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3-[(acetyloxy)methyl]-7-{[1-hydroxy-2-(2-imino-2,3-dihydro-1,3-thiazol-4-yl)-2-(methoxyimino)ethylidene]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

AlkaPlorer ID: AK025478

Synonym: None

IUPAC Name: None

Structure

SMILES: CO/N=C(\C([O-])=N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(C)=O)CS[C@H]12)C1=CSC(=N)N1

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InChI: InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/p-1/b20-9-/t10-,14-/m1/s1

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InChIKey: GPRBEKHLDVQUJE-QSWIMTSFSA-M

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Reference

PubChem CID: 9777579

NPASS: NPC478434

Properties Information

Molecule Weight: 454.4660000000001

TPSA？: 180.56

MolLogP？: -1.1495299999999975

Number of H-Donors: 3

Number of H-Acceptors: 11

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter Acinetobacter MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.00963-09
Acinetobacter baumannii Acinetobacter baumannii Activity nan None 10.1128/aac.01533-08
Acinetobacter baumannii Acinetobacter baumannii Inhibition nan % 10.1128/aac.00471-08
Acinetobacter baumannii Acinetobacter baumannii log10cfu 8.32 None 10.1128/aac.00471-08
Acinetobacter baumannii Acinetobacter baumannii MBC 90.6 mg/L 10.1007/s00044-011-9933-5
Acinetobacter baumannii Acinetobacter baumannii MBC 95.8 mg/L 10.1007/s00044-011-9933-5
Acinetobacter baumannii Acinetobacter baumannii MBC 96.9 mg/L 10.1007/s00044-011-9933-5
Acinetobacter baumannii Acinetobacter baumannii MIC 0.0015 ug.mL-1 10.1128/aac.00471-08
Acinetobacter baumannii Acinetobacter baumannii MIC 0.25 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 1.0 ug.mL-1 10.1128/aac.00072-09
Acinetobacter baumannii Acinetobacter baumannii MIC 1.5 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 3.0 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 3.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 6.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00050-10
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00393-08
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00856-09
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.01164-08
Acinetobacter baumannii Acinetobacter baumannii MIC 12.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.00393-08
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.00856-09
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.01139-06
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.01164-08
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1128/aac.01512-06
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.00393-08
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.01414-07
Acinetobacter baumannii Acinetobacter baumannii MIC 128.0 ug.mL-1 10.1128/aac.01139-06
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00050-10
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00072-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00856-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.00861-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.01037-09
Acinetobacter baumannii Acinetobacter baumannii MIC 256.0 ug.mL-1 10.1128/aac.01512-06
Acinetobacter baumannii Acinetobacter baumannii MIC 32000.0 nM 10.1021/acs.jmedchem.1c00614
Acinetobacter baumannii Acinetobacter baumannii MIC 128000.0 nM 10.1021/jm401335p
Acinetobacter baumannii Acinetobacter baumannii MIC nan None 10.1128/aac.00393-08
Acinetobacter baumannii ADC-11 Kcat 0.2 /s 10.1128/aac.00050-10
Acinetobacter baumannii ADC-11 Kcat/Km 0.1 /uM/s 10.1128/aac.00050-10
Acinetobacter baumannii ADC-11 Ki 2500.0 nM 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase ADC-33 Kcat 1.0 /s 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase ADC-33 Kcat/Km 2.0 /uM/s 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase ADC-33 Ki 500.0 nM 10.1128/aac.00050-10
Acinetobacter genomosp. 3 ADC-14 protein Kcat 0.004 /s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-14 protein Kcat/Km 48.19 /mM/s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-14 protein Km 80.0 nM 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-16 protein Kcat 0.07 /s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-16 protein Kcat/Km 211.84 /mM/s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-16 protein Km 320.0 nM 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-18 protein Kcat 0.06 /s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-18 protein Kcat/Km 306.93 /mM/s 10.1128/aac.00485-08
Acinetobacter genomosp. 3 ADC-18 protein Km 200.0 nM 10.1128/aac.00485-08
Acinetobacter lwoffii Acinetobacter lwoffii MIC nan None 10.1128/aac.00598-10
Acinetobacter pittii Acinetobacter pittii MIC 4.0 ug.mL-1 10.1128/aac.00485-08
Acinetobacter pittii Acinetobacter pittii MIC 12.0 ug.mL-1 10.1128/aac.00485-08
Acinetobacter pittii Acinetobacter pittii MIC 16.0 ug.mL-1 10.1128/aac.00485-08
Acinetobacter pittii Acinetobacter pittii MIC 24.0 ug.mL-1 10.1128/aac.00485-08
Acinetobacter sp. Acinetobacter sp. Activity 8.0 % 10.1128/aac.01808-09
Aeromonas allosaccharophila Extended-spectrum beta-lactamase PER-6 Kcat 40.0 /s 10.1128/aac.01585-09
Aeromonas allosaccharophila Extended-spectrum beta-lactamase PER-6 Kcat/Km 45.0 /uM/s 10.1128/aac.01585-09
Aeromonas allosaccharophila Extended-spectrum beta-lactamase PER-6 Km 900000.0 nM 10.1128/aac.01585-09
Aeromonas caviae Aeromonas caviae Activity 73.0 % 10.1128/aac.00002-08
Aeromonas caviae Aeromonas caviae MIC 256.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Aeromonas caviae Aeromonas caviae MIC 258.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Aeromonas caviae IMP-19 Kcat 20.1 /s 10.1128/aac.01462-06
Aeromonas caviae IMP-19 Kcat/Km 0.33 None 10.1128/aac.01462-06
Aeromonas caviae IMP-19 Km 61000.0 nM 10.1128/aac.01462-06
Aeromonas hydrophila Aeromonas hydrophila Activity 79.0 % 10.1128/aac.00002-08
Aeromonas hydrophila Aeromonas hydrophila IZ 14.7 mm 10.1016/j.bmc.2013.09.041
Aeromonas hydrophila Aeromonas hydrophila MIC 8.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Aeromonas hydrophila Aeromonas hydrophila MIC 256.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Aeromonas sobria Aeromonas sobria Activity 95.0 % 10.1128/aac.00002-08
Aeromonas sp. Aeromonas sp. MIC 32.0 ug.mL-1 10.1128/aac.00770-08
Alcaligenes Alcaligenes MBC 3.12 ug ml-1 10.1021/jm00388a003
Alcaligenes Alcaligenes MIC 1.56 ug.mL-1 10.1021/jm00388a003
Anaerococcus prevotii Anaerococcus prevotii MIC 8.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Aspergillus flavus Aspergillus flavus DIZ nan None 10.1016/j.bmcl.2016.03.117
Aspergillus flavus Aspergillus flavus MIC nan None 10.1016/j.bmcl.2016.03.117
Aspergillus fumigatus Aspergillus fumigatus IC50 200.0 nM 10.1021/acs.jnatprod.9b00187
Bacillus Bacillus MBC 29.73 ug ml-1 10.1021/jm00388a003
Bacillus Bacillus MIC 25.0 ug.mL-1 10.1021/jm00388a003
Bacillus anthracis Beta-lactamase Kcat 0.2 /s 10.1128/aac.00537-07
Bacillus cereus Bacillus cereus IZ 14.0 mm 10.1016/j.ejmech.2006.09.023
Bacillus cereus Bacillus cereus IZ 14.0 mm 10.1016/j.ejmech.2007.01.011
Bacillus cereus Bacillus cereus IZ 18.0 mm 10.1016/j.ejmech.2008.02.038
Bacillus cereus Bacillus cereus IZ 26.8 mm 10.1016/j.bmc.2013.09.041
Bacillus cereus Bacillus cereus IZ 54.0 mm 10.1016/j.ejmech.2009.07.003
Bacillus cereus Bacillus cereus MIC 0.25 ug.mL-1 10.1016/j.bmc.2013.09.041
Bacillus cereus Bacillus cereus MIC 10.0 ug.mL-1 10.1021/np900047p
Bacillus clausii Beta-lactamase Activity 0.3 None 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat 22.0 /s 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat/Km 0.03 /uM/s 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Km 790000.0 nM 10.1128/aac.00537-07
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Potency 63095.7 nM None
Bacillus subtilis Bacillus subtilis MIC 0.78 ug.mL-1 10.1016/j.ejmech.2011.05.028
Bacillus subtilis Bacillus subtilis MIC 0.78 ug.mL-1 10.1016/j.ejmech.2016.10.010
Bacillus subtilis Bacillus subtilis MIC 2.0 ug.mL-1 10.1021/np000506v
Bacillus subtilis Bacillus subtilis MIC 8.0 ug.mL-1 10.1021/np900047p
Bacillus subtilis Bacillus subtilis MIC 50.0 ug.mL-1 10.1128/aac.01436-08
Bacillus subtilis Bacillus subtilis MIC 1000.0 nM 10.1021/acs.jmedchem.1c00614
Bacillus subtilis Bacillus subtilis MIC 12500.0 ug.mL-1 10.1021/np500022w
Bacillus subtilis Bacillus subtilis MIC80 0.78 ug.mL-1 10.1016/j.ejmech.2011.04.053
Bacillus subtilis Bacillus subtilis MIC80 0.78 ug.mL-1 10.1016/j.ejmech.2012.05.013
Bacillus thuringiensis Bacillus thuringiensis MIC 12.5 ug.mL-1 10.1128/aac.01436-08
Bacteroides fragilis Bacteroides fragilis MIC 1.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Bacteroides fragilis Bacteroides fragilis MIC 2.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Bacteroides fragilis Bacteroides fragilis MIC 4.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Bacteroides fragilis Bacteroides fragilis MIC 8.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Bacteroides fragilis Bacteroides fragilis MIC 16.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Bacteroides fragilis Bacteroides fragilis MIC 128.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 128.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Burkholderia cenocepacia Burkholderia cenocepacia MIC 1.0 ug.mL-1 10.1128/aac.00946-08
Burkholderia cenocepacia Burkholderia cenocepacia MIC 4.0 ug.mL-1 10.1128/aac.00946-08
Burkholderia cenocepacia Burkholderia cenocepacia MIC 512.0 ug.mL-1 10.1128/aac.00946-08
Burkholderia cenocepacia PenB class A beta-lactamase Kcat 20.0 /s 10.1128/aac.00946-08
Burkholderia cenocepacia PenB class A beta-lactamase Kcat/Km 130.0 /uM/s 10.1128/aac.00946-08
Burkholderia cenocepacia PenB class A beta-lactamase Km 150000.0 nM 10.1128/aac.00946-08
Campylobacter coli Campylobacter coli MIC 2.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC 4.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC50 4.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC90 8.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 0.25 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 1.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 2.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 4.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 8.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 16.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC50 4.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC90 8.0 ug.mL-1 10.1128/aac.01655-08
Candida albicans Candida albicans DIZ nan None 10.1016/j.bmcl.2016.03.117
Candida albicans Candida albicans IC50 200.0 nM 10.1021/acs.jnatprod.9b00187
Candida albicans Candida albicans IZ nan None 10.1016/j.bmcl.2006.05.021
Candida albicans Candida albicans MIC 145.0 ug.mL-1 10.1021/jm960810e
Candida albicans Candida albicans MIC nan None 10.1016/j.bmcl.2016.03.117
Candida albicans Candida albicans MIC nan None 10.1016/j.ejmech.2011.05.028
Candida albicans Candida albicans MIC nan None 10.1016/j.ejmech.2016.10.010
Candida albicans Candida albicans MIC nan None 10.1021/np900047p
Candida albicans Candida albicans MIC80 nan None 10.1016/j.bmcl.2016.06.006
Canis lupus familiaris Canis familiaris AUC 46700.0 ng.hr.mL-1 10.1021/jm00092a015
Carnobacterium divergens Carnobacterium divergens MIC 256.0 ug.mL-1 10.1128/aac.01145-07
Carnobacterium divergens Carnobacterium divergens MIC nan None 10.1128/aac.01145-07
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Chryseobacterium indologenes Chryseobacterium indologenes Activity 32.0 ug ml-1 10.1128/aac.00083-07
Chryseobacterium indologenes Chryseobacterium indologenes MIC 32.0 ug.mL-1 10.1128/aac.01607-08
Chryseobacterium indologenes IND-like metallo-beta-lactamase Kcat/Km 3.1 10'4/M/s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-2 Kcat/Km 9.0 10'5/M/s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-6 Kcat 8.0 /s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-6 Kcat/Km 2.4 10'5/M/s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-6 Km 33000.0 nM 10.1128/aac.01607-08
Citrobacter amalonaticus Citrobacter amalonaticus MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Citrobacter amalonaticus Citrobacter amalonaticus MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Citrobacter freundii Citrobacter freundii Activity 43.0 % 10.1128/aac.00426-09
Citrobacter freundii Citrobacter freundii Activity 67.0 % 10.1128/aac.01808-09
Citrobacter freundii Citrobacter freundii MIC 0.032 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 0.064 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 0.125 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 1.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 2.0 ug.mL-1 10.1128/aac.00616-07
Citrobacter freundii Citrobacter freundii MIC 8.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 16.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 32.0 ug.mL-1 10.1021/jm00029a012
Citrobacter freundii Citrobacter freundii MIC 32.0 ug.mL-1 10.1021/jm00113a026
Citrobacter freundii Citrobacter freundii MIC 32.0 ug.mL-1 10.1128/aac.01405-06
Citrobacter freundii Citrobacter freundii MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Citrobacter freundii Citrobacter freundii MIC 64.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 64.0 ug.mL-1 10.1128/aac.00886-08
Citrobacter freundii Citrobacter freundii MIC 64.0 ug.mL-1 10.1128/aac.01312-09
Citrobacter freundii Citrobacter freundii MIC 64.0 ug.mL-1 10.1128/aac.01337-07
Citrobacter freundii Citrobacter freundii MIC 64.0 ug.mL-1 10.1128/aac.01395-06
Citrobacter freundii Citrobacter freundii MIC 128.0 ug.mL-1 10.1021/jm00106a031
Citrobacter freundii Citrobacter freundii MIC 128.0 ug.mL-1 10.1021/jm00163a013
Citrobacter freundii Citrobacter freundii MIC 128.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 128.0 ug.mL-1 10.1128/aac.01099-09
Citrobacter freundii Citrobacter freundii MIC 256.0 ug.mL-1 10.1128/aac.00830-08
Citrobacter freundii Citrobacter freundii MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Citrobacter freundii PER-2 beta-lactamase Activity 113.0 % 10.1128/aac.01395-06
Citrobacter freundii PER-2 beta-lactamase Kcat 34.0 /s 10.1128/aac.01395-06
Citrobacter freundii PER-2 beta-lactamase Kcat/Km 0.76 /uM/s 10.1128/aac.01395-06
Citrobacter freundii PER-2 beta-lactamase Km 46000.0 nM 10.1128/aac.01395-06
Citrobacter gillenii Gil1 Kcat 7.0 /s 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Kcat/Km 10.0 /mM/s 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Km 714000.0 nM 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Ratio 0.2 None 10.1128/aac.01152-06
Citrobacter koseri Citrobacter koseri MIC 2.0 ug.mL-1 10.1128/aac.01634-07
Citrobacter koseri Citrobacter koseri MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Clostridium butyricum Clostridium butyricum MIC 1.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Clostridium perfringens Clostridium perfringens IZ 28.5 mm 10.1016/j.bmc.2013.09.041
Clostridium perfringens Clostridium perfringens MIC 0.1 ug.mL-1 10.1016/j.bmc.2013.09.041
Clostridium perfringens Clostridium perfringens MIC 0.25 ug.mL-1 10.1016/S0960-894X(01)80927-6
Clostridium perfringens Clostridium perfringens MIC 0.5 ug.mL-1 10.1016/S0960-894X(01)80927-6
Clostridium perfringens Clostridium perfringens MIC 2.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Clostridium septicum Clostridium septicum MIC 128.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Clostridium sporogenes Clostridium sporogenes MIC 0.5 ug.mL-1 10.1016/S0960-894X(01)80927-6
Corynebacterium jeikeium Corynebacterium jeikeium MIC 8.0 ug.mL-1 10.1128/aac.01569-09
Corynebacterium jeikeium Corynebacterium jeikeium MIC50 32.0 ug.mL-1 10.1128/aac.01569-09
Corynebacterium jeikeium Corynebacterium jeikeium MIC90 32.0 ug.mL-1 10.1128/aac.01569-09
Cryptococcus neoformans Cryptococcus neoformans IC50 200.0 nM 10.1021/acs.jnatprod.9b00187
Elizabethkingia meningoseptica GOB-1 metallo-beta-lactamase Kcat/Km 8.5 10'5/M/s 10.1128/aac.01062-07
Enterobacter Enterobacter MBC 1.97 ug ml-1 10.1021/jm00388a003
Enterobacter Enterobacter MIC 0.12 ug.mL-1 10.1128/aac.01614-06
Enterobacter Enterobacter MIC 0.31 ug.mL-1 10.1021/jm00388a003
Enterobacter Enterobacter MIC 2.0 ug.mL-1 10.1128/aac.01614-06
Enterobacter Enterobacter MIC 32.0 ug.mL-1 10.1128/aac.01614-06
Enterobacter Enterobacter MIC 128.0 ug.mL-1 10.1128/aac.01614-06
Enterobacter Enterobacter MIC 256.0 ug.mL-1 10.1128/aac.01614-06
Enterobacter cloacae Enterobacter cloacae Activity 49.0 % 10.1128/aac.00426-09
Enterobacter cloacae Enterobacter cloacae Activity 62.0 % 10.1128/aac.01808-09
Enterobacter cloacae Enterobacter cloacae Activity 97.8 % 10.1128/aac.01195-06
Enterobacter cloacae Enterobacter cloacae ED50 50.0 mg.kg-1 10.1021/jm00029a012
Enterobacter cloacae Enterobacter cloacae IZ 0.0 mm 10.1016/j.bmcl.2006.05.021
Enterobacter cloacae Enterobacter cloacae LD50 50.0 None 10.1021/jm00029a012
Enterobacter cloacae Enterobacter cloacae MIC 0.007 ug.mL-1 10.1016/s0960-894x(00)00130-x
Enterobacter cloacae Enterobacter cloacae MIC 0.03 ug.mL-1 10.1021/jm00107a035
Enterobacter cloacae Enterobacter cloacae MIC 0.032 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 0.125 ug.mL-1 10.1021/jm00029a012
Enterobacter cloacae Enterobacter cloacae MIC 0.125 ug.mL-1 10.1021/jm00106a031
Enterobacter cloacae Enterobacter cloacae MIC 0.125 ug.mL-1 10.1021/jm00131a005
Enterobacter cloacae Enterobacter cloacae MIC 0.25 ug.mL-1 10.1021/jm00066a006
Enterobacter cloacae Enterobacter cloacae MIC 0.25 ug.mL-1 10.1021/jm00170a011
Enterobacter cloacae Enterobacter cloacae MIC 0.25 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 0.25 ug.mL-1 10.1128/aac.01082-06
Enterobacter cloacae Enterobacter cloacae MIC 0.5 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1128/aac.01099-09
