nojirimycin
AlkaPlorer ID: AK027115
Synonym: '', 'U 51640', 'Nojirimycin', 'Nojirimycin B', 'R 468', '5-Amino-5-deoxy-D-glucopyranose', '(3R,4S,5R,6R)-6-(hydroxymethyl)piperidine-2,3,4,5-tetrol', '(+)-Nojirimycin', 'Galactostatin', '6-(hydroxymethyl)-2,3,4,5-Piperidinetetrol'
IUPAC Name: (3R,4S,5R,6R)-6-(hydroxymethyl)piperidine-2,3,4,5-tetrol
Structure
SMILES: OC[C@H]1NC(O)[C@H](O)[C@@H](O)[C@@H]1O
InChI: InChI=1S/C6H13NO5/c8-1-2-3(9)4(10)5(11)6(12)7-2/h2-12H,1H2/t2-,3-,4+,5-,6?/m1/s1
InChIKey: BGMYHTUCJVZIRP-GASJEMHNSA-N
Reference
Galactostatin, a new .BETA.-galactosidase inhibitor from Streptomyces lydicus.
PubChem CID: 65242
CAS: 15218-38-9
LOTUS: LTS0242193
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces lavendulae | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 179.172
TPSA？: 113.18
MolLogP？: -3.648399999999999
Number of H-Donors: 6
Number of H-Acceptors: 6
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Maltase-glucoamylase | Inhibitory activity | nan | None | 10.1016/S0960-894X(97)00012-7 |
| Rattus norvegicus | Sucrase-isomaltase | Inhibitory activity | nan | None | 10.1016/S0960-894X(97)00012-7 |
| Saccharomyces cerevisiae S288c | Glucoamylase, intracellular sporulation-specific | Ki | 6300.0 | nM | 10.1016/j.bmc.2007.03.073 |
| None | Unchecked | Ki | 900.0 | nM | 10.1016/j.bmc.2007.03.073 |
| None | Unchecked | Ki | 500000.0 | nM | 10.1016/j.bmc.2007.03.073 |
| None | Unchecked | Ki | 900000.0 | nM | 10.1016/j.bmc.2007.03.073 |