10'-Hydroxyusambarensine
AlkaPlorer ID: AK023084
Synonym: ''
IUPAC Name: 1-[[(2R,3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]methyl]-9H-pyrido[3,4-b]indol-6-ol
Structure
SMILES: C/C=C1/CN2CCC3=C(NC4=CC=CC=C34)[C@@H]2C[C@@H]1CC1=NC=CC2=C1NC1=CC=C(O)C=C12
InChI: InChI=1S/C29H28N4O/c1-2-17-16-33-12-10-22-20-5-3-4-6-24(20)32-29(22)27(33)14-18(17)13-26-28-21(9-11-30-26)23-15-19(34)7-8-25(23)31-28/h2-9,11,15,18,27,31-32,34H,10,12-14,16H2,1H3/b17-2-/t18-,27-/m0/s1
InChIKey: UXVNNVWPICKMTE-JKCZZUPASA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Strychnos usambarensis | Strychnos | Loganiaceae | Gentianales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 448.5700000000002
TPSA？: 67.94
MolLogP？: 6.011100000000005
Number of H-Donors: 3
Number of H-Acceptors: 3
RingCount: 7
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 0.113 | ug.mL-1 | 10.1021/np980375m |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 0.122 | ug.mL-1 | 10.1021/np980375m |