Enterobacter cloacae Enterobacter cloacae MIC 4.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 8.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 8.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1021/jm00107a035
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1021/jm00131a005
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1021/jm00163a013
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1021/jm00170a011
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.00163-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.00616-07
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.00882-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.01534-08
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1021/jm00029a012
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1021/jm00106a031
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1021/jm00113a026
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1128/aac.00616-07
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1128/aac.01431-06
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1128/aac.01534-08
Enterobacter cloacae Enterobacter cloacae MIC 100.0 ug.mL-1 10.1016/s0960-894x(00)00130-x
Enterobacter cloacae Enterobacter cloacae MIC 128.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Enterobacter cloacae Enterobacter cloacae MIC 128.0 ug.mL-1 10.1128/aac.01534-08
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1021/jm00107a035
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00830-08
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.01534-08
Enterobacter cloacae Enterobacter cloacae MIC 512.0 ug.mL-1 10.1128/aac.01312-09
Enterobacter cloacae IMI-1 Kcat 3.4 /s 10.1128/aac.00491-07
Enterobacter cloacae IMI-1 Kcat/Km 18.0 /mM/s 10.1128/aac.00491-07
Enterobacter cloacae IMI-1 Km 190000.0 nM 10.1128/aac.00491-07
Enterobacter hormaechei Enterobacter hormaechei MIC 64.0 ug.mL-1 10.1128/aac.01592-08
Enterobacteriaceae Enterobacteriaceae Activity 6.0 % 10.1128/aac.01808-09
Enterobacteriaceae Enterobacteriaceae Activity 6.9 % 10.1128/aac.00044-07
Enterobacteriaceae Enterobacteriaceae Activity 41.3 % 10.1128/aac.00044-07
Enterococcus faecalis Enterococcus faecalis IZ 22.0 mm 10.1016/j.bmcl.2006.05.021
Enterococcus faecalis Enterococcus faecalis IZ 23.5 mm 10.1016/j.bmc.2013.09.041
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1021/jm00029a012
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1021/jm00113a026
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1128/aac.01569-09
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1016/j.bmc.2011.03.060
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1016/j.bmc.2013.09.041
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/j.bmcl.2012.03.079
Enterococcus faecalis Enterococcus faecalis MIC 40.0 ug.mL-1 10.1021/np900047p
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1016/0960-894X(95)00090-G
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1016/j.bmcl.2012.03.079
Enterococcus faecalis Enterococcus faecalis MIC 128.0 ug.mL-1 10.1021/jm00163a013
Enterococcus faecalis Enterococcus faecalis MIC 400.0 nM 10.1021/acs.jnatprod.6b00011
Enterococcus faecalis Enterococcus faecalis MIC 128000.0 nM 10.1021/jm401335p
Enterococcus faecalis Enterococcus faecalis MIC 512000.0 nM 10.1021/acs.jmedchem.1c00614
Enterococcus faecalis Enterococcus faecalis MIC50 64.0 ug.mL-1 10.1128/aac.01569-09
Enterococcus faecalis Enterococcus faecalis MIC90 64.0 ug.mL-1 10.1128/aac.01569-09
Enterococcus faecium Enterococcus faecium MIC 0.5 ug.mL-1 10.1016/j.bmc.2011.03.060
Enterococcus faecium Enterococcus faecium MIC 0.5 ug.mL-1 10.1128/aac.01569-09
Enterococcus faecium Enterococcus faecium MIC 1.0 ug.mL-1 10.1016/j.bmcl.2012.03.079
Enterococcus faecium Enterococcus faecium MIC 64.0 ug.mL-1 10.1016/j.bmcl.2012.03.079
Enterococcus faecium Enterococcus faecium MIC 64.0 ug.mL-1 10.1128/aac.01569-09
Enterococcus faecium Enterococcus faecium MIC 128.0 ug.mL-1 10.1021/jm00170a011
Enterococcus faecium Enterococcus faecium MIC 4096.0 ug.mL-1 10.1016/j.bmc.2021.116128
Enterococcus faecium Enterococcus faecium MIC50 64.0 ug.mL-1 10.1128/aac.01569-09
Enterococcus faecium Enterococcus faecium MIC90 64.0 ug.mL-1 10.1128/aac.01569-09
Enterococcus sp. Enterococcus sp. MIC 0.25 ug.mL-1 10.1128/aac.01569-09
Enterococcus sp. Enterococcus sp. MIC50 64.0 ug.mL-1 10.1128/aac.01569-09
Enterococcus sp. Enterococcus sp. MIC90 64.0 ug.mL-1 10.1128/aac.01569-09
Escherichia coli Beta-lactamase ACC-4 Kcat 2.7 /s 10.1128/aac.00389-07
Escherichia coli Beta-lactamase ACC-4 Kcat/Km 0.29 /s/microM 10.1128/aac.00389-07
Escherichia coli Beta-lactamase ACC-4 Km 9400.0 nM 10.1128/aac.00389-07
Escherichia coli Beta-lactamase CTX-M Activity 95.0 % 10.1128/aac.00218-07
Escherichia coli Beta-lactamase CTX-M Activity 140.0 % 10.1128/aac.00218-07
Escherichia coli Beta-lactamase CTX-M Kcat 180.0 /s 10.1128/aac.00218-07
Escherichia coli Beta-lactamase CTX-M Kcat/Km 6.9 /s/microM 10.1128/aac.00218-07
Escherichia coli Beta-lactamase CTX-M Km 26000.0 nM 10.1128/aac.00218-07
Escherichia coli Beta-lactamase SCO-1 Activity 1.0 None 10.1128/aac.01439-06
Escherichia coli Beta-lactamase SHV-1 Kcat 0.1 /s 10.1128/aac.01442-09
Escherichia coli Beta-lactamase SHV-1 Kcat/Km nan None 10.1128/aac.01442-09
Escherichia coli Beta-lactamase SHV-1 Km 257000.0 nM 10.1128/aac.01442-09
Escherichia coli Beta-lactamase SHV-11 Kcat 0.01 /s 10.1128/aac.00387-08
Escherichia coli Beta-lactamase SHV-11 Kcat/Km nan None 10.1128/aac.00387-08
Escherichia coli Beta-lactamase SHV-11 Km nan None 10.1128/aac.00387-08
Escherichia coli Beta-lactamase TEM Activity 1.0 None 10.1128/aac.01439-06
Escherichia coli Beta-lactamase TEM Kcat 0.1 /s 10.1128/aac.00614-07
Escherichia coli Beta-lactamase TEM Kcat/Km nan None 10.1128/aac.00614-07
Escherichia coli Beta-lactamase TEM Km nan None 10.1128/aac.00614-07
Escherichia coli Beta-lactamase Toho-1 Kcat 390.0 /s 10.1128/aac.00098-10
Escherichia coli Beta-lactamase Toho-1 Kcat/Km 1.9 10'6/s/M 10.1128/aac.00098-10
Escherichia coli Beta-lactamase Toho-1 Km 210000.0 nM 10.1128/aac.00098-10
Escherichia coli BlaVIM-1 Kcat 169.0 /s 10.1128/aac.00017-09
Escherichia coli BlaVIM-1 Kcat 170.0 /s 10.1128/aac.00458-09
Escherichia coli BlaVIM-1 Kcat/Km 0.68 /s/microM 10.1128/aac.00017-09
Escherichia coli BlaVIM-1 Kcat/Km 0.7 /uM/s 10.1128/aac.00458-09
Escherichia coli BlaVIM-1 Km 250000.0 nM 10.1128/aac.00458-09
Escherichia coli CMT-type beta lactamase Kcat 0.08 /s 10.1128/aac.00614-07
Escherichia coli CMT-type beta lactamase Kcat/Km 0.0004 None 10.1128/aac.00614-07
Escherichia coli CMT-type beta lactamase Km 207.5 /s/microM 10.1128/aac.00614-07
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.00551-10
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.01509-06
Escherichia coli Escherichia coli Activity 0.125 ug ml-1 10.1128/aac.00083-07
Escherichia coli Escherichia coli Activity 1.1 % 10.1128/aac.00551-10
Escherichia coli Escherichia coli Activity 3.3 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 5.0 % 10.1128/aac.00426-09
Escherichia coli Escherichia coli Activity 16.0 ug ml-1 10.1128/aac.00083-07
Escherichia coli Escherichia coli Activity 38.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 95.8 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 96.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 97.0 % 10.1128/aac.00426-09
Escherichia coli Escherichia coli Activity 98.7 % 10.1128/aac.00265-10
Escherichia coli Escherichia coli Activity 99.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity 99.0 % 10.1128/aac.01808-09
Escherichia coli Escherichia coli Activity 100.0 % 10.1128/aac.01412-06
Escherichia coli Escherichia coli Activity nan None 10.1016/j.bmcl.2016.10.004
Escherichia coli Escherichia coli Activity nan None 10.1016/j.ejmech.2022.114571
Escherichia coli Escherichia coli Activity nan None 10.1021/acs.jmedchem.0c00040
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00533-09
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00614-07
Escherichia coli Escherichia coli ED50 0.27 mg.kg-1 10.1021/jm00388a003
Escherichia coli Escherichia coli ED50 0.37 mg.kg-1 10.1021/jm00106a031
Escherichia coli Escherichia coli ED50 1.7 mg.kg-1 10.1021/jm00163a013
Escherichia coli Escherichia coli IC50 100.0 nM 10.1021/acs.jnatprod.9b00187
Escherichia coli Escherichia coli ICmax 2048.0 ug ml-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli Inhibition 10.0 % 10.1128/aac.00471-08
Escherichia coli Escherichia coli Inhibition nan % 10.1128/aac.00471-08
Escherichia coli Escherichia coli IZ 6.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 7.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 7.1 mm 10.1074/jbc.m700084200
Escherichia coli Escherichia coli IZ 8.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 8.8 mm 10.1128/aac.00576-07
Escherichia coli Escherichia coli IZ 9.0 mm 10.1074/jbc.m700084200
Escherichia coli Escherichia coli IZ 10.0 mm 10.1016/j.ejmech.2006.09.023
Escherichia coli Escherichia coli IZ 10.0 mm 10.1016/j.ejmech.2007.01.011
Escherichia coli Escherichia coli IZ 10.0 mm 10.1016/j.ejmech.2008.02.038
Escherichia coli Escherichia coli IZ 10.0 mm 10.1016/j.ejmech.2009.07.003
Escherichia coli Escherichia coli IZ 10.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 10.3 mm 10.1074/jbc.m700084200
Escherichia coli Escherichia coli IZ 11.0 mm 10.1016/j.ejmech.2020.112832
Escherichia coli Escherichia coli IZ 11.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 12.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 12.9 mm 10.1074/jbc.m700084200
Escherichia coli Escherichia coli IZ 13.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 14.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 15.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 16.0 mm 10.1128/aac.00167-07
Escherichia coli Escherichia coli IZ 16.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 17.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 18.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 21.0 mm 10.1016/j.bmcl.2006.05.021
Escherichia coli Escherichia coli IZ 21.0 mm 10.1128/aac.00576-07
Escherichia coli Escherichia coli IZ 22.8 mm 10.1016/j.bmc.2013.09.041
Escherichia coli Escherichia coli IZ 23.0 mm 10.1128/aac.00547-09
Escherichia coli Escherichia coli IZ 24.0 mm 10.1128/aac.00547-09
Escherichia coli Escherichia coli IZ 26.0 mm 10.1016/j.bmcl.2016.03.117
Escherichia coli Escherichia coli IZ 26.0 mm 10.1128/aac.00547-09
Escherichia coli Escherichia coli IZ 28.0 mm 10.1016/j.bmcl.2006.05.021
Escherichia coli Escherichia coli IZ 28.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 29.0 mm 10.1128/aac.00547-09
Escherichia coli Escherichia coli IZ 29.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 30.0 mm 10.1128/aac.00547-09
Escherichia coli Escherichia coli IZ 30.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 31.0 mm 10.1128/aac.00167-07
Escherichia coli Escherichia coli IZ 31.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 32.0 mm 10.1128/aac.00877-08
Escherichia coli Escherichia coli IZ 33.0 mm 10.1128/aac.00547-09
Escherichia coli Escherichia coli IZ 45.0 mm 10.1016/j.ejmech.2014.03.033
Escherichia coli Escherichia coli IZ nan None 10.1016/j.bmcl.2006.05.021
Escherichia coli Escherichia coli log10cfu 8.66 None 10.1128/aac.00471-08
Escherichia coli Escherichia coli MBC 0.25 ug ml-1 10.1021/jm00388a003
Escherichia coli Escherichia coli MBC 1.0 ug ml-1 10.1021/acs.jmedchem.6b00580
Escherichia coli Escherichia coli MBC 17.3 mg/L 10.1007/s00044-011-9933-5
Escherichia coli Escherichia coli MBC 24.5 mg/L 10.1007/s00044-011-9933-5
Escherichia coli Escherichia coli MIC 0.0015 ug.mL-1 10.1128/aac.00471-08
Escherichia coli Escherichia coli MIC 0.002 ug.mL-1 10.1021/jm00107a035
Escherichia coli Escherichia coli MIC 0.004 ug.mL-1 10.1128/aac.01337-07
Escherichia coli Escherichia coli MIC 0.007 ug.mL-1 10.1016/s0960-894x(00)00130-x
Escherichia coli Escherichia coli MIC 0.008 ug.mL-1 10.1128/aac.01337-07
Escherichia coli Escherichia coli MIC 0.01 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 0.0125 ug.mL-1 10.1016/0960-894X(95)00485-C
Escherichia coli Escherichia coli MIC 0.013 ug.mL-1 10.1016/s0960-894x(00)00130-x
Escherichia coli Escherichia coli MIC 0.015 ug.mL-1 10.1128/aac.01442-09
Escherichia coli Escherichia coli MIC 0.016 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 0.016 ug.mL-1 10.1128/aac.01145-07
Escherichia coli Escherichia coli MIC 0.016 ug.mL-1 10.1128/aac.01615-09
Escherichia coli Escherichia coli MIC 0.02 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 0.023 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 0.023 ug.mL-1 10.1128/aac.01473-08
Escherichia coli Escherichia coli MIC 0.025 ug.mL-1 10.1016/s0960-894x(00)00130-x
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1016/0960-894X(95)00090-G
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1021/jm00066a006
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1021/jm00107a035
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1021/jm00131a005
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1021/jm00170a011
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.00175-08
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.00310-09
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01025-07
Escherichia coli Escherichia coli MIC 0.03 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 0.031 ug.mL-1 10.1021/jm00029a012
Escherichia coli Escherichia coli MIC 0.031 ug.mL-1 10.1021/jm00106a031
Escherichia coli Escherichia coli MIC 0.031 ug.mL-1 10.1021/jm00113a026
Escherichia coli Escherichia coli MIC 0.031 ug.mL-1 10.1021/jm00163a013
Escherichia coli Escherichia coli MIC 0.032 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 0.032 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 0.032 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 0.032 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 0.047 ug.mL-1 10.1128/aac.00050-10
Escherichia coli Escherichia coli MIC 0.047 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 0.047 ug.mL-1 10.1128/aac.00239-09
Escherichia coli Escherichia coli MIC 0.047 ug.mL-1 10.1128/aac.00436-09
Escherichia coli Escherichia coli MIC 0.047 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 0.047 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 0.05 ug.mL-1 10.1021/acs.jmedchem.0c00077
Escherichia coli Escherichia coli MIC 0.05 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1016/s0960-894x(01)00587-x
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1021/jm00106a031
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1021/jm00107a035
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1021/jm00113a026
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1021/jm00163a013
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00197-10
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00242-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00427-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00543-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00614-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00693-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00734-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00770-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00791-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00909-06
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.00946-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01062-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01137-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01152-06
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01164-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01180-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01252-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01381-07
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01400-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01442-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01534-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01580-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01581-08
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 0.06 ug.mL-1 10.1128/aac.01834-09
Escherichia coli Escherichia coli MIC 0.063 ug.mL-1 10.1021/jm00029a012
Escherichia coli Escherichia coli MIC 0.063 ug.mL-1 10.1021/jm00113a026
Escherichia coli Escherichia coli MIC 0.063 ug.mL-1 10.1021/jm00163a013
Escherichia coli Escherichia coli MIC 0.063 ug.mL-1 10.1128/aac.01395-06
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00072-09
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00167-07
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00239-09
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00684-07
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.00774-09
Escherichia coli Escherichia coli MIC 0.064 ug.mL-1 10.1128/aac.01011-08
Escherichia coli Escherichia coli MIC 0.094 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 0.094 ug.mL-1 10.1128/aac.00547-09
Escherichia coli Escherichia coli MIC 0.094 ug.mL-1 10.1128/aac.01053-06
Escherichia coli Escherichia coli MIC 0.094 ug.mL-1 10.1128/aac.01440-07
Escherichia coli Escherichia coli MIC 0.1 ug.mL-1 10.1128/aac.00387-08
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.03.008
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00219-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00393-08
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00458-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00547-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00614-07
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00768-10
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00856-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00859-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00878-10
