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7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

AlkaPlorer ID: AK023788

Synonym: None

IUPAC Name: (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Structure

SMILES: CO/N=C(\C(O)=N[C@@H]1C(=O)N2C(C(=O)O)=C(CSC3=NC(=O)C(=O)NN3C)CS[C@H]12)C1=CSC(=N)N1

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InChI: InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1

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InChIKey: VAAUVRVFOQPIGI-SPQHTLEESA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Stachybotrys chartarum Stachybotrys Stachybotryaceae Hypocreales Sordariomycetes Ascomycota Fungi Eukaryota

Properties Information

Molecule Weight: 554.5920000000001

TPSA？: 219.18

MolLogP？: -0.9406299999999992

Number of H-Donors: 5

Number of H-Acceptors: 13

RingCount: 4

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter Acinetobacter Activity 0.0 % 10.1128/aac.00149-08
Acinetobacter Acinetobacter Activity 44.7 % 10.1128/aac.00149-08
Acinetobacter Acinetobacter MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Acinetobacter Acinetobacter MIC 16.0 ug.mL-1 10.1128/aac.00149-08
Acinetobacter Acinetobacter MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Acinetobacter Acinetobacter MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.00963-09
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1016/j.bmcl.2012.09.095
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1021/acs.jnatprod.9b00305
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1021/acs.jnatprod.9b01000
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00336-08
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01197-09
Acinetobacter baumannii Acinetobacter baumannii MIC 128.0 ug.mL-1 10.1128/aac.01139-06
Acinetobacter baumannii Acinetobacter baumannii MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Acinetobacter baumannii Acinetobacter baumannii MIC50 8.0 ug.mL-1 10.1128/aac.01315-06
Acinetobacter baumannii Acinetobacter baumannii MIC50 32.0 ug.mL-1 10.1128/aac.00336-08
Acinetobacter baumannii Acinetobacter baumannii MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter baumannii Acinetobacter baumannii MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Acinetobacter baumannii Acinetobacter baumannii MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter baumannii Acinetobacter baumannii MIC90 64.0 ug.mL-1 10.1128/aac.01315-06
Acinetobacter baumannii Acinetobacter baumannii MIC90 128.0 ug.mL-1 10.1128/aac.00336-08
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC 4.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter haemolyticus Acinetobacter haemolyticus MBC 4.0 ug ml-1 10.1016/j.bmcl.2013.12.002
Acinetobacter haemolyticus Acinetobacter haemolyticus MIC 0.5 ug.mL-1 10.1128/aac.01047-08
Acinetobacter haemolyticus Acinetobacter haemolyticus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2013.12.002
Acinetobacter haemolyticus Acinetobacter haemolyticus MIC50 2.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter haemolyticus Acinetobacter haemolyticus MIC90 8.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.5 ug.mL-1 10.1128/aac.01047-08
Acinetobacter lwoffii Acinetobacter lwoffii MIC50 2.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter lwoffii Acinetobacter lwoffii MIC90 8.0 ug.mL-1 10.1128/aac.01047-08
Acinetobacter pittii Acinetobacter pittii Activity 63.2 % 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC 8.0 ug.mL-1 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC 32.0 ug.mL-1 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC50 64.0 ug.mL-1 10.1128/aac.01624-09
Acinetobacter pittii Acinetobacter pittii MIC90 64.0 ug.mL-1 10.1128/aac.01624-09
Acinetobacter radioresistens Acinetobacter radioresistens MIC 2.0 ug.mL-1 10.1128/aac.00999-08
Acinetobacter radioresistens Acinetobacter radioresistens MIC 4.0 ug.mL-1 10.1128/aac.00999-08
Acinetobacter sp. Acinetobacter sp. Activity 15.0 % 10.1128/aac.01808-09
Actinomyces israelii Actinomyces israelii MIC50 0.125 ug.mL-1 10.1128/aac.01788-09
Actinomyces israelii Actinomyces israelii MIC90 0.5 ug.mL-1 10.1128/aac.01788-09
Anaerococcus prevotii Anaerococcus prevotii MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Anaerococcus prevotii Anaerococcus prevotii MIC50 0.25 ug.mL-1 10.1128/aac.01788-09
Anaerococcus prevotii Anaerococcus prevotii MIC90 0.5 ug.mL-1 10.1128/aac.01788-09
Anaerococcus tetradius Anaerococcus tetradius MIC 0.25 ug.mL-1 10.1128/aac.00910-07
Anaerococcus tetradius Anaerococcus tetradius MIC50 0.25 ug.mL-1 10.1128/aac.00910-07
Anaerococcus tetradius Anaerococcus tetradius MIC50 0.25 ug.mL-1 10.1128/aac.01788-09
Anaerococcus tetradius Anaerococcus tetradius MIC90 0.5 ug.mL-1 10.1128/aac.01788-09
Anaerococcus vaginalis Anaerococcus vaginalis MIC50 0.25 ug.mL-1 10.1128/aac.01788-09
Anaerococcus vaginalis Anaerococcus vaginalis MIC90 16.0 ug.mL-1 10.1128/aac.01788-09
Bacillus cereus Bacillus cereus MBC 64.0 ug ml-1 10.1016/j.bmcl.2013.12.002
Bacillus cereus Bacillus cereus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2013.12.002
Bacillus cereus Bacillus cereus MIC 125.0 ug.mL-1 10.1007/s00044-009-9279-4
Bacillus clausii Beta-lactamase Activity 0.4 None 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat 30.0 /s 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat/Km 0.03 /uM/s 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Km 950000.0 nM 10.1128/aac.00537-07
Bacillus licheniformis Beta-lactamase Activity 1894.0 M min-1 (M of enzyme)-1 10.1021/jm950886v
Bacillus subtilis Bacillus subtilis IZ 16.0 mm 10.1007/s00044-009-9178-8
Bacillus subtilis Bacillus subtilis MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Bacillus subtilis Bacillus subtilis MIC 0.25 ug.mL-1 10.1016/s0960-894x(01)00802-2
Bacillus subtilis Bacillus subtilis MIC 1.0 ug.mL-1 10.1128/aac.01790-09
Bacillus subtilis Bacillus subtilis MIC 1.613 ug.mL-1 10.1007/s00044-011-9607-3
Bacillus subtilis Bacillus subtilis MIC 1.613 ug.mL-1 10.1007/s00044-011-9796-9
Bacillus subtilis Bacillus subtilis MIC 1.613 ug.mL-1 10.1016/j.ejmech.2010.02.040
Bacillus subtilis Bacillus subtilis MIC 1.613 ug.mL-1 10.1016/j.ejmech.2010.07.048
Bacillus subtilis Bacillus subtilis MIC 1.613 ug.mL-1 10.1016/j.ejmech.2010.09.015
Bacillus subtilis Bacillus subtilis MIC 1.613 ug.mL-1 10.1016/j.ejmech.2012.12.057
Bacillus subtilis Bacillus subtilis MIC 3.9 ug.mL-1 10.1007/s00044-009-9279-4
Bacillus subtilis Bacillus subtilis MIC 5.0 ug.mL-1 10.1007/s00044-009-9178-8
Bacillus thuringiensis Bacillus thuringiensis MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Bacteroides caccae Bacteroides caccae MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides caccae Bacteroides caccae MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides fragilis Bacteroides fragilis MIC 0.25 ug.mL-1 10.1128/aac.00910-07
Bacteroides fragilis Bacteroides fragilis MIC 64.0 ug.mL-1 10.1016/j.bmc.2020.115776
Bacteroides fragilis Bacteroides fragilis MIC50 32.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides fragilis Bacteroides fragilis MIC50 64.0 ug.mL-1 10.1128/aac.00910-07
Bacteroides fragilis Bacteroides fragilis MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides fragilis Bacteroides fragilis MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides fragilis Bacteroides fragilis MIC90 128.0 ug.mL-1 10.1128/aac.00910-07
Bacteroides ovatus Bacteroides ovatus MIC 64.0 ug.mL-1 10.1128/aac.00910-07
Bacteroides ovatus Bacteroides ovatus MIC50 64.0 ug.mL-1 10.1128/aac.00910-07
Bacteroides ovatus Bacteroides ovatus MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides ovatus Bacteroides ovatus MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides ovatus Bacteroides ovatus MIC90 128.0 ug.mL-1 10.1128/aac.00910-07
Bacteroides sp. Bacteroides sp. Activity nan None 10.1128/aac.00355-06
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity nan None 10.1128/aac.00910-07
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 64.0 ug.mL-1 10.1128/aac.00910-07
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 128.0 ug.mL-1 10.1128/aac.00910-07
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 128.0 ug.mL-1 10.1128/aac.00910-07
Bacteroides uniformis Bacteroides uniformis MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Bacteroides uniformis Bacteroides uniformis MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Bos taurus Serum albumin PPB 20.2 % 10.1128/aac.00427-08
Bos taurus Serum albumin PPB 30.7 % 10.1128/aac.00427-08
Burkholderia cepacia Burkholderia cepacia MIC 0.03 ug.mL-1 10.1128/aac.01021-08
Burkholderia cepacia Burkholderia cepacia MIC 2.0 ug.mL-1 10.1128/aac.01047-08
Burkholderia cepacia Burkholderia cepacia MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Burkholderia cepacia Burkholderia cepacia MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Burkholderia cepacia Burkholderia cepacia MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Burkholderia cepacia Burkholderia cepacia MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Candida albicans Candida albicans MIC 125.0 ug.mL-1 10.1007/s00044-009-9279-4
Canis lupus familiaris Canis familiaris CL 2.5 mL.min-1.kg-1 10.1124/dmd.112.049312
Canis lupus familiaris Canis familiaris CL 2.907 mL.min-1.kg-1 10.1124/dmd.112.049312
Canis lupus familiaris Serum PPB 20.9 % 10.1128/aac.00271-10
Chlamydia pneumoniae Chlamydia pneumoniae MIC nan None 10.1128/aac.00046-09
Chlamydia trachomatis Chlamydia trachomatis MIC 32.0 ug.mL-1 10.1128/aac.00046-09
Chryseobacterium indologenes Chryseobacterium indologenes MIC nan None 10.1128/aac.01607-08
Citrobacter Citrobacter Activity 1.1 % 10.1128/aac.00381-08
Citrobacter Citrobacter Activity 1.8 % 10.1128/aac.00381-08
Citrobacter Citrobacter Activity 3.6 % 10.1128/aac.00381-08
Citrobacter Citrobacter Activity 54.5 % 10.1128/aac.00381-08
Citrobacter Citrobacter Activity 97.8 % 10.1128/aac.00381-08
Citrobacter Citrobacter MIC 0.015 ug.mL-1 10.1128/aac.00381-08
Citrobacter Citrobacter MIC 8.0 ug.mL-1 10.1128/aac.00381-08
Citrobacter Citrobacter MIC50 0.12 ug.mL-1 10.1128/aac.00381-08
Citrobacter Citrobacter MIC50 64.0 ug.mL-1 10.1128/aac.00381-08
Citrobacter Citrobacter MIC90 0.5 ug.mL-1 10.1128/aac.00381-08
Citrobacter Citrobacter MIC90 64.0 ug.mL-1 10.1128/aac.00381-08
Citrobacter freundii Citrobacter freundii Activity 0.0 % 10.1128/aac.00149-08
Citrobacter freundii Citrobacter freundii Activity 6.1 % 10.1128/aac.00149-08
Citrobacter freundii Citrobacter freundii Activity 45.0 % 10.1128/aac.00426-09
Citrobacter freundii Citrobacter freundii Activity 67.0 % 10.1128/aac.01808-09
Citrobacter freundii Citrobacter freundii Activity 100.0 % 10.1128/aac.00149-08
Citrobacter freundii Citrobacter freundii MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Citrobacter freundii Citrobacter freundii MIC 0.03 ug.mL-1 10.1128/aac.01197-09
Citrobacter freundii Citrobacter freundii MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Citrobacter freundii Citrobacter freundii MIC 0.12 ug.mL-1 10.1128/aac.01047-08
Citrobacter freundii Citrobacter freundii MIC 0.25 ug.mL-1 10.1021/jm950886v
Citrobacter freundii Citrobacter freundii MIC 2.0 ug.mL-1 10.1128/aac.01790-09
Citrobacter freundii Citrobacter freundii MIC 4.0 ug.mL-1 10.1128/aac.00149-08
Citrobacter freundii Citrobacter freundii MIC 4.0 ug.mL-1 10.1128/aac.01047-08
Citrobacter freundii Citrobacter freundii MIC 256.0 ug.mL-1 10.1128/aac.01405-06
Citrobacter freundii Citrobacter freundii MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Citrobacter freundii Citrobacter freundii MIC50 0.12 ug.mL-1 10.1128/aac.00149-08
Citrobacter freundii Citrobacter freundii MIC50 0.25 ug.mL-1 10.1128/aac.01197-09
Citrobacter freundii Citrobacter freundii MIC50 0.5 ug.mL-1 10.1128/aac.01047-08
Citrobacter freundii Citrobacter freundii MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Citrobacter freundii Citrobacter freundii MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Citrobacter freundii Citrobacter freundii MIC90 0.5 ug.mL-1 10.1128/aac.00149-08
Citrobacter freundii Citrobacter freundii MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Citrobacter freundii Citrobacter freundii MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Citrobacter freundii Citrobacter freundii MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Citrobacter freundii Citrobacter freundii MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Citrobacter koseri Citrobacter koseri MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Citrobacter koseri Citrobacter koseri MIC50 0.06 ug.mL-1 10.1128/aac.01047-08
Citrobacter koseri Citrobacter koseri MIC90 0.25 ug.mL-1 10.1128/aac.01047-08
Clostridioides difficile Clostridioides difficile Activity 1.0 % 10.1128/aac.00476-08
Clostridioides difficile Clostridioides difficile Activity nan None 10.1128/aac.00910-07
Clostridioides difficile Clostridioides difficile Activity nan None 10.1128/aac.01582-06
Clostridioides difficile Clostridioides difficile MIC 16.0 ug.mL-1 10.1128/aac.00476-08
Clostridioides difficile Clostridioides difficile MIC 16.0 ug.mL-1 10.1128/aac.01582-06
Clostridioides difficile Clostridioides difficile MIC 32.0 ug.mL-1 10.1128/aac.00910-07
Clostridioides difficile Clostridioides difficile MIC 32.0 ug.mL-1 10.1128/aac.01582-06
Clostridioides difficile Clostridioides difficile MIC 64.0 ug.mL-1 10.1128/aac.01582-06
Clostridioides difficile Clostridioides difficile MIC nan None 10.1016/j.bmc.2020.115776
Clostridioides difficile Clostridioides difficile MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Clostridioides difficile Clostridioides difficile MIC50 32.0 ug.mL-1 10.1128/aac.00476-08
Clostridioides difficile Clostridioides difficile MIC50 64.0 ug.mL-1 10.1128/aac.00910-07
Clostridioides difficile Clostridioides difficile MIC90 64.0 ug.mL-1 10.1128/aac.00910-07
Clostridioides difficile Clostridioides difficile MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Clostridioides difficile Clostridioides difficile MIC90 128.0 ug.mL-1 10.1128/aac.00476-08
Clostridium butyricum Clostridium butyricum MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Clostridium butyricum Clostridium butyricum MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Clostridium cadaveris Clostridium cadaveris MIC 4.0 ug.mL-1 10.1128/aac.00910-07
