.1016/j.bmcl.2004.02.068
None ADMET Ratio 0.01 None 10.1128/aac.01530-06
None ADMET Ratio 0.13 None 10.1128/aac.00405-07
None ADMET Ratio 0.16 None 10.1128/aac.00405-07
None ADMET Ratio 0.18 None 10.1128/aac.00405-07
None ADMET Ratio 0.19 None 10.1128/aac.00405-07
None ADMET Ratio 0.23 None 10.1128/aac.00405-07
None ADMET Ratio 0.24 None 10.1128/aac.00405-07
None ADMET Ratio 0.26 None 10.1128/aac.00405-07
None ADMET Ratio 0.34 None 10.1128/aac.00405-07
None ADMET Ratio 0.41 None 10.1128/aac.00405-07
None ADMET Ratio 0.42 None 10.1128/aac.00405-07
None ADMET Ratio 0.46 None 10.1128/aac.00405-07
None ADMET Ratio 0.48 None 10.1128/aac.00405-07
None ADMET Ratio 0.53 None 10.1128/aac.00405-07
None ADMET Ratio 0.63 None 10.1128/aac.00405-07
None ADMET Ratio 0.64 None 10.1128/aac.00405-07
None ADMET Ratio 0.8 None 10.1128/aac.01530-06
None ADMET Ratio 0.9 None 10.1128/aac.01530-06
None ADMET Ratio 1.0 None 10.1016/j.bmcl.2004.02.068
None ADMET Ratio 1.4 None 10.1128/aac.00405-07
None ADMET Ratio nan None 10.1016/j.bmcl.2004.02.068
None ADMET T1/2 0.2 hr 10.1016/S0960-894X(01)80141-4
None ADMET T1/2 0.3 hr 10.1128/aac.00405-07
None ADMET T1/2 1.1 hr 10.1124/dmd.108.020479
None ADMET T1/2 1.3 hr 10.1128/aac.01530-06
None ADMET Tmax 1.5 hr 10.1128/aac.01530-06
None ADMET Vdss 0.25 L.kg-1 10.1124/dmd.108.020479
None ADMET Vmax 0.08 ug/min.kg 10.1128/aac.00405-07
None ADMET Vmax 0.36 ug/min.kg 10.1128/aac.00405-07
None ADMET Vmax 0.42 ug/min.kg 10.1128/aac.00405-07
None ADMET Vmax 0.62 ug/min.kg 10.1128/aac.00405-07
None ADMET Vmax 0.78 ug/min.kg 10.1128/aac.00405-07
None ADMET Vmax 0.89 ug/min.kg 10.1128/aac.00405-07
None ADMET Vmax 23.0 ug/min.kg 10.1128/aac.00405-07
None Erythrocyte LC50 nan None 10.1021/acs.jnatprod.5b01129
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx1000865
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity Hepatotoxicity nan None 10.1124/dmd.110.035113
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 2.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity LTKB_BD DILI severity score 3.0 None 10.1016/j.drudis.2011.05.007
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value 0.1 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Liposome Other 9.0 None 10.1021/jm991156g
None Liposome Other 17.0 None 10.1021/jm991156g
None NON-PROTEIN TARGET Activity 19.6 % 10.1128/aac.00081-08
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00729-05
None NON-PROTEIN TARGET Anticonvulsant activity nan None 10.1016/s0960-894x(03)00535-3
None NON-PROTEIN TARGET Fu 0.85 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 0.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 1.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 7.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 8.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IZ 14.0 mm 10.1016/j.ejmech.2011.12.021
None NON-PROTEIN TARGET MBC 4.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC 8.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC 16.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC90 16.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.047 ug.mL-1 10.1128/aac.00684-07
None NON-PROTEIN TARGET MIC 0.125 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.125 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00081-08
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00791-09
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.4 ug.mL-1 10.1021/jm00178a011
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00427-09
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.01463-07
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC 1.5 ug.mL-1 10.1128/aac.00684-07
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00242-07
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.01252-09
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.01463-07
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.00427-09
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.01252-09
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.01463-07
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.01463-07
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.01581-08
None NON-PROTEIN TARGET MIC 12.0 ug.mL-1 10.1128/aac.01585-09
