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1-cyclopropyl-6-fluoro-8-methoxy-7-{octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

AlkaPlorer ID: AK023805

Synonym: None

IUPAC Name: 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid

Structure

SMILES: COC1=C2C(=CC(F)=C1N1C[C@@H]3CCCN[C@@H]3C1)C(=O)C(C(=O)O)=CN2C1CC1

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InChI: InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1

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InChIKey: FABPRXSRWADJSP-MEDUHNTESA-N

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Reference

PubChem CID: 152946

CAS: 151096-09-2

NPASS: NPC480265

Properties Information

Molecule Weight: 401.43800000000016

TPSA？: 83.80000000000001

MolLogP？: 2.3705000000000007

Number of H-Donors: 2

Number of H-Acceptors: 6

RingCount: 5

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter baumannii Acinetobacter baumannii Activity 40.0 % 10.1128/aac.00078-09
Acinetobacter baumannii Acinetobacter baumannii Activity 80.0 % 10.1128/aac.00078-09
Acinetobacter baumannii Acinetobacter baumannii Activity 86.7 % 10.1128/aac.00078-09
Acinetobacter baumannii Acinetobacter baumannii Activity 93.3 % 10.1128/aac.00078-09
Acinetobacter baumannii Acinetobacter baumannii Activity 100.0 % 10.1128/aac.00078-09
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.00418-09
Acinetobacter baumannii Acinetobacter baumannii Inhibition 100.0 % 10.1021/acs.jmedchem.2c01905
Acinetobacter baumannii Acinetobacter baumannii MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Acinetobacter baumannii Acinetobacter baumannii MIC 0.06 ug.mL-1 10.1128/aac.01197-09
Acinetobacter baumannii Acinetobacter baumannii MIC 0.15 ug.mL-1 10.1016/j.bmc.2010.06.098
Acinetobacter baumannii Acinetobacter baumannii MIC 0.15 ug.mL-1 10.1016/j.bmc.2011.03.018
Acinetobacter baumannii Acinetobacter baumannii MIC 0.25 ug.mL-1 10.1016/j.bmcl.2021.128450
Acinetobacter baumannii Acinetobacter baumannii MIC 0.5 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Acinetobacter baumannii Acinetobacter baumannii MIC 2.0 ug.mL-1 10.1016/j.bmcl.2021.128450
Acinetobacter baumannii Acinetobacter baumannii MIC 3.0 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1016/j.bmcl.2021.128450
Acinetobacter baumannii Acinetobacter baumannii MIC 12.0 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.2c01905
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 50.0 ug.mL-1 10.1016/j.bmc.2010.06.098
Acinetobacter baumannii Acinetobacter baumannii MIC 50.0 ug.mL-1 10.1016/j.bmc.2011.03.018
Acinetobacter baumannii Acinetobacter baumannii MIC50 1.0 ug.mL-1 10.1128/aac.01197-09
Acinetobacter baumannii Acinetobacter baumannii MIC50 8.0 ug.mL-1 10.1128/aac.00418-09
Acinetobacter baumannii Acinetobacter baumannii MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Acinetobacter baumannii Acinetobacter baumannii MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Acinetobacter calcoaceticus Acinetobacter calcoaceticus Activity nan None 10.1128/aac.00418-09
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC50 2.0 ug.mL-1 10.1128/aac.00418-09
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Acinetobacter lwoffii Acinetobacter lwoffii Activity nan None 10.1128/aac.00418-09
Acinetobacter lwoffii Acinetobacter lwoffii MIC 0.008 ug.mL-1 10.1128/aac.00418-09
Acinetobacter lwoffii Acinetobacter lwoffii MIC nan None 10.1128/aac.00598-10
Acinetobacter lwoffii Acinetobacter lwoffii MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Acinetobacter lwoffii Acinetobacter lwoffii MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Actinomyces israelii Actinomyces israelii Activity 0.0 % 10.1128/aac.00481-10
Actinomyces israelii Actinomyces israelii Activity 92.0 % 10.1128/aac.00481-10
Actinomyces israelii Actinomyces israelii MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Actinomyces israelii Actinomyces israelii MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Actinomyces israelii Actinomyces israelii MIC90 2.0 ug.mL-1 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii Activity 0.0 % 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii Activity 92.0 % 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Actinomyces naeslundii Actinomyces naeslundii MIC90 2.0 ug.mL-1 10.1128/aac.00481-10
Agaricus bisporus Tyrosinase IC50 1.2 ug.mL-1 10.1016/j.ejmech.2019.111892
Anaerococcus prevotii Anaerococcus prevotii Activity 13.0 % 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii Activity 14.8 % 10.1128/aac.00696-08
Anaerococcus prevotii Anaerococcus prevotii Activity 87.0 % 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii MIC 0.06 ug.mL-1 10.1128/aac.00696-08
Anaerococcus prevotii Anaerococcus prevotii MIC50 0.25 ug.mL-1 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii MIC50 0.5 ug.mL-1 10.1128/aac.00696-08
Anaerococcus prevotii Anaerococcus prevotii MIC90 8.0 ug.mL-1 10.1128/aac.00481-10
Anaerococcus prevotii Anaerococcus prevotii MIC90 16.0 ug.mL-1 10.1128/aac.00696-08
Aspergillus flavus Aspergillus flavus MIC 285500.0 nM 10.1016/j.ejmech.2020.112513
Aspergillus niger Aspergillus niger MIC 100.0 ug.mL-1 10.1016/j.bmc.2011.03.018
Bacillus anthracis Bacillus anthracis Activity 0.0407 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.0657 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.151 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.152 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.161 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.227 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.246 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.276 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.315 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.338 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.339 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.353 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.393 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.46 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.462 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.478 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.516 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.548 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.667 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.707 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.719 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 0.984 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.0 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.01 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.04 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.12 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.17 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.2 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.37 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.38 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.63 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.81 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.82 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.86 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.89 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 1.91 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.08 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.09 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.11 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.16 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.27 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.31 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.4 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.41 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.63 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.73 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.74 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 2.91 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 4.29 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 4.48 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 4.94 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 4.96 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 5.14 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 5.18 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 5.3 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 5.84 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 5.93 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 6.24 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 6.41 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 6.57 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 6.58 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 6.65 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 6.77 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 6.91 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 7.23 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 7.29 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 7.31 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 7.38 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 7.42 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 7.48 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 7.6 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 8.07 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 8.24 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 8.25 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 8.26 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 8.28 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 9.06 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 10.1 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 13.9 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 16.0 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 16.9 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 17.9 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 19.8 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 19.9 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 20.0 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 20.9 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 25.0 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 25.9 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 29.8 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis Activity 30.0 /hr 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 15.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 21.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 22.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 24.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 25.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 32.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 34.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 40.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 41.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 45.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 50.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 71.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 80.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 96.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 99.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 169.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 222.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 629.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 677.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 1740000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 1860000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 1870000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 1880000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 1890000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 1900000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 2360000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 2420000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 19600000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 20600000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 21500000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 21600000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 23500000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 28000000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 36000000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 38500000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 41200000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis CFU/ml 53600000.0 None 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis MBC 1.0 mg/L 10.1128/aac.00802-09
Bacillus anthracis Bacillus anthracis MIC 0.06 ug.mL-1 10.1128/aac.00802-09
Bacillus cereus Bacillus cereus MIC 0.3 ug.mL-1 10.1016/j.bmc.2011.03.018
Bacillus cereus Bacillus cereus MIC 0.6 ug.mL-1 10.1016/j.ejmech.2021.113741
Bacillus spizizenii Bacillus spizizenii MBC 0.032 ug ml-1 10.1016/j.ejmech.2019.06.071
Bacillus spizizenii Bacillus spizizenii MIC 0.025 ug.mL-1 10.1021/acs.jmedchem.8b00644
Bacillus spizizenii Bacillus spizizenii MIC 0.032 ug.mL-1 10.1016/j.ejmech.2019.06.071
Bacillus subtilis Bacillus subtilis MIC 0.015 ug.mL-1 10.1016/j.bmc.2010.06.098
Bacillus subtilis Bacillus subtilis MIC 0.015 ug.mL-1 10.1016/j.bmc.2011.03.018
Bacillus subtilis Bacillus subtilis MIC 0.2 ug.mL-1 10.1021/jm301650g
Bacillus subtilis Bacillus subtilis MIC 4990.0 nM 10.1016/j.ejmech.2019.01.038
Bacillus subtilis Bacillus subtilis MIC nan None 10.1016/j.ejmech.2017.10.045
Bacteria Cell membrane Activity nan None 10.1021/acs.jmedchem.0c00826
Bacteroides caccae Bacteroides caccae Activity 9.0 % 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae Activity 18.0 % 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae Activity 22.2 % 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae Activity 36.4 % 10.1128/aac.01435-06
Bacteroides caccae Bacteroides caccae Activity 50.0 % 10.1128/aac.00696-08
Bacteroides caccae Bacteroides caccae Activity 72.0 % 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae Activity 91.0 % 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae MIC 0.25 ug.mL-1 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae MIC 0.25 ug.mL-1 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC 0.5 ug.mL-1 10.1128/aac.00696-08
Bacteroides caccae Bacteroides caccae MIC 3.85 ug.mL-1 10.1128/aac.01435-06
Bacteroides caccae Bacteroides caccae MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae MIC50 4.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides caccae Bacteroides caccae MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides caccae Bacteroides caccae MIC90 16.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides caccae Bacteroides caccae MIC90 32.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides caccae Bacteroides caccae MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides fragilis Bacteroides fragilis Activity 7.0 % 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis Activity 9.7 % 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis Activity 11.0 % 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis Activity 27.3 % 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis Activity 27.3 % 10.1128/aac.01435-06
Bacteroides fragilis Bacteroides fragilis Activity 29.3 % 10.1128/aac.00696-08
Bacteroides fragilis Bacteroides fragilis Activity 84.0 % 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis Activity 90.0 % 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis Activity 95.0 % 10.1128/aac.00418-09
Bacteroides fragilis Bacteroides fragilis MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis MIC 0.25 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Bacteroides fragilis Bacteroides fragilis MIC 0.25 ug.mL-1 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis MIC 0.25 ug.mL-1 10.1128/aac.00696-08
Bacteroides fragilis Bacteroides fragilis MIC 1.83 ug.mL-1 10.1128/aac.01435-06
Bacteroides fragilis Bacteroides fragilis MIC50 0.5 ug.mL-1 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis MIC50 0.5 ug.mL-1 10.1128/aac.00418-09
Bacteroides fragilis Bacteroides fragilis MIC50 0.5 ug.mL-1 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides fragilis Bacteroides fragilis MIC90 1.0 ug.mL-1 10.1039/C9MD00120D
Bacteroides fragilis Bacteroides fragilis MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis MIC90 2.0 ug.mL-1 10.1128/aac.00418-09
Bacteroides fragilis Bacteroides fragilis MIC90 4.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides fragilis Bacteroides fragilis MIC90 8.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides fragilis Bacteroides fragilis MIC90 8.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides fragilis Bacteroides fragilis MIC90 8.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides ovatus Bacteroides ovatus Activity 18.0 % 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus Activity 24.4 % 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus Activity 38.3 % 10.1128/aac.01435-06
Bacteroides ovatus Bacteroides ovatus Activity 40.0 % 10.1128/aac.00696-08
Bacteroides ovatus Bacteroides ovatus Activity 72.0 % 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus MIC 0.125 ug.mL-1 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides ovatus Bacteroides ovatus MIC 5.49 ug.mL-1 10.1128/aac.01435-06
Bacteroides ovatus Bacteroides ovatus MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus MIC50 2.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides ovatus Bacteroides ovatus MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides ovatus Bacteroides ovatus MIC90 32.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides ovatus Bacteroides ovatus MIC90 32.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides ovatus Bacteroides ovatus MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides sp. Bacteroides sp. Activity 28.3 % 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. FC 4.0 None 10.1128/aac.00306-08
Bacteroides sp. Bacteroides sp. FC 6.0 None 10.1128/aac.00306-08
Bacteroides sp. Bacteroides sp. MIC 0.25 ug.mL-1 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides sp. Bacteroides sp. MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris Activity 28.3 % 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris Activity 36.4 % 10.1128/aac.01435-06
Bacteroides stercoris Bacteroides stercoris MIC 0.25 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC 3.85 ug.mL-1 10.1128/aac.01435-06
Bacteroides stercoris Bacteroides stercoris MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides stercoris Bacteroides stercoris MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 7.0 % 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 17.0 % 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 18.0 % 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 26.3 % 10.1128/aac.01435-06
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 30.8 % 10.1128/aac.00696-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 72.0 % 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 87.0 % 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 0.5 ug.mL-1 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 0.5 ug.mL-1 10.1128/aac.00696-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 3.71 ug.mL-1 10.1128/aac.01435-06
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 1.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 4.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 32.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides uniformis Bacteroides uniformis Activity 9.0 % 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis Activity 14.3 % 10.1128/aac.00696-08
Bacteroides uniformis Bacteroides uniformis Activity 24.5 % 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis Activity 38.6 % 10.1128/aac.01435-06
Bacteroides uniformis Bacteroides uniformis Activity 91.0 % 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis MIC 0.25 ug.mL-1 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC 1.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides uniformis Bacteroides uniformis MIC 5.57 ug.mL-1 10.1128/aac.01435-06
Bacteroides uniformis Bacteroides uniformis MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis MIC50 4.0 ug.mL-1 10.1128/aac.00696-08
Bacteroides uniformis Bacteroides uniformis MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC90 32.0 ug.mL-1 10.1128/aac.00081-08
Bacteroides uniformis Bacteroides uniformis MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
Bacteroides uniformis Bacteroides uniformis MIC90 64.0 ug.mL-1 10.1128/aac.00696-08
Bos taurus Bone Activity 0.01 % 10.1021/jm801007z
Candida albicans Candida albicans MFC 0.5 ug ml-1 10.1016/j.bmcl.2015.04.081
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.bmcl.2015.04.081
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.bmcl.2015.10.028
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.ejmech.2013.12.054
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.ejmech.2019.03.059
Candida albicans Candida albicans MIC 2.0 ug.mL-1 10.1016/j.bmcl.2018.03.037
Candida albicans Candida albicans MIC 1100.0 nM 10.1016/j.ejmech.2020.112513
Candida albicans Candida albicans MIC nan None 10.1016/j.bmcl.2019.02.033
Candida tropicalis Candida tropicalis MIC 100.0 ug.mL-1 10.1016/j.bmc.2011.03.018
Canis lupus familiaris MDCK CC50 161000.0 nM 10.1016/j.ejmech.2011.03.026
Chlamydia pneumoniae Chlamydia pneumoniae MIC 0.125 ug.mL-1 10.1021/jm301650g
Chlorocebus sabaeus Vero CC50 128.0 ug.mL-1 10.1016/j.ejmech.2017.11.090
Chlorocebus sabaeus Vero CC50 128.0 ug.mL-1 10.1016/j.ejmech.2019.07.057
Chlorocebus sabaeus Vero CC50 160.8 None 10.1016/j.ejmech.2010.04.027
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.bmcl.2012.05.096
Citrobacter freundii Citrobacter freundii Activity 85.0 % 10.1128/aac.00418-09
Citrobacter freundii Citrobacter freundii MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Citrobacter freundii Citrobacter freundii MIC 0.06 ug.mL-1 10.1128/aac.01374-09
Citrobacter freundii Citrobacter freundii MIC 0.12 ug.mL-1 10.1128/aac.01197-09
Citrobacter freundii Citrobacter freundii MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Citrobacter freundii Citrobacter freundii MIC50 0.5 ug.mL-1 10.1128/aac.01197-09
Citrobacter freundii Citrobacter freundii MIC50 2.0 ug.mL-1 10.1128/aac.01374-09
Citrobacter freundii Citrobacter freundii MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Citrobacter freundii Citrobacter freundii MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Citrobacter freundii Citrobacter freundii MIC90 8.0 ug.mL-1 10.1128/aac.01374-09
Citrobacter koseri Citrobacter koseri Activity nan None 10.1128/aac.00418-09
Citrobacter koseri Citrobacter koseri MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Citrobacter koseri Citrobacter koseri MIC50 0.03 ug.mL-1 10.1128/aac.00418-09
Citrobacter koseri Citrobacter koseri MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Clostridioides difficile Clostridioides difficile Activity 20.0 % 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile Activity 25.0 % 10.1128/aac.00481-10
Clostridioides difficile Clostridioides difficile Activity 46.2 % 10.1128/aac.00476-08
Clostridioides difficile Clostridioides difficile Activity 75.0 % 10.1128/aac.00481-10
Clostridioides difficile Clostridioides difficile Activity 130.0 % 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile Activity nan None 10.1128/aac.00306-08
Clostridioides difficile Clostridioides difficile Activity nan None 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile Activity nan None 10.1128/aac.00696-08
Clostridioides difficile Clostridioides difficile Activity nan None 10.1128/aac.01582-06
Clostridioides difficile Clostridioides difficile FC 0.8 None 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile FC 2.1 None 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile FC 2.9 None 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile FC 3.1 None 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile FC 4.0 None 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile FC 14.0 None 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile FC 16.5 None 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile FC 17.3 None 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile MIC 0.5 ug.mL-1 10.1128/aac.00476-08
Clostridioides difficile Clostridioides difficile MIC 1.0 ug.mL-1 10.1128/aac.00481-10
Clostridioides difficile Clostridioides difficile MIC 1.0 ug.mL-1 10.1128/aac.01252-08
Clostridioides difficile Clostridioides difficile MIC 2.0 ug.mL-1 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile MIC 2.0 ug.mL-1 10.1128/aac.00696-08
Clostridioides difficile Clostridioides difficile MIC 2.0 ug.mL-1 10.1128/aac.01252-08
Clostridioides difficile Clostridioides difficile MIC 2.0 ug.mL-1 10.1128/aac.01582-06
Clostridioides difficile Clostridioides difficile MIC 4.0 ug.mL-1 10.1128/aac.01252-08
Clostridioides difficile Clostridioides difficile MIC 8.0 ug.mL-1 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile MIC 8.0 ug.mL-1 10.1128/aac.01252-08
Clostridioides difficile Clostridioides difficile MIC 16.0 ug.mL-1 10.1128/aac.01252-08
Clostridioides difficile Clostridioides difficile MIC 32.0 ug.mL-1 10.1128/aac.00306-08
Clostridioides difficile Clostridioides difficile MIC 32.0 ug.mL-1 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile MIC 32.0 ug.mL-1 10.1128/aac.01252-08
Clostridioides difficile Clostridioides difficile MIC 32.0 ug.mL-1 10.1128/aac.01582-06
Clostridioides difficile Clostridioides difficile MIC 45.0 ug.mL-1 10.1128/aac.00306-08