Clostridium cadaveris Clostridium cadaveris MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Clostridium cadaveris Clostridium cadaveris MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
[Clostridium] innocuum [Clostridium] innocuum MIC 8.0 ug.mL-1 10.1128/aac.00910-07
[Clostridium] innocuum [Clostridium] innocuum MIC50 8.0 ug.mL-1 10.1128/aac.01788-09
[Clostridium] innocuum [Clostridium] innocuum MIC50 16.0 ug.mL-1 10.1128/aac.00910-07
[Clostridium] innocuum [Clostridium] innocuum MIC90 16.0 ug.mL-1 10.1128/aac.01788-09
Clostridium paraputrificum Clostridium paraputrificum MIC 4.0 ug.mL-1 10.1128/aac.00910-07
Clostridium paraputrificum Clostridium paraputrificum MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Clostridium paraputrificum Clostridium paraputrificum MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Clostridium perfringens Clostridium perfringens MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Clostridium perfringens Clostridium perfringens MIC 2.0 ug.mL-1 10.1128/aac.00910-07
Clostridium perfringens Clostridium perfringens MIC50 0.5 ug.mL-1 10.1128/aac.01788-09
Clostridium perfringens Clostridium perfringens MIC50 2.0 ug.mL-1 10.1128/aac.00910-07
Clostridium perfringens Clostridium perfringens MIC90 2.0 ug.mL-1 10.1128/aac.01788-09
Clostridium perfringens Clostridium perfringens MIC90 4.0 ug.mL-1 10.1128/aac.00910-07
Clostridium tertium Clostridium tertium MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Clostridium tertium Clostridium tertium MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Collinsella aerofaciens Collinsella aerofaciens MIC50 0.5 ug.mL-1 10.1128/aac.01788-09
Collinsella aerofaciens Collinsella aerofaciens MIC90 2.0 ug.mL-1 10.1128/aac.01788-09
Corynebacterium jeikeium Corynebacterium jeikeium MIC 4.0 ug.mL-1 10.1128/aac.01021-08
Corynebacterium jeikeium Corynebacterium jeikeium MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Corynebacterium jeikeium Corynebacterium jeikeium MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Cutibacterium acnes Cutibacterium acnes MIC50 0.015 ug.mL-1 10.1128/aac.01788-09
Cutibacterium acnes Cutibacterium acnes MIC90 0.06 ug.mL-1 10.1128/aac.01788-09
Cyberlindnera jadinii Cyberlindnera jadinii MIC 15.62 ug.mL-1 10.1007/s00044-009-9279-4
Edwardsiella ictaluri Edwardsiella ictaluri MIC 32.0 ug.mL-1 10.1128/aac.01312-08
Eggerthella lenta Eggerthella lenta MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Eggerthella lenta Eggerthella lenta MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Enterobacter cloacae Enterobacter cloacae Activity 0.0 % 10.1128/aac.00149-08
Enterobacter cloacae Enterobacter cloacae Activity 0.0 % 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae Activity 3.5 % 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae Activity 4.7 % 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae Activity 5.9 % 10.1128/aac.01538-07
Enterobacter cloacae Enterobacter cloacae Activity 6.8 % 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae Activity 8.6 % 10.1128/aac.00149-08
Enterobacter cloacae Enterobacter cloacae Activity 10.2 % 10.1128/aac.01538-07
Enterobacter cloacae Enterobacter cloacae Activity 13.9 % 10.1128/aac.01538-07
Enterobacter cloacae Enterobacter cloacae Activity 25.0 % 10.1128/aac.01538-07
Enterobacter cloacae Enterobacter cloacae Activity 29.2 % 10.1128/aac.01538-07
Enterobacter cloacae Enterobacter cloacae Activity 48.0 % 10.1128/aac.00426-09
Enterobacter cloacae Enterobacter cloacae Activity 64.0 % 10.1128/aac.01808-09
Enterobacter cloacae Enterobacter cloacae Activity 91.9 % 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae Activity 93.2 % 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae Activity 98.0 % 10.1128/aac.00149-08
Enterobacter cloacae Enterobacter cloacae MIC 0.015 ug.mL-1 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae MIC 0.03 ug.mL-1 10.1128/aac.00336-08
Enterobacter cloacae Enterobacter cloacae MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Enterobacter cloacae Enterobacter cloacae MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Enterobacter cloacae Enterobacter cloacae MIC 0.06 ug.mL-1 10.1128/aac.01021-08
Enterobacter cloacae Enterobacter cloacae MIC 0.12 ug.mL-1 10.1128/aac.01197-09
Enterobacter cloacae Enterobacter cloacae MIC 0.5 ug.mL-1 10.1021/jm950886v
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1128/aac.00149-08
Enterobacter cloacae Enterobacter cloacae MIC 4.0 ug.mL-1 10.1128/aac.01047-08
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.00931-08
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.8b00790
Enterobacter cloacae Enterobacter cloacae MIC50 0.12 ug.mL-1 10.1128/aac.00149-08
Enterobacter cloacae Enterobacter cloacae MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Enterobacter cloacae Enterobacter cloacae MIC50 0.25 ug.mL-1 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae MIC50 0.25 ug.mL-1 10.1128/aac.01021-08
Enterobacter cloacae Enterobacter cloacae MIC50 0.5 ug.mL-1 10.1128/aac.01047-08
Enterobacter cloacae Enterobacter cloacae MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Enterobacter cloacae Enterobacter cloacae MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Enterobacter cloacae Enterobacter cloacae MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Enterobacter cloacae Enterobacter cloacae MIC50 64.0 ug.mL-1 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae MIC90 0.5 ug.mL-1 10.1128/aac.01021-08
Enterobacter cloacae Enterobacter cloacae MIC90 1.0 ug.mL-1 10.1128/aac.00149-08
Enterobacter cloacae Enterobacter cloacae MIC90 4.0 ug.mL-1 10.1128/aac.00381-08
Enterobacter cloacae Enterobacter cloacae MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Enterobacter cloacae Enterobacter cloacae MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Enterobacter cloacae Enterobacter cloacae MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Enterobacter cloacae Enterobacter cloacae MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Enterobacter cloacae Enterobacter cloacae MIC90 64.0 ug.mL-1 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae Activity 0.0 % 10.1128/aac.00149-08
Enterobacteriaceae Enterobacteriaceae Activity 0.3 % 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae Activity 0.4 % 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae Activity 7.0 % 10.1128/aac.01808-09
Enterobacteriaceae Enterobacteriaceae Activity 7.6 % 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae Activity 13.2 % 10.1128/aac.00149-08
Enterobacteriaceae Enterobacteriaceae Activity 26.9 % 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae Activity 65.4 % 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae Activity 98.0 % 10.1128/aac.00149-08
Enterobacteriaceae Enterobacteriaceae Activity 99.3 % 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae MIC 0.015 ug.mL-1 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Enterobacteriaceae Enterobacteriaceae MIC 0.25 ug.mL-1 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae MIC50 0.03 ug.mL-1 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Enterobacteriaceae Enterobacteriaceae MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Enterobacteriaceae Enterobacteriaceae MIC50 64.0 ug.mL-1 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae MIC90 0.25 ug.mL-1 10.1128/aac.00149-08
Enterobacteriaceae Enterobacteriaceae MIC90 0.25 ug.mL-1 10.1128/aac.00381-08
Enterobacteriaceae Enterobacteriaceae MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Enterobacteriaceae Enterobacteriaceae MIC90 64.0 ug.mL-1 10.1128/aac.00381-08
Enterobacter sp. Enterobacter sp. MIC50 0.12 ug.mL-1 10.1128/aac.01315-06
Enterobacter sp. Enterobacter sp. MIC90 64.0 ug.mL-1 10.1128/aac.01315-06
Enterocloster clostridioformis Enterocloster clostridioformis MIC 64.0 ug.mL-1 10.1128/aac.00910-07
Enterocloster clostridioformis Enterocloster clostridioformis MIC50 4.0 ug.mL-1 10.1128/aac.01788-09
Enterocloster clostridioformis Enterocloster clostridioformis MIC90 32.0 ug.mL-1 10.1128/aac.01788-09
Enterococcus Enterococcus Activity nan None 10.1128/aac.00355-06
Enterococcus Enterococcus MIC 10000.0 ug.mL-1 10.1128/aac.00355-06
Enterococcus Enterococcus MIC50 128.0 ug.mL-1 10.1021/jm0580510
Enterococcus Enterococcus MIC90 128.0 ug.mL-1 10.1021/jm0580510
Enterococcus durans Enterococcus durans IC50 500000.0 nM 10.1021/jm950886v
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1128/aac.01021-08
Enterococcus faecalis Enterococcus faecalis MIC 4.0 ug.mL-1 10.1021/jm8000136
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC 16.0 ug.mL-1 10.1016/s0960-894x(01)00802-2
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1021/jm950886v
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1128/aac.01021-08
Enterococcus faecalis Enterococcus faecalis MIC50 32.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Enterococcus faecalis Enterococcus faecalis MIC90 32.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Enterococcus faecium Enterococcus faecium MIC 0.5 ug.mL-1 10.1128/aac.01021-08
Enterococcus faecium Enterococcus faecium MIC 2.0 ug.mL-1 10.1074/jbc.m704286200
Enterococcus faecium Enterococcus faecium MIC 4.0 ug.mL-1 10.1021/jm8000136
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1128/aac.01021-08
Enterococcus faecium Enterococcus faecium MIC 64.0 ug.mL-1 10.1128/aac.01790-09
Enterococcus faecium Enterococcus faecium MIC 128.0 ug.mL-1 10.1021/jm8000136
Enterococcus faecium Enterococcus faecium MIC 128.0 ug.mL-1 10.1074/jbc.m704286200
Enterococcus faecium Enterococcus faecium MIC 512.0 ug.mL-1 10.1016/j.bmc.2021.116128
Enterococcus faecium Enterococcus faecium MIC50 32.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Enterococcus faecium Enterococcus faecium MIC90 32.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Enterococcus sp. Enterococcus sp. Activity nan None 10.1128/aac.01538-07
Escherichia coli Beta-lactamase SHV-1 Activity 2314.0 M min-1 (M of enzyme)-1 10.1021/jm950886v
Escherichia coli Beta-lactamase SHV-1 Activity 3339.0 M min-1 (M of enzyme)-1 10.1021/jm950886v
Escherichia coli Beta-lactamase SHV-11 Kcat 0.01 /s 10.1128/aac.00387-08
Escherichia coli Beta-lactamase SHV-11 Kcat/Km 0.35 /uM/s 10.1128/aac.00387-08
Escherichia coli Beta-lactamase SHV-11 Km 300000.0 nM 10.1128/aac.00387-08
Escherichia coli Beta-lactamase TEM Activity 79.0 M min-1 (M of enzyme)-1 10.1021/jm950886v
Escherichia coli Beta-lactamase TEM Activity 643.0 M min-1 (M of enzyme)-1 10.1021/jm950886v
Escherichia coli Cell shape peptidoglycan synthetase penicillin-binding protein 2 IC50 0.2 ug.mL-1 10.1128/aac.00029-07
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.00149-08
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.00551-10
Escherichia coli Escherichia coli Activity 0.2 % 10.1128/aac.00381-08
Escherichia coli Escherichia coli Activity 1.1 % 10.1128/aac.00381-08
Escherichia coli Escherichia coli Activity 1.7 % 10.1128/aac.01538-07
Escherichia coli Escherichia coli Activity 2.5 % 10.1128/aac.01538-07
Escherichia coli Escherichia coli Activity 2.7 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 3.3 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 3.7 % 10.1128/aac.01538-07
Escherichia coli Escherichia coli Activity 4.0 % 10.1128/aac.00426-09
Escherichia coli Escherichia coli Activity 4.2 % 10.1128/aac.01538-07
Escherichia coli Escherichia coli Activity 5.5 % 10.1128/aac.01538-07
Escherichia coli Escherichia coli Activity 5.6 % 10.1128/aac.01176-07
Escherichia coli Escherichia coli Activity 9.5 % 10.1128/aac.00149-08
Escherichia coli Escherichia coli Activity 11.1 % 10.1128/aac.01176-07
Escherichia coli Escherichia coli Activity 13.3 % 10.1128/aac.00381-08
Escherichia coli Escherichia coli Activity 20.0 % 10.1128/aac.00381-08
Escherichia coli Escherichia coli Activity 20.0 % 10.1128/aac.01076-09
Escherichia coli Escherichia coli Activity 21.7 % 10.1128/aac.01076-09
Escherichia coli Escherichia coli Activity 38.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 44.4 % 10.1128/aac.01176-07
Escherichia coli Escherichia coli Activity 66.7 % 10.1128/aac.00381-08
Escherichia coli Escherichia coli Activity 83.3 % 10.1128/aac.01176-07
Escherichia coli Escherichia coli Activity 95.8 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 96.0 % 10.1128/aac.00426-09
Escherichia coli Escherichia coli Activity 96.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 97.4 % 10.1128/aac.00149-08
Escherichia coli Escherichia coli Activity 98.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 98.3 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 98.7 % 10.1128/aac.00381-08
Escherichia coli Escherichia coli Activity 100.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00427-08
Escherichia coli Escherichia coli EC50 0.027 ug.mL-1 10.1128/aac.00427-08
Escherichia coli Escherichia coli EC50 0.057 ug.mL-1 10.1128/aac.00427-08
Escherichia coli Escherichia coli EC50 1.096 ug.mL-1 10.1128/aac.00427-08
Escherichia coli Escherichia coli IC50 290.0 nM 10.1021/jm950886v
Escherichia coli Escherichia coli IZ 16.0 mm 10.1007/s00044-009-9178-8
Escherichia coli Escherichia coli Kkmax 6.34 /hr 10.1128/aac.00427-08
Escherichia coli Escherichia coli Ks 2.4 /hr 10.1128/aac.00427-08
Escherichia coli Escherichia coli MBC 0.5 ug ml-1 10.1016/j.bmcl.2013.12.002
Escherichia coli Escherichia coli MBC 64.0 ug ml-1 10.1016/j.bmcl.2013.12.002
Escherichia coli Escherichia coli MIC 0.01 ug.mL-1 10.1016/s0960-894x(01)00802-2
Escherichia coli Escherichia coli MIC 0.015 ug.mL-1 10.1016/j.ejmech.2012.03.008
Escherichia coli Escherichia coli MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Escherichia coli Escherichia coli MIC 0.015 ug.mL-1 10.1128/aac.00381-08
Escherichia coli Escherichia coli MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01607-08
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01783-09
Escherichia coli Escherichia coli MIC 0.032 ug.mL-1 10.1128/aac.00239-09
Escherichia coli Escherichia coli MIC 0.047 ug.mL-1 10.1128/aac.00780-06
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1016/s0960-894x(01)00802-2
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1021/jm950886v
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00029-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00736-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01152-06
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01581-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01783-09