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.00961-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01082-06
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01336-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01439-06
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01456-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01463-07
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01585-09
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01600-06
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1128/aac.01607-08
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1021/acs.jmedchem.6b00580
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00098-10
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00197-10
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00225-10
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00774-09
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01028-07
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01442-09
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01539-07
Escherichia coli Escherichia coli MIC 0.125 ug.mL-1 10.1128/aac.01581-08
Escherichia coli Escherichia coli MIC 0.13 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 0.13 ug.mL-1 10.1128/aac.01137-07
Escherichia coli Escherichia coli MIC 0.17 ug.mL-1 10.1021/jm00388a003
Escherichia coli Escherichia coli MIC 0.19 ug.mL-1 10.1128/aac.00465-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1016/j.bmcl.2012.03.079
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1021/jm00107a035
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1021/jm980476h
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00547-09
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00614-07
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00736-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00858-10
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00946-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01164-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01463-07
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01473-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.01600-06
Escherichia coli Escherichia coli MIC 0.3 ug.mL-1 10.1021/jm00131a005
Escherichia coli Escherichia coli MIC 0.38 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 0.38 ug.mL-1 10.1128/aac.00543-08
Escherichia coli Escherichia coli MIC 0.38 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 0.38 ug.mL-1 10.1128/aac.01473-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/0960-894X(95)00090-G
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.bmc.2013.09.041
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00050-10
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00072-09
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00310-09
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00961-09
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01607-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01672-07
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 0.512 ug.mL-1 10.1016/j.ejmech.2022.114108
Escherichia coli Escherichia coli MIC 0.55 ug.mL-1 10.1021/jm00388a003
Escherichia coli Escherichia coli MIC 0.75 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 0.75 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 0.75 ug.mL-1 10.1128/aac.01580-09
Escherichia coli Escherichia coli MIC 0.8 ug.mL-1 10.1021/acs.jmedchem.0c00077
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00175-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00197-10
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00427-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00899-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01028-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01152-06
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01615-09
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01658-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1128/aac.00436-09
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 1.5 ug.mL-1 10.1128/aac.01658-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00009-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00098-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00175-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00197-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00436-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01011-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01361-09
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.01658-07
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.00771-10
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.01436-08
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 3.0 ug.mL-1 10.1128/aac.01658-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00175-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00736-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00859-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00909-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01011-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01025-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01028-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01053-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01058-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01180-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01439-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01580-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01658-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01672-07
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 5.0 ug.mL-1 10.1021/acs.jmedchem.5b00341
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/acsmedchemlett.7b00428
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00050-10
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00197-10
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00693-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00791-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00858-10
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01025-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01252-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01439-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01539-07
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01561-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01580-09
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 12.0 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 12.0 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 12.0 ug.mL-1 10.1128/aac.01580-09
Escherichia coli Escherichia coli MIC 13.0 ug.mL-1 10.1016/j.bmcl.2016.03.117
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.ejmech.2019.02.024
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.5b00341
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00050-10
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00098-10
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00163-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00219-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00274-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00608-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00642-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01062-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01580-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01658-07
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.01834-09
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1128/aac.00167-07
Escherichia coli Escherichia coli MIC 25.0 ug.mL-1 10.1128/aac.00485-08
Escherichia coli Escherichia coli MIC 31.0 ug.mL-1 10.1128/aac.00274-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/jm2014138
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00009-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00098-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00143-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00274-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00374-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00458-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00638-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00770-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00858-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00859-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00882-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01053-06
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01336-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01451-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01580-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01672-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01834-09
Escherichia coli Escherichia coli MIC 40.0 ug.mL-1 10.1021/np900047p
Escherichia coli Escherichia coli MIC 48.0 ug.mL-1 10.1128/aac.01585-09
Escherichia coli Escherichia coli MIC 60.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1021/jm2014138
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00009-10
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00111-10
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00279-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00389-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00458-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00734-08
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00841-06
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00896-08
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01312-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01320-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01395-06
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01585-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01658-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01834-09
Escherichia coli Escherichia coli MIC 96.0 ug.mL-1 10.1128/aac.01320-07
Escherichia coli Escherichia coli MIC 96.0 ug.mL-1 10.1128/aac.01440-07
Escherichia coli Escherichia coli MIC 100.0 nM 10.1021/jm300820a
Escherichia coli Escherichia coli MIC 120.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 125.0 nM 10.1021/jm401335p
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1074/jbc.m700084200
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00050-10
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00225-10
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00616-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00830-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00886-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01155-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01284-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01337-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01440-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01658-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01834-09
Escherichia coli Escherichia coli MIC 200.0 ug.mL-1 10.1016/j.ejmech.2011.05.028
Escherichia coli Escherichia coli MIC 200.0 ug.mL-1 10.1016/j.ejmech.2016.10.010
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00050-10
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00072-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00098-10
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00133-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00219-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00461-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00465-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00688-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00746-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00774-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00878-10
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01060-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01456-09
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01534-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01539-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01658-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01762-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00017-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00098-10
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00458-09
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00878-10
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01337-07
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01431-06
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 1000.0 nM 10.1021/acs.jmedchem.1c00614
Escherichia coli Escherichia coli MIC 1024.0 ug.mL-1 10.1021/acsmedchemlett.7b00428
Escherichia coli Escherichia coli MIC 1024.0 ug.mL-1 10.1128/aac.00098-10
Escherichia coli Escherichia coli MIC 1024.0 ug.mL-1 10.1128/aac.01431-08
Escherichia coli Escherichia coli MIC 1700.0 nM 10.1021/acs.jnatprod.6b00011
Escherichia coli Escherichia coli MIC 2048.0 ug.mL-1 10.1128/aac.00227-08
Escherichia coli Escherichia coli MIC 2100.0 nM 10.1021/jm300820a
Escherichia coli Escherichia coli MIC 8192.0 ug.mL-1 10.1016/j.bmc.2021.116128
Escherichia coli Escherichia coli MIC 13600.0 nM 10.1016/j.ejmech.2017.08.066
Escherichia coli Escherichia coli MIC 16000.0 ug.mL-1 10.1016/j.bmc.2021.116128
Escherichia coli Escherichia coli MIC 128000.0 nM 10.1021/jm401335p
Escherichia coli Escherichia coli MIC 134000.0 nM 10.1021/jm300820a
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.00393-08
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.01472-06
Escherichia coli Escherichia coli MIC50 32.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC50 32.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC50 256.0 ug.mL-1 10.1128/aac.00171-08
Escherichia coli Escherichia coli MIC50 256.0 ug.mL-1 10.1128/aac.01509-06
Escherichia coli Escherichia coli MIC80 200.0 ug.mL-1 10.1016/j.ejmech.2011.04.053
Escherichia coli Escherichia coli MIC80 200.0 ug.mL-1 10.1016/j.ejmech.2012.05.013
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1128/aac.00883-08
Escherichia coli Escherichia coli MIC90 32.0 ug.mL-1 10.1128/aac.01412-06
Escherichia coli Escherichia coli MIC90 128.0 ug.mL-1 10.1128/aac.00171-08
Escherichia coli Escherichia coli MIC90 256.0 ug.mL-1 10.1128/aac.00171-08
Escherichia coli Escherichia coli MIC90 256.0 ug.mL-1 10.1128/aac.01509-06
Escherichia coli Escherichia coli Ratio 2.0 None 10.1016/j.ejmech.2012.03.008
Escherichia coli Escherichia coli Ratio 16.0 None 10.1128/aac.00734-08
Escherichia coli Escherichia coli Stability 20.0 nmol/min 10.1128/aac.00734-08
Escherichia coli Escherichia coli Stability 48.0 nmol/min 10.1128/aac.00734-08
Escherichia coli Escherichia coli Stability 172.0 nmol/min 10.1128/aac.00734-08
Escherichia coli Escherichia coli Stability 368.0 nmol/min 10.1128/aac.00734-08
Escherichia coli Escherichia coli Stability 487.0 nmol/min 10.1128/aac.00734-08
Escherichia coli Escherichia coli Stability 1310.0 nmol/min 10.1128/aac.00734-08
Escherichia coli Escherichia coli Susceptibility nan None 10.1021/jm049652e
Escherichia coli Metallo-beta-lactamase Kcat 25.0 /s 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Kcat 27.5 /s 10.1128/aac.00017-09
Escherichia coli Metallo-beta-lactamase Kcat 70.0 /s 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Kcat 143.0 /s 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Kcat/Km 0.3 /uM/s 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Kcat/Km 0.86 /s/microM 10.1128/aac.00017-09
Escherichia coli Metallo-beta-lactamase Kcat/Km 5.8 uM/hr 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Kcat/Km 5.8 /uM/s 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Kcat/Km 7.5 /uM/s 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Km 12000.0 nM 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Km 19000.0 nM 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase Km 83000.0 nM 10.1128/aac.01336-09
Escherichia coli Metallo-beta-lactamase VIM-19 Kcat 900.0 /s 10.1128/aac.00458-09
Escherichia coli Metallo-beta-lactamase VIM-19 Kcat/Km 30.0 /uM/s 10.1128/aac.00458-09
Escherichia coli Metallo-beta-lactamase VIM-19 Km 30000.0 nM 10.1128/aac.00458-09
Escherichia coli K-12 Penicillin-binding protein 1A Binding affinity 0.1 None 10.1021/jm00029a012
Escherichia coli K-12 Penicillin-binding protein 1A Concentration 0.1 ug ml-1 10.1021/jm00106a031
Escherichia coli K-12 Penicillin-binding protein 1A Inhibition 0.1 % 10.1021/jm00163a013
Escherichia coli K-12 Penicillin-binding protein 1B Binding affinity 0.5 None 10.1021/jm00029a012
Escherichia coli K-12 Penicillin-binding protein 1B Concentration 0.5 ug ml-1 10.1021/jm00106a031
Escherichia coli K-12 Penicillin-binding protein 1B Inhibition 0.5 % 10.1021/jm00163a013
Escherichia coli K-12 Penicillin-binding protein 2 Binding affinity 100.0 None 10.1021/jm00029a012
Escherichia coli K-12 Penicillin-binding protein 2 Concentration 100.0 ug ml-1 10.1021/jm00106a031
Escherichia coli K-12 Penicillin-binding protein 2 Inhibition 100.0 % 10.1021/jm00163a013
Flavobacterium meningosepticum Carbapenem-hydrolyzing beta-lactamase BlaB-1 Kcat/Km 7.9 10'5/M/s 10.1128/aac.01607-08
Fluoribacter gormanii FEZ-1 protein Kcat/Km 2.4 10'6/M/s 10.1128/aac.01062-07
Fusobacterium necrophorum Fusobacterium necrophorum MIC 1.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Fusobacterium nucleatum Fusobacterium nucleatum MIC 0.5 ug.mL-1 10.1016/S0960-894X(01)80927-6
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Potency 14091.9 nM None
