2,3-Dimethoxyphenazine
AlkaPlorer ID: AK025946
Synonym: None
IUPAC Name: 2,3-dimethoxyphenazine
Structure
SMILES: COC1=CC2=NC3=CC=CC=C3N=C2C=C1OC
InChI: InChI=1S/C14H12N2O2/c1-17-13-7-11-12(8-14(13)18-2)16-10-6-4-3-5-9(10)15-11/h3-8H,1-2H3
InChIKey: YQIADNJBCIVZAI-UHFFFAOYSA-N
Reference
7-Hydroxytropolon aus Pseudomonas sp. [1] / 7-Hydroxy Tropolone from Pseudomonas sp. [1]
PubChem CID: 21679909
LOTUS: LTS0067882
COCONUT: CNP0142443
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Pseudomonas chlororaphis | Pseudomonas | Pseudomonadaceae | Pseudomonadales | Gammaproteobacteria | Pseudomonadota | None | Bacteria |
Properties Information
Molecule Weight: 240.262
TPSA？: 44.24000000000001
MolLogP？: 2.800200000000001
Number of H-Donors: 0
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Quinone reductase 2 | IC50 | 18200.0 | nM | 10.1021/jm1011066 |
| Homo sapiens | Quinone reductase 2 | Inhibition | 80.0 | % | 10.1021/jm1011066 |
| Mus musculus | NAD(P)H dehydrogenase [quinone] 1 | Ratio | 0.8 | None | 10.1021/jm1011066 |
| Mus musculus | RAW264.7 | Inhibition | 29.4 | % | 10.1021/jm1011066 |
| None | Unchecked | Inhibition | 0.0 | % | 10.1021/jm1011066 |