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00239-09
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00427-08
Escherichia coli Escherichia coli MIC 0.094 ug.mL-1 10.1128/aac.00239-09
Escherichia coli Escherichia coli MIC 0.094 ug.mL-1 10.1128/aac.01053-06
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.02.002
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01336-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01607-08
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1016/j.ejmech.2016.09.015
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01539-07
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01581-08
Escherichia coli Escherichia coli MIC 0.15 ug.mL-1 10.1128/aac.00381-08
Escherichia coli Escherichia coli MIC 0.19 ug.mL-1 10.1128/aac.00167-07
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.8b00790
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00858-10
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01312-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.bmcl.2013.12.002
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00460-10
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00149-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00158-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00299-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01790-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01818-09
Escherichia coli Escherichia coli MIC 1.613 ug.mL-1 10.1007/s00044-011-9607-3
Escherichia coli Escherichia coli MIC 1.613 ug.mL-1 10.1007/s00044-011-9796-9
Escherichia coli Escherichia coli MIC 1.613 ug.mL-1 10.1016/j.ejmech.2010.02.040
Escherichia coli Escherichia coli MIC 1.613 ug.mL-1 10.1016/j.ejmech.2010.07.048
Escherichia coli Escherichia coli MIC 1.613 ug.mL-1 10.1016/j.ejmech.2010.09.015
Escherichia coli Escherichia coli MIC 1.613 ug.mL-1 10.1016/j.ejmech.2012.12.057
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2012.09.095
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00427-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00460-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1016/j.ejmech.2012.02.002
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00460-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00858-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01047-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01336-09
Escherichia coli Escherichia coli MIC 5.0 ug.mL-1 10.1007/s00044-009-9178-8
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/acs.jnatprod.9b00305
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/acs.jnatprod.9b01000
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00158-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00460-10
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00780-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00858-10
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01047-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01053-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00167-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.bmcl.2013.12.002
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00460-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01047-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01312-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01539-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01586-08
Escherichia coli Escherichia coli MIC 60.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.8b00790
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01053-06
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01359-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 125.0 ug.mL-1 10.1007/s00044-009-9279-4
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00225-10
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01586-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00736-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01539-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01581-08
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 1024.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 2048.0 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 16000.0 ug.mL-1 10.1016/j.bmc.2021.116128
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.01011-08
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.01472-06
Escherichia coli Escherichia coli MIC50 0.03 ug.mL-1 10.1128/aac.00381-08
Escherichia coli Escherichia coli MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Escherichia coli Escherichia coli MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Escherichia coli Escherichia coli MIC50 0.06 ug.mL-1 10.1128/aac.01021-08
Escherichia coli Escherichia coli MIC50 0.06 ug.mL-1 10.1128/aac.01047-08
Escherichia coli Escherichia coli MIC50 0.06 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC50 0.06 ug.mL-1 10.1128/aac.01315-06
Escherichia coli Escherichia coli MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Escherichia coli Escherichia coli MIC50 16.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC50 32.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Escherichia coli Escherichia coli MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Escherichia coli Escherichia coli MIC50 32.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC50 64.0 ug.mL-1 10.1128/aac.00381-08
Escherichia coli Escherichia coli MIC50 128.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC50 256.0 ug.mL-1 10.1128/aac.00171-08
Escherichia coli Escherichia coli MIC90 0.06 ug.mL-1 10.1128/aac.00381-08
Escherichia coli Escherichia coli MIC90 0.06 ug.mL-1 10.1128/aac.01047-08
Escherichia coli Escherichia coli MIC90 0.06 ug.mL-1 10.1128/aac.01315-06
Escherichia coli Escherichia coli MIC90 0.12 ug.mL-1 10.1128/aac.00149-08
Escherichia coli Escherichia coli MIC90 0.25 ug.mL-1 10.1128/aac.00336-08
Escherichia coli Escherichia coli MIC90 0.25 ug.mL-1 10.1128/aac.01021-08
Escherichia coli Escherichia coli MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC90 64.0 ug.mL-1 10.1128/aac.00381-08
Escherichia coli Escherichia coli MIC90 64.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli MIC90 64.0 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC90 256.0 ug.mL-1 10.1128/aac.00171-08
Escherichia coli Escherichia coli MIC90 256.0 ug.mL-1 10.1128/aac.01176-07
Escherichia coli Escherichia coli Ratio 1.0 None 10.1016/j.ejmech.2012.03.008
Eubacterium limosum Eubacterium limosum MIC50 0.5 ug.mL-1 10.1128/aac.01788-09
Eubacterium limosum Eubacterium limosum MIC90 2.0 ug.mL-1 10.1128/aac.01788-09
Finegoldia magna Finegoldia magna MIC 1.0 ug.mL-1 10.1128/aac.00910-07
Finegoldia magna Finegoldia magna MIC 8.0 ug.mL-1 10.1128/aac.00910-07
Finegoldia magna Finegoldia magna MIC50 4.0 ug.mL-1 10.1128/aac.01788-09
Finegoldia magna Finegoldia magna MIC50 8.0 ug.mL-1 10.1128/aac.00910-07
Finegoldia magna Finegoldia magna MIC90 8.0 ug.mL-1 10.1128/aac.00910-07
Finegoldia magna Finegoldia magna MIC90 8.0 ug.mL-1 10.1128/aac.01788-09
Fusobacterium mortiferum Fusobacterium mortiferum MIC50 0.25 ug.mL-1 10.1128/aac.00910-07
Fusobacterium mortiferum Fusobacterium mortiferum MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Fusobacterium mortiferum Fusobacterium mortiferum MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Fusobacterium mortiferum Fusobacterium mortiferum MIC90 128.0 ug.mL-1 10.1128/aac.00910-07
Fusobacterium necrophorum Fusobacterium necrophorum MIC50 0.015 ug.mL-1 10.1128/aac.01788-09
Fusobacterium necrophorum Fusobacterium necrophorum MIC50 0.125 ug.mL-1 10.1128/aac.00910-07
Fusobacterium necrophorum Fusobacterium necrophorum MIC90 0.03 ug.mL-1 10.1128/aac.01788-09
Fusobacterium necrophorum Fusobacterium necrophorum MIC90 0.5 ug.mL-1 10.1128/aac.00910-07
Fusobacterium nucleatum Fusobacterium nucleatum MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Fusobacterium nucleatum Fusobacterium nucleatum MIC 0.5 ug.mL-1 10.1016/j.bmc.2020.115776
Fusobacterium nucleatum Fusobacterium nucleatum MIC50 0.125 ug.mL-1 10.1128/aac.01788-09
Fusobacterium nucleatum Fusobacterium nucleatum MIC50 0.25 ug.mL-1 10.1128/aac.00910-07
Fusobacterium nucleatum Fusobacterium nucleatum MIC90 0.5 ug.mL-1 10.1128/aac.00910-07
Fusobacterium nucleatum Fusobacterium nucleatum MIC90 0.5 ug.mL-1 10.1128/aac.01788-09
Fusobacterium varium Fusobacterium varium MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Fusobacterium varium Fusobacterium varium MIC50 1.0 ug.mL-1 10.1128/aac.01788-09
Fusobacterium varium Fusobacterium varium MIC50 4.0 ug.mL-1 10.1128/aac.00910-07
Fusobacterium varium Fusobacterium varium MIC90 8.0 ug.mL-1 10.1128/aac.00910-07
Fusobacterium varium Fusobacterium varium MIC90 8.0 ug.mL-1 10.1128/aac.01788-09
Haemophilus influenzae Haemophilus influenzae Activity 0.0 % 10.1128/aac.01538-07
Haemophilus influenzae Haemophilus influenzae Activity 0.3 % 10.1128/aac.01538-07
Haemophilus influenzae Haemophilus influenzae Activity 100.0 % 10.1128/aac.00149-08
Haemophilus influenzae Haemophilus influenzae Activity 100.0 % 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae ED50 0.1 mg.kg-1 10.1016/j.bmc.2016.07.029
Haemophilus influenzae Haemophilus influenzae MIC 0.008 ug.mL-1 10.1021/jm8000136
Haemophilus influenzae Haemophilus influenzae MIC 0.008 ug.mL-1 10.1128/aac.00190-07
Haemophilus influenzae Haemophilus influenzae MIC 0.008 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC 0.012 ug.mL-1 10.1128/aac.00190-07
Haemophilus influenzae Haemophilus influenzae MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Haemophilus influenzae Haemophilus influenzae MIC 0.016 ug.mL-1 10.1128/aac.00335-07
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1128/aac.01197-09
Haemophilus influenzae Haemophilus influenzae MIC 0.032 ug.mL-1 10.1128/aac.00335-07
Haemophilus influenzae Haemophilus influenzae MIC 0.06 ug.mL-1 10.1016/j.bmc.2016.07.029
Haemophilus influenzae Haemophilus influenzae MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Haemophilus influenzae Haemophilus influenzae MIC 0.06 ug.mL-1 10.1128/aac.00190-07
Haemophilus influenzae Haemophilus influenzae MIC 0.125 ug.mL-1 10.1016/j.ejmech.2016.09.015
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1016/j.ejmech.2016.09.015
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.00190-07
Haemophilus influenzae Haemophilus influenzae MIC50 0.008 ug.mL-1 10.1128/aac.01315-06
Haemophilus influenzae Haemophilus influenzae MIC50 0.015 ug.mL-1 10.1128/aac.01021-08
Haemophilus influenzae Haemophilus influenzae MIC50 0.03 ug.mL-1 10.1128/aac.01047-08
Haemophilus influenzae Haemophilus influenzae MIC50 0.03 ug.mL-1 10.1128/aac.01197-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.06 ug.mL-1 10.1021/jm0580510
Haemophilus influenzae Haemophilus influenzae MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Haemophilus influenzae Haemophilus influenzae MIC50 0.12 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.12 ug.mL-1 10.1128/aac.01021-08
Haemophilus influenzae Haemophilus influenzae MIC50 0.25 ug.mL-1 10.1128/aac.00192-09
Haemophilus influenzae Haemophilus influenzae MIC90 0.015 ug.mL-1 10.1128/aac.01021-08
Haemophilus influenzae Haemophilus influenzae MIC90 0.015 ug.mL-1 10.1128/aac.01315-06
Haemophilus influenzae Haemophilus influenzae MIC90 0.03 ug.mL-1 10.1128/aac.01047-08
Haemophilus influenzae Haemophilus influenzae MIC90 0.03 ug.mL-1 10.1128/aac.01197-09
Haemophilus influenzae Haemophilus influenzae MIC90 0.06 ug.mL-1 10.1128/aac.00149-08
Haemophilus influenzae Haemophilus influenzae MIC90 0.12 ug.mL-1 10.1021/jm0580510
Haemophilus influenzae Haemophilus influenzae MIC90 0.12 ug.mL-1 10.1128/aac.01021-08
Haemophilus influenzae Haemophilus influenzae MIC90 0.25 ug.mL-1 10.1128/aac.00192-09
Haemophilus parainfluenzae Haemophilus parainfluenzae MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Haemophilus parainfluenzae Haemophilus parainfluenzae MIC50 0.03 ug.mL-1 10.1128/aac.01047-08
Haemophilus parainfluenzae Haemophilus parainfluenzae MIC90 0.03 ug.mL-1 10.1128/aac.01047-08
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-synuclein Kd 530.0 nM 10.1016/j.ejmech.2019.01.045
Homo sapiens Beta-1 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Caco-2 logPapp -6.89 None 10.1016/j.bmc.2011.03.011
Homo sapiens Caco-2 logPapp -6.88 None 10.1016/j.bmc.2009.08.022
Homo sapiens Canalicular multispecific organic anion transporter 1 Inhibition nan % 10.1124/dmd.111.041731
Homo sapiens Canalicular multispecific organic anion transporter 2 Inhibition nan % 10.1124/dmd.111.041731
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cytochrome P450 1A2 IC50 50000.0 nM 10.1124/dmd.112.048264
Homo sapiens Cytochrome P450 1A2 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C19 IC50 50000.0 nM 10.1124/dmd.112.048264
Homo sapiens Cytochrome P450 2C19 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C9 IC50 50000.0 nM 10.1124/dmd.112.048264
Homo sapiens Cytochrome P450 2C9 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2D6 IC50 50000.0 nM 10.1124/dmd.112.048264
Homo sapiens Cytochrome P450 2D6 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2J2 IC50 27400.0 nM 10.1124/dmd.112.048264
Homo sapiens Cytochrome P450 3A4 IC50 50000.0 nM 10.1124/dmd.112.048264
Homo sapiens Cytochrome P450 3A4 Inhibition nan % 10.1021/tx300075j
Homo sapiens D-amino-acid oxidase IC50 10000.0 nM 10.1021/acs.jmedchem.5b00482
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Excitatory amino acid transporter 2 EC50 10000.0 nM 10.1021/acsmedchemlett.2c00304
Homo sapiens Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Homo sapiens Absorption 1.0 % 10.1021/jm970530e
Homo sapiens Homo sapiens Activity 1.0 % 10.1016/j.ejmech.2009.11.034
Homo sapiens Homo sapiens Activity 94.5 % 10.1021/jm00092a015
Homo sapiens Homo sapiens Bound 94.0 % 10.1021/jm00066a006
Homo sapiens Homo sapiens CL 0.07 mL.min-1.kg-1 10.1124/dmd.112.049312
Homo sapiens Homo sapiens CL 0.1 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 0.26 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL 0.26 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 0.933 mL.min-1.kg-1 10.1124/dmd.112.049312
Homo sapiens Homo sapiens CL_renal 0.1 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL_renal 0.12 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 4.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens Fa 0.01 None 10.1021/jm901371v