Haemophilus influenzae Haemophilus influenzae Activity 0.0 % 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae Activity 0.0 % 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae Activity 0.1 % 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae Activity 0.8 % 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae Activity 1.0 % 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae Activity 99.0 % 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae Activity 99.9 % 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae Activity 100.0 % 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae Inhibition nan % 10.1128/aac.00471-08
Haemophilus influenzae Haemophilus influenzae log10cfu 8.45 None 10.1128/aac.00471-08
Haemophilus influenzae Haemophilus influenzae MIC 0.00016 ug.mL-1 10.1128/aac.00471-08
Haemophilus influenzae Haemophilus influenzae MIC 0.004 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 0.008 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 0.008 ug.mL-1 10.1128/aac.01569-09
Haemophilus influenzae Haemophilus influenzae MIC 0.01 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC 0.015 ug.mL-1 10.1016/s0960-894x(01)00587-x
Haemophilus influenzae Haemophilus influenzae MIC 0.015 ug.mL-1 10.1021/jm00066a006
Haemophilus influenzae Haemophilus influenzae MIC 0.015 ug.mL-1 10.1021/jm00131a005
Haemophilus influenzae Haemophilus influenzae MIC 0.016 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 0.016 ug.mL-1 10.1128/aac.00335-07
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1016/0960-894X(95)00090-G
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1128/aac.00484-10
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1128/aac.01489-09
Haemophilus influenzae Haemophilus influenzae MIC 0.03 ug.mL-1 10.1128/aac.01569-09
Haemophilus influenzae Haemophilus influenzae MIC 0.031 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 0.032 ug.mL-1 10.1016/j.bmc.2011.03.060
Haemophilus influenzae Haemophilus influenzae MIC 0.047 ug.mL-1 10.1128/aac.00335-07
Haemophilus influenzae Haemophilus influenzae MIC 0.06 ug.mL-1 10.1128/aac.01489-09
Haemophilus influenzae Haemophilus influenzae MIC 0.063 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 0.063 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 0.069 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 0.079 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 0.094 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 0.125 ug.mL-1 10.1128/aac.00335-07
Haemophilus influenzae Haemophilus influenzae MIC 0.125 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 0.188 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 0.194 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.00335-07
Haemophilus influenzae Haemophilus influenzae MIC 0.532 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 0.708 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC 1.7 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.008 ug.mL-1 10.1128/aac.01569-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.01 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC50 0.015 ug.mL-1 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.015 ug.mL-1 10.1128/aac.01569-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.016 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC50 0.03 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC50 0.03 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC50 0.031 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC50 0.06 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC50 0.06 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC50 0.063 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.5 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC50 0.5 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC50 0.5 ug.mL-1 10.1128/aac.01569-09
Haemophilus influenzae Haemophilus influenzae MIC50 1.0 ug.mL-1 10.1128/aac.00484-10
Haemophilus influenzae Haemophilus influenzae MIC90 0.015 ug.mL-1 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae MIC90 0.015 ug.mL-1 10.1128/aac.01569-09
Haemophilus influenzae Haemophilus influenzae MIC90 0.031 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC90 0.06 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC90 0.06 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC90 0.12 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC90 0.12 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC90 0.125 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC90 0.25 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC90 0.25 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC90 0.25 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC90 0.5 ug.mL-1 10.1128/aac.00402-08
Haemophilus influenzae Haemophilus influenzae MIC90 0.5 ug.mL-1 10.1128/aac.01569-09
Haemophilus influenzae Haemophilus influenzae MIC90 1.0 ug.mL-1 10.1128/aac.00054-10
Haemophilus influenzae Haemophilus influenzae MIC90 1.0 ug.mL-1 10.1128/aac.00966-09
Haemophilus influenzae Haemophilus influenzae MIC90 4.0 ug.mL-1 10.1128/aac.00354-07
Haemophilus influenzae Haemophilus influenzae MIC90 4.0 ug.mL-1 10.1128/aac.00484-10
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Beta-1 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Chromobox protein homolog 1 Potency 50118.7 nM None
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens DNA polymerase kappa Potency 37685.8 nM None
Homo sapiens DNA polymerase kappa Potency 39810.7 nM None
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Flap endonuclease 1 Potency 4228.4 nM None
Homo sapiens Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Ki nan None None
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone deacetylase 6 Inhibition -25.97 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition -0.34 % 10.6019/CHEMBL4808148
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Potency 11220.2 nM None
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Potency 17782.8 nM None
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens CL 0.18 L/hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens CL 0.22 L/hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens CL 0.26 L/hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens CL 0.3 L/hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens CL 0.36 L/hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens CL 0.4 L/hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens CL 1.37 L/hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens CL 1.38 L/hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens CL 1.46 L/hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens CL 2.7 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL_renal 1.37 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 5.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens T1/2 0.8 hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens T1/2 1.6 hr 10.1128/aac.01696-09
Homo sapiens Homo sapiens Vd 1.82 l 10.1128/aac.01696-09
Homo sapiens Homo sapiens Vd 11.0 l 10.1128/aac.01696-09
Homo sapiens Homo sapiens Vdss 0.28 L.kg-1 10.1016/j.ejmech.2009.06.004
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Kappa opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens Microtubule-associated protein tau Potency 19952.6 nM None
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens Oligopeptide transporter small intestine isoform Ki 30000000.0 nM 10.1016/j.ejpb.2004.07.008
Homo sapiens Oligopeptide transporter small intestine isoform Ki 30000000.0 nM 10.1021/jm048982w
Homo sapiens Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Potency 21331.3 nM None
Homo sapiens Peroxisome proliferator-activated receptor gamma AC50 17000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Peroxisome proliferator-activated receptor gamma AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Plasma Kel 0.197 /hr 10.1128/aac.00636-08
Homo sapiens Plasma K(p,uu,CSF) 0.17 None 10.1021/jm901036q
Homo sapiens Plasma Vd 0.912 L.kg-1 10.1128/aac.00636-08
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 16000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Regulator of G-protein signaling 4 Potency 21192.3 nM None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Serum albumin Kd 12000.0 nM 10.1128/aac.00971-08
Homo sapiens Serum albumin Ratio 0.5 None 10.1128/aac.00971-08
Homo sapiens Serum albumin Ratio 1.0 None 10.1128/aac.00971-08
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens Solute carrier family 15 member 2 Ki 19952623.15 nM 10.1016/j.bmc.2011.06.027
Homo sapiens Solute carrier family 15 member 2 Ki 20000000.0 nM 10.1016/j.bmc.2011.06.027
Homo sapiens Solute carrier family 22 member 11 Ki 6150.0 nM 10.1016/s0014-2999(02)01306-7
Homo sapiens Solute carrier family 22 member 6 Ki 3130.0 nM 10.1016/s0014-2999(02)01306-7
Homo sapiens Solute carrier family 22 member 7 IC50 4680000.0 nM 10.1016/s0014-2999(03)01381-5
Homo sapiens Solute carrier family 22 member 8 Inhibition nan % 10.1124/dmd.112.049569
Homo sapiens Solute carrier family 22 member 8 Ki 290.0 nM 10.1016/s0014-2999(02)01306-7
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vitamin D receptor Potency 50118.7 nM None
Homo sapiens Vitamin D receptor Potency 70794.6 nM None
Janthinobacterium lividum THIN-B proetin Kcat/Km 2.0 10'6/M/s 10.1128/aac.01062-07
Klebsiella Klebsiella MBC 0.14 ug ml-1 10.1021/jm00388a003
Klebsiella Klebsiella MIC 0.008 ug.mL-1 10.1021/jm00066a006
Klebsiella Klebsiella MIC 0.008 ug.mL-1 10.1021/jm00131a005
Klebsiella Klebsiella MIC 0.12 ug.mL-1 10.1021/jm00388a003
Klebsiella Klebsiella MIC 2.0 ug.mL-1 10.1021/jm00131a005
Klebsiella aerogenes Klebsiella aerogenes Activity 48.0 % 10.1128/aac.00426-09
Klebsiella aerogenes Klebsiella aerogenes Activity 79.0 % 10.1128/aac.01808-09
Klebsiella aerogenes Klebsiella aerogenes Lysis diameter 15.0 mm 10.1021/jm049652e
Klebsiella aerogenes Klebsiella aerogenes Lysis diameter 17.0 mm 10.1021/jm049652e
Klebsiella aerogenes Klebsiella aerogenes Lysis diameter 18.0 mm 10.1021/jm049652e
Klebsiella aerogenes Klebsiella aerogenes Lysis diameter 23.0 mm 10.1021/jm049652e
Klebsiella aerogenes Klebsiella aerogenes MIC 0.025 ug.mL-1 10.1016/s0960-894x(00)00130-x
Klebsiella aerogenes Klebsiella aerogenes MIC 0.06 ug.mL-1 10.1021/jm00107a035
Klebsiella aerogenes Klebsiella aerogenes MIC 0.2 ug.mL-1 10.1128/aac.01431-06
Klebsiella aerogenes Klebsiella aerogenes MIC 1.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella aerogenes Klebsiella aerogenes MIC 4.0 ug.mL-1 10.1021/jm00107a035
Klebsiella aerogenes Klebsiella aerogenes MIC 4.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella aerogenes Klebsiella aerogenes MIC 128.0 ug.mL-1 10.1128/aac.01028-07
Klebsiella aerogenes Klebsiella aerogenes MIC 128.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella aerogenes Klebsiella aerogenes MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella oxytoca Beta-lactamase Activity 2.3 % 10.1128/aac.00218-07
Klebsiella oxytoca Beta-lactamase Activity 13.0 % 10.1128/aac.00218-07
Klebsiella oxytoca Beta-lactamase Kcat 88.0 /s 10.1128/aac.00218-07
Klebsiella oxytoca Beta-lactamase Kcat/Km 0.16 /s/microM 10.1128/aac.00218-07
Klebsiella oxytoca Beta-lactamase Km 550000.0 nM 10.1128/aac.00218-07
Klebsiella oxytoca Klebsiella oxytoca Activity 14.0 % 10.1128/aac.00426-09
Klebsiella oxytoca Klebsiella oxytoca Activity 96.0 % 10.1128/aac.01808-09
Klebsiella oxytoca Klebsiella oxytoca Activity 97.0 % 10.1128/aac.00426-09
Klebsiella oxytoca Klebsiella oxytoca IZ 16.8 mm 10.1128/aac.00576-07
Klebsiella oxytoca Klebsiella oxytoca MIC 1.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella oxytoca Klebsiella oxytoca MIC 1.5 ug.mL-1 10.1128/aac.01473-08
Klebsiella oxytoca Klebsiella oxytoca MIC 1.563 ug.mL-1 10.1016/s0960-894x(00)00130-x
Klebsiella oxytoca Klebsiella oxytoca MIC 16.0 ug.mL-1 10.1128/aac.01473-08
Klebsiella oxytoca Klebsiella oxytoca MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Klebsiella oxytoca Klebsiella oxytoca MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Klebsiella pneumoniae Beta-lactamase AH27 CTX-M-15 Kcat 176.0 /s 10.1128/aac.00461-09
Klebsiella pneumoniae Beta-lactamase AH27 CTX-M-15 Km 26000.0 nM 10.1128/aac.00461-09
Klebsiella pneumoniae Beta-lactamase AH27 CTX-M-15 Ratio 6.77 None 10.1128/aac.00461-09
Klebsiella pneumoniae Beta-lactamase NDM-1 Kcat 6.0 /s 10.1128/aac.00774-09
Klebsiella pneumoniae Beta-lactamase NDM-1 Kcat/Km 0.58 /s/microM 10.1128/aac.00774-09
Klebsiella pneumoniae Beta-lactamase NDM-1 Km 10000.0 nM 10.1128/aac.00774-09
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat 0.1 /s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat 0.1 /s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat/Km nan None 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat/Km nan None 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Km 257000.0 nM 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Km nan None 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-55 Kcat 24.0 /s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-55 Kcat/Km 1.1 /uM/s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-55 Km 21000.0 nM 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-72 Kcat 0.1 /s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-72 Kcat/Km nan None 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-72 Km nan None 10.1128/aac.01381-07
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Kcat 14.0 /s 10.1128/aac.00491-07
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Kcat 142.0 /s 10.1128/aac.00197-10
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Kcat/Km 0.7 /uM/s 10.1128/aac.00197-10
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Kcat/Km 90.0 /mM/s 10.1128/aac.00491-07
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Km 160000.0 nM 10.1128/aac.00491-07
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Km 207000.0 nM 10.1128/aac.00197-10
Klebsiella pneumoniae Class C beta-lactamase CMY-36 Kcat 0.01 /s 10.1128/aac.01284-08
Klebsiella pneumoniae Class C beta-lactamase CMY-36 Km nan None 10.1128/aac.01284-08
Klebsiella pneumoniae Extended spectrum beta-lactamase CTX-M-71 Kcat 65.0 /s 10.1128/aac.00461-09
Klebsiella pneumoniae Extended spectrum beta-lactamase CTX-M-71 Km 130000.0 nM 10.1128/aac.00461-09
Klebsiella pneumoniae Extended spectrum beta-lactamase CTX-M-71 Ratio 0.5 None 10.1128/aac.00461-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.0 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.0 % 10.1128/aac.01509-06
Klebsiella pneumoniae Klebsiella pneumoniae Activity 0.0 % 10.1128/aac.01821-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 6.4 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 6.7 % 10.1128/aac.00762-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 9.0 % 10.1128/aac.00426-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 12.0 % 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity 14.5 % 10.1128/aac.00762-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 15.1 % 10.1128/aac.00762-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 19.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 38.1 % 10.1128/aac.01821-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 85.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 92.1 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 97.0 % 10.1128/aac.00426-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 99.0 % 10.1128/aac.01808-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity 100.0 % 10.1128/aac.00265-10
Klebsiella pneumoniae Klebsiella pneumoniae Activity 146.0 % 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae Activity nan None 10.1016/j.ejmech.2022.114571
Klebsiella pneumoniae Klebsiella pneumoniae ED50 3.8 mg.kg-1 10.1021/jm00388a003
Klebsiella pneumoniae Klebsiella pneumoniae ED50 45.0 mg.kg-1 10.1021/jm00029a012
Klebsiella pneumoniae Klebsiella pneumoniae Inhibition nan % 10.1128/aac.00471-08
Klebsiella pneumoniae Klebsiella pneumoniae IZ 10.8 mm 10.1128/aac.00576-07
Klebsiella pneumoniae Klebsiella pneumoniae IZ 11.0 mm 10.1128/aac.00877-08
Klebsiella pneumoniae Klebsiella pneumoniae IZ 13.0 mm 10.1016/j.ejmech.2006.09.023
Klebsiella pneumoniae Klebsiella pneumoniae IZ 13.0 mm 10.1016/j.ejmech.2007.01.011
Klebsiella pneumoniae Klebsiella pneumoniae IZ 13.0 mm 10.1016/j.ejmech.2008.02.038
Klebsiella pneumoniae Klebsiella pneumoniae IZ 13.0 mm 10.1016/j.ejmech.2009.07.003
Klebsiella pneumoniae Klebsiella pneumoniae IZ 13.0 mm 10.1128/aac.00167-07
Klebsiella pneumoniae Klebsiella pneumoniae IZ 16.0 mm 10.1128/aac.00877-08
Klebsiella pneumoniae Klebsiella pneumoniae IZ 18.0 mm 10.1128/aac.00877-08
Klebsiella pneumoniae Klebsiella pneumoniae IZ 21.4 mm 10.1016/j.bmc.2013.09.041
Klebsiella pneumoniae Klebsiella pneumoniae IZ 32.0 mm 10.1128/aac.00877-08
Klebsiella pneumoniae Klebsiella pneumoniae IZ nan None 10.1016/j.bmcl.2006.05.021
Klebsiella pneumoniae Klebsiella pneumoniae LD50 45.0 None 10.1021/jm00029a012
Klebsiella pneumoniae Klebsiella pneumoniae log10cfu 8.54 None 10.1128/aac.00471-08
Klebsiella pneumoniae Klebsiella pneumoniae MBC 25.0 mg/L 10.1007/s00044-011-9933-5
Klebsiella pneumoniae Klebsiella pneumoniae MBC 51.8 mg/L 10.1007/s00044-011-9933-5
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6e-05 ug.mL-1 10.1128/aac.00471-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.008 ug.mL-1 10.1021/jm00170a011
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.023 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.031 ug.mL-1 10.1021/jm00029a012
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.031 ug.mL-1 10.1021/jm00106a031
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.031 ug.mL-1 10.1021/jm00113a026
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.032 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.032 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.047 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.047 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.047 ug.mL-1 10.1128/aac.01473-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.05 ug.mL-1 10.1128/aac.00657-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1016/0960-894X(95)00090-G
