10-hydroxycanthin-6-one
AlkaPlorer ID: AK023624
Synonym: 'ervine', '10-Hydroxycanthin-6-one'
IUPAC Name: 12-hydroxy-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one
Structure
SMILES: O=C1C=CC2=C3C(=CC=N2)C2=CC(O)=CC=C2N13
InChI: InChI=1S/C14H8N2O2/c17-8-1-3-12-10(7-8)9-5-6-15-11-2-4-13(18)16(12)14(9)11/h1-7,17H
InChIKey: FZLISVGXWLVEPB-UHFFFAOYSA-N
Reference
A study of the herb Aerva lanata. III. Alkaloids
PubChem CID: 158929
CAS: 86293-41-6
LOTUS: LTS0074837
SuperNatural Ⅲ: SN0099667
COCONUT: CNP0289996
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Hannoa chlorantha | Hannoa | Simaroubaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 236.23
TPSA？: 54.6
MolLogP？: 2.1442999999999994
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus cereus | Bacillus cereus | MIC | 16.0 | ug.mL-1 | 10.1016/j.bmcl.2018.06.001 |
| Bacillus subtilis | Bacillus subtilis | MIC | 64.0 | ug.mL-1 | 10.1016/j.bmcl.2018.06.001 |
| Homo sapiens | KB | ED50 | 2.2 | ug ml-1 | 10.1021/np50026a016 |
| Ralstonia solanacearum | Ralstonia solanacearum | MIC | 64.0 | ug.mL-1 | 10.1016/j.bmcl.2018.06.001 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 64.0 | ug.mL-1 | 10.1016/j.bmcl.2018.06.001 |