Clostridioides difficile Clostridioides difficile MIC 64.0 ug.mL-1 10.1128/aac.00532-09
Clostridioides difficile Clostridioides difficile MIC 64.0 ug.mL-1 10.1128/aac.01252-08
Clostridioides difficile Clostridioides difficile MIC 64.0 ug.mL-1 10.1128/aac.01582-06
Clostridioides difficile Clostridioides difficile MIC 80.0 ug.mL-1 10.1128/aac.00306-08
Clostridioides difficile Clostridioides difficile MIC 128.0 ug.mL-1 10.1128/aac.01252-08
Clostridioides difficile Clostridioides difficile MIC 256.0 ug.mL-1 10.1128/aac.01252-08
Clostridioides difficile Clostridioides difficile MIC 256.0 ug.mL-1 10.1128/aac.01582-06
Clostridioides difficile Clostridioides difficile MIC50 1.0 ug.mL-1 10.1128/aac.01623-06
Clostridioides difficile Clostridioides difficile MIC50 16.0 ug.mL-1 10.1128/aac.00476-08
Clostridioides difficile Clostridioides difficile MIC50 16.0 ug.mL-1 10.1128/aac.00481-10
Clostridioides difficile Clostridioides difficile MIC90 16.0 ug.mL-1 10.1128/aac.01623-06
Clostridioides difficile Clostridioides difficile MIC90 32.0 ug.mL-1 10.1128/aac.00481-10
Clostridioides difficile Clostridioides difficile MIC90 256.0 ug.mL-1 10.1128/aac.00476-08
[Clostridium] innocuum [Clostridium] innocuum Activity 0.0 % 10.1128/aac.00696-08
[Clostridium] innocuum [Clostridium] innocuum MIC 0.5 ug.mL-1 10.1128/aac.00696-08
[Clostridium] innocuum [Clostridium] innocuum MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
[Clostridium] innocuum [Clostridium] innocuum MIC90 2.0 ug.mL-1 10.1128/aac.00696-08
Clostridium paraputrificum Clostridium paraputrificum Activity 0.0 % 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum Activity 0.0 % 10.1128/aac.00696-08
Clostridium paraputrificum Clostridium paraputrificum Activity 93.0 % 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum MIC 0.5 ug.mL-1 10.1128/aac.00696-08
Clostridium paraputrificum Clostridium paraputrificum MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Clostridium paraputrificum Clostridium paraputrificum MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum MIC90 2.0 ug.mL-1 10.1128/aac.00696-08
Clostridium perfringens Clostridium perfringens Activity 0.0 % 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens Activity 0.0 % 10.1128/aac.00696-08
Clostridium perfringens Clostridium perfringens Activity 7.0 % 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens Activity 93.0 % 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens Activity 93.0 % 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens Activity 100.0 % 10.1128/aac.00418-09
Clostridium perfringens Clostridium perfringens MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Clostridium perfringens Clostridium perfringens MIC 0.25 ug.mL-1 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens MIC 0.5 ug.mL-1 10.1128/aac.00696-08
Clostridium perfringens Clostridium perfringens MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens MIC50 0.5 ug.mL-1 10.1128/aac.00418-09
Clostridium perfringens Clostridium perfringens MIC50 0.5 ug.mL-1 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens MIC50 0.5 ug.mL-1 10.1128/aac.00696-08
Clostridium perfringens Clostridium perfringens MIC90 0.25 ug.mL-1 10.1039/C9MD00120D
Clostridium perfringens Clostridium perfringens MIC90 0.5 ug.mL-1 10.1128/aac.00418-09
Clostridium perfringens Clostridium perfringens MIC90 0.5 ug.mL-1 10.1128/aac.00481-10
Clostridium perfringens Clostridium perfringens MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens MIC90 1.0 ug.mL-1 10.1128/aac.00696-08
Clostridium septicum Clostridium septicum Activity 0.0 % 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum Activity 93.0 % 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium Activity 0.0 % 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium Activity 0.0 % 10.1128/aac.00696-08
Clostridium tertium Clostridium tertium Activity 93.0 % 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC 0.5 ug.mL-1 10.1128/aac.00696-08
Clostridium tertium Clostridium tertium MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
Clostridium tertium Clostridium tertium MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC90 2.0 ug.mL-1 10.1128/aac.00696-08
Corynebacterium sp. Corynebacterium sp. Activity nan None 10.1128/aac.00845-09
Corynebacterium sp. Corynebacterium sp. MIC 0.25 ug.mL-1 10.1128/aac.00845-09
Corynebacterium sp. Corynebacterium sp. MIC50 1.0 ug.mL-1 10.1128/aac.00845-09
Corynebacterium sp. Corynebacterium sp. MIC90 8.0 ug.mL-1 10.1128/aac.00845-09
Cricetulus griseus CHO CC50 nan None 10.1021/jm2002124
Cutibacterium acnes Cutibacterium acnes Activity 0.0 % 10.1128/aac.00696-08
Cutibacterium acnes Cutibacterium acnes Activity 100.0 % 10.1128/aac.00418-09
Cutibacterium acnes Cutibacterium acnes MIC 0.125 ug.mL-1 10.1128/aac.00696-08
Cutibacterium acnes Cutibacterium acnes MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Cutibacterium acnes Cutibacterium acnes MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Cutibacterium acnes Cutibacterium acnes MIC50 0.25 ug.mL-1 10.1128/aac.00696-08
Cutibacterium acnes Cutibacterium acnes MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Cutibacterium acnes Cutibacterium acnes MIC90 0.5 ug.mL-1 10.1128/aac.00696-08
Dialister invisus Dialister invisus Activity 1.0 ug ml-1 10.1128/aac.00538-07
Dialister invisus Dialister invisus Activity 2.0 ug ml-1 10.1128/aac.00538-07
Dialister invisus Dialister invisus MIC 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus Activity 1.0 ug ml-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus Activity 2.0 ug ml-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC50 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC90 0.25 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes Activity 1.0 ug ml-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes Activity 2.0 ug ml-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC50 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC90 0.06 ug.mL-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens Activity 1.0 ug ml-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens Activity 2.0 ug ml-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens MIC 0.06 ug.mL-1 10.1128/aac.00538-07
Eggerthella lenta Eggerthella lenta Activity 0.0 % 10.1128/aac.00481-10
Eggerthella lenta Eggerthella lenta Activity 92.0 % 10.1128/aac.00481-10
Eggerthella lenta Eggerthella lenta MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Eggerthella lenta Eggerthella lenta MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Eggerthella lenta Eggerthella lenta MIC90 2.0 ug.mL-1 10.1128/aac.00481-10
Enterobacter cloacae Enterobacter cloacae Activity 68.1 % 10.1128/aac.00078-09
Enterobacter cloacae Enterobacter cloacae Activity 87.5 % 10.1128/aac.00078-09
Enterobacter cloacae Enterobacter cloacae Activity 90.3 % 10.1128/aac.00078-09
Enterobacter cloacae Enterobacter cloacae Activity 91.7 % 10.1128/aac.00078-09
Enterobacter cloacae Enterobacter cloacae Activity 93.1 % 10.1128/aac.00078-09
Enterobacter cloacae Enterobacter cloacae Activity 94.0 % 10.1128/aac.00418-09
Enterobacter cloacae Enterobacter cloacae Activity 94.4 % 10.1128/aac.00078-09
Enterobacter cloacae Enterobacter cloacae Activity 98.6 % 10.1128/aac.00078-09
Enterobacter cloacae Enterobacter cloacae Activity 100.0 % 10.1128/aac.00078-09
Enterobacter cloacae Enterobacter cloacae MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Enterobacter cloacae Enterobacter cloacae MIC 0.06 ug.mL-1 10.1128/aac.01374-09
Enterobacter cloacae Enterobacter cloacae MIC 0.06 ug.mL-1 10.1128/aac.01534-08
Enterobacter cloacae Enterobacter cloacae MIC 0.25 ug.mL-1 10.1128/aac.01197-09
Enterobacter cloacae Enterobacter cloacae MIC 2.0 ug.mL-1 10.1128/aac.01534-08
Enterobacter cloacae Enterobacter cloacae MIC 4.0 ug.mL-1 10.1128/aac.01534-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.01616-06
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1128/aac.00726-07
Enterobacter cloacae Enterobacter cloacae MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Enterobacter cloacae Enterobacter cloacae MIC50 0.06 ug.mL-1 10.1128/aac.01374-09
Enterobacter cloacae Enterobacter cloacae MIC50 2.0 ug.mL-1 10.1128/aac.01197-09
Enterobacter cloacae Enterobacter cloacae MIC90 0.12 ug.mL-1 10.1128/aac.01374-09
Enterobacter cloacae Enterobacter cloacae MIC90 2.0 ug.mL-1 10.1128/aac.00418-09
Enterobacter cloacae Enterobacter cloacae MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Enterobacteriaceae Enterobacteriaceae MIC90 0.12 ug.mL-1 10.1128/aac.00078-09
Enterococcus Enterococcus FC 6.0 None 10.1128/aac.00306-08
Enterococcus Enterococcus MIC 0.25 ug.mL-1 10.1128/aac.00723-10
Enterococcus Enterococcus MIC 8.0 ug.mL-1 10.1128/aac.00959-06
Enterococcus Enterococcus MIC 64000.0 ug.mL-1 10.1128/aac.00959-06
Enterococcus Enterococcus MIC50 2.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus Enterococcus MIC90 2.0 ug.mL-1 10.1039/C9MD00120D
Enterococcus Enterococcus MIC90 4.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecalis Enterococcus faecalis Activity 1.2 % 10.1128/aac.00078-09
Enterococcus faecalis Enterococcus faecalis Activity 4.9 % 10.1128/aac.00078-09
Enterococcus faecalis Enterococcus faecalis Activity 44.4 % 10.1128/aac.00078-09
Enterococcus faecalis Enterococcus faecalis Activity 65.4 % 10.1128/aac.00078-09
Enterococcus faecalis Enterococcus faecalis Activity 67.9 % 10.1128/aac.00078-09
Enterococcus faecalis Enterococcus faecalis Activity 72.8 % 10.1128/aac.00078-09
Enterococcus faecalis Enterococcus faecalis Activity 100.0 % 10.1128/aac.00078-09
Enterococcus faecalis Enterococcus faecalis Activity nan None 10.1128/aac.00418-09
Enterococcus faecalis Enterococcus faecalis Log 1/C 6.55 None 10.1021/jm030986y
Enterococcus faecalis Enterococcus faecalis MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecalis Enterococcus faecalis MIC 0.06 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecalis Enterococcus faecalis MIC 0.125 ug.mL-1 10.1016/j.bmcl.2005.11.064
Enterococcus faecalis Enterococcus faecalis MIC 0.2 ug.mL-1 10.1016/j.bmc.2009.08.026
Enterococcus faecalis Enterococcus faecalis MIC 0.2 ug.mL-1 10.1016/j.bmcl.2004.07.064
Enterococcus faecalis Enterococcus faecalis MIC 0.2 ug.mL-1 10.1021/acs.jmedchem.8b00644
Enterococcus faecalis Enterococcus faecalis MIC 0.2 ug.mL-1 10.1021/jm020328y
Enterococcus faecalis Enterococcus faecalis MIC 0.2 ug.mL-1 10.1021/jm301650g
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1021/jm050035f
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1128/aac.01197-09
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1128/aac.01374-09
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2015.10.027
Enterococcus faecalis Enterococcus faecalis MIC 0.6 ug.mL-1 10.1016/j.ejmech.2021.113741
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/j.ejmech.2011.03.026
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2011.03.026
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Enterococcus faecalis Enterococcus faecalis MIC 16.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Enterococcus faecalis Enterococcus faecalis MIC 16.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Enterococcus faecalis Enterococcus faecalis MIC 900.0 nM 10.1021/acs.jnatprod.6b00809
Enterococcus faecalis Enterococcus faecalis MIC 2490.0 nM 10.1016/j.ejmech.2019.01.038
Enterococcus faecalis Enterococcus faecalis MIC nan None 10.1016/j.ejmech.2017.10.045
Enterococcus faecalis Enterococcus faecalis MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecalis Enterococcus faecalis MIC50 0.25 ug.mL-1 10.1128/aac.01374-09
Enterococcus faecalis Enterococcus faecalis MIC50 0.5 ug.mL-1 10.1128/aac.01197-09
Enterococcus faecalis Enterococcus faecalis MIC50 1.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecalis Enterococcus faecalis MIC50 16.0 ug.mL-1 10.1016/j.bmc.2009.08.026
Enterococcus faecalis Enterococcus faecalis MIC90 1.95 ug.mL-1 10.1016/j.bmcl.2017.01.073
Enterococcus faecalis Enterococcus faecalis MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Enterococcus faecalis Enterococcus faecalis MIC90 16.0 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecalis Enterococcus faecalis MIC90 16.0 ug.mL-1 10.1128/aac.01374-09
Enterococcus faecalis Enterococcus faecalis MIC90 32.0 ug.mL-1 10.1016/j.bmc.2009.08.026
Enterococcus faecalis Enterococcus faecalis MIC90 32.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecium Enterococcus faecium Activity 13.2 % 10.1128/aac.00078-09
Enterococcus faecium Enterococcus faecium Activity 18.4 % 10.1128/aac.00078-09
Enterococcus faecium Enterococcus faecium Activity 26.3 % 10.1128/aac.00078-09
Enterococcus faecium Enterococcus faecium Activity 28.9 % 10.1128/aac.00078-09
Enterococcus faecium Enterococcus faecium Activity 34.2 % 10.1128/aac.00078-09
Enterococcus faecium Enterococcus faecium Activity 100.0 % 10.1128/aac.00078-09
Enterococcus faecium Enterococcus faecium Activity nan None 10.1128/aac.00418-09
Enterococcus faecium Enterococcus faecium MIC 0.008 ug.mL-1 10.1016/j.ejmech.2011.10.048
Enterococcus faecium Enterococcus faecium MIC 0.12 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecium Enterococcus faecium MIC 0.125 ug.mL-1 10.1016/j.bmcl.2005.11.064
Enterococcus faecium Enterococcus faecium MIC 0.125 ug.mL-1 10.1016/j.ejmech.2011.10.048
Enterococcus faecium Enterococcus faecium MIC 0.25 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecium Enterococcus faecium MIC 0.5 ug.mL-1 10.1016/j.bmcl.2016.03.050
Enterococcus faecium Enterococcus faecium MIC 1.0 ug.mL-1 10.1128/aac.01197-09
Enterococcus faecium Enterococcus faecium MIC 1.0 ug.mL-1 10.1128/aac.01374-09
Enterococcus faecium Enterococcus faecium MIC 2.0 ug.mL-1 10.1016/j.ejmech.2011.03.026
Enterococcus faecium Enterococcus faecium MIC 2.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Enterococcus faecium Enterococcus faecium MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Enterococcus faecium Enterococcus faecium MIC 8.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Enterococcus faecium Enterococcus faecium MIC 16.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Enterococcus faecium Enterococcus faecium MIC 16.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Enterococcus faecium Enterococcus faecium MIC 1900.0 nM 10.1021/acs.jnatprod.6b00809
Enterococcus faecium Enterococcus faecium MIC 7800.0 nM 10.1021/acs.jnatprod.6b00809
Enterococcus faecium Enterococcus faecium MIC50 4.0 ug.mL-1 10.1016/j.bmc.2009.08.026
Enterococcus faecium Enterococcus faecium MIC50 4.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecium Enterococcus faecium MIC50 4.0 ug.mL-1 10.1128/aac.01374-09
Enterococcus faecium Enterococcus faecium MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Enterococcus faecium Enterococcus faecium MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Enterococcus faecium Enterococcus faecium MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Enterococcus faecium Enterococcus faecium MIC90 16.0 ug.mL-1 10.1128/aac.01374-09
Enterococcus faecium Enterococcus faecium MIC90 32.0 ug.mL-1 10.1016/j.bmc.2009.08.026
Enterococcus faecium Enterococcus faecium MIC90 32.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecium Enterococcus faecium MIC90 64.0 ug.mL-1 10.1128/aac.00418-09
Enterococcus hirae Enterococcus hirae MBC 32.0 ug ml-1 10.1016/j.ejmech.2019.06.071
Enterococcus hirae Enterococcus hirae MIC 16.0 ug.mL-1 10.1016/j.ejmech.2019.06.071
Enterococcus sp. Enterococcus sp. Activity nan None 10.1128/aac.01538-07
Enterococcus sp. Enterococcus sp. MIC50 2.0 ug.mL-1 10.1021/jm020328y
Enterococcus sp. Enterococcus sp. MIC50 16.0 ug.mL-1 10.1021/jm020328y
Enterococcus sp. Enterococcus sp. MIC90 8.0 ug.mL-1 10.1021/jm020328y
Enterococcus sp. Enterococcus sp. MIC90 32.0 ug.mL-1 10.1021/jm020328y
Escherichia coli DNA gyrase CC25 0.5 uM 10.1128/aac.01380-07
Escherichia coli DNA gyrase IC50 300.0 nM 10.1016/j.bmcl.2005.11.065
Escherichia coli DNA gyrase IC50 2500.0 nM 10.1128/aac.01380-07
Escherichia coli DNA repair protein RecN FC 14.0 None 10.1021/acs.jmedchem.0c00328
Escherichia coli Escherichia coli Activity 2.0 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli Activity 4.0 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli Activity 8.0 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli Activity 16.0 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli Activity 32.0 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli Activity 60.3 % 10.1128/aac.00078-09
Escherichia coli Escherichia coli Activity 67.1 % 10.1128/aac.00078-09
Escherichia coli Escherichia coli Activity 68.8 % 10.1128/aac.00078-09
Escherichia coli Escherichia coli Activity 73.5 % 10.1128/aac.00078-09
Escherichia coli Escherichia coli Activity 75.1 % 10.1128/aac.00078-09
Escherichia coli Escherichia coli Activity 75.5 % 10.1128/aac.00078-09
Escherichia coli Escherichia coli Activity 77.3 % 10.1128/aac.00078-09
Escherichia coli Escherichia coli Activity 80.3 % 10.1128/aac.00078-09
Escherichia coli Escherichia coli Activity 100.0 % 10.1128/aac.00078-09
Escherichia coli Escherichia coli LD99 0.5 ug ml-1 10.1128/aac.01054-10
Escherichia coli Escherichia coli Log 1/C 7.46 None 10.1021/jm030986y
Escherichia coli Escherichia coli MBC 0.008 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MBC 0.015 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MBC 0.125 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MBC 0.25 ug ml-1 10.1016/j.ejmech.2019.06.071
Escherichia coli Escherichia coli MBC 0.25 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MBC 0.5 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MBC 1.0 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MBC 2.0 ug ml-1 10.1016/j.bmcl.2015.04.081
Escherichia coli Escherichia coli MBC 2.0 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MBC 4.0 ug ml-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MIC 0.002 ug.mL-1 10.1128/aac.00026-08
Escherichia coli Escherichia coli MIC 0.002 ug.mL-1 10.1128/aac.00143-07
Escherichia coli Escherichia coli MIC 0.002 ug.mL-1 10.1128/aac.00274-07
Escherichia coli Escherichia coli MIC 0.002 ug.mL-1 10.1128/aac.00339-07
Escherichia coli Escherichia coli MIC 0.002 ug.mL-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MIC 0.003 ug.mL-1 10.1021/jm020328y
Escherichia coli Escherichia coli MIC 0.003 ug.mL-1 10.1128/aac.00026-08
Escherichia coli Escherichia coli MIC 0.004 ug.mL-1 10.1016/j.bmcl.2011.05.112
Escherichia coli Escherichia coli MIC 0.004 ug.mL-1 10.1128/aac.00026-08
Escherichia coli Escherichia coli MIC 0.004 ug.mL-1 10.1128/aac.00143-07
Escherichia coli Escherichia coli MIC 0.004 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 0.004 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 0.006 ug.mL-1 10.1016/j.bmc.2009.08.026
Escherichia coli Escherichia coli MIC 0.006 ug.mL-1 10.1016/j.bmcl.2004.07.064
Escherichia coli Escherichia coli MIC 0.006 ug.mL-1 10.1016/j.ejmech.2018.08.095
Escherichia coli Escherichia coli MIC 0.006 ug.mL-1 10.1128/aac.00143-07
Escherichia coli Escherichia coli MIC 0.0078 ug.mL-1 10.1128/aac.00330-08
Escherichia coli Escherichia coli MIC 0.008 ug.mL-1 10.1016/j.ejmech.2011.10.048
Escherichia coli Escherichia coli MIC 0.008 ug.mL-1 10.1016/j.ejmech.2014.09.029
Escherichia coli Escherichia coli MIC 0.008 ug.mL-1 10.1128/aac.00026-08
Escherichia coli Escherichia coli MIC 0.008 ug.mL-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MIC 0.01 ug.mL-1 10.1128/aac.00070-07
Escherichia coli Escherichia coli MIC 0.01 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 0.01 ug.mL-1 10.1128/aac.01616-06
Escherichia coli Escherichia coli MIC 0.012 ug.mL-1 10.1021/acs.jmedchem.8b00644
Escherichia coli Escherichia coli MIC 0.012 ug.mL-1 10.1021/jm301650g
Escherichia coli Escherichia coli MIC 0.012 ug.mL-1 10.1128/aac.00026-08
Escherichia coli Escherichia coli MIC 0.013 ug.mL-1 10.1016/j.bmcl.2005.11.064
Escherichia coli Escherichia coli MIC 0.015 ug.mL-1 10.1016/j.bmcl.2005.11.065
Escherichia coli Escherichia coli MIC 0.015 ug.mL-1 10.1016/j.bmcl.2012.05.063
Escherichia coli Escherichia coli MIC 0.015 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC 0.015 ug.mL-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MIC 0.016 ug.mL-1 10.1128/aac.00339-07
Escherichia coli Escherichia coli MIC 0.024 ug.mL-1 10.1021/acs.jmedchem.8b00114
Escherichia coli Escherichia coli MIC 0.028 ug.mL-1 10.1128/aac.00647-07
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1016/j.bmc.2010.06.098
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1016/j.bmc.2011.03.018
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1021/jm101604v
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01374-09
Escherichia coli Escherichia coli MIC 0.031 ug.mL-1 10.1016/j.bmcl.2015.07.044
Escherichia coli Escherichia coli MIC 0.031 ug.mL-1 10.1016/j.bmcl.2021.128484
Escherichia coli Escherichia coli MIC 0.032 ug.mL-1 10.1128/aac.00143-07
Escherichia coli Escherichia coli MIC 0.032 ug.mL-1 10.1128/aac.00274-07
Escherichia coli Escherichia coli MIC 0.047 ug.mL-1 10.1128/aac.00026-08
Escherichia coli Escherichia coli MIC 0.047 ug.mL-1 10.1128/aac.00294-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1016/j.bmcl.2015.10.027
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1016/j.bmcl.2016.03.050
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1016/j.bmcl.2017.10.006
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1016/j.bmcl.2021.128450
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1021/jm050035f
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00921-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01534-08
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00143-07
Escherichia coli Escherichia coli MIC 0.08 ug.mL-1 10.1021/jm1003304
Escherichia coli Escherichia coli MIC 0.094 ug.mL-1 10.1128/aac.00143-07
Escherichia coli Escherichia coli MIC 0.1 ug.mL-1 10.1021/acs.jmedchem.8b00644
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00070-07
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01616-06
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1016/j.ejmech.2019.06.071
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01054-10
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MIC 0.156 ug.mL-1 10.1016/j.bmcl.2011.05.112
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00070-07
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01616-06
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.bmcl.2021.128450
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.ejmech.2011.10.048
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.ejmech.2014.09.029
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b00867
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.bmcl.2018.03.037
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00726-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.04.081
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.10.028
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2016.11.001
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2019.02.033
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.ejmech.2011.03.026
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.ejmech.2013.12.054
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.ejmech.2019.03.059
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00921-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00927-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1021/acs.jmedchem.8b00644
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.bmcl.2015.07.044
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.bmcl.2021.128450
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01374-09
Escherichia coli Escherichia coli MIC 10.0 ug.mL-1 10.1128/aac.00330-08
Escherichia coli Escherichia coli MIC 11.54 ug.mL-1 10.1016/j.ejmech.2018.08.095
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01534-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00339-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 50.0 ug.mL-1 10.1016/j.bmc.2010.06.098
Escherichia coli Escherichia coli MIC 50.0 ug.mL-1 10.1016/j.bmc.2011.03.018
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmcl.2013.05.082
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1016/j.bmcl.2015.04.081
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1016/j.bmcl.2015.10.028
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1016/j.bmcl.2016.11.001
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1016/j.ejmech.2013.12.054
Escherichia coli Escherichia coli MIC 140.0 nM 10.1021/acs.jmedchem.2c00266
Escherichia coli Escherichia coli MIC 310.0 nM 10.1016/j.ejmech.2019.01.038
Escherichia coli Escherichia coli MIC 500.0 nM 10.1016/j.ejmech.2020.112513
Escherichia coli Escherichia coli MIC 1250.0 nM 10.1016/j.ejmech.2019.01.038
Escherichia coli Escherichia coli MIC 3400.0 nM 10.1016/j.ejmech.2020.112513
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.00921-08
Escherichia coli Escherichia coli MIC50 0.06 ug.mL-1 10.1016/j.bmcl.2017.10.006
Escherichia coli Escherichia coli MIC50 0.06 ug.mL-1 10.1128/aac.01374-09
Escherichia coli Escherichia coli MIC50 0.5 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC50 32.0 ug.mL-1 10.1128/aac.01374-09
Escherichia coli Escherichia coli MIC90 0.06 ug.mL-1 10.1039/C9MD00120D
Escherichia coli Escherichia coli MIC90 0.5 ug.mL-1 10.1128/aac.01374-09
Escherichia coli Escherichia coli MIC90 1.0 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC90 1.95 ug.mL-1 10.1016/j.bmcl.2017.01.073
Escherichia coli Escherichia coli MIC90 4.0 ug.mL-1 10.1016/j.ejmech.2018.08.095
Escherichia coli Escherichia coli MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1016/j.bmcl.2017.10.006