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1016/s0960-894x(01)00587-x
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1021/jm00107a035
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01381-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.064 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.08 ug.mL-1 10.1128/aac.00657-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.094 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.094 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.1 ug.mL-1 10.1128/aac.00387-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.00543-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01198-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01381-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.13 ug.mL-1 10.1021/jm00388a003
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.19 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.47 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1016/j.bmc.2013.09.041
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00359-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01198-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.94 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1021/jm00170a011
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01473-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1.5 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1016/j.ejmech.2022.114571
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00010-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00461-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 3.0 ug.mL-1 10.1128/aac.00359-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00017-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00359-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00841-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01672-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.0 ug.mL-1 10.1128/aac.00359-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.0 ug.mL-1 10.1128/aac.01473-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00359-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00690-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00909-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 10.25 ug.mL-1 10.1021/jm980476h
Klebsiella pneumoniae Klebsiella pneumoniae MIC 12.0 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00197-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00359-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00693-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00841-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01198-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01451-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01534-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/j.ejmech.2019.02.024
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00167-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00882-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01180-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01284-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01301-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01451-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 48.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 48.0 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00461-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00543-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00841-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00886-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01198-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01431-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 96.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00011-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00017-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00436-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00841-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00886-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.01539-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00017-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00690-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00736-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00774-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.00830-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01053-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01099-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01198-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01440-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01534-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01539-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01607-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.00458-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.01198-10
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.01312-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512.0 ug.mL-1 10.1128/aac.01672-07
Klebsiella pneumoniae Klebsiella pneumoniae MIC 1700.0 nM 10.1021/acs.jnatprod.6b00011
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8000.0 nM 10.1021/acs.jmedchem.1c00614
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16000.0 ug.mL-1 10.1016/j.bmc.2021.116128
Klebsiella pneumoniae Klebsiella pneumoniae MIC 134000.0 nM 10.1021/jm300820a
Klebsiella pneumoniae Klebsiella pneumoniae MIC nan None 10.1128/aac.00657-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.023 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.047 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.094 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.00762-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 0.125 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01821-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01509-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 16.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 64.0 ug.mL-1 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 64.0 ug.mL-1 10.1128/aac.01821-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 128.0 ug.mL-1 10.1128/aac.00171-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC50 256.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 0.094 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 0.125 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 0.19 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01821-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00883-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.00852-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 128.0 ug.mL-1 10.1128/aac.00171-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 128.0 ug.mL-1 10.1128/aac.00762-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 256.0 ug.mL-1 10.1128/aac.00171-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 256.0 ug.mL-1 10.1128/aac.00746-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 256.0 ug.mL-1 10.1128/aac.01509-06
Klebsiella pneumoniae Klebsiella pneumoniae MIC90 512.0 ug.mL-1 10.1128/aac.01821-09
Klebsiella pneumoniae Metallo-beta-lactamase VIM-2 Kcat 28.0 /s 10.1128/aac.00774-09
Klebsiella pneumoniae Metallo-beta-lactamase VIM-2 Kcat/Km 0.86 /s/microM 10.1128/aac.00774-09
Klebsiella pneumoniae Metallo-beta-lactamase VIM-2 Km 32000.0 nM 10.1128/aac.00774-09
Lactococcus lactis Lactococcus lactis IZ 30.0 mm 10.1016/j.bmcl.2016.03.117
Lactococcus lactis Lactococcus lactis MIC 12.0 ug.mL-1 10.1016/j.bmcl.2016.03.117
Listeria monocytogenes Listeria monocytogenes FC 2.0 None 10.1128/aac.00290-10
Listeria monocytogenes Listeria monocytogenes FC 2.0 None 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes IZ 16.0 mm 10.1016/j.ejmech.2006.09.023
Listeria monocytogenes Listeria monocytogenes IZ 16.0 mm 10.1016/j.ejmech.2007.01.011
Listeria monocytogenes Listeria monocytogenes IZ 16.0 mm 10.1016/j.ejmech.2008.02.038
Listeria monocytogenes Listeria monocytogenes IZ 16.0 mm 10.1016/j.ejmech.2009.07.003
Listeria monocytogenes Listeria monocytogenes IZ 19.6 mm 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes IZ 21.3 mm 10.1128/aac.00290-10
Listeria monocytogenes Listeria monocytogenes IZ 22.5 mm 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes IZ 23.7 mm 10.1128/aac.00290-10
Listeria monocytogenes Listeria monocytogenes MIC 1.0 ug.mL-1 10.1128/aac.00290-10
Listeria monocytogenes Listeria monocytogenes MIC 1.0 ug.mL-1 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes MIC 2.0 ug.mL-1 10.1128/aac.00290-10
Listeria monocytogenes Listeria monocytogenes MIC 2.0 ug.mL-1 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes MIC 2.0 ug.mL-1 10.1128/aac.01569-09
Listeria monocytogenes Listeria monocytogenes MIC50 32.0 ug.mL-1 10.1128/aac.01569-09
Listeria monocytogenes Listeria monocytogenes MIC90 32.0 ug.mL-1 10.1128/aac.01569-09
Micrococcus luteus Micrococcus luteus IZ 11.0 mm 10.1016/j.ejmech.2020.112832
Micrococcus luteus Micrococcus luteus IZ 18.0 mm 10.1016/j.ejmech.2009.07.003
Micrococcus luteus Micrococcus luteus IZ 32.0 mm 10.1016/j.ejmech.2006.09.023
Micrococcus luteus Micrococcus luteus IZ 32.0 mm 10.1016/j.ejmech.2007.01.011
Micrococcus luteus Micrococcus luteus IZ 54.0 mm 10.1016/j.ejmech.2008.02.038
Micrococcus luteus Micrococcus luteus MIC 0.031 ug.mL-1 10.1021/jm00029a012
Micrococcus luteus Micrococcus luteus MIC 0.031 ug.mL-1 10.1021/jm00113a026
Micrococcus luteus Micrococcus luteus MIC 3.0 ug.mL-1 10.1128/aac.01436-08
Moraxella catarrhalis Moraxella catarrhalis MIC 0.03 ug.mL-1 10.1128/aac.01569-09
Moraxella catarrhalis Moraxella catarrhalis MIC 0.25 ug.mL-1 10.1016/0960-894X(95)00090-G
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.25 ug.mL-1 10.1128/aac.01569-09
Moraxella catarrhalis Moraxella catarrhalis MIC90 1.0 ug.mL-1 10.1128/aac.01569-09
Morganella morganii Morganella morganii MIC 0.25 ug.mL-1 10.1021/jm00131a005
Morganella morganii Morganella morganii MIC 2.0 ug.mL-1 10.1016/0960-894X(95)00090-G
Morganella morganii Morganella morganii MIC 16.0 ug.mL-1 10.1128/aac.01431-06
Morganella morganii Morganella morganii MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Mus musculus Mus musculus ED50 3.0 mg.kg-1 10.1016/0960-894X(95)00485-C
Mus musculus Mus musculus ED50 4.6 mg.kg-1 10.1016/0960-894X(95)00485-C
Mus musculus Mus musculus ED50 15.0 mg.kg-1 10.1021/jm00113a026
Mus musculus Mus musculus ED50 100.0 mg.kg-1 10.1021/jm00113a026
Mus musculus Mus musculus ED50 nan mg.kg-1 10.1016/0960-894X(95)00485-C
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mus musculus Solute carrier family 22 member 6 Inhibition nan % 10.1124/dmd.112.049569
Mus musculus Solute carrier family 22 member 8 Inhibition nan % 10.1124/dmd.112.049569
Mus musculus Solute carrier family 22 member 8 PPB nan % 10.1124/dmd.112.049569
Mycobacterium Mycobacterium IZ 0.0 mm 10.1016/j.bmcl.2006.05.021
Mycolicibacterium smegmatis Mycolicibacterium smegmatis IZ 11.0 mm 10.1016/j.ejmech.2006.09.023
Mycolicibacterium smegmatis Mycolicibacterium smegmatis IZ 11.0 mm 10.1016/j.ejmech.2007.01.011
Mycolicibacterium smegmatis Mycolicibacterium smegmatis IZ 11.0 mm 10.1016/j.ejmech.2008.02.038
Mycolicibacterium smegmatis Mycolicibacterium smegmatis IZ 11.0 mm 10.1016/j.ejmech.2009.07.003
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 40.0 ug.mL-1 10.1021/np900047p
Neisseria meningitidis Neisseria meningitidis MIC 0.012 ug.mL-1 10.1128/aac.00914-07
Neisseria perflava Neisseria perflava MBC 0.09 ug ml-1 10.1021/jm00388a003
Neisseria perflava Neisseria perflava MIC 0.09 ug.mL-1 10.1021/jm00388a003
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Parabacteroides distasonis Parabacteroides distasonis MIC 2.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Pasteurella multocida Pasteurella multocida MIC 0.06 ug.mL-1 10.1128/aac.01522-08
Pasteurella multocida Pasteurella multocida MIC 0.5 ug.mL-1 10.1128/aac.01522-08
Pasteurella multocida Pasteurella multocida MIC 1.0 ug.mL-1 10.1128/aac.01522-08
Pasteurella sp. Pasteurella sp. Activity 8.0 % 10.1128/aac.01808-09
Pectobacterium atrosepticum Pectobacterium atrosepticum MIC 1.0 ug.mL-1 10.1128/aac.01062-07
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 0.25 ug.mL-1 10.1016/S0960-894X(01)80927-6
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.25 ug.mL-1 10.1016/S0960-894X(01)80927-6
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.5 ug.mL-1 10.1016/S0960-894X(01)80927-6
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 16.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 32.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Phocaeicola vulgatus Phocaeicola vulgatus MIC 2.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Prevotella melaninogenica Prevotella melaninogenica MIC 2.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Primula vulgaris Primula vulgaris MIC 0.5 ug.mL-1 10.1021/jm00107a035
Proteus Proteus MBC 0.3 ug ml-1 10.1021/jm00388a003
Proteus Proteus MIC 0.08 ug.mL-1 10.1021/jm00388a003
Proteus mirabilis Proteus mirabilis Activity 0.0 % 10.1128/aac.01509-06
Proteus mirabilis Proteus mirabilis Activity 77.0 % 10.1128/aac.00426-09
Proteus mirabilis Proteus mirabilis Activity 100.0 % 10.1128/aac.01808-09
Proteus mirabilis Proteus mirabilis MIC 0.016 ug.mL-1 10.1021/jm00029a012
Proteus mirabilis Proteus mirabilis MIC 0.016 ug.mL-1 10.1021/jm00113a026
Proteus mirabilis Proteus mirabilis MIC 0.016 ug.mL-1 10.1021/jm00163a013
Proteus mirabilis Proteus mirabilis MIC 0.03 ug.mL-1 10.1016/0960-894X(95)00090-G
Proteus mirabilis Proteus mirabilis MIC 0.06 ug.mL-1 10.1021/jm00107a035
Proteus mirabilis Proteus mirabilis MIC 0.06 ug.mL-1 10.1128/aac.01400-08
Proteus mirabilis Proteus mirabilis MIC 0.25 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC 0.5 ug.mL-1 10.1128/aac.01431-06
Proteus mirabilis Proteus mirabilis MIC 2.0 ug.mL-1 10.1128/aac.01431-06
Proteus mirabilis Proteus mirabilis MIC 8.0 ug.mL-1 10.1128/aac.00111-10
Proteus mirabilis Proteus mirabilis MIC 8.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC 16.0 ug.mL-1 10.1128/aac.00111-10
Proteus mirabilis Proteus mirabilis MIC 16.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC 32.0 ug.mL-1 10.1128/aac.01399-07
Proteus mirabilis Proteus mirabilis MIC 40.0 ug.mL-1 10.1021/np900047p
Proteus mirabilis Proteus mirabilis MIC50 16.0 ug.mL-1 10.1128/aac.01509-06
Proteus mirabilis Proteus mirabilis MIC50 32.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC90 32.0 ug.mL-1 10.1128/aac.00883-08
Proteus mirabilis Proteus mirabilis MIC90 256.0 ug.mL-1 10.1128/aac.01509-06
Proteus vulgaris Proteus vulgaris IZ 14.0 mm 10.1016/j.ejmech.2009.07.003
Proteus vulgaris Proteus vulgaris IZ 18.0 mm 10.1016/j.ejmech.2006.09.023
Proteus vulgaris Proteus vulgaris IZ 18.0 mm 10.1016/j.ejmech.2007.01.011
Proteus vulgaris Proteus vulgaris IZ 32.0 mm 10.1016/j.ejmech.2008.02.038
Proteus vulgaris Proteus vulgaris MIC 16.0 ug.mL-1 10.1021/jm00163a013
Proteus vulgaris Proteus vulgaris MIC 32.0 ug.mL-1 10.1128/aac.00274-09
Proteus vulgaris Proteus vulgaris MIC 128.0 ug.mL-1 10.1021/jm00029a012
Proteus vulgaris Proteus vulgaris MIC 128.0 ug.mL-1 10.1021/jm00113a026
Providencia rettgeri Providencia rettgeri MIC 0.125 ug.mL-1 10.1021/jm00131a005
Providencia rettgeri Providencia rettgeri MIC 64.0 ug.mL-1 10.1128/aac.01312-09
Providencia stuartii Providencia stuartii MIC 2.0 ug.mL-1 10.1128/aac.00017-09
Providencia stuartii Providencia stuartii MIC 32.0 ug.mL-1 10.1128/aac.00274-09
Providencia stuartii Providencia stuartii MIC 128.0 ug.mL-1 10.1128/aac.00017-09
Pseudomonas Pseudomonas MBC 22.27 ug ml-1 10.1021/jm00388a003
Pseudomonas Pseudomonas MIC 21.82 ug.mL-1 10.1021/jm00388a003
Pseudomonas aeruginosa Beta-lactamase Kcat 0.1 /s 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase Kcat 0.13 /s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase Kcat/Km 20.0 /uM/s 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase Kcat/Km 290.0 /mM/s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase Km 450.0 nM 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase Km 5000.0 nM 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase bla(BEL1) Kcat 30.0 /s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase bla(BEL1) Kcat/Km 250.0 /mM/s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase bla(BEL1) Km 250000.0 nM 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase GES-13 Kcat 69.0 /s 10.1128/aac.01561-09
Pseudomonas aeruginosa Beta-lactamase GES-13 Kcat/Km 1.09 /uM/s 10.1128/aac.01561-09
Pseudomonas aeruginosa Beta-lactamase GES-13 Km 63000.0 nM 10.1128/aac.01561-09
Pseudomonas aeruginosa Beta-lactamase VIM-1 Kcat 204.0 /s 10.1128/aac.00465-08
Pseudomonas aeruginosa Beta-lactamase VIM-1 Kcat/Km 7.18 /M/s 10.1128/aac.00465-08
Pseudomonas aeruginosa Beta-lactamase VIM-1 Km 285000.0 nM 10.1128/aac.00465-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Activity nan None 10.1128/aac.00175-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat 70.0 /s 10.1128/aac.00166-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat nan None 10.1128/aac.00175-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat/Km 5.8 /uM/s 10.1128/aac.00166-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat/Km nan None 10.1128/aac.00175-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Km 12000.0 nM 10.1128/aac.00166-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Km nan None 10.1128/aac.00175-08
Pseudomonas aeruginosa Class B carbapenemase VIM-13 Kcat 612.0 /s 10.1128/aac.00465-08
Pseudomonas aeruginosa Class B carbapenemase VIM-13 Kcat/Km 2.6 /M/s 10.1128/aac.00465-08
Pseudomonas aeruginosa Class B carbapenemase VIM-13 Km 233000.0 nM 10.1128/aac.00465-08