Homo sapiens Homo sapiens F_fraction 0.0 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fg 1.0 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fh 0.99 None 10.1021/jm901371v
Homo sapiens Homo sapiens Vdss 0.085 L.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens Vdss 0.16 L.kg-1 10.1016/j.ejmech.2009.06.004
Homo sapiens Kappa opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Liver microsomes Activity nan None 10.1021/tx300075j
Homo sapiens Liver microsomes Stability nan % 10.1021/tx300075j
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Motilin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Multidrug resistance-associated protein 4 Inhibition nan % 10.1124/dmd.111.041731
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Oligopeptide transporter small intestine isoform Ki 30000000.0 nM 10.1016/j.ejpb.2004.07.008
Homo sapiens Oligopeptide transporter small intestine isoform Ki 30000000.0 nM 10.1021/jm048982w
Homo sapiens Peroxisome proliferator-activated receptor gamma AC50 1400.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Peroxisome proliferator-activated receptor gamma AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Plasma PPB 60.0 % 10.1128/aac.00427-08
Homo sapiens Plasma PPB 76.8 % 10.1128/aac.00427-08
Homo sapiens Plasma PPB 83.0 % 10.1128/aac.00427-08
Homo sapiens Plasma PPB 90.0 % 10.1128/aac.00427-08
Homo sapiens Pregnane X receptor AC50 620.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Pregnane X receptor AC50 1600.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 23000.1 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serum PPB 92.6 % 10.1128/aac.00271-10
Homo sapiens Serum albumin PPB 56.9 % 10.1128/aac.00427-08
Homo sapiens Sodium channel protein type V alpha subunit AC50 50000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Solute carrier family 22 member 11 Ki 2380.0 nM 10.1016/s0014-2999(02)01306-7
Homo sapiens Solute carrier family 22 member 6 Ki 230.0 nM 10.1016/s0014-2999(02)01306-7
Homo sapiens Solute carrier family 22 member 8 Ki 4390.0 nM 10.1016/s0014-2999(02)01306-7
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Voltage-gated L-type calcium channel IC50 153800.0 nM 10.1038/srep02100
Homo sapiens Voltage-gated L-type calcium channel alpha-1C subunit AC50 50000.0 nM 10.1038/s41467-023-40064-9
Hoylesella loescheii Hoylesella loescheii MIC50 1.0 ug.mL-1 10.1128/aac.01788-09
Hoylesella loescheii Hoylesella loescheii MIC90 8.0 ug.mL-1 10.1128/aac.01788-09
Klebsiella aerogenes Klebsiella aerogenes Activity 55.0 % 10.1128/aac.00426-09
Klebsiella aerogenes Klebsiella aerogenes Activity 79.0 % 10.1128/aac.01808-09
Klebsiella aerogenes Klebsiella aerogenes MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Klebsiella aerogenes Klebsiella aerogenes MIC 0.03 ug.mL-1 10.1128/aac.01021-08
Klebsiella aerogenes Klebsiella aerogenes MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Klebsiella aerogenes Klebsiella aerogenes MIC 4.0 ug.mL-1 10.1128/aac.01047-08
Klebsiella aerogenes Klebsiella aerogenes MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Klebsiella aerogenes Klebsiella aerogenes MIC50 0.12 ug.mL-1 10.1128/aac.01021-08
Klebsiella aerogenes Klebsiella aerogenes MIC50 0.12 ug.mL-1 10.1128/aac.01047-08
Klebsiella aerogenes Klebsiella aerogenes MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Klebsiella aerogenes Klebsiella aerogenes MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Klebsiella aerogenes Klebsiella aerogenes MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Klebsiella aerogenes Klebsiella aerogenes MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella oxytoca Klebsiella oxytoca Activity 9.0 % 10.1128/aac.00426-09
Klebsiella oxytoca Klebsiella oxytoca Activity 89.0 % 10.1128/aac.01808-09
Klebsiella oxytoca Klebsiella oxytoca Activity 97.0 % 10.1128/aac.00426-09
Klebsiella oxytoca Klebsiella oxytoca MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Klebsiella oxytoca Klebsiella oxytoca MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Klebsiella oxytoca Klebsiella oxytoca MIC 1.0 ug.mL-1 10.1128/aac.01790-09
Klebsiella oxytoca Klebsiella oxytoca MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Klebsiella oxytoca Klebsiella oxytoca MIC50 0.06 ug.mL-1 10.1128/aac.01047-08
Klebsiella oxytoca Klebsiella oxytoca MIC90 0.12 ug.mL-1 10.1128/aac.01047-08
Klebsiella oxytoca Klebsiella oxytoca MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.0 % 10.1128/aac.00149-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.0 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.0 % 10.1128/aac.01538-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.3 % 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.4 % 10.1128/aac.01538-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 3.9 % 10.1128/aac.01538-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity 4.3 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 8.2 % 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 9.1 % 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 10.0 % 10.1128/aac.00426-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 12.1 % 10.1128/aac.00149-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 19.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 27.4 % 10.1128/aac.01076-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 32.3 % 10.1128/aac.01076-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 72.7 % 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 85.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 90.5 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 97.0 % 10.1128/aac.00426-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 98.6 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 99.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 99.3 % 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 99.5 % 10.1128/aac.00149-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity nan None 10.1128/aac.00194-07
Klebsiella pneumoniae Klebsiella pneumoniae Activity nan None 10.1128/aac.00355-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01381-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01021-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01197-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01381-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01047-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1021/acs.jmedchem.8b00790
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.8b00790
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1021/acs.jnatprod.7b00077
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.9b00305
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00010-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00194-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00355-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.8b00790
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1021/acs.jnatprod.9b01000
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00299-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01047-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01047-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 24.0 ug.mL-1 10.1128/aac.00167-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00158-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01284-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.8b00790
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00158-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00299-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01818-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 78.0 ug.mL-1 10.1128/aac.00194-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00736-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01053-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01539-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8192.0 ug.mL-1 10.1016/j.bmc.2021.116128
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.01021-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.01047-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.00336-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 16.0 ug.mL-1 10.1128/aac.01315-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 64.0 ug.mL-1 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 256.0 ug.mL-1 10.1128/aac.00171-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 0.12 ug.mL-1 10.1128/aac.00149-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 0.12 ug.mL-1 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 0.12 ug.mL-1 10.1128/aac.01021-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 0.12 ug.mL-1 10.1128/aac.01047-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.01315-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.00381-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 256.0 ug.mL-1 10.1128/aac.00171-08
Lacrimispora sphenoides Lacrimispora sphenoides MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Lacrimispora sphenoides Lacrimispora sphenoides MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Lacticaseibacillus casei Lacticaseibacillus casei MIC50 32.0 ug.mL-1 10.1128/aac.01788-09
Lacticaseibacillus casei Lacticaseibacillus casei MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Lacticaseibacillus rhamnosus Lacticaseibacillus rhamnosus MIC50 32.0 ug.mL-1 10.1128/aac.01788-09
Lacticaseibacillus rhamnosus Lacticaseibacillus rhamnosus MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Listeria monocytogenes Listeria monocytogenes MIC 1.0 ug.mL-1 10.1128/aac.01790-09
Listeria monocytogenes Listeria monocytogenes MIC 8.0 ug.mL-1 10.1128/aac.01021-08
Listeria monocytogenes Listeria monocytogenes MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Listeria monocytogenes Listeria monocytogenes MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Mammaliicoccus lentus Mammaliicoccus lentus MIC 2.0 ug.mL-1 10.1128/aac.00356-10
Micrococcus luteus Micrococcus luteus MIC 16.0 ug.mL-1 10.1128/aac.01790-09
Moraxella catarrhalis Moraxella catarrhalis Activity 100.0 % 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Moraxella catarrhalis Moraxella catarrhalis MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Moraxella catarrhalis Moraxella catarrhalis MIC 0.25 ug.mL-1 10.1021/jm8000136
Moraxella catarrhalis Moraxella catarrhalis MIC 0.25 ug.mL-1 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC 1.0 ug.mL-1 10.1016/j.ejmech.2016.09.015
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.03 ug.mL-1 10.1128/aac.01047-08
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.25 ug.mL-1 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.5 ug.mL-1 10.1128/aac.01021-08
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.5 ug.mL-1 10.1128/aac.01315-06
Moraxella catarrhalis Moraxella catarrhalis MIC90 0.5 ug.mL-1 10.1128/aac.01047-08
Moraxella catarrhalis Moraxella catarrhalis MIC90 1.0 ug.mL-1 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC90 1.0 ug.mL-1 10.1128/aac.01021-08
Moraxella catarrhalis Moraxella catarrhalis MIC90 1.0 ug.mL-1 10.1128/aac.01315-06
Morganella morganii Morganella morganii Activity 0.0 % 10.1128/aac.00149-08
Morganella morganii Morganella morganii Activity 100.0 % 10.1128/aac.00149-08
Morganella morganii Morganella morganii MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Morganella morganii Morganella morganii MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Morganella morganii Morganella morganii MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Morganella morganii Morganella morganii MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Morganella morganii Morganella morganii MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
Morganella morganii Morganella morganii MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Morganella morganii Morganella morganii MIC50 0.06 ug.mL-1 10.1128/aac.01047-08
Morganella morganii Morganella morganii MIC50 0.5 ug.mL-1 10.1128/aac.01021-08
Morganella morganii Morganella morganii MIC90 1.0 ug.mL-1 10.1128/aac.00149-08
Morganella morganii Morganella morganii MIC90 8.0 ug.mL-1 10.1128/aac.01047-08
Morganella morganii Morganella morganii MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Morganella morganii Morganella morganii MIC90 128.0 ug.mL-1 10.1128/aac.00336-08
Mus musculus Monoamine oxidase A Activity nan None 10.1021/jm800656v
Mus musculus Mus musculus Drug uptake 93.8 ug/g 10.1128/aac.00355-06
Mus musculus Mus musculus Survival 8.0 % 10.1016/j.ejmech.2016.06.017
Mus musculus Serum Ratio 37.5 % 10.1128/aac.00271-10
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 32.0 ug.mL-1 10.1016/j.ejmech.2016.12.060
Neisseria Neisseria MIC 0.5 ug.mL-1 10.1128/aac.00306-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 0.0 % 10.1128/aac.00235-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 0.0 % 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 100.0 % 10.1128/aac.00235-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 100.0 % 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity nan None 10.1128/aac.00235-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.001 ug.mL-1 10.1021/acsmedchemlett.2c00111
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.002 ug.mL-1 10.1021/acsmedchemlett.2c00111
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.002 ug.mL-1 10.1128/aac.00482-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.002 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.004 ug.mL-1 10.1021/acsmedchemlett.2c00111
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.004 ug.mL-1 10.1128/aac.00245-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.008 ug.mL-1 10.1021/acsmedchemlett.2c00111
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.008 ug.mL-1 10.1128/aac.00245-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.008 ug.mL-1 10.1128/aac.00406-09
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.016 ug.mL-1 10.1128/aac.00245-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.023 ug.mL-1 10.1128/aac.00482-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.03 ug.mL-1 10.1128/aac.00406-09
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.032 ug.mL-1 10.1128/aac.00245-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.032 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.06 ug.mL-1 10.1128/aac.00306-07