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1016/j.ejmech.2018.08.095
Escherichia coli Escherichia coli MIC90 128.0 ug.mL-1 10.1128/aac.01374-09
Escherichia coli Escherichia coli MPC 0.06 ug ml-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MPC 0.125 ug ml-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MPC 0.25 ug ml-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MPC 2.0 ug ml-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli MPC 4.0 ug ml-1 10.1128/aac.01444-06
Escherichia coli Escherichia coli PD50 3.0 mg kg-1 10.1016/j.bmcl.2017.10.006
Escherichia coli Escherichia coli Ratio 1.0 None 10.1128/aac.00330-08
Escherichia coli Escherichia coli Ratio 1.0 None 10.1128/aac.00647-07
Escherichia coli Escherichia coli Ratio 2.0 None 10.1128/aac.00330-08
Escherichia coli Escherichia coli Ratio 4.0 None 10.1128/aac.00921-08
Escherichia coli Escherichia coli Ratio 4.0 None 10.1128/aac.01054-10
Escherichia coli Escherichia coli Ratio 5.0 None 10.1128/aac.00647-07
Escherichia coli Escherichia coli Ratio 8.0 None 10.1128/aac.00339-07
Escherichia coli Escherichia coli Ratio 8.0 None 10.1128/aac.00927-10
Escherichia coli Escherichia coli Ratio 9.0 None 10.1128/aac.00647-07
Escherichia coli Escherichia coli Ratio 10.0 None 10.1128/aac.00647-07
Escherichia coli Escherichia coli Ratio 16.0 None 10.1128/aac.00927-10
Escherichia coli Escherichia coli Ratio 32.0 None 10.1128/aac.00927-10
Escherichia coli Escherichia coli Ratio 64.0 None 10.1128/aac.00927-10
Escherichia coli Escherichia coli Ratio 66.7 None 10.1128/aac.00927-10
Escherichia coli Escherichia coli Ratio 250.0 None 10.1128/aac.00927-10
Escherichia coli Escherichia coli TIME 24.0 hr 10.1128/aac.00927-10
Escherichia coli Escherichia coli TIME 48.0 hr 10.1128/aac.00927-10
Escherichia coli LexA repressor FC 5.0 None 10.1021/acs.jmedchem.0c00328
Escherichia coli K-12 Cell division inhibitor sulA FC 17.0 None 10.1021/acs.jmedchem.0c00328
Escherichia coli K-12 Recombinase A FC 20.0 None 10.1021/acs.jmedchem.0c00328
Eubacterium sp. Eubacterium sp. Activity 0.0 % 10.1128/aac.00481-10
Eubacterium sp. Eubacterium sp. Activity 92.0 % 10.1128/aac.00481-10
Eubacterium sp. Eubacterium sp. MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Eubacterium sp. Eubacterium sp. MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Eubacterium sp. Eubacterium sp. MIC90 2.0 ug.mL-1 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna Activity 13.0 % 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna Activity 27.0 % 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna Activity 40.0 % 10.1128/aac.00696-08
Finegoldia magna Finegoldia magna Activity 60.0 % 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna Activity 78.0 % 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna MIC 0.25 ug.mL-1 10.1128/aac.00696-08
Finegoldia magna Finegoldia magna MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna MIC50 0.5 ug.mL-1 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna MIC50 4.0 ug.mL-1 10.1128/aac.00696-08
Finegoldia magna Finegoldia magna MIC90 8.0 ug.mL-1 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna MIC90 8.0 ug.mL-1 10.1128/aac.00481-10
Finegoldia magna Finegoldia magna MIC90 32.0 ug.mL-1 10.1128/aac.00696-08
Fusarium solani Fusarium solani MIC 285500.0 nM 10.1016/j.ejmech.2020.112513
Fusobacterium mortiferum Fusobacterium mortiferum Activity 0.0 % 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum Activity 81.0 % 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC 0.25 ug.mL-1 10.1128/aac.00481-10
Fusobacterium mortiferum Fusobacterium mortiferum MIC50 1.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum Activity 0.0 % 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum Activity 81.0 % 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC50 1.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum Activity 0.0 % 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum Activity 81.0 % 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC 0.25 ug.mL-1 10.1128/aac.00481-10
Fusobacterium nucleatum Fusobacterium nucleatum MIC50 1.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium sp. Fusobacterium sp. Activity 95.2 % 10.1128/aac.00418-09
Fusobacterium sp. Fusobacterium sp. MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Fusobacterium sp. Fusobacterium sp. MIC50 1.0 ug.mL-1 10.1128/aac.00418-09
Fusobacterium sp. Fusobacterium sp. MIC90 2.0 ug.mL-1 10.1128/aac.00418-09
Fusobacterium varium Fusobacterium varium Activity 0.0 % 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium Activity 81.0 % 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium MIC 0.25 ug.mL-1 10.1128/aac.00481-10
Fusobacterium varium Fusobacterium varium MIC50 1.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Haemophilus influenzae Haemophilus influenzae Activity 9.1 ug ml-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae Activity 100.0 ug ml-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC 0.008 ug.mL-1 10.1128/aac.01374-09
Haemophilus influenzae Haemophilus influenzae MIC 0.012 ug.mL-1 10.1021/acs.jmedchem.8b00644
Haemophilus influenzae Haemophilus influenzae MIC 0.012 ug.mL-1 10.1021/jm301650g
Haemophilus influenzae Haemophilus influenzae MIC 0.013 ug.mL-1 10.1016/j.bmcl.2005.11.064
Haemophilus influenzae Haemophilus influenzae MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC 0.015 ug.mL-1 10.1128/aac.01197-09
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1016/j.bmc.2010.06.098
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1016/j.bmc.2011.03.018
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1128/aac.01437-06
Haemophilus influenzae Haemophilus influenzae MIC 0.06 ug.mL-1 10.1128/aac.01437-06
Haemophilus influenzae Haemophilus influenzae MIC 0.12 ug.mL-1 10.1128/aac.01437-06
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.01437-06
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.00723-10
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.01437-06
Haemophilus influenzae Haemophilus influenzae MIC 1.0 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1128/aac.01437-06
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1128/aac.01437-06
Haemophilus influenzae Haemophilus influenzae MIC50 0.015 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.015 ug.mL-1 10.1128/aac.01374-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.25 ug.mL-1 10.1128/aac.01197-09
Haemophilus influenzae Haemophilus influenzae MIC50 2.0 ug.mL-1 10.1128/aac.00723-10
Haemophilus influenzae Haemophilus influenzae MIC50 8.0 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC90 0.03 ug.mL-1 10.1128/aac.01374-09
Haemophilus influenzae Haemophilus influenzae MIC90 0.06 ug.mL-1 10.1039/C9MD00120D
Haemophilus influenzae Haemophilus influenzae MIC90 0.06 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC90 8.0 ug.mL-1 10.1128/aac.00723-10
Haemophilus influenzae Haemophilus influenzae MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Haemophilus influenzae Haemophilus influenzae MIC90 16.0 ug.mL-1 10.1128/aac.00418-09
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 1000000.0 nM 10.1124/dmd.112.047068
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 AC50 300000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cytochrome P450 3A4 Activity 97.9 % 10.1021/acs.jmedchem.8b00644
Homo sapiens Delta opioid receptor AC50 299999.1 nM 10.1038/s41467-023-40064-9
Homo sapiens DNA topoisomerase II alpha EC2 150.0 uM 10.1021/jm060844e
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A AC50 300000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 AC50 300000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HeLa CC50 nan None 10.1021/jm2002124
Homo sapiens HeLa IC20 40.0 ug ml-1 10.1128/aac.00729-05
Homo sapiens HeLa IC20 90.0 ug ml-1 10.1128/aac.00729-05
Homo sapiens HeLa IC50 110.0 ug.mL-1 10.1128/aac.00729-05
Homo sapiens HeLa IC50 320.0 ug.mL-1 10.1128/aac.00729-05
Homo sapiens HeLa IC50 320000.0 nM 10.1016/j.bmc.2009.06.053
Homo sapiens HEp-2 CC50 100000.0 nM 10.1016/j.bmcl.2005.11.064
Homo sapiens HEp-2 CC50 100000.0 nM 10.1016/j.bmcl.2005.11.065
Homo sapiens HEp-2 CC50 100000.0 nM 10.1021/jm101604v
Homo sapiens HEp-2 CC50 100000.0 nM 10.1021/jm2002124
Homo sapiens HepG2 CC50 100000.0 nM 10.1021/jm060844e
Homo sapiens HepG2 CC50 nan None 10.1021/jm2002124
Homo sapiens HepG2 EC50 100000.0 nM 10.1021/acs.jmedchem.1c00375
Homo sapiens HepG2 IC50 50000.0 nM 10.1021/acs.jmedchem.2c00266
Homo sapiens HERG AC50 25000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 30000.0 nM 10.1021/jm2002124
Homo sapiens HERG IC50 79432.82 nM 10.1016/j.vascn.2014.07.002
Homo sapiens HERG IC50 117489.76 nM 10.1016/j.bmcl.2005.01.008
Homo sapiens HERG IC50 117489.76 nM 10.1016/j.ejmech.2008.11.009
Homo sapiens HERG IC50 128824.96 nM 10.1016/j.bmc.2008.04.028
Homo sapiens HERG IC50 128824.96 nM 10.1016/j.bmcl.2005.03.080
Homo sapiens HERG IC50 128824.96 nM 10.1016/j.ejmech.2010.11.042
Homo sapiens HERG IC50 128824.96 nM 10.1016/s0960-894x(03)00492-x
Homo sapiens HERG IC50 129000.0 nM 10.1016/j.bmcl.2013.04.074
Homo sapiens HERG IC50 129000.0 nM 10.1021/acs.jmedchem.1c00375
Homo sapiens HERG IC50 129000.0 nM 10.1021/jm0208875
Homo sapiens HERG IC50 398107.17 nM 10.1016/j.vascn.2014.07.002
Homo sapiens HERG INH 129.0 uM 10.1016/j.bmcl.2020.127428
Homo sapiens HERG Inhibition 10.0 % 10.1021/jm2002124
Homo sapiens HERG Inhibition 21.5 % 10.1021/jm301650g
Homo sapiens HERG Inhibition 22.0 % 10.1021/acs.jmedchem.8b00644
Homo sapiens HERG Inhibition 42.0 % 10.1021/acs.jmedchem.8b00644
Homo sapiens HERG Inhibition 42.3 % 10.1021/jm301650g
Homo sapiens HERG pIC50 nan None 10.1016/j.vascn.2014.07.002
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone deacetylase 6 Inhibition -8.76 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition 12.48 % 10.6019/CHEMBL4808148
Homo sapiens Homo sapiens Activity 0.0 % 10.1128/aac.01447-09
Homo sapiens Homo sapiens Activity 3.0 % 10.1128/aac.01447-09
Homo sapiens Homo sapiens Activity 5.0 % 10.1128/aac.01447-09
Homo sapiens Homo sapiens Activity nan None 10.1128/aac.00554-08
Homo sapiens Homo sapiens Activity nan None 10.1128/aac.01447-09
Homo sapiens Homo sapiens Activity nan None 10.1128/aac.01637-07
Homo sapiens Homo sapiens AUC 3960.0 ng.hr.mL-1 10.1128/aac.01372-06
Homo sapiens Homo sapiens AUC 19780.0 ng.hr.mL-1 10.1128/aac.01372-06
Homo sapiens Homo sapiens AUC 25500.0 ng.hr.mL-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens AUC 26810.0 ng.hr.mL-1 10.1128/aac.01372-06
Homo sapiens Homo sapiens AUC 26900.0 ng.hr.mL-1 10.1128/aac.00749-08
Homo sapiens Homo sapiens AUC 26900.0 ng.hr.mL-1 10.1128/aac.01123-07
Homo sapiens Homo sapiens AUC 29200.0 ng.hr.mL-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens AUC 30300.0 ng.hr.mL-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens AUC 34400.0 ng.hr.mL-1 10.1128/aac.00554-08
Homo sapiens Homo sapiens AUC 35000.0 ng.hr.mL-1 10.1128/aac.01520-06
Homo sapiens Homo sapiens AUC 37200.0 ng.hr.mL-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens AUC 39000.0 ng.hr.mL-1 10.1016/j.ejmech.2012.02.033
Homo sapiens Homo sapiens AUC 39400.0 ng.hr.mL-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens AUC 39700.0 ng.hr.mL-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens AUC 41900.0 ng.hr.mL-1 10.1128/aac.00554-08
Homo sapiens Homo sapiens AUC 369900.0 ng.hr.mL-1 10.1128/aac.00554-08
Homo sapiens Homo sapiens AUC 461700.0 ng.hr.mL-1 10.1128/aac.00554-08
Homo sapiens Homo sapiens CL 1.9 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 2.4 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL 2.4 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 10.7 L/hr 10.1128/aac.01056-08
Homo sapiens Homo sapiens CL 10.8 L/hr 10.1128/aac.01056-08
Homo sapiens Homo sapiens CL 14.3 L/hr 10.1128/aac.01761-09
Homo sapiens Homo sapiens CL 18.9 L/hr 10.1128/aac.01056-08
Homo sapiens Homo sapiens CL 20.0 L/hr 10.1128/aac.01056-08
Homo sapiens Homo sapiens CL 96.0 ml/min 10.1128/aac.01036-07
Homo sapiens Homo sapiens CL/F 7.89 L/hr 10.1128/aac.00554-08
Homo sapiens Homo sapiens CL/F 10.1 L/hr 10.1128/aac.00554-08
Homo sapiens Homo sapiens CL_renal 0.5 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL_renal 0.53 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens Cmax 822.04 nM 10.1128/aac.01372-06
Homo sapiens Homo sapiens Cmax 4060.38 nM 10.1128/aac.01372-06
Homo sapiens Homo sapiens Cmax 5978.48 nM 10.1128/aac.01372-06
Homo sapiens Homo sapiens Cmax 6227.58 nM 10.1128/aac.00749-08
Homo sapiens Homo sapiens Cmax 6227.58 nM 10.1128/aac.01123-07
Homo sapiens Homo sapiens Cmax 6227.58 nM 10.1128/aac.01520-06
Homo sapiens Homo sapiens Cmax 8295.14 nM 10.1128/aac.00554-08
Homo sapiens Homo sapiens Cmax 10711.44 nM 10.1016/j.ejmech.2012.02.033
Homo sapiens Homo sapiens Cmax 11134.91 nM 10.1128/aac.01036-07
Homo sapiens Homo sapiens Cmax 12455.16 nM 10.1128/aac.01253-08
Homo sapiens Homo sapiens Cmax 100388.6 nM 10.1128/aac.00554-08
Homo sapiens Homo sapiens Cp 2.94 ug ml-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens Cp 3.53 ug ml-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens Cp 3.6 ug ml-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens Cp 3.8 ug ml-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens Cp 3.81 ug ml-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens Cp 3.83 ug ml-1 10.1128/aac.01621-06
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 8.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens F 86.0 % 10.1128/aac.00749-08
Homo sapiens Homo sapiens F 90.0 % 10.1016/j.bmc.2007.08.060
Homo sapiens Homo sapiens F 90.0 % 10.1016/j.ejmech.2012.02.033
Homo sapiens Homo sapiens Fa 0.9 None 10.1021/jm901371v
Homo sapiens Homo sapiens F_fraction 0.86 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fg 1.04 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fh 0.92 None 10.1021/jm901371v
Homo sapiens Homo sapiens Ratio 0.81 None 10.1128/aac.00554-08
Homo sapiens Homo sapiens Ratio 0.85 None 10.1128/aac.00554-08
Homo sapiens Homo sapiens Ratio 1.06 None 10.1128/aac.00554-08
Homo sapiens Homo sapiens Ratio 1.12 None 10.1128/aac.00554-08
Homo sapiens Homo sapiens Ratio 1.3 None 10.1128/aac.00554-08
Homo sapiens Homo sapiens Ratio AUC 0.83 None 10.1128/aac.00554-08
Homo sapiens Homo sapiens T1/2 6.46 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens T1/2 6.5 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens T1/2 6.51 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens T1/2 8.0 hr 10.1128/aac.01520-06
Homo sapiens Homo sapiens T1/2 8.94 hr 10.1128/aac.00554-08
Homo sapiens Homo sapiens T1/2 9.1 hr 10.1016/j.ejmech.2012.02.033
Homo sapiens Homo sapiens T1/2 9.2 hr 10.1128/aac.00749-08
Homo sapiens Homo sapiens T1/2 9.77 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens T1/2 10.4 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens T1/2 10.9 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens T1/2 11.1 hr 10.1128/aac.00554-08
Homo sapiens Homo sapiens T1/2 12.0 hr 10.1007/s00044-012-0101-3
Homo sapiens Homo sapiens tCmax 1.0 hr 10.1128/aac.01520-06
Homo sapiens Homo sapiens TIME 2.778e-06 hr 10.1128/aac.01447-09
Homo sapiens Homo sapiens Tmax 1.0 hr 10.1016/j.ejmech.2012.02.033
Homo sapiens Homo sapiens Tmax 1.0 hr 10.1128/aac.00749-08
Homo sapiens Homo sapiens Tmax 1.05 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens Tmax 1.47 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens Tmax 1.56 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens Tmax 1.91 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens Tmax 1.97 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens Tmax 1.98 hr 10.1128/aac.01621-06
Homo sapiens Homo sapiens Tmax 2.0 hr 10.1128/aac.01036-07
Homo sapiens Homo sapiens Tmax 2.37 hr 10.1128/aac.00554-08
Homo sapiens Homo sapiens Tmax 2.6 hr 10.1128/aac.00554-08
Homo sapiens Homo sapiens Tmax 10.8 hr 10.1128/aac.00554-08
Homo sapiens Homo sapiens Tmax 24.9 hr 10.1128/aac.00554-08
Homo sapiens Homo sapiens Vd 45.2 l 10.1128/aac.01056-08
Homo sapiens Homo sapiens Vd 58.6 l 10.1128/aac.01056-08
Homo sapiens Homo sapiens Vd 59.5 l 10.1128/aac.01056-08
Homo sapiens Homo sapiens Vd 62.0 l 10.1128/aac.01056-08
Homo sapiens Homo sapiens Vd 62.91 l 10.1128/aac.01761-09
Homo sapiens Homo sapiens Vd 120.8 l 10.1128/aac.00554-08
Homo sapiens Homo sapiens Vd 127.4 l 10.1128/aac.00554-08
Homo sapiens Homo sapiens Vdss 1.4 L.kg-1 10.1021/jm901371v
Homo sapiens K562 EC50 100000.0 nM 10.1021/acs.jmedchem.1c00375
Homo sapiens Kappa opioid receptor AC50 320.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MG-63 IC20 30.0 ug ml-1 10.1128/aac.00729-05
Homo sapiens MG-63 IC20 110.0 ug ml-1 10.1128/aac.00729-05
Homo sapiens MG-63 IC50 170.0 ug.mL-1 10.1128/aac.00729-05
Homo sapiens MG-63 IC50 230.0 ug.mL-1 10.1128/aac.00729-05
Homo sapiens MG-63 IC50 230000.0 nM 10.1016/j.bmc.2009.06.053
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Motilin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MRC5 IC50 100.0 ug.mL-1 10.1016/j.ejmech.2022.114404
Homo sapiens MRC5 IC50 10900.0 nM 10.1016/j.bmcl.2004.03.070
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 8199.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 300000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 219998.6 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Plasma Cmax 9964.13 nM 10.1128/aac.01145-08
Homo sapiens Plasma Drug uptake 1.0 ug ml-1 10.1128/aac.01023-08
Homo sapiens Plasma Fu 0.5 None 10.1128/aac.01145-08
Homo sapiens Plasma PPB 47.8 % 10.1021/jm301650g
Homo sapiens Plasma PPB 50.0 % 10.1128/aac.00749-08
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serum Fu 0.47 None 10.1128/aac.01372-06
Homo sapiens Serum albumin PPB 1.3 % 10.1021/acs.jmedchem.8b00644
Homo sapiens Sodium channel protein type V alpha subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Sodium channel protein type V alpha subunit IC50 39810.72 nM 10.1016/j.vascn.2014.07.002
Homo sapiens Sodium channel protein type V alpha subunit IC50 251188.64 nM 10.1016/j.vascn.2014.07.002
Homo sapiens THP-1 CL 14.55 L/hr 10.1128/aac.01761-09
Homo sapiens THP-1 T1/2 12.05 hr 10.1128/aac.01761-09
Homo sapiens THP-1 Vd 251.9 l 10.1128/aac.01761-09
Homo sapiens Thromboxane A2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Voltage-gated L-type calcium channel IC50 173000.0 nM 10.1038/srep02100
Homo sapiens Voltage-gated L-type calcium channel alpha-1C subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Voltage-gated L-type calcium channel alpha-1C subunit IC50 168900.0 nM 10.1002/jat.2784
Homo sapiens Voltage-gated L-type calcium channel alpha-1C subunit IC50 398107.17 nM 10.1016/j.vascn.2014.07.002
Homo sapiens Voltage-gated L-type calcium channel alpha-1C subunit pIC50 nan None 10.1016/j.vascn.2014.07.002
Homo sapiens Voltage-gated potassium channel, IKs; KCNQ1(Kv7.1)/KCNE1(MinK) IC50 158489.32 nM 10.1016/j.vascn.2014.07.002
Homo sapiens Voltage-gated potassium channel, IKs; KCNQ1(Kv7.1)/KCNE1(MinK) IC50 398107.17 nM 10.1016/j.vascn.2014.07.002
Homo sapiens Voltage-gated potassium channel subunit Kv4.3 pIC50 nan None 10.1016/j.vascn.2014.07.002
Hoylesella oralis Hoylesella oralis Activity 11.0 % 10.1128/aac.00481-10
Hoylesella oralis Hoylesella oralis Activity 56.0 % 10.1128/aac.00481-10
Hoylesella oralis Hoylesella oralis MIC 0.5 ug.mL-1 10.1128/aac.00481-10
Hoylesella oralis Hoylesella oralis MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Hoylesella oralis Hoylesella oralis MIC90 8.0 ug.mL-1 10.1128/aac.00481-10
Klebsiella Klebsiella MIC90 0.12 ug.mL-1 10.1039/C9MD00120D
Klebsiella aerogenes Klebsiella aerogenes Activity 80.0 % 10.1128/aac.00418-09
Klebsiella aerogenes Klebsiella aerogenes MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Klebsiella aerogenes Klebsiella aerogenes MIC 0.03 ug.mL-1 10.1128/aac.01374-09
Klebsiella aerogenes Klebsiella aerogenes MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Klebsiella aerogenes Klebsiella aerogenes MIC50 0.12 ug.mL-1 10.1128/aac.01374-09
Klebsiella aerogenes Klebsiella aerogenes MIC90 0.25 ug.mL-1 10.1128/aac.01374-09
Klebsiella aerogenes Klebsiella aerogenes MIC90 16.0 ug.mL-1 10.1128/aac.00418-09
Klebsiella oxytoca Klebsiella oxytoca Activity 46.9 % 10.1128/aac.00078-09
Klebsiella oxytoca Klebsiella oxytoca Activity 93.8 % 10.1128/aac.00078-09
Klebsiella oxytoca Klebsiella oxytoca Activity 100.0 % 10.1128/aac.00078-09
Klebsiella oxytoca Klebsiella oxytoca Activity nan None 10.1128/aac.00418-09
Klebsiella oxytoca Klebsiella oxytoca MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Klebsiella oxytoca Klebsiella oxytoca MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Klebsiella oxytoca Klebsiella oxytoca MIC90 2.0 ug.mL-1 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 24.1 % 10.1128/aac.00078-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 72.4 % 10.1128/aac.00078-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 77.9 % 10.1128/aac.00078-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 83.9 % 10.1128/aac.00078-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 90.0 % 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 91.5 % 10.1128/aac.00078-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 93.0 % 10.1128/aac.00078-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 94.5 % 10.1128/aac.00078-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 96.0 % 10.1128/aac.00078-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 100.0 % 10.1128/aac.00078-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.008 ug.mL-1 10.1021/jm050035f
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.015 ug.mL-1 10.1016/j.ejmech.2014.09.029
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01374-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.025 ug.mL-1 10.1021/jm020328y
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.03 ug.mL-1 10.1016/j.ejmech.2011.10.048
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.03 ug.mL-1 10.1016/j.ejmech.2014.09.029
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.031 ug.mL-1 10.1016/j.bmcl.2005.11.064
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.05 ug.mL-1 10.1016/j.bmc.2009.08.026
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.05 ug.mL-1 10.1016/j.bmcl.2004.07.064
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1016/j.ejmech.2014.09.029
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01534-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.1 ug.mL-1 10.1021/acs.jmedchem.8b00644
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.1 ug.mL-1 10.1021/jm301650g
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01197-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01534-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1016/j.ejmech.2011.10.048
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1016/j.ejmech.2014.09.029
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1016/j.ejmech.2011.03.026
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01534-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00726-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00841-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01534-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.01374-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01197-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01374-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00418-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 3.9 ug.mL-1 10.1016/j.bmcl.2017.01.073
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Klebsiella pneumoniae Klebsiella pneumoniae MPC 4.0 ug ml-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MPC 16.0 ug ml-1 10.1128/aac.01444-06
Klebsiella pneumoniae Klebsiella pneumoniae MPC 32.0 ug ml-1 10.1128/aac.01444-06
Lactococcus lactis Lactococcus lactis MIC 0.25 ug.mL-1 10.1128/aac.00274-07
Lactococcus lactis Lactococcus lactis MIC 1.0 ug.mL-1 10.1128/aac.00274-07
Legionella pneumophila Legionella pneumophila Activity nan None 10.1128/aac.00418-09
Legionella pneumophila Legionella pneumophila MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Legionella pneumophila Legionella pneumophila MIC50 0.03 ug.mL-1 10.1128/aac.00418-09
Legionella pneumophila Legionella pneumophila MIC90 0.06 ug.mL-1 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes Activity 100.0 % 10.1128/aac.00177-08
Listeria monocytogenes Listeria monocytogenes Activity nan None 10.1128/aac.00177-08
Listeria monocytogenes Listeria monocytogenes Activity nan None 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes Activity nan None 10.1128/aac.00845-09
Listeria monocytogenes Listeria monocytogenes Activity nan None 10.1128/aac.01211-07
Listeria monocytogenes Listeria monocytogenes FC 1.0 None 10.1128/aac.00177-08
Listeria monocytogenes Listeria monocytogenes log10CFU/ml 3.0 None 10.1128/aac.01211-07
Listeria monocytogenes Listeria monocytogenes MIC 0.12 ug.mL-1 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes MIC 0.5 ug.mL-1 10.1128/aac.00845-09
Listeria monocytogenes Listeria monocytogenes MIC 0.6 ug.mL-1 10.1016/j.ejmech.2021.113741
Listeria monocytogenes Listeria monocytogenes MIC 500.0 nM 10.1016/j.ejmech.2020.112513
Listeria monocytogenes Listeria monocytogenes MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes MIC50 0.5 ug.mL-1 10.1128/aac.00845-09
Listeria monocytogenes Listeria monocytogenes MIC90 0.5 ug.mL-1 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes MIC90 1.0 ug.mL-1 10.1128/aac.00845-09
Listeria monocytogenes Listeria monocytogenes MIC90 3.9 ug.mL-1 10.1016/j.bmcl.2017.01.073