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-11 Kcat 41.3 /s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-11 Kcat/Km 3.6 10'6/M/s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-11 Km 11400.0 nM 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-2 Kcat 61.0 /s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-2 Kcat/Km 4.6 10'6/M/s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-2 Km 13400.0 nM 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-b-lactamase Kcat 56.0 /s 10.1128/aac.00166-08
Pseudomonas aeruginosa Metallo-b-lactamase Kcat/Km 2.6 /uM/s 10.1128/aac.00166-08
Pseudomonas aeruginosa Metallo-b-lactamase Km 22000.0 nM 10.1128/aac.00166-08
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 9.0 % 10.1128/aac.01808-09
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 14.0 % 10.1128/aac.00426-09
Pseudomonas aeruginosa Pseudomonas aeruginosa ED50 250.0 mg.kg-1 10.1021/jm00106a031
Pseudomonas aeruginosa Pseudomonas aeruginosa FICI 0.14 None 10.1128/aac.01071-07
Pseudomonas aeruginosa Pseudomonas aeruginosa IC50 30.0 nM 10.1021/acs.jnatprod.9b00187
Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition 10.0 % 10.1128/aac.00471-08
Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition nan % 10.1128/aac.00471-08
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 10.4 mm 10.1016/j.bmc.2013.09.041
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 11.0 mm 10.1016/j.ejmech.2020.112832
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 14.0 mm 10.1016/j.ejmech.2008.02.038
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 18.0 mm 10.1016/j.bmcl.2016.03.117
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 32.0 mm 10.1016/j.ejmech.2009.07.003
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 54.0 mm 10.1016/j.ejmech.2006.09.023
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 54.0 mm 10.1016/j.ejmech.2007.01.011
Pseudomonas aeruginosa Pseudomonas aeruginosa LD50 250.0 None 10.1021/jm00029a012
Pseudomonas aeruginosa Pseudomonas aeruginosa log10cfu 8.68 None 10.1128/aac.00471-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 16.3 mg/L 10.1007/s00044-011-9933-5
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 81.2 mg/L 10.1007/s00044-011-9933-5
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.064 ug.mL-1 10.1128/aac.00471-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.098 ug.mL-1 10.1016/s0960-894x(00)00130-x
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.19 ug.mL-1 10.1128/aac.01451-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1128/aac.01451-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.125 ug.mL-1 10.1016/s0960-894x(00)00130-x
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00009-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1021/jm00066a006
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8.0 ug.mL-1 10.1128/aac.00009-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 10.0 ug.mL-1 10.1016/j.bmcl.2016.03.117
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/s0960-894x(00)00130-x
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1128/aac.01436-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/0960-894X(95)00090-G
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/s0960-894x(01)00587-x
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1021/jm00029a012
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1021/jm00066a006
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1021/jm00113a026
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00009-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00110-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00465-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1128/aac.00899-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 25.0 ug.mL-1 10.1016/0960-894X(95)00485-C
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 25.0 ug.mL-1 10.1016/s0960-894x(00)00130-x
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1021/jm00131a005
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1021/jm00170a011
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.00859-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.01451-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1128/aac.01602-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 40.0 ug.mL-1 10.1021/np900047p
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 62.35 ug.mL-1 10.1021/jm980476h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1021/jm00106a031
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1021/jm00163a013
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1021/jm00170a011
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00009-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00110-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 69.86 ug.mL-1 10.1021/jm960810e
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 120.0 ug.mL-1 10.1128/aac.01071-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm00029a012
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm00107a035
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm00113a026
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm00163a013
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.00009-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.00110-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 135.0 ug.mL-1 10.1021/jm960810e
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00009-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00110-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00175-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00465-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00816-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00859-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.01405-06
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.01573-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 400.0 nM 10.1021/acs.jnatprod.6b00011
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1128/aac.00009-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1128/aac.00110-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 960.0 ug.mL-1 10.1128/aac.01071-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1000.0 nM 10.1021/acs.jmedchem.1c00614
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16000.0 ug.mL-1 10.1016/j.bmc.2021.116128
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1128/aac.00734-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1128/aac.01011-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1128/aac.01561-09
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC80 nan None 10.1016/j.ejmech.2012.05.013
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat 0.02 /s 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat/Km 3.0 /uM/s 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Km 6000.0 nM 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase MPC 1.03 ug ml-1 10.1021/jm960810e
Pseudomonas fluorescens Beta-lactamase Kcat/Km 9.0 /mM/s 10.1128/aac.00961-09
Pseudomonas fluorescens Pseudomonas fluorescens Activity 8.0 % 10.1128/aac.01808-09
Pseudomonas fluorescens Pseudomonas fluorescens MIC 32.0 ug.mL-1 10.1128/aac.00961-09
Pseudomonas luteola Beta-lactamase Kcat 452.0 /s 10.1128/aac.00427-09
Pseudomonas luteola Beta-lactamase Kcat/Km 5.25 /s/microM 10.1128/aac.00427-09
Pseudomonas luteola Beta-lactamase Km 86000.0 nM 10.1128/aac.00427-09
Pseudomonas stutzeri Metallo-beta-lactamase Kcat 10.0 /s 10.1128/aac.01456-09
Pseudomonas stutzeri Metallo-beta-lactamase Km 3500.0 nM 10.1128/aac.01456-09
Pseudomonas stutzeri Metallo-beta-lactamase Ratio 3000.0 None 10.1128/aac.01456-09
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Brain Vdu nan None 10.1021/jm901036q
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Oligopeptide transporter, kidney isoform Ki 20000000.0 nM 10.1016/j.ejpb.2004.07.008
Rattus norvegicus Plasma Cp(f) 2.8 uM 10.1021/jm901036q
Rattus norvegicus Plasma Fu 0.59 None 10.1021/jm901036q
Rattus norvegicus Plasma K(p,uu,CSF) 0.007 None 10.1021/jm901036q
Rattus norvegicus Plasma logFu 0.6 None 10.1016/j.ejmech.2009.06.004
Rattus norvegicus Rattus norvegicus ALB 40000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 41700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 44000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 325.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 343.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 354.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 407.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 52.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 55.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 57.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 62.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 70.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 70.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 90.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 90.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Bound 88.5 % 10.1021/jm00066a006
Rattus norvegicus Rattus norvegicus BUN 156.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 166.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 176.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 190.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 102.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 103.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 104.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 703.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 736.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 853.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 863.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 225.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 235.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 330.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 349.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 23000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 23670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 25670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 29330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 4.9 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 63.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 92.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1530.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1633.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1673.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 32.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 35.7 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 37.4 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 38.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 123300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 134300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 138700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 140000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 77.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 138.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 139.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 186.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 12.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 10640.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11282.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11544.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13558.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 75.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 88.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 90.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 93.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.2 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.53 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.8 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.93 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 357300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 374700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 376300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 377700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.63 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.47 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.57 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 65.93 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 57.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 120.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 213.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 820.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 4.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 6.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 11.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 19.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 730.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1075.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1309.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 3591.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 117.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 118.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 121.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 141.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1107670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1231670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1356670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1367000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.32 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.42 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.59 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 7.29 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 58000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 63000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 64300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5160000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5790000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5880000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5890000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.33 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 145.77 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 146.03 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 146.17 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 146.77 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus T1/2 0.25 hr 10.1016/0960-894X(95)00090-G
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 16.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 17.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 20.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 21.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 12100.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 12130.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 12830.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 18030.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Solute carrier family 22 member 6 Activity nan None None
Rattus norvegicus Solute carrier family 22 member 6 IC50 2000000.0 nM 10.1016/s0024-3205(02)01500-x
Rattus norvegicus Solute carrier family 22 member 7 IC50 5000000.0 nM 10.1016/s0014-2999(03)01381-5
Rattus norvegicus Solute carrier family 22 member 8 IC50 800000.0 nM 10.1016/s0024-3205(02)01500-x
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Potency 794.3 nM None
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Potency 13371.4 nM None
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Potency 23778.1 nM None
Salmonella Salmonella MBC 0.38 ug ml-1 10.1021/jm00388a003
Salmonella Salmonella MIC 0.03 ug.mL-1 10.1021/jm00131a005
Salmonella Salmonella MIC 0.24 ug.mL-1 10.1021/jm00388a003
Salmonella Salmonella MIC 40.0 ug.mL-1 10.1021/np900047p
Salmonella enterica Salmonella enterica IZ nan None 10.1016/j.bmcl.2006.05.021
Salmonella enterica Salmonella enterica MIC 8.0 ug.mL-1 10.1128/aac.00310-09
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 0.125 ug.mL-1 10.1128/aac.00225-10
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 20.3 ug.mL-1 10.1021/jm980476h
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 128.0 ug.mL-1 10.1128/aac.00225-10
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.025 ug.mL-1 10.1016/s0960-894x(00)00130-x
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC nan None 10.1128/aac.01472-06
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Ratio 4.0 None 10.1016/j.ejmech.2012.03.008
Salmonella enterica subsp. enterica serovar Westhampton Extended-spectrum beta-lactamase CTX-M-53 Kcat 585.0 /s 10.1128/aac.01581-08
Salmonella enterica subsp. enterica serovar Westhampton Extended-spectrum beta-lactamase CTX-M-53 Kcat/Km 3.2 /s/microM 10.1128/aac.01581-08
Salmonella enterica subsp. enterica serovar Westhampton Extended-spectrum beta-lactamase CTX-M-53 Km 180000.0 nM 10.1128/aac.01581-08
Salmonella newport Efflux transporter Kcat 0.01 /s 10.1128/aac.01284-08
Salmonella newport Efflux transporter Km nan None 10.1128/aac.01284-08
Sarcina Sarcina MBC 0.04 ug ml-1 10.1021/jm00388a003
Sarcina Sarcina MIC 0.04 ug.mL-1 10.1021/jm00388a003
Serratia Serratia MBC 0.49 ug ml-1 10.1021/jm00388a003
Serratia Serratia MIC 0.09 ug.mL-1 10.1021/jm00388a003
Serratia fonticola Carbapenem-hydrolizing beta-lactamase SFC-1 Kcat 8.3 /s 10.1128/aac.00491-07
Serratia fonticola Carbapenem-hydrolizing beta-lactamase SFC-1 Kcat/Km 93.3 /mM/s 10.1128/aac.00491-07
Serratia fonticola Carbapenem-hydrolizing beta-lactamase SFC-1 Km 89000.0 nM 10.1128/aac.00491-07
Serratia marcescens Serratia marcescens Activity 100.0 % 10.1128/aac.01808-09
