Echoside E
AlkaPlorer ID: AK025609
Synonym: 'echoside', 'Echoside E', 'Echoside'
IUPAC Name: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(6-hydroxy-3-methyl-2-oxo-4,7-diphenyl-1,3-benzothiazol-5-yl)oxy]oxane-2-carboxylic acid
Structure
SMILES: CN1C(=O)SC2=C1C(C1=CC=CC=C1)=C(O[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]1O)C(O)=C2C1=CC=CC=C1
InChI: InChI=1S/C26H23NO9S/c1-27-16-14(12-8-4-2-5-9-12)21(35-25-20(31)18(29)19(30)22(36-25)24(32)33)17(28)15(23(16)37-26(27)34)13-10-6-3-7-11-13/h2-11,18-20,22,25,28-31H,1H3,(H,32,33)/t18-,19-,20+,22-,25+/m0/s1
InChIKey: IHUHIFKVCBIAMM-QDSRYJPQSA-N
Reference
p-Terphenyl O-β-glucuronides, DNA topoisomerase inhibitors from Streptomyces sp. LZ35ΔgdmAI
PubChem CID: 76314408
LOTUS: LTS0079432
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | None | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 525.5350000000002
TPSA？: 158.68
MolLogP？: 1.910599999999999
Number of H-Donors: 5
Number of H-Acceptors: 10
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Globisporangium ultimum | Globisporangium ultimum | Activity | None | None | 10.1016/j.bmcl.2014.01.037 |
| Homo sapiens | DNA topoisomerase II alpha | Inhibition | None | % | 10.1016/j.bmcl.2014.01.037 |
| Rhizoctonia solani | Rhizoctonia solani | Activity | None | None | 10.1016/j.bmcl.2014.01.037 |
| None | Molecular identity unknown | Activity | None | None | 10.1016/j.bmcl.2014.01.037 |
| None | Unchecked | Inhibition | None | % | 10.1016/j.bmcl.2014.01.037 |