Listeria monocytogenes Listeria monocytogenes TIME 24.0 hr 10.1128/aac.00177-08
Metamycoplasma hominis Metamycoplasma hominis MIC 0.032 ug.mL-1 10.1128/aac.00849-08
Metamycoplasma hominis Metamycoplasma hominis MIC 0.063 ug.mL-1 10.1128/aac.00746-09
Metamycoplasma hominis Metamycoplasma hominis MIC50 0.06 ug.mL-1 10.1128/aac.00746-09
Metamycoplasma hominis Metamycoplasma hominis MIC50 0.063 ug.mL-1 10.1128/aac.00849-08
Metamycoplasma hominis Metamycoplasma hominis MIC90 0.06 ug.mL-1 10.1128/aac.00746-09
Metamycoplasma hominis Metamycoplasma hominis MIC90 0.063 ug.mL-1 10.1128/aac.00849-08
Moraxella catarrhalis Moraxella catarrhalis Activity nan None 10.1128/aac.00418-09
Moraxella catarrhalis Moraxella catarrhalis MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Moraxella catarrhalis Moraxella catarrhalis MIC 0.05 ug.mL-1 10.1021/acs.jmedchem.8b00644
Moraxella catarrhalis Moraxella catarrhalis MIC 0.05 ug.mL-1 10.1021/jm301650g
Moraxella catarrhalis Moraxella catarrhalis MIC 0.06 ug.mL-1 10.1128/aac.01374-09
Moraxella catarrhalis Moraxella catarrhalis MIC 0.061 ug.mL-1 10.1016/j.bmcl.2005.11.064
Moraxella catarrhalis Moraxella catarrhalis MIC 32.0 ug.mL-1 10.1128/aac.00723-10
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.03 ug.mL-1 10.1128/aac.00418-09
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.06 ug.mL-1 10.1128/aac.01374-09
Moraxella catarrhalis Moraxella catarrhalis MIC50 32.0 ug.mL-1 10.1128/aac.00723-10
Moraxella catarrhalis Moraxella catarrhalis MIC90 0.03 ug.mL-1 10.1128/aac.00418-09
Moraxella catarrhalis Moraxella catarrhalis MIC90 0.06 ug.mL-1 10.1128/aac.01374-09
Moraxella catarrhalis Moraxella catarrhalis MIC90 32.0 ug.mL-1 10.1128/aac.00723-10
Morganella morganii Morganella morganii Activity nan None 10.1128/aac.00418-09
Morganella morganii Morganella morganii MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Morganella morganii Morganella morganii MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Morganella morganii Morganella morganii MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Mus musculus Brain AUC 2.9 ug.hr/g 10.1128/aac.00177-08
Mus musculus Brain Cmax 1.92 ug/g 10.1128/aac.00177-08
Mus musculus J774.A1 IC50 14.56 ug.mL-1 10.1016/j.ejmech.2022.114404
Mus musculus Mus musculus Activity nan None 10.1021/acs.jmedchem.8b00172
Mus musculus Mus musculus AUC 640.0 ng.hr.mL-1 10.1021/acs.jmedchem.8b00114
Mus musculus Mus musculus AUC 7032.0 ng.hr.mL-1 10.1016/j.ejmech.2017.11.090
Mus musculus Mus musculus AUC 25000.0 ng.hr.mL-1 10.1128/aac.00414-06
Mus musculus Mus musculus AUC 27100.0 ng.hr.mL-1 10.1128/aac.00177-08
Mus musculus Mus musculus AUC 27400.0 ng.hr.mL-1 10.1128/aac.01123-07
Mus musculus Mus musculus AUC/dose nan None 10.1021/acsmedchemlett.5b00266
Mus musculus Mus musculus CL 72.0 mL.min-1.kg-1 10.1021/acs.jmedchem.8b00114
Mus musculus Mus musculus CL nan None 10.1021/acsmedchemlett.5b00266
Mus musculus Mus musculus Cmax 946.59 nM 10.1128/aac.00414-06
Mus musculus Mus musculus Cmax 6803.01 nM 10.1016/j.ejmech.2017.11.090
Mus musculus Mus musculus Cmax 10711.44 nM 10.1128/aac.01023-08
Mus musculus Mus musculus Cmax 43094.86 nM 10.1128/aac.00177-08
Mus musculus Mus musculus Drug uptake 9.6 ug ml-1 10.1128/aac.00897-07
Mus musculus Mus musculus Drug uptake 19.6 ug ml-1 10.1128/aac.00897-07
Mus musculus Mus musculus ED50 0.6 mg.kg-1 10.1021/jm050035f
Mus musculus Mus musculus ED50 29.97 mg.kg-1 10.1021/jm050035f
Mus musculus Mus musculus ED50 66.12 mg.kg-1 10.1021/jm050035f
Mus musculus Mus musculus F nan % 10.1021/acs.jmedchem.8b00114
Mus musculus Mus musculus Inhibition nan % 10.1016/j.bmc.2016.09.012
Mus musculus Mus musculus LD50 600.0 mg.kg-1 10.1128/aac.00414-06
Mus musculus Mus musculus Survival 83.0 % 10.1021/acs.jmedchem.8b00114
Mus musculus Mus musculus Survival 100.0 % 10.1021/acs.jmedchem.8b00114
Mus musculus Mus musculus t1/2 nan None 10.1021/acsmedchemlett.5b00266
Mus musculus Mus musculus T1/2 1.0 hr 10.1128/aac.01123-07
Mus musculus Mus musculus T1/2 1.8 hr 10.1021/acs.jmedchem.8b00114
Mus musculus Mus musculus T1/2 4.46 hr 10.1128/aac.00414-06
Mus musculus Mus musculus T1/2 11.35 hr 10.1016/j.ejmech.2017.11.090
Mus musculus Mus musculus Tmax 1.08 hr 10.1016/j.ejmech.2017.11.090
Mus musculus Mus musculus T>MIC 0.0 % 10.1128/aac.00414-06
Mus musculus Mus musculus Vdss 3.7 L.kg-1 10.1021/acs.jmedchem.8b00114
Mus musculus Mus musculus Vdss nan None 10.1021/acsmedchemlett.5b00266
Mus musculus NIH3T3 IC50 379.82 ug.mL-1 10.1016/j.bmcl.2017.01.073
Mus musculus Plasma Fu 0.077 None 10.1128/aac.00414-06
Mus musculus RAW264.7 GI nan None 10.1016/j.bmc.2015.03.004
Mus musculus RAW264.7 Inhibition 1.26 % 10.1016/j.bmc.2016.01.011
Mus musculus RAW264.7 Inhibition nan % 10.1016/j.bmc.2014.06.041
Mus musculus RAW264.7 Inhibition nan % 10.1016/j.bmc.2015.11.039
Mus musculus RAW264.7 Inhibition nan % 10.1016/j.ejmech.2014.08.018
Mus musculus RAW264.7 Inhibition nan % 10.1016/j.ejmech.2014.12.046
Mus musculus RAW264.7 Inhibition nan % 10.1016/j.ejmech.2015.06.032
Mus musculus Serum Drug uptake 7.8 ug ml-1 10.1007/s00044-012-0101-3
Mus musculus Serum Drug uptake 8.0 ug ml-1 10.1128/aac.01123-07
Mycobacterium avium Mycobacterium avium log10cfu 8.83 None 10.1128/aac.00410-07
Mycobacterium avium Mycobacterium avium log10cfu 9.18 None 10.1128/aac.00410-07
Mycobacterium avium Mycobacterium avium log10cfu 9.68 None 10.1128/aac.00410-07
Mycobacterium avium Mycobacterium avium MIC 1.0 ug.mL-1 10.1128/aac.01545-09
Mycobacterium avium Mycobacterium avium MIC 1.0 ug.mL-1 10.1128/aac.01761-09
Mycobacterium avium Mycobacterium avium MIC 2.0 ug.mL-1 10.1128/aac.00410-07
Mycobacterium avium Mycobacterium avium MIC 6100.0 nM 10.1016/j.bmcl.2014.05.062
Mycobacterium avium Mycobacterium avium MIC50 2.0 ug.mL-1 10.1128/aac.01545-09
Mycobacterium avium Mycobacterium avium MIC90 4.0 ug.mL-1 10.1128/aac.01545-09
Mycobacterium avium Mycobacterium avium MIC90 600.0 nM 10.1021/acsmedchemlett.1c00549
Mycobacterium avium complex sp. Mycobacterium avium complex sp. log10cfu 5.35 None 10.1128/aac.00410-07
Mycobacterium avium complex sp. Mycobacterium avium complex sp. log10cfu 5.79 None 10.1128/aac.00410-07
Mycobacterium avium complex sp. Mycobacterium avium complex sp. log10cfu 6.53 None 10.1128/aac.00410-07
Mycobacterium avium complex sp. Mycobacterium avium complex sp. log10cfu 6.6 None 10.1128/aac.00410-07
Mycobacterium avium complex sp. Mycobacterium avium complex sp. log10cfu 7.09 None 10.1128/aac.00410-07
Mycobacterium avium complex sp. Mycobacterium avium complex sp. log10cfu 7.39 None 10.1128/aac.00410-07
Mycobacterium avium complex sp. Mycobacterium avium complex sp. log10cfu 7.78 None 10.1128/aac.00410-07
Mycobacterium avium complex sp. Mycobacterium avium complex sp. log10cfu 7.9 None 10.1128/aac.00410-07
Mycobacterium avium complex sp. Mycobacterium avium complex sp. MIC 0.5 ug.mL-1 10.1128/aac.00410-07
Mycobacterium avium complex sp. Mycobacterium avium complex sp. MIC90 2.0 ug.mL-1 10.1128/aac.00410-07
Mycobacterium intracellulare Mycobacterium intracellulare log10cfu 4.15 None 10.1128/aac.00410-07
Mycobacterium intracellulare Mycobacterium intracellulare log10cfu 4.76 None 10.1128/aac.00410-07
Mycobacterium intracellulare Mycobacterium intracellulare log10cfu 4.83 None 10.1128/aac.00410-07
Mycobacterium intracellulare Mycobacterium intracellulare MIC 0.5 ug.mL-1 10.1128/aac.00410-07
Mycobacterium intracellulare Mycobacterium intracellulare MIC 0.5 ug.mL-1 10.1128/aac.01545-09
Mycobacterium intracellulare Mycobacterium intracellulare MIC50 2.0 ug.mL-1 10.1128/aac.01545-09
Mycobacterium intracellulare Mycobacterium intracellulare MIC90 8.0 ug.mL-1 10.1128/aac.01545-09
Mycobacterium kansasii Mycobacterium kansasii MIC 0.06 ug.mL-1 10.1128/aac.01545-09
Mycobacterium kansasii Mycobacterium kansasii MIC 120.0 nM 10.1016/j.bmcl.2014.05.062
Mycobacterium kansasii Mycobacterium kansasii MIC50 0.125 ug.mL-1 10.1128/aac.01545-09
Mycobacterium kansasii Mycobacterium kansasii MIC90 0.25 ug.mL-1 10.1128/aac.01545-09
Mycobacterium leprae Mycobacterium leprae Activity 99.0 % 10.1128/aac.01282-06
Mycobacterium leprae Mycobacterium leprae Activity nan None 10.1128/aac.01282-06
Mycobacterium leprae Mycobacterium leprae CC25 0.7 ug ml-1 10.1128/aac.01095-07
Mycobacterium leprae Mycobacterium leprae CC25 0.8 ug ml-1 10.1128/aac.01095-07
Mycobacterium leprae Mycobacterium leprae CC25 2.0 ug ml-1 10.1016/j.bmc.2012.12.011
Mycobacterium leprae Mycobacterium leprae CC25 2.0 ug ml-1 10.1128/aac.01282-06
Mycobacterium leprae Mycobacterium leprae CC25 12.0 ug ml-1 10.1016/j.bmc.2012.12.011
Mycobacterium leprae Mycobacterium leprae CC25 12.0 ug ml-1 10.1128/aac.01095-07
Mycobacterium leprae Mycobacterium leprae CC25 nan None 10.1016/j.bmc.2012.12.011
Mycobacterium leprae Mycobacterium leprae CC25 nan None 10.1128/aac.01095-07
Mycobacterium leprae Mycobacterium leprae FC 3.0 None 10.1128/aac.01095-07
Mycobacterium leprae Mycobacterium leprae FC 5.0 None 10.1128/aac.01095-07
Mycobacterium leprae Mycobacterium leprae FC 12.0 None 10.1128/aac.01095-07
Mycobacterium leprae Mycobacterium leprae IC50 2.0 ug.mL-1 10.1016/j.bmc.2012.12.011
Mycobacterium leprae Mycobacterium leprae IC50 2.0 ug.mL-1 10.1128/aac.01282-06
Mycobacterium leprae Mycobacterium leprae IC50 6.0 ug.mL-1 10.1128/aac.01095-07
Mycobacterium leprae Mycobacterium leprae IC50 25.0 ug.mL-1 10.1128/aac.01095-07
Mycobacterium leprae Mycobacterium leprae IC50 30.0 ug.mL-1 10.1128/aac.01095-07
Mycobacterium marinum Mycobacterium marinum Activity 2.9 deltalog10CFU/ml 10.1016/j.bmc.2016.01.059
Mycobacterium marinum Mycobacterium marinum IC50 140.0 nM 10.1016/j.ejmech.2019.07.052
Mycobacterium marinum Mycobacterium marinum log(activity) 2.4 None 10.1016/j.ejmech.2017.12.088
Mycobacterium marinum Mycobacterium marinum log(activity) 2.5 None 10.1016/j.bmc.2017.11.031
Mycobacterium marinum Mycobacterium marinum log(activity) 2.7 None 10.1016/j.bmc.2017.03.053
Mycobacterium marinum Mycobacterium marinum MIC 12400.0 nM 10.1016/j.bmcl.2014.05.062
Mycobacterium smegmatis DNA gyrase subunit B IC50 50000.0 nM 10.1016/j.bmc.2014.06.041
Mycobacterium smegmatis DNA gyrase subunit B IC50 50000.0 nM 10.1016/j.bmc.2015.03.004
Mycobacterium smegmatis DNA gyrase subunit B IC50 50000.0 nM 10.1016/j.ejmech.2015.06.032
Mycobacterium tuberculosis DNA gyrase subunit A IC50 9200.0 nM 10.1128/aac.00287-10
Mycobacterium tuberculosis DNA gyrase subunit A IC50 31000.0 nM 10.1128/aac.00287-10
Mycobacterium tuberculosis DNA gyrase subunit A IC50 59000.0 nM 10.1128/aac.00287-10
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 0.11 log10CFU 10.1021/acsmedchemlett.1c00431
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 2.5 % 10.1128/aac.00897-07
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 2.54 log10CFU/ml 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 2.7 log10CFU 10.1021/acs.jmedchem.9b01561
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 3.1 log10CFU 10.1016/j.ejmech.2017.12.075
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 3.3 log10CFU 10.1021/acs.jmedchem.0c00107
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 3.5 log10CFU 10.1021/acsmedchemlett.9b00204
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 3.77 log10CFU/ml 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 3.93 log10CFU/ml 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 4.0 log10CFU 10.1021/acs.jmedchem.8b00172
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 4.02 log10CFU/ml 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity 37.0 % 10.1128/aac.00749-08
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1016/j.bmc.2017.11.031
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1021/acsmedchemlett.9b00515
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1021/jm401326j
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1021/jm500432n
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1128/aac.00287-09
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1128/aac.00414-06
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1128/aac.00661-10
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1128/aac.00898-06
Mycobacterium tuberculosis Mycobacterium tuberculosis ED99 27.7 mg kg-1 10.1128/aac.01423-09
Mycobacterium tuberculosis Mycobacterium tuberculosis Emax 100.0 mg kg-1 10.1128/aac.01423-09
Mycobacterium tuberculosis Mycobacterium tuberculosis FC 1.5 None 10.1016/j.ejmech.2019.112010
Mycobacterium tuberculosis Mycobacterium tuberculosis FC 2.0 None 10.1021/acs.jnatprod.9b00475
Mycobacterium tuberculosis Mycobacterium tuberculosis FC 2.5 None 10.1016/j.ejmech.2014.12.046
Mycobacterium tuberculosis Mycobacterium tuberculosis FC 2.7 None 10.1016/j.bmc.2016.09.012
Mycobacterium tuberculosis Mycobacterium tuberculosis FC 2.8 None 10.1016/j.bmc.2016.07.051
Mycobacterium tuberculosis Mycobacterium tuberculosis FC 3.4 None 10.1016/j.bmcl.2018.07.021
Mycobacterium tuberculosis Mycobacterium tuberculosis FC 3.48 None 10.1021/jm401326j
Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 250.0 nM 10.1016/j.ejmech.2020.113021
Mycobacterium tuberculosis Mycobacterium tuberculosis Inhibition 100.0 % 10.1007/s00044-012-9971-7
Mycobacterium tuberculosis Mycobacterium tuberculosis Inhibition nan % 10.1021/acsmedchemlett.9b00515
Mycobacterium tuberculosis Mycobacterium tuberculosis LCK 2.3 None 10.1021/jm500432n
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 0.93 None 10.1128/aac.01123-07
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 2.21 None 10.1128/aac.01423-09
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 2.37 None 10.1128/aac.00897-07
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 2.43 None 10.1128/aac.00897-07
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 3.48 None 10.1128/aac.01123-07
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 4.27 None 10.1128/aac.01123-07
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 4.39 None 10.1128/aac.01123-07
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 4.4 None 10.1128/aac.01123-07
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 7.87 None 10.1128/aac.01123-07
Mycobacterium tuberculosis Mycobacterium tuberculosis log10cfu 8.61 None 10.1128/aac.01123-07
Mycobacterium tuberculosis Mycobacterium tuberculosis Log10 cfu 3.2 None 10.1128/aac.00414-06
Mycobacterium tuberculosis Mycobacterium tuberculosis Log10 cfu 4.3 None 10.1128/aac.00898-06
Mycobacterium tuberculosis Mycobacterium tuberculosis Log10 cfu 5.5 None 10.1128/aac.00898-06
Mycobacterium tuberculosis Mycobacterium tuberculosis log10CFU/ml 3.0 None 10.1128/aac.00414-06
Mycobacterium tuberculosis Mycobacterium tuberculosis log10CFU/ml/day 0.33 None 10.1016/j.ejmech.2012.02.033
Mycobacterium tuberculosis Mycobacterium tuberculosis log(activity) 0.3 None 10.1016/j.ejmech.2017.12.088
Mycobacterium tuberculosis Mycobacterium tuberculosis log(activity) 1.8 None 10.1016/j.bmc.2017.03.053
Mycobacterium tuberculosis Mycobacterium tuberculosis log(activity) 1.8 None 10.1016/j.bmc.2017.11.031
Mycobacterium tuberculosis Mycobacterium tuberculosis log(activity) 1.8 None 10.1016/j.ejmech.2020.112178
Mycobacterium tuberculosis Mycobacterium tuberculosis log(activity) 2.0 None 10.1016/j.ejmech.2017.12.088
Mycobacterium tuberculosis Mycobacterium tuberculosis log(activity) 2.0 None 10.1016/j.ejmech.2020.112178
Mycobacterium tuberculosis Mycobacterium tuberculosis log(activity) 2.2 None 10.1016/j.bmc.2017.03.053
Mycobacterium tuberculosis Mycobacterium tuberculosis log(activity) 2.8 None 10.1021/acs.jmedchem.8b00172
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.03 ug.mL-1 10.1128/aac.00287-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.04 ug.mL-1 10.1016/j.bmcl.2018.05.049
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.06 ug.mL-1 10.1021/jm500432n
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.06 ug.mL-1 10.1128/aac.00287-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.0625 ug.mL-1 10.1016/j.bmcl.2014.03.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.075 ug.mL-1 10.1016/j.ejmech.2016.11.048
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.1 ug.mL-1 10.1016/j.ejmech.2017.11.090
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.1 ug.mL-1 10.1016/j.ejmech.2018.01.080
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.1 ug.mL-1 10.1016/j.ejmech.2018.11.032
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.1 ug.mL-1 10.1021/acsmedchemlett.1c00431
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.1 ug.mL-1 10.1128/aac.00897-07
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.12 ug.mL-1 10.1016/j.ejmech.2017.11.090
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.12 ug.mL-1 10.1016/j.ejmech.2018.11.032
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.12 ug.mL-1 10.1016/j.ejmech.2019.07.057
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.12 ug.mL-1 10.1021/jm4012033
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.12 ug.mL-1 10.1128/aac.00897-07
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.125 ug.mL-1 10.1016/j.bmcl.2014.03.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.125 ug.mL-1 10.1128/aac.00287-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.125 ug.mL-1 10.1128/aac.00661-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.125 ug.mL-1 10.1128/aac.01545-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.15 ug.mL-1 10.1128/aac.01637-07
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.18 ug.mL-1 10.1016/j.ejmech.2012.02.033
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.19 ug.mL-1 10.1021/acsmedchemlett.1c00431
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.2 ug.mL-1 10.1021/acsmedchemlett.1c00431
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.21 ug.mL-1 10.1016/j.bmcl.2018.11.002
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.25 ug.mL-1 10.1007/s00044-012-0101-3
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.25 ug.mL-1 10.1016/j.ejmech.2010.04.027
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.25 ug.mL-1 10.1016/j.ejmech.2019.07.057
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.25 ug.mL-1 10.1128/aac.00287-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.25 ug.mL-1 10.1128/aac.00749-08
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.25 ug.mL-1 10.1128/aac.01123-07
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.42 ug.mL-1 10.1016/j.bmcl.2018.11.002
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.46 ug.mL-1 10.1016/j.bmcl.2018.11.002
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.49 ug.mL-1 10.1016/j.bmcl.2018.11.002
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.5 ug.mL-1 10.1016/j.bmc.2012.12.011
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2014.03.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.5 ug.mL-1 10.1016/j.ejmech.2010.04.027
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.5 ug.mL-1 10.1016/j.ejmech.2019.07.057
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.5 ug.mL-1 10.1128/aac.00287-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.5 ug.mL-1 10.1128/aac.00414-06
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.5 ug.mL-1 10.1128/aac.01036-07
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.78 ug.mL-1 10.1016/j.bmc.2016.01.059
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.83 ug.mL-1 10.1016/j.ejmech.2011.04.025
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 0.94 ug.mL-1 10.1016/j.bmcl.2018.11.002
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1.0 ug.mL-1 10.1016/j.bmcl.2014.03.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1.0 ug.mL-1 10.1016/j.ejmech.2017.06.005
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1.0 ug.mL-1 10.1021/jm500432n
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1.0 ug.mL-1 10.1128/aac.00287-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1.0 ug.mL-1 10.1128/aac.00287-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1.0 ug.mL-1 10.1128/aac.00414-06
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1.0 ug.mL-1 10.1128/aac.00661-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1.0 ug.mL-1 10.1128/aac.01545-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2.0 ug.mL-1 10.1016/j.bmcl.2014.03.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2.0 ug.mL-1 10.1128/aac.00287-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2.0 ug.mL-1 10.1128/aac.00287-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2.0 ug.mL-1 10.1128/aac.00661-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 3.9 ug.mL-1 10.1016/j.bmcl.2018.05.049
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 4.0 ug.mL-1 10.1021/jm500432n
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 4.0 ug.mL-1 10.1128/aac.00287-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 4.0 ug.mL-1 10.1128/aac.00287-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 8.0 ug.mL-1 10.1128/aac.00287-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 8.0 ug.mL-1 10.1128/aac.00287-10
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 9.19 ug.mL-1 10.1016/j.ejmech.2018.01.080
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 10.26 ug.mL-1 10.1021/acsmedchemlett.1c00431
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 16.0 ug.mL-1 10.1016/j.bmcl.2018.11.002
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 33.2 ug.mL-1 10.1016/j.ejmech.2011.04.025
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 80.0 nM 10.1021/jm5005978
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 100.0 nM 10.1016/j.ejmech.2016.11.048
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 125.0 nM 10.1021/jm500571f
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 130.0 nM 10.1021/ml5001728
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 130.0 nM 10.1021/ml500531p
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 150.0 nM 10.1016/j.ejmech.2022.114206
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 150.0 nM 10.1021/jm5005978
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 156.0 nM 10.1016/j.bmcl.2014.03.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 160.0 nM 10.1021/jm5005978
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 170.0 nM 10.1021/acs.jmedchem.2c00266
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 240.0 nM 10.1016/j.bmc.2010.08.016
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 250.0 nM 10.1016/j.bmc.2010.08.016
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 250.0 nM 10.1021/ml5001728
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 250.0 nM 10.1021/ml500531p
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 290.0 nM 10.1016/j.bmcl.2009.12.062
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 290.0 nM 10.1016/j.bmcl.2011.02.008
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 300.0 nM 10.1016/j.bmc.2010.08.016
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 300.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 310.0 nM 10.1021/jm5005978
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 340.0 nM 10.1016/j.bmc.2010.08.016
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 400.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 420.0 nM 10.1021/acsmedchemlett.7b00356
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 450.0 nM 10.1016/j.ejmech.2016.11.048
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 470.0 nM 10.1016/j.ejmech.2011.03.010
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 500.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 500.0 nM 10.1016/j.ejmech.2012.01.007
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 500.0 nM 10.1039/C7MD00146K
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 500.0 nM 10.1128/aac.00055-06
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 700.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1100.0 nM 10.1016/j.ejmech.2021.114066
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1200.0 nM 10.1016/j.ejmech.2014.08.018
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1240.0 nM 10.1016/j.bmc.2016.07.051
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1240.0 nM 10.1016/j.ejmech.2014.12.046
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1260.0 nM 10.1016/j.bmc.2015.03.004
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1260.0 nM 10.1016/j.bmc.2016.01.011
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1260.0 nM 10.1016/j.bmc.2016.09.012
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1260.0 nM 10.1016/j.ejmech.2015.06.032
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 1400.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2000.0 nM 10.1021/ml5001728
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2000.0 nM 10.1021/ml500531p
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 2400.0 nM 10.1016/j.bmc.2015.11.039
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 4000.0 nM 10.1021/ml5001728
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 4000.0 nM 10.1021/ml500531p
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 8600.0 nM 10.1016/j.bmc.2014.06.041
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 10000.0 nM 10.1021/jm5005978
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 15900.0 nM 10.1128/aac.00055-06
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 31100.0 nM 10.1016/j.bmcl.2009.12.062
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 31100.0 nM 10.1016/j.bmcl.2011.02.008
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 128000.0 nM 10.1021/acsmedchemlett.7b00356
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC nan None 10.1016/j.bmcl.2018.05.049
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC50 0.038 ug.mL-1 10.1016/j.bmcl.2022.128824
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC50 0.038 ug.mL-1 10.1016/j.bmcl.2022.128871
