Molecule

benzo[g]isoquinoline-5,10-dione

AlkaPlorer ID: AK023747

Synonym: None

IUPAC Name: benzo[g]isoquinoline-5,10-dione

Structure

SMILES: O=C1C2=CC=CC=C2C(=O)C2=CN=CC=C12

InChI: InChI=1S/C13H7NO2/c15-12-8-3-1-2-4-9(8)13(16)11-7-14-6-5-10(11)12/h1-7H

InChIKey: ZLLVUAAESHIVAZ-UHFFFAOYSA-N

Reference

Azaanthraquinone: An Antimicrobial Alkaloid from<i>Mitracarpus scaber</i>

PubChem CID: 100650

CAS: 46492-08-4

LOTUS: LTS0205231

SuperNatural Ⅲ: SN0473603

COCONUT: CNP0345189

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain

Properties Information

Molecule Weight: 209.204

TPSA？: 47.03

MolLogP？: 1.857

Number of H-Donors: 0

Number of H-Acceptors: 3

RingCount: 3

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Aspergillus niger	Aspergillus niger	MIC	12.5	ug.mL-1	10.1016/j.bmcl.2004.12.059
Bacillus subtilis	Bacillus subtilis	MIC	3.13	ug.mL-1	10.1016/j.bmcl.2004.12.059
Cyberlindnera jadinii	Cyberlindnera jadinii	MIC	12.5	ug.mL-1	10.1016/j.bmcl.2004.12.059
Escherichia coli	Escherichia coli	MIC	100.0	ug.mL-1	10.1016/j.bmcl.2004.12.059
Helicobacter pylori	Helicobacter pylori	Activity	4.65	log10CFU/ml	10.1021/acs.jnatprod.1c01163
Helicobacter pylori	Helicobacter pylori	Activity	51.0	%	10.1021/acs.jnatprod.1c01163
Helicobacter pylori	Helicobacter pylori	Activity	100.0	%	10.1021/acs.jnatprod.1c01163
Helicobacter pylori	Helicobacter pylori	MIC	0.0625	ug.mL-1	10.1021/acs.jnatprod.1c01163
Helicobacter pylori	Helicobacter pylori	MIC	0.125	ug.mL-1	10.1021/acs.jnatprod.1c01163
Helicobacter pylori	Helicobacter pylori	Ratio	512.0	None	10.1021/acs.jnatprod.1c01163
Homo sapiens	Monoamine oxidase A	IC50	20200.0	nM	10.1016/j.bmc.2021.116558
Homo sapiens	Monoamine oxidase B	IC50	4280.0	nM	10.1016/j.bmc.2021.116558
Homo sapiens	Raji	Activity	10.0	%	10.1021/np50065a012
Homo sapiens	Raji	Activity	80.0	%	10.1021/np50065a012
Mucor mucedo	Mucor mucedo	MIC	6.25	ug.mL-1	10.1016/j.bmcl.2004.12.059
Proteus vulgaris	Proteus vulgaris	MIC	50.0	ug.mL-1	10.1016/j.bmcl.2004.12.059
Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	6.25	ug.mL-1	10.1016/j.bmcl.2004.12.059
Rhizopus microsporus var. chinensis	Rhizopus microsporus var. chinensis	MIC	12.5	ug.mL-1	10.1016/j.bmcl.2004.12.059
Rhodotorula mucilaginosa	Rhodotorula mucilaginosa	MIC	6.25	ug.mL-1	10.1016/j.bmcl.2004.12.059
Saccharomyces cerevisiae	Saccharomyces cerevisiae	MIC	12.5	ug.mL-1	10.1016/j.bmcl.2004.12.059
Schizosaccharomyces pombe	Schizosaccharomyces pombe	MIC	3.13	ug.mL-1	10.1016/j.bmcl.2004.12.059
Staphylococcus aureus	Staphylococcus aureus	MIC	6.25	ug.mL-1	10.1016/j.bmcl.2004.12.059
None	NON-PROTEIN TARGET	MIC	3.13	ug.mL-1	10.1016/j.bmcl.2004.12.059
None	Unchecked	Inhibition	0.0	%	10.1021/np50065a012
None	Unchecked	Inhibition	13.0	%	10.1021/np50065a012
None	Unchecked	Inhibition	69.5	%	10.1021/np50065a012
None	Unchecked	Inhibition	100.0	%	10.1021/np50065a012
None	Unchecked	Ratio IC50	0.21	None	10.1016/j.bmc.2021.116558