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.06 ug.mL-1 10.1128/aac.00406-09
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.063 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.064 ug.mL-1 10.1128/aac.00198-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.064 ug.mL-1 10.1128/aac.00245-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.064 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.094 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.12 ug.mL-1 10.1128/aac.00306-07
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.125 ug.mL-1 10.1128/aac.00198-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.125 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.125 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 1.0 ug.mL-1 10.1021/acsmedchemlett.2c00111
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC50 0.004 ug.mL-1 10.1128/aac.01315-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC50 0.03 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC90 0.03 ug.mL-1 10.1128/aac.01315-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC90 0.06 ug.mL-1 10.1128/aac.00788-10
Neisseria meningitidis Neisseria meningitidis Activity 0.0 % 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis Activity 100.0 % 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis Activity 100.0 % 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis MIC 0.002 ug.mL-1 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC 0.015 ug.mL-1 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis MIC50 0.002 ug.mL-1 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC50 0.015 ug.mL-1 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis MIC90 0.002 ug.mL-1 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC90 0.015 ug.mL-1 10.1128/aac.01812-09
Paeniclostridium sordellii Paeniclostridium sordellii MIC 0.25 ug.mL-1 10.1128/aac.00910-07
Paeniclostridium sordellii Paeniclostridium sordellii MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Paeniclostridium sordellii Paeniclostridium sordellii MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Parabacteroides distasonis Parabacteroides distasonis MIC 1.0 ug.mL-1 10.1128/aac.00910-07
Parabacteroides distasonis Parabacteroides distasonis MIC50 8.0 ug.mL-1 10.1128/aac.00910-07
Parabacteroides distasonis Parabacteroides distasonis MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Parabacteroides distasonis Parabacteroides distasonis MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Parabacteroides distasonis Parabacteroides distasonis MIC90 128.0 ug.mL-1 10.1128/aac.00910-07
Parabacteroides merdae Parabacteroides merdae MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Parabacteroides merdae Parabacteroides merdae MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Paraclostridium bifermentans Paraclostridium bifermentans MIC 0.25 ug.mL-1 10.1128/aac.00910-07
Paraclostridium bifermentans Paraclostridium bifermentans MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Paraclostridium bifermentans Paraclostridium bifermentans MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Parvimonas micra Parvimonas micra MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Parvimonas micra Parvimonas micra MIC50 0.125 ug.mL-1 10.1128/aac.00910-07
Parvimonas micra Parvimonas micra MIC50 0.5 ug.mL-1 10.1128/aac.01788-09
Parvimonas micra Parvimonas micra MIC90 1.0 ug.mL-1 10.1128/aac.00910-07
Parvimonas micra Parvimonas micra MIC90 1.0 ug.mL-1 10.1128/aac.01788-09
Pasteurella multocida Pasteurella multocida Activity 100.0 % 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida MIC 0.015 ug.mL-1 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida MIC50 0.015 ug.mL-1 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida MIC90 0.015 ug.mL-1 10.1128/aac.00149-08
Pasteurella sp. Pasteurella sp. Activity 15.0 % 10.1128/aac.01808-09
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 0.125 ug.mL-1 10.1128/aac.00910-07
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 0.125 ug.mL-1 10.1128/aac.01788-09
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 0.25 ug.mL-1 10.1128/aac.01788-09
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 1.0 ug.mL-1 10.1128/aac.00910-07
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.5 ug.mL-1 10.1016/j.bmc.2020.115776
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.5 ug.mL-1 10.1128/aac.00910-07
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.5 ug.mL-1 10.1128/aac.00910-07
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 8.0 ug.mL-1 10.1128/aac.01788-09
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 16.0 ug.mL-1 10.1128/aac.00910-07
Phocaeicola vulgatus Phocaeicola vulgatus MIC 2.0 ug.mL-1 10.1128/aac.00910-07
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 16.0 ug.mL-1 10.1128/aac.00910-07
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 64.0 ug.mL-1 10.1128/aac.01788-09
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 128.0 ug.mL-1 10.1128/aac.00910-07
Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC50 0.06 ug.mL-1 10.1128/aac.01788-09
Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC90 0.06 ug.mL-1 10.1128/aac.01788-09
Porphyromonas gingivalis Porphyromonas gingivalis MIC 0.12 ug.mL-1 10.1016/j.bmc.2020.115776
Porphyromonas gingivalis Porphyromonas gingivalis MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Porphyromonas levii Porphyromonas levii MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Porphyromonas somerae Porphyromonas somerae MIC50 0.015 ug.mL-1 10.1128/aac.01788-09
Porphyromonas somerae Porphyromonas somerae MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Prescottella equi Prescottella equi MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Prevotella bivia Prevotella bivia MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Prevotella bivia Prevotella bivia MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Prevotella bivia Prevotella bivia MIC50 8.0 ug.mL-1 10.1128/aac.00910-07
Prevotella bivia Prevotella bivia MIC90 64.0 ug.mL-1 10.1128/aac.00910-07
Prevotella bivia Prevotella bivia MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Prevotella buccae Prevotella buccae MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Prevotella buccae Prevotella buccae MIC50 0.25 ug.mL-1 10.1128/aac.00910-07
Prevotella buccae Prevotella buccae MIC50 0.25 ug.mL-1 10.1128/aac.01788-09
Prevotella buccae Prevotella buccae MIC90 4.0 ug.mL-1 10.1128/aac.00910-07
Prevotella buccae Prevotella buccae MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
Prevotella corporis Prevotella corporis MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Prevotella corporis Prevotella corporis MIC50 1.0 ug.mL-1 10.1128/aac.01788-09
Prevotella corporis Prevotella corporis MIC50 4.0 ug.mL-1 10.1128/aac.00910-07
Prevotella corporis Prevotella corporis MIC90 8.0 ug.mL-1 10.1128/aac.01788-09
Prevotella corporis Prevotella corporis MIC90 32.0 ug.mL-1 10.1128/aac.00910-07
Prevotella denticola Prevotella denticola MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Prevotella denticola Prevotella denticola MIC50 1.0 ug.mL-1 10.1128/aac.01788-09
Prevotella denticola Prevotella denticola MIC50 4.0 ug.mL-1 10.1128/aac.00910-07
Prevotella denticola Prevotella denticola MIC90 8.0 ug.mL-1 10.1128/aac.01788-09
Prevotella denticola Prevotella denticola MIC90 64.0 ug.mL-1 10.1128/aac.00910-07
Prevotella disiens Prevotella disiens MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Prevotella disiens Prevotella disiens MIC50 1.0 ug.mL-1 10.1128/aac.01788-09
Prevotella disiens Prevotella disiens MIC50 2.0 ug.mL-1 10.1128/aac.00910-07
Prevotella disiens Prevotella disiens MIC90 8.0 ug.mL-1 10.1128/aac.01788-09
Prevotella disiens Prevotella disiens MIC90 64.0 ug.mL-1 10.1128/aac.00910-07
Prevotella intermedia Prevotella intermedia MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Prevotella intermedia Prevotella intermedia MIC50 1.0 ug.mL-1 10.1128/aac.01788-09
Prevotella intermedia Prevotella intermedia MIC50 4.0 ug.mL-1 10.1128/aac.00910-07
Prevotella intermedia Prevotella intermedia MIC90 16.0 ug.mL-1 10.1128/aac.01788-09
Prevotella intermedia Prevotella intermedia MIC90 64.0 ug.mL-1 10.1128/aac.00910-07
Prevotella melaninogenica Prevotella melaninogenica MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Prevotella melaninogenica Prevotella melaninogenica MIC 1.0 ug.mL-1 10.1016/j.bmc.2020.115776
Prevotella melaninogenica Prevotella melaninogenica MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
Prevotella melaninogenica Prevotella melaninogenica MIC50 4.0 ug.mL-1 10.1128/aac.00910-07
Prevotella melaninogenica Prevotella melaninogenica MIC90 16.0 ug.mL-1 10.1128/aac.00910-07
Prevotella melaninogenica Prevotella melaninogenica MIC90 32.0 ug.mL-1 10.1128/aac.01788-09
Prevotella nigrescens Prevotella nigrescens MIC 0.125 ug.mL-1 10.1128/aac.00910-07
Prevotella nigrescens Prevotella nigrescens MIC50 4.0 ug.mL-1 10.1128/aac.00910-07
Prevotella nigrescens Prevotella nigrescens MIC90 16.0 ug.mL-1 10.1128/aac.00910-07
Proteus mirabilis Beta-lactamase Activity 897.0 M min-1 (M of enzyme)-1 10.1021/jm950886v
Proteus mirabilis Proteus mirabilis Activity 0.0 % 10.1128/aac.00149-08
Proteus mirabilis Proteus mirabilis Activity 0.0 % 10.1128/aac.00381-08
Proteus mirabilis Proteus mirabilis Activity 0.3 % 10.1128/aac.00381-08
Proteus mirabilis Proteus mirabilis Activity 77.0 % 10.1128/aac.00426-09
Proteus mirabilis Proteus mirabilis Activity 96.6 % 10.1128/aac.00149-08
Proteus mirabilis Proteus mirabilis Activity 99.7 % 10.1128/aac.00381-08
Proteus mirabilis Proteus mirabilis Activity 100.0 % 10.1128/aac.00381-08
Proteus mirabilis Proteus mirabilis Activity 100.0 % 10.1128/aac.01808-09
Proteus mirabilis Proteus mirabilis MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Proteus mirabilis Proteus mirabilis MIC 0.015 ug.mL-1 10.1128/aac.00381-08
Proteus mirabilis Proteus mirabilis MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Proteus mirabilis Proteus mirabilis MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Proteus mirabilis Proteus mirabilis MIC 0.03 ug.mL-1 10.1128/aac.01197-09
Proteus mirabilis Proteus mirabilis MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Proteus mirabilis Proteus mirabilis MIC 0.06 ug.mL-1 10.1128/aac.00381-08
Proteus mirabilis Proteus mirabilis MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Proteus mirabilis Proteus mirabilis MIC 1.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC 2.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC 8.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC 32.0 ug.mL-1 10.1128/aac.01399-07
Proteus mirabilis Proteus mirabilis MIC50 0.015 ug.mL-1 10.1128/aac.00336-08
Proteus mirabilis Proteus mirabilis MIC50 0.015 ug.mL-1 10.1128/aac.00381-08
Proteus mirabilis Proteus mirabilis MIC50 0.015 ug.mL-1 10.1128/aac.01021-08
Proteus mirabilis Proteus mirabilis MIC50 0.03 ug.mL-1 10.1128/aac.01047-08
Proteus mirabilis Proteus mirabilis MIC50 0.03 ug.mL-1 10.1128/aac.01197-09
Proteus mirabilis Proteus mirabilis MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Proteus mirabilis Proteus mirabilis MIC50 8.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC90 0.015 ug.mL-1 10.1128/aac.00381-08
Proteus mirabilis Proteus mirabilis MIC90 0.015 ug.mL-1 10.1128/aac.01021-08
Proteus mirabilis Proteus mirabilis MIC90 0.12 ug.mL-1 10.1128/aac.00149-08
Proteus mirabilis Proteus mirabilis MIC90 4.0 ug.mL-1 10.1128/aac.00336-08
Proteus mirabilis Proteus mirabilis MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Proteus mirabilis Proteus mirabilis MIC90 32.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Proteus vulgaris Proteus vulgaris MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Proteus vulgaris Proteus vulgaris MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Proteus vulgaris Proteus vulgaris MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Proteus vulgaris Proteus vulgaris MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Proteus vulgaris Proteus vulgaris MIC 15.62 ug.mL-1 10.1007/s00044-009-9279-4
Proteus vulgaris Proteus vulgaris MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Proteus vulgaris Proteus vulgaris MIC50 1.0 ug.mL-1 10.1128/aac.01021-08
Proteus vulgaris Proteus vulgaris MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Proteus vulgaris Proteus vulgaris MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Proteus vulgaris Proteus vulgaris MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Proteus vulgaris Proteus vulgaris MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Providencia rettgeri Providencia rettgeri MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Providencia rettgeri Providencia rettgeri MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Providencia rettgeri Providencia rettgeri MIC50 0.06 ug.mL-1 10.1128/aac.01021-08
Providencia rettgeri Providencia rettgeri MIC50 0.06 ug.mL-1 10.1128/aac.01047-08
Providencia rettgeri Providencia rettgeri MIC90 0.25 ug.mL-1 10.1128/aac.01021-08
Providencia rettgeri Providencia rettgeri MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Providencia sp. Providencia sp. Activity 0.0 % 10.1128/aac.00149-08
Providencia sp. Providencia sp. Activity 100.0 % 10.1128/aac.00149-08
Providencia sp. Providencia sp. MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Providencia sp. Providencia sp. MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Providencia sp. Providencia sp. MIC90 2.0 ug.mL-1 10.1128/aac.00149-08
Providencia stuartii Providencia stuartii MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Providencia stuartii Providencia stuartii MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Providencia stuartii Providencia stuartii MIC 0.03 ug.mL-1 10.1128/aac.01047-08
Providencia stuartii Providencia stuartii MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Providencia stuartii Providencia stuartii MIC50 0.06 ug.mL-1 10.1128/aac.01021-08
Providencia stuartii Providencia stuartii MIC50 0.06 ug.mL-1 10.1128/aac.01047-08
Providencia stuartii Providencia stuartii MIC90 0.25 ug.mL-1 10.1128/aac.01021-08
Providencia stuartii Providencia stuartii MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Providencia stuartii Providencia stuartii MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas aeruginosa Penicillin-binding protein 1B Activity nan None 10.1128/aac.00029-07