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC50 0.25 ug.mL-1 10.1128/aac.01545-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC50 0.605 ug.mL-1 10.1016/j.bmcl.2022.128824
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC50 0.605 ug.mL-1 10.1016/j.bmcl.2022.128871
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC50 2.0 ug.mL-1 10.1128/aac.01545-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC50 41.0 nM 10.1021/acs.jmedchem.2c00266
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC50 120.0 nM 10.1021/acs.jmedchem.2c00266
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.031 ug.mL-1 10.1016/j.ejmech.2012.02.033
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.07 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.071 ug.mL-1 10.1016/j.bmcl.2022.128824
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.071 ug.mL-1 10.1016/j.bmcl.2022.128871
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.14 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.17 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.2 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.25 ug.mL-1 10.1128/aac.01545-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.27 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.39 ug.mL-1 10.1016/j.bmcl.2012.05.096
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 0.57 ug.mL-1 10.1016/j.ejmech.2022.114404
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 2.165 ug.mL-1 10.1016/j.bmcl.2022.128824
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 2.165 ug.mL-1 10.1016/j.bmcl.2022.128871
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 4.0 ug.mL-1 10.1128/aac.01545-09
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 15.93 ug.mL-1 10.1016/j.bmcl.2012.05.096
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 120.0 nM 10.1021/acs.jmedchem.7b01332
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 200.0 nM 10.1016/j.bmcl.2019.02.019
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 230.0 nM 10.1021/acs.jmedchem.7b01332
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 250.0 nM 10.1007/s00044-012-9971-7
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 260.0 nM 10.1021/acs.jmedchem.7b01332
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 350.0 nM 10.1021/acs.jmedchem.7b01332
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 360.0 nM 10.1021/acs.jmedchem.7b01332
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 460.0 nM 10.1021/jm201716n
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 460.0 nM 10.1021/jm900513a
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 640.0 nM 10.1016/j.bmcl.2011.08.054
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 770.0 nM 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 3080.0 nM 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 4300.0 nM 10.1016/j.bmcl.2011.08.054
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 6160.0 nM 10.1016/j.ejmech.2020.112821
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 8000.0 nM 10.1021/acs.jmedchem.7b01332
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 128000.0 nM 10.1021/jm900513a
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC99 0.07 uM 10.1021/acs.jmedchem.2c00266
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC99 0.19 uM 10.1021/acs.jmedchem.2c00266
Mycobacterium tuberculosis Mycobacterium tuberculosis Ratio 0.5 None 10.1021/jm500833f
Mycobacterium tuberculosis Mycobacterium tuberculosis Ratio 1.0 None 10.1021/jm500833f
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B CC25 2.0 uM 10.1128/aac.01380-07
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 2.0 ug.mL-1 10.1016/j.bmc.2012.12.011
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 5.5 ug.mL-1 10.1016/j.ejmech.2019.07.057
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 6000.0 nM 10.1128/aac.01380-07
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 8100.0 nM 10.1016/j.bmc.2014.06.041
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 10000.0 nM 10.1021/acs.jmedchem.2c00266
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 10000.0 nM 10.1021/ml5001933
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 11200.0 nM 10.1016/j.bmc.2015.03.004
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 11200.0 nM 10.1016/j.bmc.2015.11.039
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 11200.0 nM 10.1016/j.bmc.2016.01.011
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 11200.0 nM 10.1016/j.ejmech.2015.06.032
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 12500.0 nM 10.1021/jm500432n
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B IC50 12500.0 nM 10.1021/ml500531p
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) DNA gyrase subunit A/DNA gyrase subunit B Inhibition nan % 10.1021/jm500432n
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) Polyketide synthase Pks13 MIC=<90 0.0625 ug ml-1 10.1021/acs.jmedchem.9b00010
Mycobacterium tuberculosis variant bovis BCG Mycobacterium tuberculosis variant bovis BCG IC50 30.0 nM 10.1016/j.ejmech.2019.07.052
Mycobacterium tuberculosis variant bovis BCG Mycobacterium tuberculosis variant bovis BCG MIC 60.0 nM 10.1016/j.bmcl.2014.05.062
Mycobacterium ulcerans Mycobacterium ulcerans log10cfu 1.25 None 10.1128/aac.00730-07
Mycobacterium ulcerans Mycobacterium ulcerans log10cfu 1.72 None 10.1128/aac.00730-07
Mycobacterium ulcerans Mycobacterium ulcerans log10cfu 2.99 None 10.1128/aac.00730-07
Mycobacterium ulcerans Mycobacterium ulcerans log10cfu 3.23 None 10.1128/aac.00730-07
Mycobacterium ulcerans Mycobacterium ulcerans MIC 0.016 ug.mL-1 10.1128/aac.00400-10
Mycobacterium ulcerans Mycobacterium ulcerans MIC 0.03 ug.mL-1 10.1128/aac.00400-10
Mycobacterium ulcerans Mycobacterium ulcerans MIC 0.25 ug.mL-1 10.1128/aac.00400-10
Mycobacterium ulcerans Mycobacterium ulcerans MIC 0.25 ug.mL-1 10.1128/aac.00730-07
Mycobacterium ulcerans Mycobacterium ulcerans MIC 0.5 ug.mL-1 10.1128/aac.00400-10
Mycobacteroides abscessus Mycobacteroides abscessus MIC 16.0 ug.mL-1 10.1128/aac.01545-09
Mycobacteroides abscessus Mycobacteroides abscessus MIC 22400.0 nM 10.1016/j.bmcl.2014.05.062
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 64.0 ug.mL-1 10.1128/aac.01545-09
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 128.0 ug.mL-1 10.1128/aac.01545-09
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 2000.0 nM 10.1021/acsmedchemlett.1c00549
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 4000.0 nM 10.1021/acsmedchemlett.1c00549
Mycobacteroides chelonae Mycobacteroides chelonae MIC 8.0 ug.mL-1 10.1128/aac.01545-09
Mycobacteroides chelonae Mycobacteroides chelonae MIC 240.0 nM 10.1016/j.bmcl.2014.05.062
Mycobacteroides chelonae Mycobacteroides chelonae MIC50 32.0 ug.mL-1 10.1128/aac.01545-09
Mycobacteroides chelonae Mycobacteroides chelonae MIC90 32.0 ug.mL-1 10.1128/aac.01545-09
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC 0.06 ug.mL-1 10.1128/aac.01545-09
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC50 0.125 ug.mL-1 10.1128/aac.01545-09
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC90 0.25 ug.mL-1 10.1128/aac.01545-09
Mycolicibacterium phlei Mycolicibacterium phlei MIC 0.2 ug.mL-1 10.1016/j.ejmech.2010.04.027
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.03 ug.mL-1 10.1016/j.bmcl.2018.05.049
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.08 ug.mL-1 10.1016/j.bmcl.2011.05.112
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.1 ug.mL-1 10.1016/j.ejmech.2010.04.027
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.1 ug.mL-1 10.1016/j.ejmech.2018.11.032
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 700.0 nM 10.1021/np800751j
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae Activity nan None 10.1128/aac.00849-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.007 ug.mL-1 10.1128/aac.01684-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00746-09
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01684-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.063 ug.mL-1 10.1128/aac.00849-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.12 ug.mL-1 10.1021/jm301650g
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.25 ug.mL-1 10.1021/jm301650g
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01684-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00746-09
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC50 0.125 ug.mL-1 10.1128/aac.00849-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.01684-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC90 0.12 ug.mL-1 10.1128/aac.00746-09
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC90 0.125 ug.mL-1 10.1128/aac.00849-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.004 ug.mL-1 10.1016/j.bmcl.2021.128450
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.008 ug.mL-1 10.1016/j.bmcl.2021.128450
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.016 ug.mL-1 10.1016/j.bmcl.2021.128450
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.03 ug.mL-1 10.1016/j.bmcl.2021.128450
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2021.128450
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.5 ug.mL-1 10.1128/aac.01197-09
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 1.0 ug.mL-1 10.1128/aac.01197-09
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 2.0 ug.mL-1 10.1016/j.bmcl.2021.128450
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 2.0 ug.mL-1 10.1128/aac.01197-09
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2021.128450
Neisseria meningitidis Neisseria meningitidis Activity nan None 10.1128/aac.00418-09
Neisseria meningitidis Neisseria meningitidis MIC 0.004 ug.mL-1 10.1128/aac.00418-09
Neisseria meningitidis Neisseria meningitidis MIC50 0.008 ug.mL-1 10.1128/aac.00418-09
Neisseria meningitidis Neisseria meningitidis MIC90 0.008 ug.mL-1 10.1128/aac.00418-09
Nocardia brasiliensis Nocardia brasiliensis Activity nan None 10.1128/aac.00148-08
Nocardia brasiliensis Nocardia brasiliensis MIC 6e-05 ug.mL-1 10.1128/aac.01102-06
Nocardia brasiliensis Nocardia brasiliensis MIC 0.25 ug.mL-1 10.1128/aac.01023-08
Nocardia carnea Nocardia carnea MIC 6e-05 ug.mL-1 10.1128/aac.01102-06
Nocardia cyriacigeorgica Nocardia cyriacigeorgica MIC 6e-05 ug.mL-1 10.1128/aac.01102-06
Nocardia farcinica Nocardia farcinica MIC 6e-05 ug.mL-1 10.1128/aac.01102-06
Nocardia nova Nocardia nova MIC 0.002 ug.mL-1 10.1128/aac.01102-06
Nocardia otitidiscaviarum Nocardia otitidiscaviarum MIC 6e-05 ug.mL-1 10.1128/aac.01102-06
Nocardia sp. Nocardia sp. MIC 6e-05 ug.mL-1 10.1128/aac.01102-06
Nocardia transvalensis Nocardia transvalensis MIC 0.00012 ug.mL-1 10.1128/aac.01102-06
Oryctolagus cuniculus Oryctolagus cuniculus Activity 1.2 None 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus Activity 1.6 None 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus Activity 2.0 None 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus Activity 2.3 None 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus AUC 16500.0 ng.hr.mL-1 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus AUC 22200.0 ng.hr.mL-1 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus AUC 23900.0 ng.hr.mL-1 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus AUC 37500.0 ng.hr.mL-1 10.1128/aac.01520-06
Oryctolagus cuniculus Oryctolagus cuniculus Cmax 7099.44 nM 10.1128/aac.01520-06
Oryctolagus cuniculus Oryctolagus cuniculus Cmin 3.9 mg/L 10.1128/aac.01520-06
Oryctolagus cuniculus Oryctolagus cuniculus Drug uptake 0.23 mg/L 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus Drug uptake 0.51 mg/L 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus Drug uptake 1.0 mg/L 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus Drug uptake 3.33 mg/L 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus Drug uptake 3.73 mg/L 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus Drug uptake 4.39 mg/L 10.1128/aac.01376-06
Oryctolagus cuniculus Oryctolagus cuniculus T1/2 8.2 hr 10.1128/aac.01520-06
Parabacteroides distasonis Parabacteroides distasonis Activity 18.0 % 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis Activity 18.6 % 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis Activity 29.2 % 10.1128/aac.01435-06
Parabacteroides distasonis Parabacteroides distasonis Activity 53.3 % 10.1128/aac.00696-08
Parabacteroides distasonis Parabacteroides distasonis Activity 72.0 % 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis MIC 0.06 ug.mL-1 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis MIC 0.5 ug.mL-1 10.1128/aac.00696-08
Parabacteroides distasonis Parabacteroides distasonis MIC 2.32 ug.mL-1 10.1128/aac.01435-06
Parabacteroides distasonis Parabacteroides distasonis MIC50 1.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis MIC50 8.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides distasonis Parabacteroides distasonis MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides distasonis Parabacteroides distasonis MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Parabacteroides distasonis Parabacteroides distasonis MIC90 16.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides distasonis Parabacteroides distasonis MIC90 16.0 ug.mL-1 10.1128/aac.01435-06
Parabacteroides merdae Parabacteroides merdae Activity 28.3 % 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae Activity 36.4 % 10.1128/aac.01435-06
Parabacteroides merdae Parabacteroides merdae Activity 40.0 % 10.1128/aac.00696-08
Parabacteroides merdae Parabacteroides merdae MIC 0.25 ug.mL-1 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC 0.5 ug.mL-1 10.1128/aac.00696-08
Parabacteroides merdae Parabacteroides merdae MIC 3.85 ug.mL-1 10.1128/aac.01435-06
Parabacteroides merdae Parabacteroides merdae MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC50 2.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides merdae Parabacteroides merdae MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Parabacteroides merdae Parabacteroides merdae MIC90 16.0 ug.mL-1 10.1128/aac.00696-08
Parabacteroides merdae Parabacteroides merdae MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
Parvimonas micra Parvimonas micra Activity 8.0 % 10.1128/aac.00481-10
Parvimonas micra Parvimonas micra Activity 13.0 % 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra Activity 14.8 % 10.1128/aac.00696-08
Parvimonas micra Parvimonas micra Activity 78.0 % 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Parvimonas micra Parvimonas micra MIC 0.06 ug.mL-1 10.1128/aac.00696-08
Parvimonas micra Parvimonas micra MIC50 0.125 ug.mL-1 10.1128/aac.00481-10
Parvimonas micra Parvimonas micra MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra MIC50 0.5 ug.mL-1 10.1128/aac.00696-08
Parvimonas micra Parvimonas micra MIC90 0.25 ug.mL-1 10.1128/aac.00481-10
Parvimonas micra Parvimonas micra MIC90 8.0 ug.mL-1 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra MIC90 16.0 ug.mL-1 10.1128/aac.00696-08
Penicillium chrysogenum Penicillium chrysogenum MIC 1100.0 nM 10.1016/j.ejmech.2020.112513
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 0.0 % 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 13.0 % 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 14.8 % 10.1128/aac.00696-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 78.0 % 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity 100.0 % 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 0.06 ug.mL-1 10.1128/aac.00696-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 0.25 ug.mL-1 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 0.5 ug.mL-1 10.1128/aac.00696-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 2.0 ug.mL-1 10.1128/aac.00481-10
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 8.0 ug.mL-1 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 16.0 ug.mL-1 10.1128/aac.00696-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity 13.0 % 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity 78.0 % 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity 92.0 % 10.1128/aac.00481-10
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.125 ug.mL-1 10.1128/aac.00056-07
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.125 ug.mL-1 10.1128/aac.00481-10
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 0.125 ug.mL-1 10.1128/aac.00056-07
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 0.25 ug.mL-1 10.1128/aac.00481-10
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 8.0 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus sp. Peptostreptococcus sp. Activity 14.8 % 10.1128/aac.00696-08
Peptostreptococcus sp. Peptostreptococcus sp. Activity 98.1 % 10.1128/aac.00418-09
Peptostreptococcus sp. Peptostreptococcus sp. MIC 0.06 ug.mL-1 10.1128/aac.00696-08
Peptostreptococcus sp. Peptostreptococcus sp. MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Peptostreptococcus sp. Peptostreptococcus sp. MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Peptostreptococcus sp. Peptostreptococcus sp. MIC50 0.5 ug.mL-1 10.1128/aac.00696-08
Peptostreptococcus sp. Peptostreptococcus sp. MIC90 0.5 ug.mL-1 10.1128/aac.00418-09
Peptostreptococcus sp. Peptostreptococcus sp. MIC90 16.0 ug.mL-1 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 9.0 % 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 17.0 % 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 18.0 % 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus Activity 48.4 % 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 54.7 % 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 54.7 % 10.1128/aac.01435-06
Phocaeicola vulgatus Phocaeicola vulgatus Activity 72.0 % 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus Activity 91.0 % 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 0.13 ug.mL-1 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus MIC 0.25 ug.mL-1 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 0.25 ug.mL-1 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 0.5 ug.mL-1 10.1021/jm050035f
Phocaeicola vulgatus Phocaeicola vulgatus MIC 0.5 ug.mL-1 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 7.92 ug.mL-1 10.1128/aac.01435-06
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 8.0 ug.mL-1 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 2.0 ug.mL-1 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 16.0 ug.mL-1 10.1128/aac.00481-10
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 64.0 ug.mL-1 10.1128/aac.00696-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 64.0 ug.mL-1 10.1128/aac.01435-06
Plasmodium falciparum Plasmodium falciparum IC50 18.0 ug.mL-1 10.1016/j.ejmech.2018.01.039
Plasmodium falciparum Plasmodium falciparum IC50 44.8 ug.mL-1 10.1016/j.ejmech.2018.01.039
Plasmodium falciparum Plasmodium falciparum IC50 10000.0 nM 10.1021/acsmedchemlett.0c00196
Plasmodium falciparum Plasmodium falciparum IC50 10000.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 45000.0 nM 10.1016/j.bmcl.2004.03.070
Plasmodium yoelii yoelii Plasmodium yoelii yoelii IC50 100.0 ug.mL-1 10.1016/j.ejmech.2018.01.039
Plasmodium yoelii yoelii Plasmodium yoelii yoelii IC50 nan nM 10.1016/j.bmcl.2004.03.070
Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC 0.25 ug.mL-1 10.1128/aac.00481-10
Prevotella bivia Prevotella bivia Activity 11.0 % 10.1128/aac.00481-10
Prevotella bivia Prevotella bivia Activity 19.0 % 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia Activity 56.0 % 10.1128/aac.00481-10
Prevotella bivia Prevotella bivia Activity 75.0 % 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC 0.25 ug.mL-1 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC 0.5 ug.mL-1 10.1128/aac.00481-10
Prevotella bivia Prevotella bivia MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Prevotella bivia Prevotella bivia MIC90 8.0 ug.mL-1 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC90 8.0 ug.mL-1 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae Activity 11.0 % 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae Activity 19.0 % 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae Activity 56.0 % 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae Activity 75.0 % 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC 0.25 ug.mL-1 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC 0.5 ug.mL-1 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC50 2.0 ug.mL-1 10.1128/aac.00481-10
Prevotella buccae Prevotella buccae MIC90 8.0 ug.mL-1 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC90 8.0 ug.mL-1 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia Activity 0.0 % 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia Activity 19.0 % 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia Activity 75.0 % 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia Activity 100.0 % 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia MIC 0.25 ug.mL-1 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia MIC 0.5 ug.mL-1 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia MIC50 0.5 ug.mL-1 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia MIC90 0.5 ug.mL-1 10.1128/aac.00481-10
Prevotella intermedia Prevotella intermedia MIC90 8.0 ug.mL-1 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica Activity 19.0 % 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica Activity 75.0 % 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica MIC 0.25 ug.mL-1 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica MIC50 0.5 ug.mL-1 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica MIC90 8.0 ug.mL-1 10.1128/aac.00355-08
Priestia megaterium Priestia megaterium MIC 0.003 ug.mL-1 10.1016/j.bmc.2011.03.018
Propionibacterium Propionibacterium Activity 0.0 % 10.1128/aac.00696-08
Propionibacterium Propionibacterium MIC 0.25 ug.mL-1 10.1128/aac.00696-08
Propionibacterium Propionibacterium MIC50 0.25 ug.mL-1 10.1128/aac.00696-08
Propionibacterium Propionibacterium MIC90 0.5 ug.mL-1 10.1128/aac.00696-08
Proteus mirabilis Proteus mirabilis Activity 3.0 % 10.1128/aac.00078-09
Proteus mirabilis Proteus mirabilis Activity 30.3 % 10.1128/aac.00078-09
Proteus mirabilis Proteus mirabilis Activity 62.0 % 10.1128/aac.00418-09
Proteus mirabilis Proteus mirabilis Activity 63.6 % 10.1128/aac.00078-09
Proteus mirabilis Proteus mirabilis Activity 78.8 % 10.1128/aac.00078-09
Proteus mirabilis Proteus mirabilis Activity 81.8 % 10.1128/aac.00078-09
Proteus mirabilis Proteus mirabilis Activity 84.8 % 10.1128/aac.00078-09
Proteus mirabilis Proteus mirabilis Activity 100.0 % 10.1128/aac.00078-09
Proteus mirabilis Proteus mirabilis MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Proteus mirabilis Proteus mirabilis MIC 0.25 ug.mL-1 10.1128/aac.01197-09
Proteus mirabilis Proteus mirabilis MIC 0.25 ug.mL-1 10.1128/aac.01374-09
Proteus mirabilis Proteus mirabilis MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Proteus mirabilis Proteus mirabilis MIC50 0.5 ug.mL-1 10.1128/aac.01374-09
Proteus mirabilis Proteus mirabilis MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Proteus mirabilis Proteus mirabilis MIC90 0.5 ug.mL-1 10.1128/aac.01374-09
Proteus mirabilis Proteus mirabilis MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Proteus mirabilis Proteus mirabilis MIC90 16.0 ug.mL-1 10.1128/aac.00418-09
Proteus vulgaris Proteus vulgaris Activity 100.0 % 10.1128/aac.00418-09
Proteus vulgaris Proteus vulgaris MBC 0.008 ug ml-1 10.1016/j.ejmech.2019.06.071
Proteus vulgaris Proteus vulgaris MIC 0.004 ug.mL-1 10.1016/j.ejmech.2019.06.071
Proteus vulgaris Proteus vulgaris MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Proteus vulgaris Proteus vulgaris MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Proteus vulgaris Proteus vulgaris MIC90 0.5 ug.mL-1 10.1128/aac.00418-09
Providencia stuartii Providencia stuartii MIC 8.0 ug.mL-1 10.1128/aac.01374-09
Providencia stuartii Providencia stuartii MIC50 32.0 ug.mL-1 10.1128/aac.01374-09
Providencia stuartii Providencia stuartii MIC90 64.0 ug.mL-1 10.1128/aac.01374-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 1.5 % 10.1128/aac.00078-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 2.9 % 10.1128/aac.00078-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 5.8 % 10.1128/aac.00078-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 23.4 % 10.1128/aac.00078-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 51.1 % 10.1128/aac.00078-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 64.2 % 10.1128/aac.00078-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 76.6 % 10.1128/aac.00078-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 100.0 % 10.1128/aac.00078-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Log 1/C 5.64 None 10.1021/jm030986y
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 16.0 ug ml-1 10.1016/j.ejmech.2019.06.071
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.0078 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.2 ug.mL-1 10.1021/jm020328y
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1016/j.ejmech.2011.03.026
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1016/j.bmcl.2018.03.037
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1016/j.ejmech.2011.10.048
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.01374-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.7 ug.mL-1 10.1016/j.bmc.2010.06.098
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.7 ug.mL-1 10.1016/j.bmc.2011.03.018
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.78 ug.mL-1 10.1016/j.bmc.2009.08.026
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.78 ug.mL-1 10.1021/acs.jmedchem.8b00644
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.78 ug.mL-1 10.1021/jm301650g
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2005.11.064
