Oxanosine
AlkaPlorer ID: AK026386
Synonym: None
IUPAC Name: 5-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazo[4,5-d][1,3]oxazin-7-one
Structure
SMILES: NC1=NC2=C(N=CN2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)O1
InChI: InChI=1S/C10H12N4O6/c11-10-13-7-4(9(18)20-10)12-2-14(7)8-6(17)5(16)3(1-15)19-8/h2-3,5-6,8,15-17H,1H2,(H2,11,13)/t3-,5-,6-,8-/m1/s1
InChIKey: PWVUOVPUCZNICU-ZIYNGMLESA-N
Reference
Oxanosine, a novel nucleoside from actinomycetes.
PubChem CID: 477547
CAS: 80394-72-5
{NPAtlas: NPA021021
Source
Properties Information
Molecule Weight: 284.228
TPSA？: 156.86
MolLogP？: -2.4218
Number of H-Donors: 4
Number of H-Acceptors: 10
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Escherichia coli | Escherichia coli | MIC | 12.5 | ug.mL-1 | 10.1021/acs.jmedchem.6b00325 |