Serratia marcescens Serratia marcescens ED50 25.0 mg.kg-1 10.1021/jm00029a012
Serratia marcescens Serratia marcescens ED50 50.0 mg.kg-1 10.1021/jm00106a031
Serratia marcescens Serratia marcescens ED50 250.0 mg.kg-1 10.1021/jm00029a012
Serratia marcescens Serratia marcescens LD50 25.0 None 10.1021/jm00029a012
Serratia marcescens Serratia marcescens MIC 0.25 ug.mL-1 10.1021/jm00106a031
Serratia marcescens Serratia marcescens MIC 0.25 ug.mL-1 10.1021/jm00107a035
Serratia marcescens Serratia marcescens MIC 0.25 ug.mL-1 10.1021/jm00170a011
Serratia marcescens Serratia marcescens MIC 8.0 ug.mL-1 10.1021/jm00163a013
Serratia marcescens Serratia marcescens MIC 16.0 ug.mL-1 10.1128/aac.01539-07
Serratia marcescens Serratia marcescens MIC 16.0 ug.mL-1 10.1128/aac.01634-07
Serratia marcescens Serratia marcescens MIC 32.0 ug.mL-1 10.1021/jm00029a012
Serratia marcescens Serratia marcescens MIC 32.0 ug.mL-1 10.1021/jm00113a026
Serratia marcescens Serratia marcescens MIC 32.0 ug.mL-1 10.1128/aac.00768-10
Serratia marcescens Serratia marcescens MIC 32.0 ug.mL-1 10.1128/aac.01634-07
Serratia marcescens Serratia marcescens MIC 128.0 ug.mL-1 10.1128/aac.01028-07
Serratia marcescens Serratia marcescens MIC 256.0 ug.mL-1 10.1128/aac.00768-10
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 4.74 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.11 % 10.6019/CHEMBL4495565
Shigella Shigella MIC 0.06 ug.mL-1 10.1128/aac.00039-10
Shigella Shigella MIC 32.0 ug.mL-1 10.1128/aac.00039-10
Shigella Shigella MIC 64.0 ug.mL-1 10.1128/aac.00039-10
Shigella Shigella MIC 128.0 ug.mL-1 10.1128/aac.00039-10
Shigella flexneri Shigella flexneri MIC 8.0 ug.mL-1 10.1128/aac.00039-10
Shigella flexneri Shigella flexneri MIC 32.0 ug.mL-1 10.1128/aac.00039-10
Shigella sonnei Shigella sonnei MIC 0.12 ug.mL-1 10.1128/aac.00227-08
Shigella sonnei Shigella sonnei MIC 64.0 ug.mL-1 10.1128/aac.00039-10
Shigella sonnei Shigella sonnei MIC 1024.0 ug.mL-1 10.1128/aac.00227-08
Shouchella clausii Shouchella clausii Activity nan None 10.1128/aac.00537-07
Shouchella clausii Shouchella clausii MIC 16000.0 ug.mL-1 10.1128/aac.00537-07
Staphylococcus Staphylococcus MBC 3.23 ug ml-1 10.1021/jm00388a003
Staphylococcus Staphylococcus MBC 25.0 ug ml-1 10.1021/jm00388a003
Staphylococcus Staphylococcus MIC 1.61 ug.mL-1 10.1021/jm00388a003
Staphylococcus Staphylococcus MIC 5.25 ug.mL-1 10.1021/jm00388a003
Staphylococcus Staphylococcus MIC 100.0 ug.mL-1 10.1128/aac.01436-08
Staphylococcus aureus Beta-lactamase MPC 2.72 ug ml-1 10.1021/jm960810e
Staphylococcus aureus MecA IC50 0.25 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus MecA IC50 1.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus MecA IC50 2.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus MecA IC50 128.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Penicillin-binding protein 2b Binding affinity 0.1 None 10.1021/jm00029a012
Staphylococcus aureus Staphylococcus aureus Activity 50.0 % 10.1021/acs.jmedchem.8b01433
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.ejmech.2014.03.033
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.01436-08
Staphylococcus aureus Staphylococcus aureus ED50 6.0 mg.kg-1 10.1021/jm00029a012
Staphylococcus aureus Staphylococcus aureus IC50 30.0 nM 10.1021/acs.jnatprod.9b00187
Staphylococcus aureus Staphylococcus aureus Inhibition nan % 10.1128/aac.00471-08
Staphylococcus aureus Staphylococcus aureus IZ 0.0 mm 10.1016/j.bmcl.2006.05.021
Staphylococcus aureus Staphylococcus aureus IZ 11.0 mm 10.1016/j.ejmech.2020.112832
Staphylococcus aureus Staphylococcus aureus IZ 12.0 mm 10.1016/j.ejmech.2006.09.023
Staphylococcus aureus Staphylococcus aureus IZ 12.0 mm 10.1016/j.ejmech.2007.01.011
Staphylococcus aureus Staphylococcus aureus IZ 12.0 mm 10.1016/j.ejmech.2008.02.038
Staphylococcus aureus Staphylococcus aureus IZ 12.0 mm 10.1016/j.ejmech.2009.07.003
Staphylococcus aureus Staphylococcus aureus IZ 21.7 mm 10.1016/j.bmc.2013.09.041
Staphylococcus aureus Staphylococcus aureus IZ 26.0 mm 10.1016/j.bmcl.2006.05.021
Staphylococcus aureus Staphylococcus aureus IZ 31.0 mm 10.1016/j.bmcl.2016.03.117
Staphylococcus aureus Staphylococcus aureus IZ 35.0 mm 10.1016/j.ejmech.2014.03.033
Staphylococcus aureus Staphylococcus aureus LD50 6.0 None 10.1021/jm00029a012
Staphylococcus aureus Staphylococcus aureus log10cfu 9.67 None 10.1128/aac.00471-08
Staphylococcus aureus Staphylococcus aureus MBC 12.7 mg/L 10.1007/s00044-011-9933-5
Staphylococcus aureus Staphylococcus aureus MBC 77.2 mg/L 10.1007/s00044-011-9933-5
Staphylococcus aureus Staphylococcus aureus MIC 0.0038 ug.mL-1 10.1128/aac.00471-08
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1128/aac.01569-09
Staphylococcus aureus Staphylococcus aureus MIC 0.08 ug.mL-1 10.1021/jm980476h
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmc.2013.09.041
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 0.781 ug.mL-1 10.1016/s0960-894x(00)00130-x
Staphylococcus aureus Staphylococcus aureus MIC 0.781 ug.mL-1 10.1128/aac.00971-08
Staphylococcus aureus Staphylococcus aureus MIC 0.8 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2012.03.079
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2012.12.024
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/jm00106a031
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00971-08
Staphylococcus aureus Staphylococcus aureus MIC 1.25 ug.mL-1 10.1021/np900047p
Staphylococcus aureus Staphylococcus aureus MIC 1.56 ug.mL-1 10.1016/0960-894X(95)00485-C
Staphylococcus aureus Staphylococcus aureus MIC 1.563 ug.mL-1 10.1016/s0960-894x(00)00130-x
Staphylococcus aureus Staphylococcus aureus MIC 1.7 ug.mL-1 10.1021/jm960810e
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/0960-894X(95)00090-G
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm00029a012
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm00066a006
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm00113a026
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm00131a005
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm00163a013
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/jm00170a011
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00971-08
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus aureus Staphylococcus aureus MIC 3.0 ug.mL-1 10.1128/aac.01436-08
Staphylococcus aureus Staphylococcus aureus MIC 3.12 ug.mL-1 10.1016/j.ejmech.2011.05.028
Staphylococcus aureus Staphylococcus aureus MIC 3.12 ug.mL-1 10.1016/j.ejmech.2016.10.010
Staphylococcus aureus Staphylococcus aureus MIC 3.125 ug.mL-1 10.1016/s0960-894x(00)00130-x
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/0960-894X(95)00090-G
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2016.06.006
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm00107a035
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/jm00163a013
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00971-08
Staphylococcus aureus Staphylococcus aureus MIC 6.0 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1021/jm00066a006
Staphylococcus aureus Staphylococcus aureus MIC 15.0 ug.mL-1 10.1016/j.bmcl.2016.03.117
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1021/jm00170a011
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/0960-894X(95)00090-G
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/jm00107a035
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/jm00163a013
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 40.6 ug.mL-1 10.1021/jm960810e
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2012.03.079
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/jm00066a006
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1016/j.bmcl.2016.06.006
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/jm00029a012
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/jm00106a031
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/jm00113a026
Staphylococcus aureus Staphylococcus aureus MIC 130.0 ug.mL-1 10.1021/np500022w
Staphylococcus aureus Staphylococcus aureus MIC 200.0 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 261.0 nM 10.1007/s00044-010-9408-0
Staphylococcus aureus Staphylococcus aureus MIC 400.0 nM 10.1021/acs.jnatprod.6b00011
Staphylococcus aureus Staphylococcus aureus MIC 400.0 ug.mL-1 10.1128/aac.01436-08
Staphylococcus aureus Staphylococcus aureus MIC 800.0 ug.mL-1 10.1128/aac.01099-08
Staphylococcus aureus Staphylococcus aureus MIC 1024.0 ug.mL-1 10.1016/j.bmc.2021.116128
Staphylococcus aureus Staphylococcus aureus MIC 1024.0 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 2000.0 nM 10.1021/acs.jmedchem.1c00614
Staphylococcus aureus Staphylococcus aureus MIC 32900.0 nM 10.1016/j.ejmech.2017.08.066
Staphylococcus aureus Staphylococcus aureus MIC 34000.0 nM 10.1021/jm300820a
Staphylococcus aureus Staphylococcus aureus MIC 128000.0 nM 10.1021/jm401335p
Staphylococcus aureus Staphylococcus aureus MIC50 2.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus aureus Staphylococcus aureus MIC50 16.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus aureus Staphylococcus aureus MIC50 64.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus aureus Staphylococcus aureus MIC50 128.0 ug.mL-1 10.1016/j.ejmech.2012.12.024
Staphylococcus aureus Staphylococcus aureus MIC80 3.12 ug.mL-1 10.1016/j.ejmech.2011.04.053
Staphylococcus aureus Staphylococcus aureus MIC80 3.12 ug.mL-1 10.1016/j.ejmech.2012.05.013
Staphylococcus aureus Staphylococcus aureus MIC90 2.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus aureus Staphylococcus aureus MIC90 64.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus aureus Staphylococcus aureus MIC90 128.0 ug.mL-1 10.1016/j.ejmech.2012.12.024
Staphylococcus epidermidis Staphylococcus epidermidis MBC 75.0 mg/L 10.1007/s00044-011-9933-5
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.0 ug.mL-1 10.1016/0960-894X(95)00090-G
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1021/jm00066a006
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1021/jm00131a005
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.5 ug.mL-1 10.1021/np900047p
Staphylococcus epidermidis Staphylococcus epidermidis MIC 8.0 ug.mL-1 10.1021/jm00066a006
Staphylococcus epidermidis Staphylococcus epidermidis MIC 8.0 ug.mL-1 10.1128/aac.01436-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 12.5 ug.mL-1 10.1128/aac.01436-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2000.0 nM 10.1021/acs.jmedchem.1c00614
Staphylococcus saprophyticus Staphylococcus saprophyticus MBC 95.0 mg/L 10.1007/s00044-011-9933-5
Staphylococcus sp. Staphylococcus sp. MIC 0.015 ug.mL-1 10.1128/aac.01569-09
Staphylococcus sp. Staphylococcus sp. MIC 0.03 ug.mL-1 10.1128/aac.01569-09
Staphylococcus sp. Staphylococcus sp. MIC 0.5 ug.mL-1 10.1128/aac.01569-09
Staphylococcus sp. Staphylococcus sp. MIC50 0.03 ug.mL-1 10.1128/aac.01569-09
Staphylococcus sp. Staphylococcus sp. MIC50 0.5 ug.mL-1 10.1128/aac.01569-09
Staphylococcus sp. Staphylococcus sp. MIC50 4.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus sp. Staphylococcus sp. MIC50 8.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus sp. Staphylococcus sp. MIC90 1.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus sp. Staphylococcus sp. MIC90 2.0 ug.mL-1 10.1128/aac.01569-09
Staphylococcus sp. Staphylococcus sp. MIC90 64.0 ug.mL-1 10.1128/aac.01569-09
Stenotrophomonas maltophilia Beta-lactamase L1 Kcat/Km 2.6 10'6/M/s 10.1128/aac.01062-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity 8.0 % 10.1128/aac.01808-09
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity nan None 10.1128/aac.00682-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 4.0 ug.mL-1 10.1128/aac.01485-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 32.0 ug.mL-1 10.1016/j.bmc.2013.09.041
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 128.0 ug.mL-1 10.1128/aac.00682-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 256.0 ug.mL-1 10.1128/aac.00682-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC 1024.0 ug.mL-1 10.1128/aac.01485-07
Stenotrophomonas maltophilia Stenotrophomonas maltophilia Ratio 3.2 None 10.1128/aac.00682-07
Streptococcus Streptococcus MBC 35.36 ug ml-1 10.1021/jm00388a003
Streptococcus Streptococcus MIC 12.33 ug.mL-1 10.1021/jm00388a003
Streptococcus agalactiae Streptococcus agalactiae MIC 0.016 ug.mL-1 10.1016/j.bmc.2011.03.060
Streptococcus agalactiae Streptococcus agalactiae MIC 0.016 ug.mL-1 10.1128/aac.01716-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.06 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.12 ug.mL-1 10.1016/0960-894X(95)00090-G
Streptococcus agalactiae Streptococcus agalactiae MIC 0.12 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.25 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.5 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC 1.0 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC 2.0 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.031 ug.mL-1 10.1128/aac.01716-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.063 ug.mL-1 10.1128/aac.01716-08
Streptococcus mitis Streptococcus mitis MIC 0.016 ug.mL-1 10.1016/j.bmc.2011.03.060
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.2 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.8 % 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.0 ug ml-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.4 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 2.1 % 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 3.4 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 4.0 ug ml-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 4.4 % 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 5.9 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 6.9 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 17.7 % 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 25.0 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 41.1 % 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 49.7 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 58.5 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 62.4 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 62.7 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 77.0 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 78.7 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 80.7 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 93.1 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 93.8 % 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.6 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae ED50 69.0 mg.kg-1 10.1021/jm00029a012
Streptococcus pneumoniae Streptococcus pneumoniae ED50 90.0 mg.kg-1 10.1021/jm00106a031
Streptococcus pneumoniae Streptococcus pneumoniae LD50 69.0 None 10.1021/jm00029a012
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1021/jm00066a006
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1021/jm00131a005
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1021/jm00170a011
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1021/jm00029a012
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1021/jm00106a031
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1021/jm00113a026
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1021/jm00163a013
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.02 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.025 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/0960-894X(95)00090-G
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00185-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.035 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.04 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.045 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.055 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1016/j.bmc.2011.03.060
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.2 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.3 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmcl.2012.03.079
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01000-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1016/0960-894X(95)00090-G
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmcl.2012.03.079
Streptococcus pneumoniae Streptococcus pneumoniae MIC nan None 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.015 ug.mL-1 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.015 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.01 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01569-09
Streptococcus pneumoniae R6 Penicillin-binding protein 2X Activity nan None 10.1021/jm900625q
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.1 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.125 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.25 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 4.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 16.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 32.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x Activity nan None 10.1021/jm900625q
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.1 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.25 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 1.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 4.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pyogenes Streptococcus pyogenes Activity 0.0 % 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes Activity 0.0 % 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes ED50 5.2 mg.kg-1 10.1021/jm00163a013
Streptococcus pyogenes Streptococcus pyogenes ED50 7.0 mg.kg-1 10.1021/jm00106a031
Streptococcus pyogenes Streptococcus pyogenes Inhibition nan % 10.1128/aac.00471-08
Streptococcus pyogenes Streptococcus pyogenes log10cfu 8.2 None 10.1128/aac.00471-08
Streptococcus pyogenes Streptococcus pyogenes MIC 3e-05 ug.mL-1 10.1128/aac.00471-08