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.04.081
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.10.028
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2016.11.001
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.bmcl.2021.128450
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.ejmech.2013.12.054
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1016/j.ejmech.2019.03.059
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1128/aac.01197-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.04.081
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.10.028
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.ejmech.2011.03.026
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.ejmech.2013.12.054
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1016/j.bmcl.2015.07.044
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1021/jm050035f
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1016/j.bmcl.2021.128450
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1039/c9md00051h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.bmcl.2021.128450
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.ejmech.2019.06.071
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1039/c9md00051h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 100.0 ug.mL-1 10.1016/j.bmc.2010.06.098
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2490.0 nM 10.1016/j.ejmech.2019.01.038
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4990.0 nM 10.1016/j.ejmech.2019.01.038
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 9980.0 nM 10.1016/j.ejmech.2019.01.038
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 71500.0 nM 10.1016/j.ejmech.2020.112513
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 2.0 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 2.0 ug.mL-1 10.1128/aac.01374-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 8.0 ug.mL-1 10.1128/aac.01197-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 64.0 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 3.9 ug.mL-1 10.1016/j.bmcl.2017.01.073
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 4.0 ug.mL-1 10.1128/aac.01374-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 8.0 ug.mL-1 10.1039/C9MD00120D
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 8.0 ug.mL-1 10.1128/aac.00078-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 128.0 ug.mL-1 10.1128/aac.00418-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio 16.0 None 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa Survival 7.0 % 10.1021/acs.jmedchem.6b00867
Pseudomonas aeruginosa Pseudomonas aeruginosa Survival 27.0 % 10.1021/acs.jmedchem.6b00867
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Hepatocyte CC50 100000.0 nM 10.1021/jm060844e
Rattus norvegicus L6 IC50 5778.3 nM 10.1016/j.ejmech.2020.112513
Rattus norvegicus Plasma Fu 0.6 None 10.1021/jm901371v
Rattus norvegicus Rattus norvegicus AUC 4460.0 ng.hr.mL-1 10.1021/acs.jmedchem.8b00644
Rattus norvegicus Rattus norvegicus Cmax 3711.64 nM 10.1021/acs.jmedchem.8b00644
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 100.0 ug.mL-1 10.1016/j.bmc.2011.03.018
Salmonella enterica Salmonella enterica MIC 4300.0 nM 10.1016/j.ejmech.2020.112513
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.061 ug.mL-1 10.1016/j.bmcl.2005.11.064
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.5 ug.mL-1 10.1016/j.bmcl.2015.04.081
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.5 ug.mL-1 10.1016/j.bmcl.2015.10.028
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.5 ug.mL-1 10.1016/j.ejmech.2013.12.054
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.5 ug.mL-1 10.1128/aac.00294-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 1.0 ug.mL-1 10.1016/j.bmcl.2016.11.001
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 1.0 ug.mL-1 10.1016/j.ejmech.2013.12.054
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 2.0 ug.mL-1 10.1128/aac.00121-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC nan None 10.1128/aac.00121-09
Schaalia meyeri Schaalia meyeri Activity 0.0 % 10.1128/aac.00481-10
Schaalia meyeri Schaalia meyeri Activity 92.0 % 10.1128/aac.00481-10
Schaalia meyeri Schaalia meyeri MIC 0.06 ug.mL-1 10.1128/aac.00481-10
Schaalia meyeri Schaalia meyeri MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
Schaalia meyeri Schaalia meyeri MIC90 2.0 ug.mL-1 10.1128/aac.00481-10
Serratia marcescens Serratia marcescens Activity 98.0 % 10.1128/aac.00418-09
Serratia marcescens Serratia marcescens MBC 0.5 ug ml-1 10.1016/j.ejmech.2019.06.071
Serratia marcescens Serratia marcescens MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Serratia marcescens Serratia marcescens MIC 0.06 ug.mL-1 10.1128/aac.01374-09
Serratia marcescens Serratia marcescens MIC 0.25 ug.mL-1 10.1016/j.ejmech.2019.06.071
Serratia marcescens Serratia marcescens MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Serratia marcescens Serratia marcescens MIC50 0.5 ug.mL-1 10.1128/aac.01374-09
Serratia marcescens Serratia marcescens MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Serratia marcescens Serratia marcescens MIC90 1.0 ug.mL-1 10.1128/aac.01374-09
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 29.02 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.09676 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -0.07 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition index 0.8056 None 10.1101/2020.04.03.023846
Stachybotrys chartarum Stachybotrys chartarum MIC 2300.0 nM 10.1016/j.ejmech.2020.112513
Staphylococcus Staphylococcus Activity 55.0 % 10.1128/aac.00845-09
Staphylococcus Staphylococcus MIC 0.03 ug.mL-1 10.1128/aac.00723-10
Staphylococcus Staphylococcus MIC 0.03 ug.mL-1 10.1128/aac.01197-09
Staphylococcus Staphylococcus MIC 0.06 ug.mL-1 10.1128/aac.00723-10
Staphylococcus Staphylococcus MIC 0.12 ug.mL-1 10.1128/aac.00845-09
Staphylococcus Staphylococcus MIC50 0.12 ug.mL-1 10.1128/aac.01197-09
Staphylococcus Staphylococcus MIC50 0.125 ug.mL-1 10.1128/aac.00723-10
Staphylococcus Staphylococcus MIC50 0.25 ug.mL-1 10.1128/aac.00845-09
Staphylococcus Staphylococcus MIC50 2.0 ug.mL-1 10.1128/aac.00723-10
Staphylococcus Staphylococcus MIC90 2.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus Staphylococcus MIC90 4.0 ug.mL-1 10.1128/aac.00723-10
Staphylococcus Staphylococcus MIC90 8.0 ug.mL-1 10.1128/aac.00723-10
Staphylococcus Staphylococcus MIC90 8.0 ug.mL-1 10.1128/aac.00845-09
Staphylococcus aureus DNA gyrase IC50 4.38 ug.mL-1 10.1016/j.bmc.2009.08.026
Staphylococcus aureus DNA gyrase IC50 6800.0 nM 10.1021/acs.jmedchem.2c00266
Staphylococcus aureus DNA gyrase IC50 7700.0 nM 10.1021/jm101604v
Staphylococcus aureus DNA gyrase IC50 18000.0 nM 10.1021/jm2002124
Staphylococcus aureus DNA gyrase IC50 27500.0 nM 10.1128/aac.00158-07
Staphylococcus aureus DNA gyrase IC50 28000.0 nM 10.1021/jm060844e
Staphylococcus aureus DNA gyrase subunit A IC50 512.0 ug.mL-1 10.1016/j.bmc.2009.08.026
Staphylococcus aureus DNA gyrase subunit A IC50 200000.0 nM 10.1021/jm101604v
Staphylococcus aureus DNA gyrase subunit A IC50 227000.0 nM 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus Activity 0.0 % 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus Activity 0.7 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 3.0 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 3.7 log10CFU 10.1021/acs.jmedchem.7b01634
Staphylococcus aureus Staphylococcus aureus Activity 3.7 log10CFU 10.1021/acs.jmedchem.9b01846
Staphylococcus aureus Staphylococcus aureus Activity 4.0 % 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus Activity 5.8 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 6.3 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 6.4 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 6.9 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 7.1 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 7.1 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 8.0 % 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus Activity 9.1 % 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus Activity 9.4 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 14.3 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 15.0 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 20.0 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 20.4 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 21.3 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 26.0 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 32.0 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 39.4 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 51.2 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 53.7 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 61.2 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 67.0 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 87.7 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 88.9 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 89.8 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 90.1 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 91.4 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 91.5 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 91.7 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 92.0 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 92.0 % 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus Activity 93.0 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 93.9 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 96.1 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 98.4 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 99.9 % 10.1021/acs.jmedchem.6b00485
Staphylococcus aureus Staphylococcus aureus Activity 100.0 % 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus Activity 100.0 % 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus Activity 100.0 % 10.1128/aac.01538-07
Staphylococcus aureus Staphylococcus aureus Activity 124.2 um 10.1021/acs.jmedchem.7b01634
Staphylococcus aureus Staphylococcus aureus Activity 140.3 um 10.1021/acs.jmedchem.7b01634
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.bmc.2008.09.010
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.bmc.2019.115151
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/acs.jmedchem.7b01634
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/jm801007z
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus AUC 44150.0 ng.hr.mL-1 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus deltalog10CFU 4.34 None 10.1128/aac.01520-06
Staphylococcus aureus Staphylococcus aureus deltalog10CFU 4.47 None 10.1128/aac.01520-06
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 0.0 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 0.9 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 1.0 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 1.5 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 1.7 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 2.0 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 2.3 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 2.4 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 2.6 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 2.7 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 3.1 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 3.2 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus deltalog10CFU/ml 3.4 None 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus fAUC/MIC 16.0 None 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus fAUC/MIC 24.0 None 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus fAUC/MIC 31.0 None 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus fAUC/MIC 32.0 None 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus fAUC/MIC 63.0 None 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus fAUC/MIC 114.0 None 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus fAUC/MIC 236.0 None 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus fAUC/MIC 449.0 None 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus fCmax 2.52 ug ml-1 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus FRE 2.1e-06 None 10.1021/jm050035f
Staphylococcus aureus Staphylococcus aureus FRE 3.1e-05 None 10.1021/jm050035f
Staphylococcus aureus Staphylococcus aureus FRE 4.51e-05 None 10.1021/jm050035f
Staphylococcus aureus Staphylococcus aureus IC50 7500.0 nM 10.1021/np100135b
Staphylococcus aureus Staphylococcus aureus IZ 31.0 mm 10.1128/aac.01306-05
Staphylococcus aureus Staphylococcus aureus log10cfu -1.32 None 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus log10cfu 1.0 None 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus log10cfu 1.33 None 10.1128/aac.00237-08
Staphylococcus aureus Staphylococcus aureus log10cfu 2.1 None 10.1128/aac.00237-08
Staphylococcus aureus Staphylococcus aureus log10cfu 2.49 None 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus log10cfu 3.0 None 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus log10CFU/g 2.1 None 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus log10CFU/g 2.2 None 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus log10CFU/ml -4.5 None 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus log10CFU/ml 2.33 None 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus log10CFU/ml 2.38 None 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus log10CFU/ml 2.76 mg/L 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus log10CFU/ml 2.83 None 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus log10CFU/ml 3.0 None 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus log10CFU/ml 3.01 None 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus log10CFU/ml 4.04 None 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus log10CFU/ml 4.06 None 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus Log 1/C 7.16 None 10.1021/jm030986y
Staphylococcus aureus Staphylococcus aureus MBC 0.063 ug ml-1 10.1016/j.ejmech.2019.06.071
Staphylococcus aureus Staphylococcus aureus MBC 0.125 mg/L 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus MBC 0.125 ug ml-1 10.1016/j.ejmech.2019.06.071
Staphylococcus aureus Staphylococcus aureus MBC 0.25 ug ml-1 10.1016/j.bmcl.2015.04.081
Staphylococcus aureus Staphylococcus aureus MBC 0.25 ug ml-1 10.1016/j.ejmech.2019.06.071
Staphylococcus aureus Staphylococcus aureus MBC 1.0 ug ml-1 10.1016/j.bmcl.2015.04.081
Staphylococcus aureus Staphylococcus aureus MBC 2.0 ug ml-1 10.1016/j.bmcl.2015.04.081
Staphylococcus aureus Staphylococcus aureus MBC 4.0 ug ml-1 10.1016/j.bmcl.2015.04.081
Staphylococcus aureus Staphylococcus aureus MBIC 0.5 ug ml-1 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus MBIC nan None 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus MIC 0.008 ug.mL-1 10.1016/j.bmcl.2015.10.027
Staphylococcus aureus Staphylococcus aureus MIC 0.008 ug.mL-1 10.1016/j.bmcl.2016.03.050
Staphylococcus aureus Staphylococcus aureus MIC 0.008 ug.mL-1 10.1016/j.ejmech.2011.10.048
Staphylococcus aureus Staphylococcus aureus MIC 0.008 ug.mL-1 10.1016/j.ejmech.2014.09.029
Staphylococcus aureus Staphylococcus aureus MIC 0.013 ug.mL-1 10.1016/j.bmc.2009.08.026
Staphylococcus aureus Staphylococcus aureus MIC 0.013 ug.mL-1 10.1021/jm020328y
Staphylococcus aureus Staphylococcus aureus MIC 0.015 ug.mL-1 10.1016/j.ejmech.2014.09.029
Staphylococcus aureus Staphylococcus aureus MIC 0.015 ug.mL-1 10.1021/acs.jmedchem.8b00644
Staphylococcus aureus Staphylococcus aureus MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC 0.015 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC 0.015 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC 0.016 ug.mL-1 10.1016/j.bmcl.2021.128484
Staphylococcus aureus Staphylococcus aureus MIC 0.02 ug.mL-1 10.1016/j.bmcl.2004.07.064
Staphylococcus aureus Staphylococcus aureus MIC 0.025 ug.mL-1 10.1021/acs.jmedchem.8b00644
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1016/j.bmc.2008.09.010
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1016/j.bmc.2010.06.098
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1016/j.bmc.2011.03.018
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1016/j.ejmech.2011.10.048
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1021/jm801007z
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC 0.032 ug.mL-1 10.1128/aac.01520-06
Staphylococcus aureus Staphylococcus aureus MIC 0.04 ug.mL-1 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus MIC 0.05 ug.mL-1 10.1016/j.bmcl.2022.128665
Staphylococcus aureus Staphylococcus aureus MIC 0.05 ug.mL-1 10.1021/jm301650g
Staphylococcus aureus Staphylococcus aureus MIC 0.05 ug.mL-1 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2005.11.065
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2012.05.063
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2015.10.027
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2016.03.050
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2017.10.006
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2021.128450
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.ejmech.2018.08.061
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.ejmech.2020.113134
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/acs.jmedchem.1c00375
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/acsmedchemlett.5b00368
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/jm050035f
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/jm060844e
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/jm101604v
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/jm2002124
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1128/aac.01315-06
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC 0.061 ug.mL-1 10.1016/j.bmcl.2005.11.064
Staphylococcus aureus Staphylococcus aureus MIC 0.0625 ug.mL-1 10.1016/j.bmcl.2015.07.044
Staphylococcus aureus Staphylococcus aureus MIC 0.0625 ug.mL-1 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.06.071
Staphylococcus aureus Staphylococcus aureus MIC 0.064 ug.mL-1 10.1128/aac.00274-07
Staphylococcus aureus Staphylococcus aureus MIC 0.064 ug.mL-1 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus MIC 0.08 ug.mL-1 10.1021/jm1003304
Staphylococcus aureus Staphylococcus aureus MIC 0.09 ug.mL-1 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2011.03.026
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2019.06.071
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus MIC 0.19 ug.mL-1 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2013.05.082
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2015.04.081
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2015.10.028
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2016.11.001
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2018.03.037
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2019.02.033
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2011.03.026
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2013.12.054
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2019.03.059
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/jm1003304
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00274-07
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.01520-06
Staphylococcus aureus Staphylococcus aureus MIC 0.31 ug.mL-1 10.1021/jm1003304
Staphylococcus aureus Staphylococcus aureus MIC 0.38 ug.mL-1 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2021.128450
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.00959-06
Staphylococcus aureus Staphylococcus aureus MIC 0.6 ug.mL-1 10.1016/j.ejmech.2021.113741
Staphylococcus aureus Staphylococcus aureus MIC 0.7 ug.mL-1 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus MIC 0.75 ug.mL-1 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus MIC 0.78 ug.mL-1 10.1016/j.bmcl.2004.07.064
Staphylococcus aureus Staphylococcus aureus MIC 0.78 ug.mL-1 10.1021/acs.jmedchem.8b00644
Staphylococcus aureus Staphylococcus aureus MIC 0.78 ug.mL-1 10.1021/jm301650g
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2013.05.082
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.04.081
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.10.028
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2018.03.037
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2019.02.033
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2021.128450
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2021.128484
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2013.12.054
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2019.03.059
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2020.113134
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/jm2002124
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.01520-06
Staphylococcus aureus Staphylococcus aureus MIC 1.5 ug.mL-1 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus MIC 1.56 ug.mL-1 10.1021/acs.jmedchem.8b00644
Staphylococcus aureus Staphylococcus aureus MIC 1.56 ug.mL-1 10.1021/acs.jnatprod.5b00975
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2005.11.064
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2005.11.065
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2013.05.082
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.04.081
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.07.044
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.10.028
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2016.11.001
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2013.12.054
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2019.03.059
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm050035f
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm060844e
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm1003304
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm101604v
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00237-08
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01145-08
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC 2.5 ug.mL-1 10.1021/jm1003304
Staphylococcus aureus Staphylococcus aureus MIC 3.12 ug.mL-1 10.1016/j.bmcl.2022.128665
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2013.05.082
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2015.04.081
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2015.07.044
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2015.10.028
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2018.03.037
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2019.02.033
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.ejmech.2013.12.054
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.ejmech.2019.03.059
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.1c00375
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm050035f
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm060844e
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm101604v
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm2002124
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00646-06
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.01315-06
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC 5.0 ug.mL-1 10.1021/jm1003304
Staphylococcus aureus Staphylococcus aureus MIC 5.25 ug.mL-1 10.1016/j.bmcl.2022.128665
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.ejmech.2020.112686
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1021/jm2002124
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC 12.0 ug.mL-1 10.1016/j.bmc.2010.06.098
Staphylococcus aureus Staphylococcus aureus MIC 12.0 ug.mL-1 10.1016/j.bmc.2011.03.018
Staphylococcus aureus Staphylococcus aureus MIC 12.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1016/j.bmcl.2022.128665
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1021/jm2002124
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1128/aac.01315-06
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC 50.0 ug.mL-1 10.1016/j.bmc.2010.06.098
Staphylococcus aureus Staphylococcus aureus MIC 50.0 ug.mL-1 10.1016/j.bmc.2011.03.018
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/jm2002124
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00158-07
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.01315-06
Staphylococcus aureus Staphylococcus aureus MIC 140.0 nM 10.1021/acs.jmedchem.2c00266
Staphylococcus aureus Staphylococcus aureus MIC 310.0 nM 10.1016/j.ejmech.2017.10.045
Staphylococcus aureus Staphylococcus aureus MIC 310.0 nM 10.1016/j.ejmech.2019.01.038
Staphylococcus aureus Staphylococcus aureus MIC 500.0 nM 10.1016/j.ejmech.2020.112513
Staphylococcus aureus Staphylococcus aureus MIC 620.0 nM 10.1016/j.ejmech.2017.10.045
Staphylococcus aureus Staphylococcus aureus MIC 620.0 nM 10.1016/j.ejmech.2019.01.038
Staphylococcus aureus Staphylococcus aureus MIC 900.0 nM 10.1021/acs.jnatprod.6b00809
Staphylococcus aureus Staphylococcus aureus MIC 1250.0 nM 10.1016/j.ejmech.2019.01.038
Staphylococcus aureus Staphylococcus aureus MIC 3800.0 nM 10.1021/acs.jnatprod.6b00809
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1016/j.ejmech.2017.10.045
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1021/acsmedchemlett.5b00266
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1128/aac.00455-10
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1128/aac.01315-06
Staphylococcus aureus Staphylococcus aureus MIC50 0.03 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC50 0.06 ug.mL-1 10.1021/acs.jmedchem.8b00644