Pseudomonas aeruginosa Penicillin-binding protein 2 Activity nan None 10.1128/aac.00029-07
Pseudomonas aeruginosa Penicillin-binding protein 3 Activity nan None 10.1128/aac.00029-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 17.0 % 10.1128/aac.01808-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 19.0 % 10.1128/aac.00426-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 27.0 % 10.1128/aac.01538-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 30.0 % 10.1128/aac.01538-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 30.2 % 10.1128/aac.01538-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 33.3 % 10.1128/aac.01538-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 51.5 % 10.1128/aac.01538-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.00029-07
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 18.0 mm 10.1007/s00044-009-9178-8
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 128.0 ug ml-1 10.1016/j.bmcl.2013.12.002
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.12 ug.mL-1 10.1128/aac.00336-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jnatprod.7b00077
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.01021-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.613 ug.mL-1 10.1007/s00044-011-9607-3
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.613 ug.mL-1 10.1007/s00044-011-9796-9
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.613 ug.mL-1 10.1016/j.ejmech.2010.02.040
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.613 ug.mL-1 10.1016/j.ejmech.2010.07.048
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.613 ug.mL-1 10.1016/j.ejmech.2010.09.015
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.613 ug.mL-1 10.1016/j.ejmech.2012.12.057
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.9b00305
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1021/acs.jnatprod.9b01000
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00893-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 5.0 ug.mL-1 10.1007/s00044-009-9178-8
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.01047-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.01197-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 15.62 ug.mL-1 10.1007/s00044-009-9279-4
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1021/jm950886v
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00893-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.01021-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00893-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.01011-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.bmc.2021.116128
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.01790-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 125.0 ug.mL-1 10.1007/s00044-009-9279-4
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1016/j.bmcl.2013.12.002
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.01405-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1128/aac.01561-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 64.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 64.0 ug.mL-1 10.1128/aac.01315-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 64.0 ug.mL-1 10.1128/aac.01315-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 128.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas fluorescens Pseudomonas fluorescens Activity 15.0 % 10.1128/aac.01808-09
Pseudomonas fluorescens Pseudomonas fluorescens IZ 16.0 mm 10.1007/s00044-009-9178-8
Pseudomonas fluorescens Pseudomonas fluorescens MIC 5.0 ug.mL-1 10.1007/s00044-009-9178-8
Pseudomonas fluorescens Pseudomonas fluorescens MIC 8.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas fluorescens Pseudomonas fluorescens MIC50 32.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas fluorescens Pseudomonas fluorescens MIC90 128.0 ug.mL-1 10.1128/aac.00336-08
Pseudomonas putida Pseudomonas putida MIC 32.0 ug.mL-1 10.1128/aac.00931-08
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Oligopeptide transporter, kidney isoform Ki 20000000.0 nM 10.1016/j.ejpb.2004.07.008
Rattus norvegicus Plasma Fu 0.052 None 10.1021/jm901371v
Rattus norvegicus Plasma logFu 0.075 None 10.1016/j.ejmech.2009.06.004
Rattus norvegicus Rattus norvegicus Activity 249.0 pg/ml 10.1128/aac.01014-06
Rattus norvegicus Rattus norvegicus Activity 4578.0 pg/ml 10.1128/aac.01014-06
Rattus norvegicus Rattus norvegicus Activity nan None 10.1128/aac.00812-09
Rattus norvegicus Rattus norvegicus Bound 88.5 % 10.1021/jm00066a006
Rattus norvegicus Rattus norvegicus CL 0.82 mL.min-1.kg-1 10.1124/dmd.112.049312
Rattus norvegicus Rattus norvegicus CL 12.73 mL.min-1.kg-1 10.1124/dmd.112.049312
Rattus norvegicus Rattus norvegicus Inhibition 4.7 % 10.1128/aac.00812-09
Rattus norvegicus Serum PPB 34.0 % 10.1128/aac.00271-10
Rattus norvegicus Solute carrier family 22 member 6 Activity nan None None
Rattus norvegicus Solute carrier family 22 member 6 IC50 840000.0 nM 10.1016/s0024-3205(02)01500-x
Rattus norvegicus Solute carrier family 22 member 8 IC50 2000000.0 nM 10.1016/s0024-3205(02)01500-x
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 32.0 ug.mL-1 10.1016/s0960-894x(01)00802-2
Salmonella Salmonella MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Salmonella Salmonella MIC 4.0 ug.mL-1 10.1128/aac.00460-10
Salmonella Salmonella MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Salmonella Salmonella MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Salmonella enterica Salmonella enterica MIC 4.0 ug.mL-1 10.1128/aac.01790-09
Salmonella enterica subsp. enterica Salmonella enterica subsp. enterica MIC 16.0 ug.mL-1 10.1128/aac.00842-07
Salmonella enterica subsp. enterica serovar Enteritidis Salmonella enteritidis MIC 125.0 ug.mL-1 10.1007/s00044-009-9279-4
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 0.125 ug.mL-1 10.1128/aac.00225-10
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 128.0 ug.mL-1 10.1128/aac.00225-10
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.047 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 2.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 4.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 6.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 8.0 ug.mL-1 10.1128/aac.00460-10
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 12.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 16.0 ug.mL-1 10.1128/aac.00460-10
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 24.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 32.0 ug.mL-1 10.1128/aac.00460-10
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 64.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 64.0 ug.mL-1 10.1128/aac.00460-10
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 256.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC nan None 10.1128/aac.01472-06
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Ratio 2.0 None 10.1016/j.ejmech.2012.03.008
Salmonella sp. Salmonella sp. MIC 0.03 ug.mL-1 10.1128/aac.01021-08
Salmonella sp. Salmonella sp. MIC50 0.06 ug.mL-1 10.1128/aac.01021-08
Salmonella sp. Salmonella sp. MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Schaalia meyeri Schaalia meyeri MIC50 0.125 ug.mL-1 10.1128/aac.01788-09
Schaalia meyeri Schaalia meyeri MIC90 0.5 ug.mL-1 10.1128/aac.01788-09
Serratia marcescens Serratia marcescens Activity 0.0 % 10.1128/aac.00149-08
Serratia marcescens Serratia marcescens Activity 0.6 % 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens Activity 1.4 % 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens Activity 10.0 % 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens Activity 30.0 % 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens Activity 60.0 % 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens Activity 93.2 % 10.1128/aac.00149-08
Serratia marcescens Serratia marcescens Activity 98.1 % 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens Activity 100.0 % 10.1128/aac.01808-09
Serratia marcescens Serratia marcescens MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Serratia marcescens Serratia marcescens MIC 0.015 ug.mL-1 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Serratia marcescens Serratia marcescens MIC 0.06 ug.mL-1 10.1128/aac.01021-08
Serratia marcescens Serratia marcescens MIC 0.06 ug.mL-1 10.1128/aac.01047-08
Serratia marcescens Serratia marcescens MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.02.002
Serratia marcescens Serratia marcescens MIC 4.0 ug.mL-1 10.1128/aac.01047-08
Serratia marcescens Serratia marcescens MIC 8.0 ug.mL-1 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens MIC 32.0 ug.mL-1 10.1128/aac.01539-07
Serratia marcescens Serratia marcescens MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Serratia marcescens Serratia marcescens MIC50 0.25 ug.mL-1 10.1128/aac.00149-08
Serratia marcescens Serratia marcescens MIC50 0.25 ug.mL-1 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens MIC50 0.25 ug.mL-1 10.1128/aac.01021-08
Serratia marcescens Serratia marcescens MIC50 0.5 ug.mL-1 10.1128/aac.01047-08
Serratia marcescens Serratia marcescens MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Serratia marcescens Serratia marcescens MIC50 64.0 ug.mL-1 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens MIC90 1.0 ug.mL-1 10.1128/aac.00381-08
Serratia marcescens Serratia marcescens MIC90 2.0 ug.mL-1 10.1128/aac.01021-08
Serratia marcescens Serratia marcescens MIC90 4.0 ug.mL-1 10.1128/aac.00149-08
Serratia marcescens Serratia marcescens MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Serratia marcescens Serratia marcescens MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
Serratia marcescens Serratia marcescens MIC90 64.0 ug.mL-1 10.1128/aac.00381-08
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.07003 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Shigella Shigella MIC 0.25 ug.mL-1 10.1128/aac.00039-10
Shigella Shigella MIC 32.0 ug.mL-1 10.1128/aac.00039-10
Shigella Shigella MIC 64.0 ug.mL-1 10.1128/aac.00039-10
Shigella flexneri Shigella flexneri MIC 16.0 ug.mL-1 10.1128/aac.00039-10
Shigella flexneri Shigella flexneri MIC 32.0 ug.mL-1 10.1128/aac.00039-10
Shigella sonnei Shigella sonnei MIC 64.0 ug.mL-1 10.1128/aac.00039-10
Shigella sonnei Shigella sonnei MIC 1024.0 ug.mL-1 10.1128/aac.00227-08
Shigella sp. Shigella sp. MIC 0.03 ug.mL-1 10.1128/aac.01021-08
Shigella sp. Shigella sp. MIC50 0.03 ug.mL-1 10.1128/aac.01021-08
Shigella sp. Shigella sp. MIC90 0.06 ug.mL-1 10.1128/aac.01021-08
Shouchella clausii Shouchella clausii MIC 128000.0 ug.mL-1 10.1128/aac.00537-07
Staphylococcus Staphylococcus MIC 0.5 ug.mL-1 10.1128/aac.01021-08
Staphylococcus Staphylococcus MIC 4.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus Staphylococcus MIC 4.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus Staphylococcus MIC50 2.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus Staphylococcus MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus Staphylococcus MIC50 16.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus Staphylococcus MIC90 8.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus Staphylococcus MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus Staphylococcus MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus aureus MecA IC50 0.25 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus MecA IC50 1.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus MecA IC50 2.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus MecA IC50 50.0 ug.mL-1 10.1128/aac.00029-07
Staphylococcus aureus MecA IC50 128.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Penicillin-binding protein 1 IC50 0.5 ug.mL-1 10.1128/aac.00029-07
Staphylococcus aureus Penicillin-binding protein 2 IC50 0.1 ug.mL-1 10.1128/aac.00029-07
Staphylococcus aureus Penicillin-binding protein 3 IC50 1.0 ug.mL-1 10.1128/aac.00029-07
Staphylococcus aureus Penicillin-binding protein 4 IC50 10.0 ug.mL-1 10.1128/aac.00029-07
Staphylococcus aureus Staphylococcus aureus Activity 0.0 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 0.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 0.0 % 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus Activity 0.0 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 0.3 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 2.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 11.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 14.2 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 14.8 mg/L 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus Activity 22.1 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 27.1 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 33.1 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 97.1 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 98.0 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 98.7 % 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus Activity 100.0 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 200.0 mg/L 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/acsmedchemlett.1c00648
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.00875-07
Staphylococcus aureus Staphylococcus aureus EC50 1.83 ug.mL-1 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus ED50 3.72 mg.kg-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus ED50 100.0 mg.kg-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus FC 4.0 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus FC 16.0 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus FC 512.0 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus log10cfu -0.3 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus log10cfu 2.09 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus log10cfu 2.44 None 10.1128/aac.01135-08
Staphylococcus aureus Staphylococcus aureus MBC 4.0 ug ml-1 10.1016/j.bmcl.2013.12.002
Staphylococcus aureus Staphylococcus aureus MIC 0.003 ug.mL-1 10.1128/aac.01173-08
Staphylococcus aureus Staphylococcus aureus MIC 0.004 ug.mL-1 10.1128/aac.01173-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC 0.256 ug.mL-1 10.1128/aac.01173-08
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2012.02.002
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2012.12.024
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC 1.09 ug.mL-1 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus MIC 1.38 ug.mL-1 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2012.08.013