Streptococcus pyogenes Streptococcus pyogenes MIC 0.002 ug.mL-1 10.1016/s0960-894x(00)00130-x
Streptococcus pyogenes Streptococcus pyogenes MIC 0.007 ug.mL-1 10.1016/s0960-894x(00)00130-x
Streptococcus pyogenes Streptococcus pyogenes MIC 0.008 ug.mL-1 10.1021/jm00106a031
Streptococcus pyogenes Streptococcus pyogenes MIC 0.008 ug.mL-1 10.1021/jm00163a013
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1021/jm00131a005
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1021/jm00170a011
Streptococcus pyogenes Streptococcus pyogenes MIC 0.016 ug.mL-1 10.1016/j.bmc.2011.03.060
Streptococcus pyogenes Streptococcus pyogenes MIC 0.016 ug.mL-1 10.1021/jm00029a012
Streptococcus pyogenes Streptococcus pyogenes MIC 0.016 ug.mL-1 10.1021/jm00113a026
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1016/0960-894X(95)00090-G
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1021/jm00107a035
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC 100.0 ug.mL-1 10.1016/s0960-894x(00)00130-x
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.06 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.06 ug.mL-1 10.1128/aac.01536-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.015 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.03 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.06 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.06 ug.mL-1 10.1128/aac.00596-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.12 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.12 ug.mL-1 10.1128/aac.00596-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.25 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.5 ug.mL-1 10.1128/aac.00596-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 1.0 ug.mL-1 10.1128/aac.00596-08
Streptococcus viridans Streptococcus viridans MIC 0.015 ug.mL-1 10.1128/aac.01569-09
Streptococcus viridans Streptococcus viridans MIC50 0.12 ug.mL-1 10.1128/aac.01569-09
Streptococcus viridans Streptococcus viridans MIC90 0.5 ug.mL-1 10.1128/aac.01569-09
Streptomyces acidiscabies Streptomyces acidiscabies DIZ nan None 10.1584/jpestics.28.183
Streptomyces acidiscabies Streptomyces acidiscabies IZ 15.0 mm 10.1584/jpestics.28.183
Streptomyces alboniger Streptomyces alboniger DIZ nan None 10.1584/jpestics.28.183
Streptomyces scabiei Streptomyces scabiei DIZ nan None 10.1584/jpestics.28.183
Streptomyces scabiei Streptomyces scabiei IZ 22.0 mm 10.1584/jpestics.28.183
Stutzerimonas stutzeri Stutzerimonas stutzeri MIC 512.0 ug.mL-1 10.1128/aac.01456-09
Thomasclavelia ramosa Thomasclavelia ramosa MIC 2.0 ug.mL-1 10.1016/S0960-894X(01)80927-6
Trypanosoma brucei 6-phospho-1-fructokinase Potency 8492.1 nM None
Trypanosoma brucei brucei Phosphoglycerate kinase, glycosomal Potency 26854.5 nM None
Vibrio cholerae Vibrio cholerae MIC 523.0 nM 10.1007/s00044-010-9408-0
Yersinia enterocolitica Yersinia enterocolitica MIC 0.012 ug.mL-1 10.1128/aac.01754-09
Yersinia enterocolitica Yersinia enterocolitica MIC 0.016 ug.mL-1 10.1128/aac.01754-09
Yersinia enterocolitica Yersinia enterocolitica MIC 0.023 ug.mL-1 10.1128/aac.01754-09
None ADMET BPR nan None 10.1021/jm901036q
None ADMET CL 2.7 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET K(p,uu,brain) nan None 10.1021/jm901036q
None ADMET MRT 1.2 hr 10.1124/dmd.108.020479
None ADMET PPB 3.0 % 10.1128/aac.00971-08
None ADMET Ratio 1.0 None 10.1128/aac.00971-08
None ADMET RHR 100.0 None 10.1021/jm00369a001
None ADMET T1/2 0.5 hr 10.1021/jm00092a015
None ADMET T1/2 1.2 hr 10.1124/dmd.108.020479
None ADMET Vdss 0.19 L.kg-1 10.1124/dmd.108.020479
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value 0.3 None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 1.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 2.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value 4.7 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value 2.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None NON-PROTEIN TARGET Fu 0.6 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 3.3 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 33.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 33.3 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET MIC 0.016 ug.mL-1 10.1021/jm00029a012
None NON-PROTEIN TARGET MIC 0.016 ug.mL-1 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.016 ug.mL-1 10.1128/aac.00684-07
None NON-PROTEIN TARGET MIC 0.03 ug.mL-1 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.03 ug.mL-1 10.1128/aac.00242-07
None NON-PROTEIN TARGET MIC 0.032 ug.mL-1 10.1128/aac.00684-07
None NON-PROTEIN TARGET MIC 0.032 ug.mL-1 10.1128/aac.01252-09
None NON-PROTEIN TARGET MIC 0.032 ug.mL-1 10.1128/aac.01615-09
None NON-PROTEIN TARGET MIC 0.047 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.00242-07
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.00791-09
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.01152-06
None NON-PROTEIN TARGET MIC 0.12 ug.mL-1 10.1128/aac.00242-07
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00791-09
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00427-09
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.01581-08
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00427-09
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.01585-09
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.00899-09
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1016/j.bmc.2013.09.041
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.00899-09
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.01252-09
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.01284-08
None NON-PROTEIN TARGET MIC 32.0 ug.mL-1 10.1128/aac.01634-07
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.00734-08
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.01463-07
None NON-PROTEIN TARGET MIC 512.0 ug.mL-1 10.1128/aac.01600-06
None NON-PROTEIN TARGET MIC50 1.5 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC90 256.0 ug.mL-1 10.1128/aac.00630-09
None No relevant target pKa 3.75 None 10.1016/j.ejmech.2009.06.004
None No relevant target Stability 65.0 % 10.1016/j.bmc.2013.05.024
None Unchecked Activity 0.01 % 10.1128/aac.01164-08
None Unchecked Activity 1.0 None 10.1128/aac.01439-06
None Unchecked Activity 3.7 % 10.1128/aac.00083-07
None Unchecked Activity 7.8 % 10.1128/aac.00218-07
None Unchecked Activity 34.0 % 10.1128/aac.00218-07
None Unchecked Activity 47.0 % 10.1128/aac.00175-08
None Unchecked Activity 91.0 % 10.1128/aac.00175-08
None Unchecked Activity 300.0 % 10.1128/aac.00175-08
None Unchecked Activity 530.0 % 10.1128/aac.00175-08
None Unchecked Activity nan None 10.1128/aac.01145-07
None Unchecked Concentration 0.1 ug ml-1 10.1021/jm00106a031
None Unchecked FC 2.7 None 10.1128/aac.00197-10
None Unchecked FC 100.0 None 10.1128/aac.00537-07
None Unchecked Hepatotoxicity (acute) 4.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 2.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 0.1 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 0.25 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 0.5 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 1.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 2.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 4.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 8.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 16.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 128.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 nan None 10.1128/aac.00019-10
None Unchecked IC50 nan None None
None Unchecked Inhibition 0.1 % 10.1021/jm00163a013
None Unchecked Inhibition 100.0 % 10.1021/jm00163a013
None Unchecked Inhibition nan % 10.1128/aac.01821-09
None Unchecked Inhibitory concentration 0.1 ug ml-1 10.1021/jm00113a026
None Unchecked Inhibitory concentration 0.5 ug ml-1 10.1021/jm00113a026
None Unchecked Inhibitory concentration 100.0 ug ml-1 10.1021/jm00113a026
None Unchecked Kcat 0.01 /s 10.1128/aac.00219-09
None Unchecked Kcat 0.01 /s 10.1128/aac.00387-08
None Unchecked Kcat 0.01 /s 10.1128/aac.00856-09
None Unchecked Kcat 0.01 /s 10.1128/aac.01164-08
None Unchecked Kcat 0.01 /s 10.1128/aac.01284-08
None Unchecked Kcat 0.01 /s 10.1128/aac.01463-07
None Unchecked Kcat 0.015 /s 10.1128/aac.01252-09
None Unchecked Kcat 0.045 /s 10.1128/aac.00608-08
None Unchecked Kcat 0.07 /s 10.1128/aac.01028-07
None Unchecked Kcat 0.08 /s 10.1128/aac.00608-08
None Unchecked Kcat 0.1 /s 10.1128/aac.00197-10
None Unchecked Kcat 0.1 /s 10.1128/aac.00608-08
None Unchecked Kcat 0.1 /s 10.1128/aac.00614-07
None Unchecked Kcat 0.1 /s 10.1128/aac.01058-06
None Unchecked Kcat 0.1 /s 10.1128/aac.01442-09
None Unchecked Kcat 0.1 /s 10.1128/aac.01600-06
None Unchecked Kcat 0.15 /s 10.1128/aac.01410-08
None Unchecked Kcat 0.17 /s 10.1128/aac.01252-09
None Unchecked Kcat 0.2 /s 10.1128/aac.00608-08
None Unchecked Kcat 0.2 /s 10.1128/aac.01252-09
None Unchecked Kcat 0.3 /s 10.1128/aac.01028-07
None Unchecked Kcat 0.41 /s 10.1128/aac.01028-07
None Unchecked Kcat 0.7 /s 10.1128/aac.00858-10
None Unchecked Kcat 1.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 1.3 /s 10.1128/aac.00774-09
None Unchecked Kcat 1.3 /s 10.1128/aac.00858-10
None Unchecked Kcat 1.53 /s 10.1128/aac.00083-07
None Unchecked Kcat 1.7 /s 10.1128/aac.00219-09
None Unchecked Kcat 2.9 /s 10.1128/aac.00218-07
None Unchecked Kcat 3.55 /s 10.1128/aac.00771-10
None Unchecked Kcat 5.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 5.0 /s 10.1128/aac.01410-08
None Unchecked Kcat 5.1 /s 10.1128/aac.00771-10
None Unchecked Kcat 9.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 10.6 /s 10.1128/aac.00614-07
None Unchecked Kcat 13.4 /s 10.1128/aac.01336-09
None Unchecked Kcat 14.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 20.0 /s 10.1128/aac.00961-09
None Unchecked Kcat 26.0 /s 10.1128/aac.01336-09
None Unchecked Kcat 31.4 /s 10.1128/aac.00771-10
None Unchecked Kcat 34.3 /s 10.1128/aac.00017-09
None Unchecked Kcat 37.2 /s 10.1128/aac.00771-10
None Unchecked Kcat 43.0 /s 10.1128/aac.00197-10
None Unchecked Kcat 56.8 /s 10.1128/aac.00771-10
None Unchecked Kcat 66.0 /s 10.1128/aac.00163-08
None Unchecked Kcat 69.0 /s 10.1128/aac.00771-10
None Unchecked Kcat 78.0 /s 10.1128/aac.00693-09
None Unchecked Kcat 81.0 /s 10.1128/aac.00175-08
None Unchecked Kcat 90.0 /s 10.1128/aac.00175-08
None Unchecked Kcat 94.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 98.0 /s 10.1128/aac.01336-09
None Unchecked Kcat 170.0 /s 10.1128/aac.00166-08
None Unchecked Kcat 197.0 /s 10.1128/aac.00227-08
None Unchecked Kcat 250.0 /s 10.1128/aac.01062-07
None Unchecked Kcat 370.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 410.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 440.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 2181.0 /s 10.1128/aac.01337-07
None Unchecked Kcat nan None 10.1128/aac.00098-10
None Unchecked Kcat/Km 0.0016 /uM/s 10.1128/aac.01028-07
None Unchecked Kcat/Km 0.002 /mM/s 10.1128/aac.00608-08
None Unchecked Kcat/Km 0.008 /mM/s 10.1128/aac.00608-08
None Unchecked Kcat/Km 0.01 /uM/s 10.1128/aac.01028-07
None Unchecked Kcat/Km 0.013 /uM/s 10.1128/aac.01028-07
None Unchecked Kcat/Km 0.02 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 0.03 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.03 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 0.03 None 10.1128/aac.00614-07
None Unchecked Kcat/Km 0.031 /uM/s 10.1128/aac.00083-07
None Unchecked Kcat/Km 0.04 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 0.045 /mM/s 10.1128/aac.00608-08
None Unchecked Kcat/Km 0.05 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.14 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.18 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 0.19 /s/microM 10.1128/aac.00218-07
None Unchecked Kcat/Km 0.26 /uM/s 10.1128/aac.00197-10
None Unchecked Kcat/Km 0.34 /s/microM 10.1128/aac.00175-08
None Unchecked Kcat/Km 0.35 /s/microM 10.1128/aac.00774-09
None Unchecked Kcat/Km 0.37 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.38 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.6 microM/s 10.1128/aac.00693-09
None Unchecked Kcat/Km 0.68 /uM/s 10.1128/aac.00166-08
None Unchecked Kcat/Km 0.78 /s/M 10.1128/aac.01025-07
None Unchecked Kcat/Km 0.8 /mM/s 10.1128/aac.00608-08
None Unchecked Kcat/Km 0.95 /s/microM 10.1128/aac.00017-09
None Unchecked Kcat/Km 1.0 10'5/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 1.0 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 1.09 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 1.2 10'5/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 1.2 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 1.3 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 1.4 10'5/M/s 10.1128/aac.01062-07
None Unchecked Kcat/Km 1.5 10'6/M/s 10.1128/aac.01062-07
None Unchecked Kcat/Km 1.5 uM/hr 10.1128/aac.01336-09
None Unchecked Kcat/Km 1.7 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 1.7 10'7/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 1.7 10'8/M/s 10.1128/aac.01337-07
None Unchecked Kcat/Km 1.9 10'6/M/s 10.1128/aac.00227-08
None Unchecked Kcat/Km 2.0 10'6/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 2.0 /uM/s 10.1128/aac.00219-09
None Unchecked Kcat/Km 2.3 10'5/M/s 10.1128/aac.00858-10
None Unchecked Kcat/Km 2.4 10'5/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 3.5 10'5/M/s 10.1128/aac.00858-10
None Unchecked Kcat/Km 3.7 uM/hr 10.1128/aac.01336-09
None Unchecked Kcat/Km 4.1 10'5/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 4.8 uM/hr 10.1128/aac.01336-09
None Unchecked Kcat/Km 5.7 /uM/s 10.1128/aac.00219-09
None Unchecked Kcat/Km 6.9 /s/microM 10.1128/aac.00175-08
None Unchecked Kcat/Km 20.0 /uM/s 10.1128/aac.00050-10
None Unchecked Kcat/Km 20.0 /uM/s 10.1128/aac.01410-08
None Unchecked Kcat/Km 30.0 /uM/s 10.1128/aac.01410-08
None Unchecked Kcat/Km 380.0 /mM/s 10.1128/aac.00961-09
None Unchecked Kcat/Km 380.0 /uM/s 10.1128/aac.00163-08
None Unchecked Kcat/Km 760.0 /uM/s 10.1128/aac.01585-09
None Unchecked Kcat/Km nan None 10.1128/aac.00197-10
None Unchecked Kcat/Km nan None 10.1128/aac.00387-08
None Unchecked Kcat/Km nan None 10.1128/aac.00614-07
None Unchecked Kcat/Km nan None 10.1128/aac.01082-06
None Unchecked Kcat/Km nan None 10.1128/aac.01442-09
None Unchecked Ki 5.0 nM 10.1128/aac.00219-09
None Unchecked Ki 300.0 nM 10.1128/aac.00219-09
None Unchecked Ki 120000.0 nM 10.1128/aac.00693-09
None Unchecked Ki nan None None
None Unchecked Km 0.9 nM 10.1128/aac.01252-09
None Unchecked Km 100.0 nM 10.1128/aac.01252-09
None Unchecked Km 320.0 /s/microM 10.1128/aac.00614-07
None Unchecked Km 1700.0 nM 10.1128/aac.01252-09
None Unchecked Km 2800.0 nM 10.1128/aac.01336-09
None Unchecked Km 3000.0 nM 10.1128/aac.00858-10
None Unchecked Km 4000.0 nM 10.1128/aac.00774-09
None Unchecked Km 4000.0 nM 10.1128/aac.00858-10
None Unchecked Km 5000.0 nM 10.1128/aac.01410-08
None Unchecked Km 7000.0 nM 10.1128/aac.01336-09
None Unchecked Km 8000.0 nM 10.1128/aac.01410-08
None Unchecked Km 13000.0 nM 10.1128/aac.00175-08
None Unchecked Km 13000.0 nM 10.1128/aac.01337-07
None Unchecked Km 15000.0 nM 10.1128/aac.00218-07
None Unchecked Km 30000.0 nM 10.1128/aac.01028-07
None Unchecked Km 32000.0 nM 10.1128/aac.01028-07
None Unchecked Km 34000.0 nM 10.1128/aac.01058-06
None Unchecked Km 43000.0 nM 10.1128/aac.01028-07
None Unchecked Km 49000.0 nM 10.1128/aac.00083-07
None Unchecked Km 50000.0 nM 10.1128/aac.01058-06
None Unchecked Km 61000.0 nM 10.1128/aac.01336-09
None Unchecked Km 63400.0 nM 10.1128/aac.00771-10
None Unchecked Km 81600.0 nM 10.1128/aac.00771-10
None Unchecked Km 95600.0 nM 10.1128/aac.00771-10
None Unchecked Km 100000.0 nM 10.1128/aac.00608-08
None Unchecked Km 103000.0 nM 10.1128/aac.00227-08
None Unchecked Km 133000.0 nM 10.1128/aac.00771-10
None Unchecked Km 152000.0 nM 10.1128/aac.00771-10
None Unchecked Km 160000.0 nM 10.1128/aac.01062-07
None Unchecked Km 168000.0 nM 10.1128/aac.00197-10
None Unchecked Km 174000.0 nM 10.1128/aac.00163-08
None Unchecked Km 230000.0 nM 10.1128/aac.00098-10
None Unchecked Km 240000.0 nM 10.1128/aac.00175-08
None Unchecked Km 250000.0 nM 10.1128/aac.00166-08
None Unchecked Km 259000.0 nM 10.1128/aac.00098-10
None Unchecked Km 261000.0 nM 10.1128/aac.00771-10
None Unchecked Km 304000.0 nM 10.1128/aac.01058-06
None Unchecked Km 320000.0 nM 10.1128/aac.00098-10
None Unchecked Km 345000.0 nM 10.1128/aac.01058-06
None Unchecked Km 350000.0 nM 10.1128/aac.00098-10
None Unchecked Km 360000.0 nM 10.1128/aac.00098-10
None Unchecked Km 1000000.0 nM 10.1128/aac.00608-08
None Unchecked Km 2000000.0 nM 10.1128/aac.01600-06
None Unchecked Km 2200000.0 nM 10.1128/aac.00961-09
None Unchecked Km 25000000.0 nM 10.1128/aac.00608-08
None Unchecked Km 45000000.0 nM 10.1128/aac.00608-08
None Unchecked Km nan None 10.1128/aac.00098-10
None Unchecked Km nan None 10.1128/aac.00197-10
None Unchecked Km nan None 10.1128/aac.00387-08
None Unchecked Km nan None 10.1128/aac.00389-07
None Unchecked Km nan None 10.1128/aac.00614-07
None Unchecked Km nan None 10.1128/aac.00856-09
None Unchecked Km nan None 10.1128/aac.01058-06
None Unchecked Km nan None 10.1128/aac.01082-06
None Unchecked Km nan None 10.1128/aac.01164-08
None Unchecked Km nan None 10.1128/aac.01284-08
None Unchecked Km nan None 10.1128/aac.01442-09
None Unchecked Km nan None 10.1128/aac.01463-07
None Unchecked MIC 0.031 ug.mL-1 10.1021/jm00029a012
None Unchecked MIC 0.17 ug.mL-1 10.1021/jm00388a003
None Unchecked MIC 2.09 ug.mL-1 10.1021/jm00388a003
None Unchecked Morphology nan None 10.1021/jm00163a013
None Unchecked Potency 100.0 nM None
None Unchecked Ratio 0.05 /mM/s 10.1128/aac.01600-06
None Unchecked Ratio 4.0 None 10.1128/aac.00614-07
None Unchecked Vmax 0.01 nmol 10.1128/aac.00389-07
None Unchecked Vmax/Km nan None 10.1128/aac.00389-07

Metabolism Information