Staphylococcus aureus Staphylococcus aureus MIC50 0.06 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC50 0.06 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC50 0.06 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC50 0.12 ug.mL-1 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus MIC50 0.125 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC50 0.25 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC50 2.0 ug.mL-1 10.1016/j.bmc.2009.08.026
Staphylococcus aureus Staphylococcus aureus MIC50 2.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1016/j.bmc.2009.08.026
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1016/j.bmcl.2017.10.006
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1021/jm020328y
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.00078-09
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC80 32.0 ug.mL-1 10.1016/j.bmc.2009.08.026
Staphylococcus aureus Staphylococcus aureus MIC90 0.06 ug.mL-1 10.1039/C9MD00120D
Staphylococcus aureus Staphylococcus aureus MIC90 0.06 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC90 0.06 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC90 0.12 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC90 0.12 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC90 0.125 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC90 0.125 ug.mL-1 10.1128/aac.01056-08
Staphylococcus aureus Staphylococcus aureus MIC90 0.25 ug.mL-1 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus MIC90 1.95 ug.mL-1 10.1016/j.bmcl.2017.01.073
Staphylococcus aureus Staphylococcus aureus MIC90 2.0 ug.mL-1 10.1021/acs.jmedchem.8b00644
Staphylococcus aureus Staphylococcus aureus MIC90 2.0 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.00845-09
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus aureus Staphylococcus aureus MIC90 16.0 ug.mL-1 10.1021/jm020328y
Staphylococcus aureus Staphylococcus aureus MIC90 16.0 ug.mL-1 10.1128/aac.01150-08
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1016/j.bmc.2009.08.026
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1016/j.bmcl.2017.10.006
Staphylococcus aureus Staphylococcus aureus MIC90 64.0 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC90 200.0 nM 10.1021/acsmedchemlett.1c00549
Staphylococcus aureus Staphylococcus aureus MPC 10.0 ug ml-1 10.1021/jm050035f
Staphylococcus aureus Staphylococcus aureus MPC/MIC 5.0 None 10.1021/jm050035f
Staphylococcus aureus Staphylococcus aureus PD50 nan None 10.1021/acsmedchemlett.5b00266
Staphylococcus aureus Staphylococcus aureus Post anitbiotic effect 1.5 hr 10.1128/aac.01315-06
Staphylococcus aureus Staphylococcus aureus Post anitbiotic effect 1.6 hr 10.1128/aac.01315-06
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 8.7 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 12.0 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 15.1 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 16.6 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 18.6 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 19.1 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 19.5 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 20.4 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 20.9 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 21.4 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 22.4 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 23.4 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 25.1 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 25.4 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 26.3 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 30.2 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 30.9 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 41.7 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 42.7 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 43.7 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 45.7 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 49.0 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 52.7 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 53.7 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 56.2 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 61.7 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 64.6 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 67.6 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 70.8 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 83.2 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 85.1 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 89.1 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 95.5 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus RatioAUC/MIC 120.0 None 10.1128/aac.00118-09
Staphylococcus aureus Staphylococcus aureus Survival 15.3 day 10.1128/aac.01376-06
Staphylococcus aureus Staphylococcus aureus T1/2 12.13 hr 10.1128/aac.00455-10
Staphylococcus aureus Topoisomerase IV subunit A IC50 800.0 nM 10.1016/j.bmcl.2005.11.064
Staphylococcus aureus Topoisomerase IV subunit A IC50 800.0 nM 10.1016/j.bmcl.2005.11.065
Staphylococcus epidermidis Staphylococcus epidermidis Activity 0.0 % 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 11.1 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 30.2 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 33.3 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 34.6 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 41.7 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 50.0 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 53.5 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 55.8 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 62.8 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 74.4 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 80.0 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 83.3 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 90.7 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 93.0 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 96.0 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 100.0 % 10.1128/aac.00078-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 100.0 % 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 100.0 % 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity nan None 10.1128/aac.01538-07
Staphylococcus epidermidis Staphylococcus epidermidis log10cfu -0.41 None 10.1128/aac.00237-08
Staphylococcus epidermidis Staphylococcus epidermidis log10cfu 2.5 None 10.1128/aac.00237-08
Staphylococcus epidermidis Staphylococcus epidermidis MBC 0.032 ug ml-1 10.1016/j.ejmech.2019.06.071
Staphylococcus epidermidis Staphylococcus epidermidis MBC 0.125 ug ml-1 10.1016/j.ejmech.2019.06.071
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.016 ug.mL-1 10.1016/j.bmcl.2015.07.044
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.03 ug.mL-1 10.1016/j.ejmech.2014.09.029
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.03 ug.mL-1 10.1128/aac.01197-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.03 ug.mL-1 10.1128/aac.01374-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.032 ug.mL-1 10.1016/j.ejmech.2019.06.071
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.06.071
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.07 ug.mL-1 10.1016/j.bmc.2010.06.098
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.07 ug.mL-1 10.1016/j.bmc.2011.03.018
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.1 ug.mL-1 10.1016/j.bmc.2009.08.026
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.1 ug.mL-1 10.1016/j.bmcl.2004.07.064
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.1 ug.mL-1 10.1021/jm020328y
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.1 ug.mL-1 10.1021/jm301650g
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.125 ug.mL-1 10.1016/j.ejmech.2011.03.026
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.125 ug.mL-1 10.1016/j.ejmech.2014.09.029
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.125 ug.mL-1 10.1128/aac.00237-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.25 ug.mL-1 10.1016/j.ejmech.2011.03.026
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.25 ug.mL-1 10.1016/j.ejmech.2014.09.029
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.5 ug.mL-1 10.1016/j.ejmech.2011.10.048
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.5 ug.mL-1 10.1128/aac.01374-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.07.044
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Staphylococcus epidermidis Staphylococcus epidermidis MIC 8.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Staphylococcus epidermidis Staphylococcus epidermidis MIC 8.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Staphylococcus epidermidis Staphylococcus epidermidis MIC 16.0 ug.mL-1 10.1016/j.ejmech.2011.10.048
Staphylococcus epidermidis Staphylococcus epidermidis MIC 16.0 ug.mL-1 10.1016/j.ejmech.2014.09.029
Staphylococcus epidermidis Staphylococcus epidermidis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2015.10.027
Staphylococcus epidermidis Staphylococcus epidermidis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2016.03.050
Staphylococcus epidermidis Staphylococcus epidermidis MIC 50.0 ug.mL-1 10.1016/j.bmc.2010.06.098
Staphylococcus epidermidis Staphylococcus epidermidis MIC 50.0 ug.mL-1 10.1016/j.bmc.2011.03.018
Staphylococcus epidermidis Staphylococcus epidermidis MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 0.06 ug.mL-1 10.1128/aac.01374-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 0.12 ug.mL-1 10.1128/aac.01197-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 0.25 ug.mL-1 10.1016/j.ejmech.2012.07.010
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 2.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 2.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 0.12 ug.mL-1 10.1128/aac.01374-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 2.0 ug.mL-1 10.1128/aac.01197-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 4.0 ug.mL-1 10.1128/aac.01374-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 8.0 ug.mL-1 10.1016/j.ejmech.2012.07.010
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 nan None 10.1128/aac.00418-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 39.6 % 10.1128/aac.00418-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 0.06 ug.mL-1 10.1021/jm050035f
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC50 1.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus hominis Staphylococcus hominis Activity 34.0 % 10.1128/aac.00418-09
Staphylococcus hominis Staphylococcus hominis MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Staphylococcus hominis Staphylococcus hominis MIC50 1.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus hominis Staphylococcus hominis MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus lugdunensis Staphylococcus lugdunensis Activity 27.0 % 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis Activity 33.0 % 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis Activity 40.0 % 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis Activity 73.3 % 10.1128/aac.00418-09
Staphylococcus lugdunensis Staphylococcus lugdunensis BBC 0.125 ug ml-1 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis BBC 0.25 ug ml-1 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis BBC 0.5 ug ml-1 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis BBC 1.0 ug ml-1 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis BBC 2.0 ug ml-1 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis MBC50 0.125 ug ml-1 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis MBC90 0.25 ug ml-1 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC50 0.125 ug.mL-1 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC90 0.25 ug.mL-1 10.1128/aac.01052-06
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC90 2.0 ug.mL-1 10.1128/aac.00418-09
Staphylococcus saprophyticus Staphylococcus saprophyticus Activity 100.0 % 10.1128/aac.00418-09
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 0.25 ug.mL-1 10.1021/jm050035f
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC90 0.12 ug.mL-1 10.1128/aac.00418-09
Staphylococcus warneri Staphylococcus warneri Activity 76.0 % 10.1128/aac.00418-09
Staphylococcus warneri Staphylococcus warneri MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Staphylococcus warneri Staphylococcus warneri MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Staphylococcus warneri Staphylococcus warneri MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 7.7 % 10.1128/aac.00078-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 15.4 % 10.1128/aac.00078-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 42.3 % 10.1128/aac.00078-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 65.4 % 10.1128/aac.00078-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 76.9 % 10.1128/aac.00078-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 92.3 % 10.1128/aac.00078-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 100.0 % 10.1128/aac.00078-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity nan None 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 0.031 ug.mL-1 10.1016/j.bmcl.2005.11.064
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 0.064 ug.mL-1 10.1128/aac.00496-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 0.19 ug.mL-1 10.1128/aac.00496-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 0.75 ug.mL-1 10.1128/aac.00496-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.6b00867
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 0.5 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 8.0 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae Activity nan None 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC 0.12 ug.mL-1 10.1021/jm050035f
Streptococcus agalactiae Streptococcus agalactiae MIC 0.12 ug.mL-1 10.1128/aac.01197-09
Streptococcus agalactiae Streptococcus agalactiae MIC 0.12 ug.mL-1 10.1128/aac.01374-09
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.25 ug.mL-1 10.1128/aac.01197-09
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.25 ug.mL-1 10.1128/aac.01374-09
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.25 ug.mL-1 10.1128/aac.01374-09
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.5 ug.mL-1 10.1128/aac.01197-09
Streptococcus constellatus Streptococcus constellatus Activity nan None 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus Activity nan None 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius Activity nan None 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis Activity nan None 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis MIC 0.1 ug.mL-1 10.1016/j.bmc.2009.08.026
Streptococcus mitis Streptococcus mitis MIC 0.1 ug.mL-1 10.1016/j.bmcl.2004.07.064
Streptococcus mitis Streptococcus mitis MIC 0.1 ug.mL-1 10.1021/jm020328y
Streptococcus mitis Streptococcus mitis MIC 0.12 ug.mL-1 10.1128/aac.00845-09
Streptococcus mitis Streptococcus mitis MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis MIC50 0.25 ug.mL-1 10.1128/aac.00845-09
Streptococcus mitis Streptococcus mitis MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Streptococcus mutans Streptococcus mutans MBC 0.25 ug ml-1 10.1016/j.bmcl.2015.04.081
Streptococcus mutans Streptococcus mutans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2015.04.081
Streptococcus mutans Streptococcus mutans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2015.10.028
Streptococcus mutans Streptococcus mutans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2016.11.001
Streptococcus mutans Streptococcus mutans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2019.02.033
Streptococcus mutans Streptococcus mutans MIC 0.25 ug.mL-1 10.1016/j.ejmech.2013.12.054
Streptococcus mutans Streptococcus mutans MIC 0.25 ug.mL-1 10.1016/j.ejmech.2019.03.059
Streptococcus mutans Streptococcus mutans MIC 0.5 ug.mL-1 10.1016/j.bmcl.2018.03.037
Streptococcus oralis Streptococcus oralis Activity nan None 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.01538-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.3 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.5 ug ml-1 10.1128/aac.00176-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.0 ug ml-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.0 ug ml-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.3 % 10.1128/aac.01538-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.6 % 10.1128/aac.01538-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.7 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 2.4 % 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 4.0 ug ml-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 4.0 ug ml-1 10.1128/aac.00176-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 4.0 ug ml-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 8.0 ug ml-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 9.4 % 10.1128/aac.00078-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 16.0 ug ml-1 10.1128/aac.00176-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 16.0 ug ml-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 16.5 % 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 18.9 % 10.1128/aac.00078-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 32.0 ug ml-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 59.4 % 10.1128/aac.00078-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 64.0 ug ml-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 81.6 % 10.1128/aac.00078-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 96.6 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 97.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 97.9 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 98.8 % 10.1128/aac.00078-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.1 % 10.1128/aac.00078-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.2 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.4 % 10.1128/aac.00078-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.5 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.8 % 10.1128/aac.00078-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00078-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00845-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1016/j.bmcl.2016.03.106
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1021/acs.jmedchem.8b00644
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1128/aac.01372-06
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 2.3 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 2.5 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 2.6 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 2.7 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 2.8 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 3.0 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 3.3 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 3.4 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 3.6 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 3.7 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 4.1 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 4.4 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 4.7 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 5.2 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 5.5 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 5.8 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 6.0 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 6.3 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 6.6 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 6.7 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 6.8 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 7.1 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae deltalog10CFU/ml 7.4 None 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae EC50 100.0 mg kg-1 10.1016/j.bmcl.2022.128665
Streptococcus pneumoniae Streptococcus pneumoniae ED 28.6 mg kg-1 10.1021/acsmedchemlett.5b00266
Streptococcus pneumoniae Streptococcus pneumoniae ED 50.8 mg kg-1 10.1021/acsmedchemlett.5b00266
Streptococcus pneumoniae Streptococcus pneumoniae ED50 14.3 mg.kg-1 10.1128/aac.00026-09
Streptococcus pneumoniae Streptococcus pneumoniae IZ 12.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae IZ 17.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae IZ 18.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae IZ 21.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae IZ 24.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae IZ 25.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae IZ 26.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae IZ 27.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae IZ 28.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae IZ 31.0 mm 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae MBC 64.0 ug ml-1 10.1016/j.ejmech.2019.06.071
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.008 ug.mL-1 10.1016/j.ejmech.2011.10.048
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1016/j.bmcl.2015.10.027
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1016/j.bmcl.2016.03.050
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.02 ug.mL-1 10.1016/j.bmcl.2004.07.064
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.025 ug.mL-1 10.1016/j.bmc.2009.08.026
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.025 ug.mL-1 10.1021/jm020328y
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.025 ug.mL-1 10.1128/aac.00646-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2021.128450
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.ejmech.2014.09.029
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1021/acsmedchemlett.5b00266
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00026-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00176-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00723-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00959-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.1 ug.mL-1 10.1021/acs.jmedchem.8b00644
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.1 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.00176-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.00845-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.00959-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01000-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1016/j.bmcl.2005.11.064
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1016/j.bmcl.2015.07.044
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1016/j.ejmech.2011.03.026
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01372-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1016/j.bmcl.2015.07.044
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.6b00867
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.8b00644
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1021/jm050035f
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00176-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00959-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01161-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01372-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1016/j.ejmech.2014.09.029
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00026-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00959-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01161-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00959-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01372-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00959-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 3.12 ug.mL-1 10.1016/j.bmcl.2022.128665
Streptococcus pneumoniae Streptococcus pneumoniae MIC 3.13 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2016.03.106
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00176-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00959-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01161-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00082-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00827-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00959-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01161-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1016/j.ejmech.2019.06.071
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 319200.0 nM 10.1016/j.ejmech.2019.01.038
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1021/jm020328y
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.125 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1016/j.bmc.2009.08.026
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.00723-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.00845-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC80 4.0 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.12 ug.mL-1 10.1039/C9MD00120D
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1021/jm020328y
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.00845-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1016/j.bmc.2009.08.026
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.00723-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01197-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MPC 0.5 ug ml-1 10.1128/aac.01372-06
Streptococcus pneumoniae Streptococcus pneumoniae MPC 1.0 ug ml-1 10.1128/aac.01372-06
Streptococcus pneumoniae Streptococcus pneumoniae MPC 8.0 ug ml-1 10.1128/aac.01372-06
Streptococcus pneumoniae Streptococcus pneumoniae Post Antibiotic Effe 1.5 hr 10.1128/aac.01150-06
Streptococcus pneumoniae Streptococcus pneumoniae Ratio 2.0 None 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae Ratio 2.0 None 10.1128/aac.01372-06
Streptococcus pneumoniae Streptococcus pneumoniae Ratio 4.0 None 10.1128/aac.01353-09
Streptococcus pneumoniae Streptococcus pneumoniae Ratio 32.0 None 10.1128/aac.01372-06