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.10.063
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2016.09.015
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/s0960-894x(99)00127-4
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00029-07
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 2.88 ug.mL-1 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus MIC 2.9 ug.mL-1 10.1128/aac.01325-09
Staphylococcus aureus Staphylococcus aureus MIC 3.1 ug.mL-1 10.1128/aac.01325-09
Staphylococcus aureus Staphylococcus aureus MIC 3.125 ug.mL-1 10.1007/s00044-011-9607-3
Staphylococcus aureus Staphylococcus aureus MIC 3.125 ug.mL-1 10.1007/s00044-011-9796-9
Staphylococcus aureus Staphylococcus aureus MIC 3.125 ug.mL-1 10.1016/j.ejmech.2010.02.040
Staphylococcus aureus Staphylococcus aureus MIC 3.125 ug.mL-1 10.1016/j.ejmech.2010.07.048
Staphylococcus aureus Staphylococcus aureus MIC 3.125 ug.mL-1 10.1016/j.ejmech.2010.09.015
Staphylococcus aureus Staphylococcus aureus MIC 3.125 ug.mL-1 10.1016/j.ejmech.2012.12.057
Staphylococcus aureus Staphylococcus aureus MIC 3.4 ug.mL-1 10.1128/aac.01325-09
Staphylococcus aureus Staphylococcus aureus MIC 3.5 ug.mL-1 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus MIC 3.75 ug.mL-1 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus MIC 3.88 ug.mL-1 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2013.12.002
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.ejmech.2012.02.002
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/s0960-894x(01)00802-2
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/s0960-894x(99)00127-4
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm950886v
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00594-10
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.01247-08
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 5.88 ug.mL-1 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus MIC 6.0 ug.mL-1 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.bmcl.2012.08.013
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.bmcl.2012.09.095
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.ejmech.2012.02.002
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.bmcl.2012.09.095
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2015.10.063
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/s0960-894x(01)00802-2
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/jm950886v
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus aureus Staphylococcus aureus MIC 38.8 ug.mL-1 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00029-07
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00084-09
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.01790-09
Staphylococcus aureus Staphylococcus aureus MIC 125.0 ug.mL-1 10.1007/s00044-009-9279-4
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1016/j.bmcl.2012.09.095
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1016/j.bmcl.2015.10.063
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1016/j.ejmech.2012.02.002
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1128/aac.00594-10
Staphylococcus aureus Staphylococcus aureus MIC 1024.0 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 4096.0 ug.mL-1 10.1016/j.bmc.2021.116128
Staphylococcus aureus Staphylococcus aureus MIC50 1.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC50 2.0 ug.mL-1 10.1021/jm0580510
Staphylococcus aureus Staphylococcus aureus MIC50 2.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1016/j.ejmech.2012.12.024
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus aureus Staphylococcus aureus MIC50 32.0 ug.mL-1 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus MIC50 128.0 ug.mL-1 10.1021/jm0580510
Staphylococcus aureus Staphylococcus aureus MIC90 2.0 ug.mL-1 10.1021/jm0580510
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.01325-09
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus MIC90 128.0 ug.mL-1 10.1016/j.ejmech.2012.12.024
Staphylococcus aureus Staphylococcus aureus MIC90 128.0 ug.mL-1 10.1021/jm0580510
Staphylococcus aureus Staphylococcus aureus PAE 2.3 hr 10.1128/aac.00785-09
Staphylococcus aureus Staphylococcus aureus Ratio 1.3 None 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus Ratio 1.5 None 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus Ratio 1.6 None 10.1128/aac.00271-10
Staphylococcus aureus Staphylococcus aureus Ratio 13.5 None 10.1128/aac.00271-10
Staphylococcus epidermidis Staphylococcus epidermidis Activity 0.0 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 1.8 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 8.1 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 25.0 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 100.0 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis IC50 960000.0 nM 10.1021/jm950886v
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1021/jm8000136
Staphylococcus epidermidis Staphylococcus epidermidis MIC 4.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 8.0 ug.mL-1 10.1021/jm0580510
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 32.0 ug.mL-1 10.1021/jm0580510
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 15.0 % 10.1128/aac.01808-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity nan None 10.1128/aac.00682-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MBC 128.0 ug ml-1 10.1016/j.bmcl.2013.12.002
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 0.5 ug.mL-1 10.1128/aac.01021-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 8.0 ug.mL-1 10.1128/aac.00336-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 32.0 ug.mL-1 10.1128/aac.01047-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 64.0 ug.mL-1 10.1016/j.bmcl.2013.12.002
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 128.0 ug.mL-1 10.1128/aac.00682-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 256.0 ug.mL-1 10.1128/aac.00682-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 256.0 ug.mL-1 10.1128/aac.01513-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 32.0 ug.mL-1 10.1128/aac.00336-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 32.0 ug.mL-1 10.1128/aac.01021-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 32.0 ug.mL-1 10.1128/aac.01047-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 32.0 ug.mL-1 10.1128/aac.01021-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 32.0 ug.mL-1 10.1128/aac.01047-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 128.0 ug.mL-1 10.1128/aac.00336-08
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Ratio 5.5 None 10.1128/aac.00682-07
Streptococcus Streptococcus Activity 4.3 % 10.1128/aac.01453-08
Streptococcus Streptococcus Activity 92.5 % 10.1128/aac.01453-08
Streptococcus Streptococcus Activity 99.9 % 10.1128/aac.01453-08
Streptococcus Streptococcus MIC 0.25 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC50 0.25 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC90 0.25 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC90 1.0 ug.mL-1 10.1128/aac.01453-08
Streptococcus agalactiae Streptococcus agalactiae Activity 96.0 % 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae Activity 97.6 % 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae Activity 100.0 % 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.03 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.03 ug.mL-1 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae MIC 0.06 ug.mL-1 10.1128/aac.01021-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.01021-08
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.12 ug.mL-1 10.1128/aac.01021-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.12 ug.mL-1 10.1128/aac.01197-09
Streptococcus constellatus Streptococcus constellatus Activity 0.0 % 10.1128/aac.01845-09
Streptococcus constellatus Streptococcus constellatus Activity 75.0 % 10.1128/aac.01398-07
Streptococcus constellatus Streptococcus constellatus MIC 0.03 ug.mL-1 10.1128/aac.01398-07
Streptococcus constellatus Streptococcus constellatus MIC50 nan None 10.1128/aac.01398-07
Streptococcus constellatus Streptococcus constellatus MIC90 nan None 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius Activity 0.0 % 10.1128/aac.01845-09
Streptococcus intermedius Streptococcus intermedius Activity 75.0 % 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius MIC 0.03 ug.mL-1 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius MIC50 nan None 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius MIC90 nan None 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis Activity 75.0 % 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis MIC 0.03 ug.mL-1 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis MIC50 nan None 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis MIC90 nan None 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis Activity 75.0 % 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis MIC 0.03 ug.mL-1 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis MIC50 nan None 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis MIC90 nan None 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.01538-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.1 % 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.2 % 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.26 % 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.5 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.2 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 3.4 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 5.6 % 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 6.8 % 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 7.4 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 9.0 % 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 18.4 % 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 31.3 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 43.9 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 65.5 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 65.6 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 73.0 % 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 76.2 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 77.0 % 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 79.4 % 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 80.4 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 83.3 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 92.0 % 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 95.2 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 95.3 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 97.0 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 97.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 97.1 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 97.2 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 98.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 98.3 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 98.8 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.3 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.5 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.7 % 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00943-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 2500.0 cpm/min 10.1128/aac.01000-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1021/acs.jmedchem.0c00520
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1128/aac.00427-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1128/aac.00875-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1128/aac.00943-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae EC50 0.004 ug.mL-1 10.1128/aac.00427-08
Streptococcus pneumoniae Streptococcus pneumoniae EC50 0.015 ug.mL-1 10.1128/aac.00427-08
Streptococcus pneumoniae Streptococcus pneumoniae EC50 0.084 ug.mL-1 10.1128/aac.00427-08
Streptococcus pneumoniae Streptococcus pneumoniae ED50 0.11 mg.kg-1 10.1016/j.ejmech.2016.09.015
Streptococcus pneumoniae Streptococcus pneumoniae ED50 0.22 mg.kg-1 10.1021/jm8000136
Streptococcus pneumoniae Streptococcus pneumoniae ED50 5.65 mg.kg-1 10.1016/j.ejmech.2016.09.015
Streptococcus pneumoniae Streptococcus pneumoniae ED50 27.5 mg.kg-1 10.1021/jm8000136
Streptococcus pneumoniae Streptococcus pneumoniae IC50 500.0 nM 10.1021/jm950886v
Streptococcus pneumoniae Streptococcus pneumoniae IC50 2500.0 nM 10.1021/jm950886v
Streptococcus pneumoniae Streptococcus pneumoniae IC50 5500.0 nM 10.1021/jm950886v
Streptococcus pneumoniae Streptococcus pneumoniae Kkmax 3.59 /hr 10.1128/aac.00427-08
Streptococcus pneumoniae Streptococcus pneumoniae Ks 1.56 /hr 10.1128/aac.00427-08
Streptococcus pneumoniae Streptococcus pneumoniae log10cfu 0.5 None 10.1128/aac.00943-09
Streptococcus pneumoniae Streptococcus pneumoniae log10cfu 0.8 None 10.1128/aac.00943-09
Streptococcus pneumoniae Streptococcus pneumoniae log10cfu 3.3 None 10.1128/aac.00943-09
Streptococcus pneumoniae Streptococcus pneumoniae log10cfu 4.6 None 10.1128/aac.00943-09
Streptococcus pneumoniae Streptococcus pneumoniae Log10 cfu 6.3 /ml 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae log10CFU/ml -4.04 None 10.1128/aac.01000-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.008 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.008 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.008 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.01 ug.mL-1 10.1016/s0960-894x(01)00802-2
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.01 ug.mL-1 10.1128/aac.00427-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1016/j.bmc.2016.07.029
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1016/j.ejmech.2016.09.015
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.02 ug.mL-1 10.1128/aac.00427-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.023 ug.mL-1 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/s0960-894x(99)00127-4
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00029-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1021/jm950886v
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.063 ug.mL-1 10.1021/jm8000136
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.094 ug.mL-1 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.02.002
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.16 ug.mL-1 10.1128/aac.00427-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1016/j.bmc.2020.115776
