Oridamycin A
AlkaPlorer ID: AK023074
Synonym: None
IUPAC Name: (16R,17R,18S,21S)-18-hydroxy-17,21-dimethyl-10-azapentacyclo[11.8.0.03,11.04,9.016,21]henicosa-1,3(11),4,6,8,12-hexaene-17-carboxylic acid
Structure
SMILES: C[C@]1(C(=O)O)[C@@H](O)CC[C@]2(C)C3=CC4=C(C=C3CC[C@@H]12)NC1=CC=CC=C14
InChI: InChI=1S/C23H25NO3/c1-22-10-9-20(25)23(2,21(26)27)19(22)8-7-13-11-18-15(12-16(13)22)14-5-3-4-6-17(14)24-18/h3-6,11-12,19-20,24-25H,7-10H2,1-2H3,(H,26,27)/t19-,20+,22-,23-/m1/s1
InChIKey: XUTJPVCJXVRRLB-IRMYBRCSSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | None | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 363.4570000000001
TPSA？: 73.32
MolLogP？: 4.386800000000004
Number of H-Donors: 3
Number of H-Acceptors: 2
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Phoma | Phoma | MIC | 242.0 | ug.mL-1 | 10.1021/np1000522 |
| Saccharomyces cerevisiae | Saccharomyces cerevisiae | MIC | nan | None | 10.1021/np1000522 |
| Saprolegnia parasitica | Saprolegnia parasitica | MIC | 3.0 | ug.mL-1 | 10.1021/np1000522 |