Glu-Glu
AlkaPlorer ID: AK022657
Synonym: 'H-Glu-Glu-OH', 'H-L-Glu-L-Glu-OH', 'L-Glu-L-Glu'
IUPAC Name: (2S)-2-[[(2S)-2-amino-4-carboxybutanoyl]amino]pentanedioic acid
Structure
SMILES: N[C@@H](CCC(=O)O)C(O)=N[C@@H](CCC(=O)O)C(=O)O
InChI: InChI=1S/C10H16N2O7/c11-5(1-3-7(13)14)9(17)12-6(10(18)19)2-4-8(15)16/h5-6H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
InChIKey: KOSRFJWDECSPRO-WDSKDSINSA-N
Reference
PubChem CID: 439500
CAS: 3929-61-1
LOTUS: LTS0054360
SuperNatural Ⅲ: SN0191320-01
NPASS: NPC143722
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 276.245
TPSA？: 170.51
MolLogP？: -0.546999999999999
Number of H-Donors: 5
Number of H-Acceptors: 5
RingCount: 0
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Oligopeptide transporter small intestine isoform | EC50 | 1000000.0 | nM | 10.1021/jm0511029 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | IC50 | 620000.0 | nM | 10.1021/jm0511029 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | max activation | 111.0 | % | 10.1021/jm0511029 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | Ratio | 110.0 | None | 10.1021/jm0511029 |
| Rattus norvegicus | Glutamate carboxypeptidase II | IC50 | 750.0 | nM | 10.1021/jm000406m |
| Saccharomyces cerevisiae | General amino-acid permease GAP1 | Inhibition | 15.0 | % | 10.1038/nchembio.132 |