Porphobilinogen
AlkaPlorer ID: AK023495
Synonym: 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propanoic acid
IUPAC Name: 3-[5-(azaniumylmethyl)-4-(carboxylatomethyl)-1H-pyrrol-3-yl]propanoate
Structure
SMILES: [NH3+]CC1=C(CC(=O)[O-])C(CCC(=O)[O-])=CN1
InChI: InChI=1S/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16)/p-1
InChIKey: QSHWIQZFGQKFMA-UHFFFAOYSA-M
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Homo sapiens | Homo | Hominidae | Primates | Mammalia | Chordata | Metazoa | Eukaryota |
| Saccharomyces cerevisiae | Saccharomyces | Saccharomycetaceae | Saccharomycetales | Saccharomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 225.224
TPSA？: 123.69
MolLogP？: -3.268499999999998
Number of H-Donors: 2
Number of H-Acceptors: 4
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Macrophage migration inhibitory factor | IC50 | 400000.0 | nM | 10.1016/j.bmcl.2021.128445 |
| Homo sapiens | Uracil nucleotide/cysteinyl leukotriene receptor | Inhibition | nan | % | None |