Streptococcus pyogenes Streptococcus pyogenes Activity 0.12 % 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes IZ 0.0 mm 10.1128/aac.00780-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.061 ug.mL-1 10.1016/j.bmcl.2005.11.064
Streptococcus pyogenes Streptococcus pyogenes MIC 0.12 ug.mL-1 10.1128/aac.01374-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.125 ug.mL-1 10.1128/aac.00604-06
Streptococcus pyogenes Streptococcus pyogenes MIC 0.125 ug.mL-1 10.1128/aac.00723-10
Streptococcus pyogenes Streptococcus pyogenes MIC 0.2 ug.mL-1 10.1016/j.bmc.2009.08.026
Streptococcus pyogenes Streptococcus pyogenes MIC 0.2 ug.mL-1 10.1016/j.bmcl.2004.07.064
Streptococcus pyogenes Streptococcus pyogenes MIC 0.2 ug.mL-1 10.1021/acs.jmedchem.8b00644
Streptococcus pyogenes Streptococcus pyogenes MIC 0.2 ug.mL-1 10.1021/jm020328y
Streptococcus pyogenes Streptococcus pyogenes MIC 0.2 ug.mL-1 10.1021/jm301650g
Streptococcus pyogenes Streptococcus pyogenes MIC 0.25 ug.mL-1 10.1016/j.bmcl.2015.07.044
Streptococcus pyogenes Streptococcus pyogenes MIC 0.25 ug.mL-1 10.1021/jm050035f
Streptococcus pyogenes Streptococcus pyogenes MIC 0.25 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.25 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.5 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC 1.0 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC 4.0 ug.mL-1 10.1128/aac.00780-09
Streptococcus pyogenes Streptococcus pyogenes MIC 319200.0 nM 10.1016/j.ejmech.2019.01.038
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.12 ug.mL-1 10.1128/aac.01374-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.125 ug.mL-1 10.1128/aac.00723-10
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.25 ug.mL-1 10.1128/aac.00780-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.25 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.25 ug.mL-1 10.1128/aac.01197-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.5 ug.mL-1 10.1128/aac.00780-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.5 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.25 ug.mL-1 10.1039/C9MD00120D
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.25 ug.mL-1 10.1128/aac.00723-10
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.25 ug.mL-1 10.1128/aac.00780-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.25 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.25 ug.mL-1 10.1128/aac.01374-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.5 ug.mL-1 10.1128/aac.00780-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.5 ug.mL-1 10.1128/aac.01197-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.5 ug.mL-1 10.1128/aac.01536-09
Streptococcus salivarius Streptococcus salivarius Activity nan None 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis Activity nan None 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis MIC 0.5 ug.mL-1 10.1021/jm050035f
Streptococcus sanguinis Streptococcus sanguinis MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. Activity nan None 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. MIC 0.03 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. MIC90 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' Activity nan None 10.1128/aac.00845-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC 0.25 ug.mL-1 10.1128/aac.00845-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC50 0.25 ug.mL-1 10.1128/aac.00845-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC90 0.5 ug.mL-1 10.1128/aac.00845-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' Activity nan None 10.1128/aac.00845-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.25 ug.mL-1 10.1128/aac.00845-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 2.0 ug.mL-1 10.1128/aac.00035-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 4.0 ug.mL-1 10.1128/aac.00035-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC50 0.25 ug.mL-1 10.1128/aac.00845-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC90 0.5 ug.mL-1 10.1128/aac.00845-09
Streptococcus viridans Streptococcus viridans MIC 0.06 ug.mL-1 10.1128/aac.01197-09
Streptococcus viridans Streptococcus viridans MIC50 0.12 ug.mL-1 10.1128/aac.01197-09
Streptococcus viridans Streptococcus viridans MIC90 0.25 ug.mL-1 10.1128/aac.01197-09
Veillonella parvula Veillonella parvula MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Vibrio splendidus Vibrio splendidus MIC 0.25 ug.mL-1 10.1128/aac.00070-07
None ADMET Activity 0.0 % 10.1128/aac.01372-06
None ADMET Activity 0.3 ug ml-1 10.1128/aac.00646-06
None ADMET Activity 0.45 ug ml-1 10.1128/aac.00646-06
None ADMET Activity 0.6 ug ml-1 10.1128/aac.00646-06
None ADMET Activity 1.1 ug ml-1 10.1128/aac.00646-06
None ADMET Activity 2.48 ug ml-1 10.1128/aac.00646-06
None ADMET Activity 4.46 ug ml-1 10.1128/aac.00646-06
None ADMET Activity 10.0 % 10.1128/aac.00729-05
None ADMET Activity 20.0 % 10.1128/aac.00749-08
None ADMET Activity 25.0 % 10.1128/aac.00749-08
None ADMET Activity 30.14 % 10.1128/aac.01372-06
None ADMET Activity 77.78 % 10.1128/aac.01372-06
None ADMET AUC 8400.0 ng.hr.mL-1 10.1128/aac.01637-07
None ADMET AUC 8900.0 ng.hr.mL-1 10.1128/aac.01637-07
None ADMET AUC 14300.0 ng.hr.mL-1 10.1128/aac.01637-07
None ADMET AUC 19243.0 ng.hr.mL-1 10.1016/j.ejmech.2019.07.057
None ADMET AUC 19400.0 ng.hr.mL-1 10.1128/aac.01637-07
None ADMET AUC 30000.0 ng.hr.mL-1 10.1039/C9MD00120D
None ADMET CC50 100000.0 nM 10.1021/jm060844e
None ADMET CL 2.2 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL 2.4 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET CL 3.7 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL 10.8 L/hr 10.1128/aac.00802-09
None ADMET CL 11.1 L/hr 10.1128/aac.00802-09
None ADMET CL 11.9 L/hr 10.1128/aac.00802-09
None ADMET CL 12.0 L/hr 10.1128/aac.00802-09
None ADMET CL 12.0 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL 12.1 L/hr 10.1128/aac.00802-09
None ADMET CL 12.4 L/hr 10.1128/aac.00802-09
None ADMET CL 12.7 L/hr 10.1128/aac.00802-09
None ADMET CL 13.0 L/hr 10.1128/aac.00802-09
None ADMET CL 13.3 L/hr 10.1128/aac.00802-09
None ADMET CL 14.2 L/hr 10.1128/aac.00802-09
None ADMET CL 43.0 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL/F 32.3 None 10.1128/aac.01637-07
None ADMET CL/F 46.0 None 10.1128/aac.01637-07
None ADMET CL/F 71.34 None 10.1128/aac.01637-07
None ADMET CL/F 81.1 None 10.1128/aac.01637-07
None ADMET Cmax 1534.48 nM 10.1128/aac.01637-07
None ADMET Cmax 2640.49 nM 10.1128/aac.01637-07
None ADMET Cmax 3537.27 nM 10.1128/aac.01637-07
None ADMET Cmax 6103.03 nM 10.1128/aac.01637-07
None ADMET Cmax 7722.2 nM 10.1039/C9MD00120D
None ADMET Cmax 26853.33 nM 10.1016/j.ejmech.2019.07.057
None ADMET Cmin 0.03 mg/L 10.1128/aac.01637-07
None ADMET Cmin 0.05 mg/L 10.1128/aac.01637-07
None ADMET Cmin 0.06 mg/L 10.1128/aac.01637-07
None ADMET Cmin 0.07 mg/L 10.1128/aac.01637-07
None ADMET DNAUC 18.35 kg.min/L 10.1080/00498250400028197
None ADMET DNAUC 45.09 kg.min/L 10.1080/00498250400028197
None ADMET DNAUC 245.95 kg.min/L 10.1080/00498250400028197
None ADMET DNAUC 372.73 kg.min/L 10.1080/00498250400028197
None ADMET Drug uptake 44.0 ug/g 10.1128/aac.01582-06
None ADMET Drug uptake 66.0 mg Kg-1 10.1128/aac.00306-08
None ADMET Drug uptake 78.0 % 10.1128/aac.01056-08
None ADMET Drug uptake 80.0 % 10.1128/aac.01056-08
None ADMET F 92.0 % 10.1016/j.bmcl.2020.127428
None ADMET fAUC 5300.0 ng.hr.mL-1 10.1128/aac.01637-07
None ADMET fAUC 8400.0 ng.hr.mL-1 10.1128/aac.01637-07
None ADMET fAUC 11600.0 ng.hr.mL-1 10.1128/aac.01637-07
None ADMET fAUC 14300.0 ng.hr.mL-1 10.1128/aac.01637-07
None ADMET Fu 0.8 None 10.1021/acs.jmedchem.8b00114
None ADMET Km 64.6 ug ml-1 10.1128/aac.01253-08
None ADMET MRT 9.7 hr 10.1124/dmd.108.020479
None ADMET Papp 0.9 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 1.0 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 1.22 microg/cm3 10.1128/aac.01253-08
None ADMET Papp 2.2 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 2.49 microg/cm2 10.1128/aac.01253-08
None ADMET Papp 2.7 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 3.1 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 4.08 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 4.35 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 4.42 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 5.0 10'-6 cm/s 10.1128/aac.00733-09
None ADMET Papp 5.25 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 7.74 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 7.8 10'-6 cm/s 10.1128/aac.00733-09
None ADMET Papp 7.9 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 8.05 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 8.07 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 8.3 10'-6 cm/s 10.1128/aac.00733-09
None ADMET Papp 8.86 cm/s 10.1128/aac.00411-10
None ADMET Papp 8.87 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 9.58 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 10.4 10'-6 cm/s 10.1128/aac.00733-09
None ADMET Papp 10.53 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 11.86 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 12.48 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp 13.6 10'-6 cm/s 10.1128/aac.01253-08
None ADMET Papp nan None 10.1128/aac.01253-08
None ADMET PPB 19.0 % 10.1021/acs.jmedchem.1c00375
None ADMET PPB 23.19 % 10.6019/CHEMBL3301361
None ADMET PPB 24.0 % 10.1021/acs.jmedchem.1c00375
None ADMET PPB 30.88 % 10.6019/CHEMBL3301361
None ADMET PPB 31.0 % 10.1021/acs.jmedchem.1c00375
None ADMET PPB 34.42 % 10.6019/CHEMBL3301361
None ADMET PPB 50.0 % 10.1039/C9MD00120D
None ADMET Ratio 0.74 None 10.1128/aac.01637-07
None ADMET Ratio 0.775 None 10.1128/aac.01056-08
None ADMET Ratio 0.803 None 10.1128/aac.01056-08
None ADMET Ratio 0.9 None 10.1128/aac.00733-09
None ADMET Ratio 0.94 None 10.1128/aac.01637-07
None ADMET Ratio 0.953 None 10.1128/aac.01056-08
None ADMET Ratio 1.0 None 10.1128/aac.00414-06
None ADMET Ratio 1.01 None 10.1128/aac.01056-08
None ADMET Ratio 2.0 None 10.1128/aac.01253-08
None ADMET Ratio 2.1 None 10.1128/aac.00733-09
None ADMET RatioAUC/MIC 0.11 None 10.1128/aac.00414-06
None ADMET Selectivity Index 208.96 None 10.1016/j.ejmech.2022.114404
None ADMET Selectivity Index 1434.89 None 10.1016/j.ejmech.2022.114404
None ADMET Stability 92.0 % 10.1021/acs.jmedchem.8b00644
None ADMET T1/2 1.0 hr 10.1016/j.ejmech.2017.11.090
None ADMET T1/2 2.6 hr 10.1016/j.ejmech.2019.07.057
None ADMET T1/2 4.09 hr 10.1128/aac.01637-07
None ADMET T1/2 4.55 hr 10.1128/aac.01637-07
None ADMET T1/2 5.2 hr 10.1128/aac.01637-07
None ADMET T1/2 5.52 hr 10.1128/aac.01637-07
None ADMET T1/2 8.2 hr 10.1124/dmd.108.020479
None ADMET T1/2 11.66 hr 10.1128/aac.00646-06
None ADMET T1/2 11.9 hr 10.1128/aac.00646-06
None ADMET T1/2 12.02 hr 10.1128/aac.00646-06
None ADMET T1/2 12.33 hr 10.1128/aac.00646-06
None ADMET T1/2 12.4 hr 10.1128/aac.00646-06
None ADMET T1/2 12.42 hr 10.1128/aac.00646-06
None ADMET T1/2 13.0 hr 10.1039/C9MD00120D
None ADMET Tmax 0.45 hr 10.1016/j.ejmech.2019.07.057
None ADMET Tmax 2.0 hr 10.1128/aac.01637-07
None ADMET Tmax 4.0 hr 10.1128/aac.01637-07
None ADMET Vc 75.0 l 10.1128/aac.00802-09
None ADMET Vc 91.2 l 10.1128/aac.00802-09
None ADMET Vc 91.4 l 10.1128/aac.00802-09
None ADMET Vc 95.3 l 10.1128/aac.00802-09
None ADMET Vc 97.9 l 10.1128/aac.00802-09
None ADMET Vc 186.0 l 10.1128/aac.00802-09
None ADMET Vc 188.0 l 10.1128/aac.00802-09
None ADMET Vc 190.0 l 10.1128/aac.00802-09
None ADMET Vc 201.0 l 10.1128/aac.00802-09
None ADMET Vdss 1.4 L.kg-1 10.1124/dmd.108.020479
None ADMET Vdss 2.0 L.kg-1 10.1002/jps.20373
None ADMET Vdss 2.7 L.kg-1 10.1002/jps.20373
None ADMET Vdss 3.6 mL/min/kg 10.1002/jps.20373
None ADMET Vdss 4.9 L.kg-1 10.1002/jps.20373
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity HepSE_bilirubinemia 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 5.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 1.0 None 10.1371/journal.pcbi.1002310
None Molecular identity unknown FC 1.1 None 10.1128/aac.00532-09
None Molecular identity unknown FC 1.8 None 10.1128/aac.00532-09
None Molecular identity unknown FC 1.9 None 10.1128/aac.00532-09
None Molecular identity unknown FC 2.9 None 10.1128/aac.00532-09
None Molecular identity unknown FC 5.0 None 10.1128/aac.00532-09
None Molecular identity unknown FC 7.1 None 10.1128/aac.00532-09
None NON-PROTEIN TARGET Activity 0.0 % 10.1128/aac.00481-10
None NON-PROTEIN TARGET Activity 0.0 % 10.1128/aac.00696-08
None NON-PROTEIN TARGET Activity 15.0 % 10.1128/aac.00481-10
None NON-PROTEIN TARGET Activity 28.3 % 10.1128/aac.00081-08
None NON-PROTEIN TARGET Activity 36.4 % 10.1128/aac.01435-06
None NON-PROTEIN TARGET Activity 40.0 % 10.1128/aac.00696-08
None NON-PROTEIN TARGET Activity 45.0 % 10.1128/aac.00418-09
None NON-PROTEIN TARGET Activity 92.0 % 10.1128/aac.00481-10
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00306-08
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00418-09
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00729-05
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00845-09
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.01173-09
None NON-PROTEIN TARGET EC50 5.07 ug.mL-1 10.1128/aac.01761-09
None NON-PROTEIN TARGET EC50 5.21 ug.mL-1 10.1128/aac.01761-09
None NON-PROTEIN TARGET EC50 8.09 ug.mL-1 10.1128/aac.01761-09
None NON-PROTEIN TARGET EC50 8.24 ug.mL-1 10.1128/aac.01761-09
None NON-PROTEIN TARGET EC50 32.0 ug.mL-1 10.1128/aac.01761-09
None NON-PROTEIN TARGET Emax 3.17 log10CFU/ml 10.1128/aac.01761-09
None NON-PROTEIN TARGET Emax 7.0 log10CFU/ml 10.1128/aac.01761-09
None NON-PROTEIN TARGET fAUC/MIC 13.0 None 10.1128/aac.01056-08
None NON-PROTEIN TARGET fAUC/MIC 15.0 None 10.1128/aac.01056-08
None NON-PROTEIN TARGET fAUC/MIC 33.0 None 10.1128/aac.01056-08
None NON-PROTEIN TARGET fAUC/MIC 40.0 None 10.1128/aac.01056-08
None NON-PROTEIN TARGET fAUC/MIC 53.0 None 10.1016/j.bmcl.2013.07.006
None NON-PROTEIN TARGET fAUC/MIC 55.0 None 10.1128/aac.01056-08
None NON-PROTEIN TARGET fAUC/MIC 66.0 None 10.1128/aac.01056-08
None NON-PROTEIN TARGET fCmax/MIC 10.0 None 10.1016/j.bmcl.2013.07.006
None NON-PROTEIN TARGET fT>MIC 80.0 % 10.1016/j.bmcl.2013.07.006
None NON-PROTEIN TARGET Fu 0.6 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 0.3 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 3.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 6.9 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC20 80.0 ug ml-1 10.1128/aac.00729-05
None NON-PROTEIN TARGET IC50 160.0 ug.mL-1 10.1128/aac.00729-05
None NON-PROTEIN TARGET MIC 1.6e-05 ug.mL-1 10.1128/aac.00724-09
None NON-PROTEIN TARGET MIC 3.1e-05 ug.mL-1 10.1128/aac.00724-09
None NON-PROTEIN TARGET MIC 6e-05 ug.mL-1 10.1128/aac.01102-06
None NON-PROTEIN TARGET MIC 6.3e-05 ug.mL-1 10.1128/aac.00724-09
None NON-PROTEIN TARGET MIC 0.0005 ug.mL-1 10.1128/aac.01102-06
None NON-PROTEIN TARGET MIC 0.001 ug.mL-1 10.1128/aac.01102-06
None NON-PROTEIN TARGET MIC 0.016 ug.mL-1 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.016 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC 0.03 ug.mL-1 10.1016/j.bmc.2011.03.018
None NON-PROTEIN TARGET MIC 0.03 ug.mL-1 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.03 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.00121-09
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.00481-10
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.01374-09
None NON-PROTEIN TARGET MIC 0.12 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC 0.125 ug.mL-1 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.125 ug.mL-1 10.1128/aac.00121-09
None NON-PROTEIN TARGET MIC 0.125 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00081-08
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00481-10
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00845-09
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00121-09
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.01761-09
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00121-09
None NON-PROTEIN TARGET MIC 3.85 ug.mL-1 10.1128/aac.01435-06
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC 128.0 ug.mL-1 10.1128/aac.00532-09
None NON-PROTEIN TARGET MIC nan None 10.1016/j.bmcl.2016.11.001
None NON-PROTEIN TARGET MIC nan None 10.1128/aac.00121-09
None NON-PROTEIN TARGET MIC50 6.3e-05 ug.mL-1 10.1128/aac.00724-09
None NON-PROTEIN TARGET MIC50 0.03 ug.mL-1 10.1128/aac.00898-09
None NON-PROTEIN TARGET MIC50 0.032 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC50 0.094 ug.mL-1 10.1128/aac.00056-07
None NON-PROTEIN TARGET MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC50 0.12 ug.mL-1 10.1128/aac.01374-09
None NON-PROTEIN TARGET MIC50 0.25 ug.mL-1 10.1128/aac.00845-09
None NON-PROTEIN TARGET MIC50 0.25 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC50 0.5 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC50 1.0 ug.mL-1 10.1128/aac.00481-10
None NON-PROTEIN TARGET MIC50 1.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.00081-08
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.00898-09
None NON-PROTEIN TARGET MIC50 4.0 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC50 nan None 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC90 0.000125 ug.mL-1 10.1128/aac.00724-09
None NON-PROTEIN TARGET MIC90 0.063 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC90 0.12 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC90 0.125 ug.mL-1 10.1128/aac.00056-07
None NON-PROTEIN TARGET MIC90 0.125 ug.mL-1 10.1128/aac.00898-09
None NON-PROTEIN TARGET MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC90 0.25 ug.mL-1 10.1128/aac.01374-09
None NON-PROTEIN TARGET MIC90 0.5 ug.mL-1 10.1128/aac.00845-09
None NON-PROTEIN TARGET MIC90 0.5 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC90 2.0 ug.mL-1 10.1128/aac.00481-10
None NON-PROTEIN TARGET MIC90 2.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC90 2.0 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC90 8.0 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC90 16.0 ug.mL-1 10.1128/aac.00081-08
None NON-PROTEIN TARGET MIC90 16.0 ug.mL-1 10.1128/aac.00696-08
None NON-PROTEIN TARGET MIC90 16.0 ug.mL-1 10.1128/aac.00898-09
None NON-PROTEIN TARGET MIC90 32.0 ug.mL-1 10.1128/aac.01435-06
None NON-PROTEIN TARGET MIC90 nan None 10.1128/aac.00849-08
None NON-PROTEIN TARGET Ratio 35.3 None 10.1128/aac.01637-07
None NON-PROTEIN TARGET Ratio 59.3 None 10.1128/aac.01637-07
None NON-PROTEIN TARGET Ratio 77.3 None 10.1128/aac.01637-07
None NON-PROTEIN TARGET Ratio 129.3 None 10.1128/aac.01637-07
None NON-PROTEIN TARGET RatioAUC/MIC 17.12 None 10.1128/aac.01761-09
None NON-PROTEIN TARGET RatioAUC/MIC 36.66 None 10.1128/aac.01761-09
None NON-PROTEIN TARGET RatioAUC/MIC 54.8 None 10.1128/aac.01123-07
None NON-PROTEIN TARGET RatioAUC/MIC 88.0 None 10.1016/j.bmcl.2013.07.006
None NON-PROTEIN TARGET RatioAUC/MIC 163.37 None 10.1128/aac.01761-09
None NON-PROTEIN TARGET RatioAUC/MIC 391.56 None 10.1128/aac.01761-09
None NON-PROTEIN TARGET %T>MIC 100.0 % 10.1016/j.bmcl.2013.07.006
None No relevant target LogD -2.9 None 10.1016/j.ejmech.2008.11.009
None No relevant target LogD -1.33 None 10.1021/jm050035f
None No relevant target LogD -0.28 None 10.1128/aac.00733-09
None No relevant target LogD -0.16 None 10.1021/jm050035f
None No relevant target LogD 0.3 None 10.1021/acs.jmedchem.2c00266
None No relevant target LogD 0.63 None 10.1021/acs.jmedchem.1c00375
None No relevant target LogD7.4 -0.18 None 10.6019/CHEMBL3301361
None No relevant target log K 0.1083 None 10.1016/j.ejmech.2019.06.071
None No relevant target LogP 53.8 None 10.1021/jm301650g
None No relevant target LogP 54.0 None 10.1021/acs.jmedchem.8b00644
None No relevant target pKa 6.2 None 10.1007/s11095-013-1232-z
None No relevant target pKa 6.3 None 10.1007/s11095-013-1232-z
None No relevant target pKa 6.7 None 10.1021/acs.jmedchem.1c00375
None No relevant target pKa 9.14 None 10.1007/s11095-013-1232-z
None No relevant target pKa 9.3 None 10.1007/s11095-013-1232-z
None No relevant target pKa1 6.2 None 10.1021/jm050035f
None No relevant target pKa2 9.14 None 10.1021/jm050035f
None No relevant target pKa_A1 6.31 None 10.6019/CHEMBL3301361
None No relevant target pKa_B1 9.51 None 10.6019/CHEMBL3301361
None No relevant target pKa_B2 2.72 None 10.6019/CHEMBL3301361
None No relevant target Ratio 0.02 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 0.14 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 0.15 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 0.16 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 0.21 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 0.24 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 0.25 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 0.73 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 0.89 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 0.95 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 1.0 None 10.1021/acs.jmedchem.0c01541
None No relevant target Ratio 1.05 None 10.1021/acs.jmedchem.0c01541
None No relevant target Solubility 777.0 ug.mL-1 10.1021/jm301650g
None No relevant target Solubility 200000.0 nM 10.1021/acs.jmedchem.2c00266
None Osteoblast Activity 10.0 % 10.1128/aac.00729-05
None Osteoblast IC20 190.0 ug ml-1 10.1128/aac.00729-05
None Osteoblast IC50 400.0 ug.mL-1 10.1128/aac.00729-05
None Unchecked Activity nan None 10.1021/acs.jmedchem.2c00266
None Unchecked CC25 0.5 uM 10.1128/aac.01380-07
None Unchecked CC25 1.0 uM 10.1128/aac.01380-07
None Unchecked CC25 2.5 uM 10.1128/aac.01380-07
None Unchecked CC25 3.5 uM 10.1128/aac.01380-07
None Unchecked CC25 nan None 10.1128/aac.01380-07
None Unchecked Fold_reduction 0.0 None 10.1016/j.bmcl.2003.12.015
None Unchecked Fold_reduction 2.0 None 10.1016/j.bmcl.2003.12.015
None Unchecked Hepatotoxicity (acute) 2.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 0.85 ug.mL-1 10.1016/j.bmc.2010.06.098
None Unchecked IC50 0.85 ug.mL-1 10.1016/j.bmc.2011.03.018
None Unchecked IC50 1.36 ug.mL-1 10.1016/j.bmc.2009.08.026
None Unchecked IC50 5.0 ug.mL-1 10.1016/j.bmc.2010.06.098
None Unchecked IC50 5.0 ug.mL-1 10.1016/j.bmc.2011.03.018
None Unchecked IC50 24.2 ug.mL-1 10.1016/j.bmc.2009.08.026
None Unchecked IC50 190.0 nM 10.1016/j.ejmech.2019.07.052
None Unchecked IC50 800.0 nM 10.1021/jm060844e
None Unchecked IC50 1000.0 nM 10.1021/jm101604v
None Unchecked IC50 1000.0 nM 10.1021/jm2002124
None Unchecked IC50 1000.0 nM 10.1128/aac.00158-07
None Unchecked IC50 1000.0 nM 10.1128/aac.01380-07
None Unchecked IC50 2000.0 nM 10.1128/aac.01380-07
None Unchecked IC50 2500.0 nM 10.1128/aac.01380-07
None Unchecked IC50 2600.0 nM 10.1021/acs.jmedchem.6b00867
None Unchecked IC50 6000.0 nM 10.1128/aac.01380-07
None Unchecked IC50 7000.0 nM 10.1128/aac.01380-07
None Unchecked IC50 11200.0 nM 10.1016/j.ejmech.2014.08.018
None Unchecked IC50 11900.0 nM 10.1021/jm101604v
None Unchecked IC50 11900.0 nM 10.1128/aac.00158-07
None Unchecked IC50 12500.0 nM 10.1021/ml5001728
None Unchecked IC50 25000.0 nM 10.1016/j.bmc.2016.09.012
None Unchecked IC50 nan None 10.1016/j.ejmech.2014.12.046
None Unchecked IC50 nan None 10.1128/aac.01380-07
None Unchecked Inhibition 60.0 % 10.1016/j.ejmech.2014.08.018
None Unchecked Inhibition nan % 10.1016/j.bmcl.2017.01.073
None Unchecked MIC 6.25 ug.mL-1 10.1016/j.bmcl.2022.128665
None Unchecked MIC90 2000.0 nM 10.1021/acsmedchemlett.1c00549
None Unchecked MIC90 4000.0 nM 10.1021/acsmedchemlett.1c00549
None Unchecked Ratio 0.04 None 10.1128/aac.01372-06
None Unchecked Ratio 0.2 None 10.1128/aac.01372-06
None Unchecked Ratio 0.33 None 10.1128/aac.01372-06
None Unchecked Ratio 0.49 None 10.1128/aac.01372-06
None Unchecked Ratio 1.31 None 10.1128/aac.01372-06
None Unchecked Ratio 1.63 None 10.1128/aac.01372-06
None Unchecked Ratio 2.47 None 10.1128/aac.01372-06
None Unchecked Ratio 3.26 None 10.1128/aac.01372-06
None Unchecked Ratio 3.96 None 10.1128/aac.01372-06
None Unchecked Ratio 6.53 None 10.1128/aac.01372-06
None Unchecked Ratio 8.6 None 10.1128/aac.00749-08
None Unchecked Ratio 13.05 None 10.1128/aac.01372-06
None Unchecked Ratio 15.82 None 10.1128/aac.01372-06
None Unchecked Ratio 16.0 None 10.1021/jm500432n
None Unchecked Ratio 17.0 None 10.1016/j.bmcl.2013.07.006
None Unchecked Ratio 19.78 None 10.1128/aac.01372-06
None Unchecked Ratio 34.0 None 10.1128/aac.00177-08
None Unchecked Ratio 39.56 None 10.1128/aac.01372-06
None Unchecked Ratio 56.0 None 10.1128/aac.01637-07
None Unchecked Ratio 64.0 None 10.1021/acs.jmedchem.1c00375
None Unchecked Ratio 79.12 None 10.1128/aac.01372-06
None Unchecked Ratio 90.0 None 10.1128/aac.01520-06
None Unchecked Ratio 95.3 None 10.1128/aac.01637-07
None Unchecked Ratio 121.0 None 10.1128/aac.01520-06
None Unchecked Ratio 158.24 None 10.1128/aac.01372-06
None Unchecked RatioAUC/MIC 54.0 None 10.1128/aac.00177-08
None Unchecked RatioAUC/MIC 59.35 None 10.1128/aac.01036-07
None Unchecked RatioAUC/MIC 1000.0 None 10.1128/aac.01520-06
None Unchecked Ratio IC50 17.79 None 10.1016/j.bmc.2009.08.026
None Unchecked Ratio IC50 117.0 None 10.1016/j.bmc.2009.08.026
None Unchecked Selectivity Index 1024.0 None 10.1016/j.ejmech.2019.07.057
None Unchecked Selectivity Index 1280.0 None 10.1016/j.ejmech.2017.11.090
None Unchecked Selectivity Index nan None 10.1016/j.ejmech.2014.08.018
None Unchecked Selectivity ratio 2.5 None 10.1021/acs.jmedchem.2c00266
None Unchecked Selectivity ratio 2.9 None 10.1021/acs.jmedchem.2c00266
None Unchecked Selectivity ratio 4.0 None 10.1021/acs.jmedchem.6b00867
None Unchecked Selectivity ratio 128.0 None 10.1021/acs.jmedchem.6b00867
None Unchecked TMSW 16.88 % 10.1128/aac.01372-06
None Unchecked TMSW 21.81 % 10.1128/aac.01372-06
None Unchecked TMSW 69.58 % 10.1128/aac.01372-06
None Unchecked TMSW 99.51 % 10.1128/aac.01372-06

Metabolism Information