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.01152-06
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.01463-07
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.01634-07
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.00046-09
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.00128-10
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.01284-08
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.01463-07
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.00128-10
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.00242-07
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.00791-09
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.01284-08
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.01585-09
None NON-PROTEIN TARGET MIC 512.0 ug.mL-1 10.1128/aac.01600-06
None NON-PROTEIN TARGET MIC 1024.0 ug.mL-1 10.1128/aac.00128-10
None NON-PROTEIN TARGET MIC 4000.0 nM 10.1021/jm031089x
None NON-PROTEIN TARGET MIC50 0.016 ug.mL-1 10.1128/aac.00056-07
None NON-PROTEIN TARGET MIC50 0.125 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC50 0.25 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC50 0.5 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC50 1.0 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
None NON-PROTEIN TARGET MIC90 0.094 ug.mL-1 10.1128/aac.00056-07
None NON-PROTEIN TARGET MIC90 0.25 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC90 0.5 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC90 1.0 ug.mL-1 10.1128/aac.01557-08
None NON-PROTEIN TARGET MIC90 2.0 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
None No relevant target CLogP 0.33 None 10.1021/jm9810102
None No relevant target Daq 6.8 10'-6cm2/s 10.1021/jm901846t
None No relevant target GOF 3.1 None 10.1021/jm9810102
None No relevant target LogD -1.98 None 10.1021/jm9810102
None No relevant target LogD -1.7 None 10.1021/jm9810102
None No relevant target LogD -1.6 None 10.1021/jm9810102
None No relevant target LogD -1.56 None 10.1021/jm9810102
None No relevant target LogD -1.22 None 10.1021/jm9810102
None No relevant target LogP -1.71 None 10.1021/jm901846t
None No relevant target LogP -1.71 None 10.1021/jm9810102
None No relevant target pKa 2.4 None 10.1016/j.ejmech.2009.06.004
None No relevant target pKa 2.6 None 10.1007/s11095-013-1232-z
None No relevant target pKa 2.6 None 10.1021/jm901846t
None No relevant target pKa 9.61 None 10.1021/jm9810102
None No relevant target pKa_A1 4.03 None 10.6019/CHEMBL3301361
None No relevant target pKa_A2 9.77 None 10.6019/CHEMBL3301361
None No relevant target pKa_B1 7.52 None 10.6019/CHEMBL3301361
None No relevant target Solubility 3900.0 ug.mL-1 10.1016/j.bmc.2010.08.003
None No relevant target Solubility nan ug.mL-1 10.1016/j.bmcl.2004.02.068
None Osteoblast Activity nan None 10.1128/aac.00729-05
None Phospholipidosis Phospholipidosis nan None 10.1080/15376510701857262
None Unchecked Ac50 1.585 uM None
None Unchecked Ac50 10.0 uM None
None Unchecked AC50 1584.9 nM None
None Unchecked AC50 10000.0 nM None
None Unchecked Activity 100.0 None 10.1128/aac.01439-06
None Unchecked Activity 120.0 % 10.1128/aac.01164-08
None Unchecked Activity 175.0 % 10.1128/aac.01164-08
None Unchecked FC 10.0 None 10.1128/aac.00537-07
None Unchecked FC 16.0 None 10.1021/acs.jmedchem.0c02059
None Unchecked FC 16.0 None 10.1021/acs.jmedchem.1c00858
None Unchecked Hepatotoxicity (acute) 10.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 7.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 2.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 0.006 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.019 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.022 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.029 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.034 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.035 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.047 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.049 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.05 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.051 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.059 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.066 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.068 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.077 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.079 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.08 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.116 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.117 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.165 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 1.103 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 9000000.0 nM 10.1016/j.bmc.2016.08.023
