Farinamycin
AlkaPlorer ID: AK025324
Synonym: 'farinamycin', 'Farinamycin'
IUPAC Name: (3R,4R,5R)-2,4,5-trihydroxy-3-[2-hydroxy-5-(8-hydroxy-4-oxo-3H-quinazolin-2-yl)anilino]-6-iminocyclohexene-1-carboxamide
Structure
SMILES: NC(=O)C1=C(N)[C@@H](O)[C@H](O)[C@@H](NC2=CC(C3=NC4=C(O)C=CC=C4C(=O)N3)=CC=C2O)C1=O
InChI: InChI=1S/C21H19N5O7/c22-13-12(19(23)32)16(29)15(18(31)17(13)30)24-9-6-7(4-5-10(9)27)20-25-14-8(21(33)26-20)2-1-3-11(14)28/h1-6,15,17-18,24,27-28,30-31H,22H2,(H2,23,32)(H,25,26,33)/t15-,17+,18+/m0/s1
InChIKey: OLYXGVRSMULUQN-CGTJXYLNSA-N
Reference
NPASS: NPC322015
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces griseus | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 453.4110000000002
TPSA？: 224.88
MolLogP？: -1.2155999999999991
Number of H-Donors: 8
Number of H-Acceptors: 10
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | Activity | None | None | 10.1021/np2002513 |
| Candida albicans | Candida albicans | Activity | None | None | 10.1021/np2002513 |
| Escherichia coli | Escherichia coli | Activity | None | None | 10.1021/np2002513 |
| Homo sapiens | HeLa | Activity | None | None | 10.1021/np2002513 |
| Homo sapiens | HUVEC | Activity | None | None | 10.1021/np2002513 |
| Homo sapiens | K562 | Activity | None | None | 10.1021/np2002513 |
| Mycolicibacterium vaccae | Mycolicibacterium vaccae | Activity | None | None | 10.1021/np2002513 |
| Penicillium chrysogenum | Penicillium chrysogenum | Activity | None | None | 10.1021/np2002513 |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | Activity | None | None | 10.1021/np2002513 |
| Sporobolomyces salmonicolor | Sporobolomyces salmonicolor | Activity | None | None | 10.1021/np2002513 |
| Staphylococcus aureus | Staphylococcus aureus | Activity | None | None | 10.1021/np2002513 |