Glycozolidine
AlkaPlorer ID: AK023279
Synonym: None
IUPAC Name: 2,6-dimethoxy-3-methyl-9H-carbazole
Structure
SMILES: COC1=CC=C2NC3=CC(OC)=C(C)C=C3C2=C1
InChI: InChI=1S/C15H15NO2/c1-9-6-11-12-7-10(17-2)4-5-13(12)16-14(11)8-15(9)18-3/h4-8,16H,1-3H3
InChIKey: MKQKWPIESXSKSS-UHFFFAOYSA-N
Reference
Glycophymoline, a new minor quinazoline alkaloid from Glycosmis pentaphylla
PubChem CID: 147297
CAS: 29093-41-2
LOTUS: LTS0097554
COCONUT: CNP0232841
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Glycosmis mauritiana | Glycosmis | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 241.29
TPSA？: 34.25
MolLogP？: 3.646720000000002
Number of H-Donors: 1
Number of H-Acceptors: 2
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Chlorocebus sabaeus | Vero | IC50 | nan | None | 10.1016/j.bmc.2016.12.038 |
| Homo sapiens | Raji | Activity | 60.0 | % | 10.1021/np0400611 |
| Homo sapiens | Raji | Activity | 80.0 | % | 10.1021/np0400611 |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC90 | 50000.0 | nM | 10.1016/j.bmc.2016.12.038 |
| None | Unchecked | Activity | 24.3 | % | 10.1021/np0400611 |
| None | Unchecked | Activity | 51.3 | % | 10.1021/np0400611 |
| None | Unchecked | Activity | 76.0 | % | 10.1021/np0400611 |
| None | Unchecked | Activity | 100.0 | % | 10.1021/np0400611 |