None Unchecked IC50 nan None 10.1128/aac.01566-08
None Unchecked IC50 nan None None
None Unchecked Kcat 2.0 /s 10.1128/aac.01410-08
None Unchecked Kcat 2.5 /s 10.1128/aac.01410-08
None Unchecked Kcat 23.0 /s 10.1128/aac.01462-06
None Unchecked Kcat 30.0 /s 10.1128/aac.01164-08
None Unchecked Kcat 60.0 /s 10.1128/aac.00614-07
None Unchecked Kcat 88.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 91.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 112.0 /s 10.1128/aac.00017-09
None Unchecked Kcat 149.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 258.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 624.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 900.0 /s 10.1128/aac.00614-07
None Unchecked Kcat 1042.0 /s 10.1128/aac.01442-09
None Unchecked Kcat 1125.0 /s 10.1128/aac.01058-06
None Unchecked Kcat/Km 0.21 None 10.1128/aac.01462-06
None Unchecked Kcat/Km 2.0 /uM/s 10.1128/aac.01164-08
None Unchecked Kcat/Km 3.3 /s/microM 10.1128/aac.00017-09
None Unchecked Kcat/Km 3.5 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 3.7 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 5.4 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 5.5 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 7.3 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 8.0 None 10.1128/aac.00614-07
None Unchecked Kcat/Km 8.5 None 10.1128/aac.00614-07
None Unchecked Kcat/Km 10.4 /uM/s 10.1128/aac.01442-09
None Unchecked Kcat/Km 70.0 /uM/s 10.1128/aac.01410-08
None Unchecked Kcat/Km 75.0 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 100.0 /uM/s 10.1128/aac.01410-08
None Unchecked Kcat/Km 3300.0 /mM/s 10.1128/aac.01082-06
None Unchecked Ki nan None None
None Unchecked Km 7.5 /s/microM 10.1128/aac.00614-07
None Unchecked Km 22.0 ug ml-1 10.1016/s0960-894x(99)00549-1
None Unchecked Km 245.0 /s/microM 10.1128/aac.00614-07
None Unchecked Km 10000.0 nM 10.1128/aac.01164-08
None Unchecked Km 12000.0 nM 10.1128/aac.01058-06
None Unchecked Km 15000.0 nM 10.1128/aac.01058-06
None Unchecked Km 25000.0 nM 10.1128/aac.01410-08
None Unchecked Km 26000.0 nM 10.1128/aac.01058-06
None Unchecked Km 30000.0 nM 10.1128/aac.01410-08
None Unchecked Km 40000.0 nM 10.1128/aac.01058-06
None Unchecked Km 48000.0 nM 10.1128/aac.01058-06
None Unchecked Km 101000.0 nM 10.1128/aac.01442-09
None Unchecked Km 110000.0 nM 10.1128/aac.01462-06
None Unchecked Km 114000.0 nM 10.1128/aac.01058-06
None Unchecked Km 180000.0 nM 10.1128/aac.01082-06
None Unchecked Potency 1412.5 nM None
None Unchecked Potency 2238.7 nM None
None Unchecked Potency 12589.3 nM None
None Unchecked Potency 29092.9 nM None
None Unchecked Ratio 4.0 None 10.1128/aac.00614-07
None Unchecked Ratio 8.0 None 10.1128/aac.00614-07
None Unchecked Vmax 2.94 None 10.1016/s0960-894x(99)00549-1
None Unchecked Vmax / Km 11.1 None 10.1016/s0960-894x(99)00549-1

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT006857 CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O.NC(=O)[C@H](N)c1ccc(O)cc1>>CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O enzymemap_76181
AKRT006891 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O>>CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O MNXR133717
AKRT006892 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O>>CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O.NC(=O)[C@H](N)c1ccc(O)cc1 None
AKRT006893 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O>>NC(=O)[C@H](N)c1ccc(O)cc1 enzymemap_76181
AKRT006894 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O>>N[C@@H](C(=O)O)c1ccc(O)cc1 MNXR133717
AKRT010985 COC(=O)C(N)c1ccc(O)cc1.CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O>>CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O enzymemap_76172