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1021/jm8000136
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01000-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1016/j.ejmech.2016.09.015
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1016/s0960-894x(99)00127-4
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1016/j.ejmech.2016.09.015
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1016/s0960-894x(99)00127-4
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1021/jm950886v
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/s0960-894x(99)00127-4
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00029-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1021/jm0580510
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.01315-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.125 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1016/j.bmc.2020.115776
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.12 ug.mL-1 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1021/jm0580510
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01315-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1016/j.bmc.2020.115776
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01021-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae PAE 0.7 hr 10.1128/aac.00785-09
Streptococcus pneumoniae Streptococcus pneumoniae PD50 0.37 mg kg-1 10.1016/j.bmc.2016.07.029
Streptococcus pneumoniae Streptococcus pneumoniae Post Antibiotic Effe 1.3 hr 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae Ratio 1.1 None 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae Ratio 1.7 None 10.1128/aac.01014-06
Streptococcus pneumoniae Streptococcus pneumoniae Ratio 1.8 None 10.1128/aac.01014-06
Streptococcus pneumoniae R6 Penicillin-binding protein 2X Activity nan None 10.1021/jm900625q
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.1 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.25 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 4.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 8.0 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 16.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 32.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x Activity nan None 10.1021/jm900625q
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.1 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 1.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 4.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae (strain ATCC BAA-255 / R6) Penicillin-binding protein 2B IC50 8.0 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae (strain ATCC BAA-255 / R6) Penicillin-binding protein 2B IC50 nan None 10.1128/aac.00590-10
Streptococcus pyogenes Streptococcus pyogenes Activity 92.0 % 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes MIC 0.016 ug.mL-1 10.1021/jm8000136
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1016/s0960-894x(99)00127-4
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.02.002
Streptococcus pyogenes Streptococcus pyogenes MIC 3.9 ug.mL-1 10.1007/s00044-009-9279-4
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.015 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.015 ug.mL-1 10.1128/aac.01021-08
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.015 ug.mL-1 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.03 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.03 ug.mL-1 10.1128/aac.01315-06
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.06 ug.mL-1 10.1021/jm0580510
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.03 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.03 ug.mL-1 10.1128/aac.01021-08
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.03 ug.mL-1 10.1128/aac.01315-06
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.06 ug.mL-1 10.1021/jm0580510
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.12 ug.mL-1 10.1128/aac.01398-07
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC 0.015 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC50 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC90 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC50 0.06 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC90 0.06 ug.mL-1 10.1128/aac.00100-07
Streptococcus viridans Streptococcus viridans Activity 0.0 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans Activity 28.6 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans Activity 75.0 % 10.1128/aac.01398-07
Streptococcus viridans Streptococcus viridans Activity 100.0 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC 0.015 ug.mL-1 10.1128/aac.00100-07
Streptococcus viridans Streptococcus viridans MIC 0.015 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC 0.015 ug.mL-1 10.1128/aac.01021-08
Streptococcus viridans Streptococcus viridans MIC 0.03 ug.mL-1 10.1128/aac.01398-07
Streptococcus viridans Streptococcus viridans MIC 0.06 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus viridans Streptococcus viridans MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC50 0.12 ug.mL-1 10.1128/aac.00100-07
Streptococcus viridans Streptococcus viridans MIC50 0.12 ug.mL-1 10.1128/aac.01021-08
Streptococcus viridans Streptococcus viridans MIC50 0.12 ug.mL-1 10.1128/aac.01315-06
Streptococcus viridans Streptococcus viridans MIC50 0.25 ug.mL-1 10.1128/aac.01197-09
Streptococcus viridans Streptococcus viridans MIC50 2.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC50 nan None 10.1128/aac.01398-07
Streptococcus viridans Streptococcus viridans MIC90 0.25 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC90 0.5 ug.mL-1 10.1128/aac.01197-09
Streptococcus viridans Streptococcus viridans MIC90 1.0 ug.mL-1 10.1128/aac.01021-08
Streptococcus viridans Streptococcus viridans MIC90 1.0 ug.mL-1 10.1128/aac.01315-06
Streptococcus viridans Streptococcus viridans MIC90 2.0 ug.mL-1 10.1128/aac.00100-07
Streptococcus viridans Streptococcus viridans MIC90 8.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC90 nan None 10.1128/aac.01398-07
Thomasclavelia ramosa Thomasclavelia ramosa MIC 0.25 ug.mL-1 10.1128/aac.00910-07
Thomasclavelia ramosa Thomasclavelia ramosa MIC50 0.25 ug.mL-1 10.1128/aac.01788-09
Thomasclavelia ramosa Thomasclavelia ramosa MIC50 0.5 ug.mL-1 10.1128/aac.00910-07
Thomasclavelia ramosa Thomasclavelia ramosa MIC90 0.5 ug.mL-1 10.1128/aac.01788-09
Veillonella Veillonella MIC50 4.0 ug.mL-1 10.1128/aac.01788-09
Veillonella Veillonella MIC90 8.0 ug.mL-1 10.1128/aac.01788-09
Yersinia enterocolitica Yersinia enterocolitica MIC 0.012 ug.mL-1 10.1128/aac.01754-09
Yersinia enterocolitica Yersinia enterocolitica MIC 0.016 ug.mL-1 10.1128/aac.01754-09
Yersinia enterocolitica Yersinia enterocolitica MIC 0.023 ug.mL-1 10.1128/aac.01754-09
None ADMET AUC 21900.0 ng.hr.mL-1 10.1016/j.ejmech.2016.09.015
None ADMET AUC 60800.0 ng.hr.mL-1 10.1016/j.ejmech.2016.09.015
None ADMET CL 0.24 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL 0.26 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET CL 0.45 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL 0.77 mL.min-1.kg-1 10.1016/j.ejmech.2016.09.015
None ADMET CL 4.0 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL 5.49 mL.min-1.kg-1 10.1016/j.ejmech.2016.09.015
None ADMET Drug excretion 30.0 % 10.1124/dmd.112.049312
None ADMET Drug excretion 62.0 % 10.1124/dmd.112.049312
None ADMET Drug excretion 63.0 % 10.1124/dmd.112.049312
None ADMET log10(%HIA +10) 1.041 None 10.1016/j.ejmech.2010.11.005
None ADMET logPapp -6.88 None 10.1124/dmd.111.041665
None ADMET MRT 5.4 hr 10.1124/dmd.108.020479
None ADMET Recovery 25.4 % 10.1021/jm00092a015
None ADMET T1/2 0.64 hr 10.1016/j.ejmech.2016.09.015
None ADMET T1/2 1.95 hr 10.1016/j.ejmech.2016.09.015
None ADMET T1/2 8.6 hr 10.1124/dmd.108.020479
None ADMET Vdss 0.085 L.kg-1 10.1124/dmd.108.020479
None ADMET Vdss 0.11 L.kg-1 10.1002/jps.20373
None ADMET Vdss 0.16 L.kg-1 10.1002/jps.20373
None ADMET Vdss 0.18 mL/min/kg 10.1002/jps.20373
None ADMET Vdss 0.24 L.kg-1 10.1002/jps.20373
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value 3.4 None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 3.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value 2.6 None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value 1.9 None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value 3.8 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value 3.8 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Molecular identity unknown Inhibition nan % 10.1128/aac.00788-09
None Molecular identity unknown PPB 94.0 % 10.1016/j.ejmech.2016.09.015
None Molecular identity unknown PPB 95.0 % 10.1016/j.ejmech.2016.09.015
None NON-PROTEIN TARGET Activity 0.0 % 10.1128/aac.01845-09
None NON-PROTEIN TARGET Activity 99.9 % 10.1128/aac.01247-08
None NON-PROTEIN TARGET Fu 0.052 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 4.6 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 30.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 71.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET MBC 0.5 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC 0.78 mg/ml 10.1128/aac.00788-09
None NON-PROTEIN TARGET MBC 1.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC 1.5 mg/ml 10.1128/aac.00788-09
None NON-PROTEIN TARGET MBC 2.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC 4.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC90 4.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.015 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC 0.0156 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.016 ug.mL-1 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.03 ug.mL-1 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.0312 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.01152-06
None NON-PROTEIN TARGET MIC 0.0625 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.125 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.01047-08
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.00460-10
None NON-PROTEIN TARGET MIC 12.0 ug.mL-1 10.1128/aac.00788-09
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.00460-10
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.01284-08
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.00046-09
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 48.0 ug.mL-1 10.1128/aac.00788-09
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.00356-10
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.00451-08
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.00451-08
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.01581-08
None NON-PROTEIN TARGET MIC nan None 10.1128/aac.00046-09
None NON-PROTEIN TARGET MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC50 0.125 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC50 0.25 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC50 0.5 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC50 1.0 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.01047-08
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC50 4.0 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC90 0.0625 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC90 0.5 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC90 2.0 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC90 8.0 ug.mL-1 10.1128/aac.01047-08
None NON-PROTEIN TARGET MIC90 8.0 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC90 16.0 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC90 32.0 ug.mL-1 10.1128/aac.01788-09
None NON-PROTEIN TARGET MIC90 64.0 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC90 64.0 ug.mL-1 10.1128/aac.01788-09
None No relevant target Fa 99.16 % 10.1039/C9MD00358D
None No relevant target LogD -1.23 None 10.1021/jm970530e
None No relevant target LogD -1.23 None 10.1124/dmd.111.041665
None No relevant target Peff 0.0 10'-6 cm/s 10.1039/C9MD00358D
None No relevant target Peff 0.38 10'-6 cm/s 10.1039/C9MD00358D
None No relevant target permeability 0.0 ucm/s 10.1016/j.ejmech.2018.01.007
None No relevant target permeability 0.1 ucm/s 10.1016/j.ejmech.2018.01.007
None No relevant target pKa 2.7 None 10.1016/j.ejmech.2009.06.004
None Phospholipidosis Phospholipidosis nan None 10.1080/15376510701857262
None Unchecked Activity 200.0 ug ml-1 10.1074/jbc.m704286200
None Unchecked Activity nan None 10.1128/aac.00029-07
None Unchecked EC50 19.0 ug.mL-1 10.1074/jbc.m704286200
None Unchecked Hepatotoxicity (acute) 7.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 2.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 3.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 0.01 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 0.02 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 0.03 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 0.1 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 0.1 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 0.125 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 0.2 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 0.25 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 0.4 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 0.5 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 0.5 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 1.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 1.0 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 2.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 4.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 6.0 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 8.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 8.0 ug.mL-1 10.1128/aac.00029-07
None Unchecked IC50 16.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 128.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 nan None 10.1128/aac.00019-10
None Unchecked Kcat 0.01 /s 10.1128/aac.00387-08
None Unchecked Kcat 0.042 /s 10.1128/aac.01252-09
None Unchecked Kcat 13.0 /s 10.1128/aac.01062-07
None Unchecked Kcat/Km 7.0 10'5/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 9.6 10'4/M/s 10.1128/aac.01062-07
None Unchecked Kcat/Km 9.9 10'4/M/s 10.1128/aac.01062-07
None Unchecked Kcat/Km nan None 10.1128/aac.00387-08
None Unchecked Km 6000.0 nM 10.1128/aac.01252-09
None Unchecked Km 130000.0 nM 10.1128/aac.01062-07
None Unchecked Km nan None 10.1128/aac.00387-08

Metabolism Information