2-Hydroxy-3-methylcarbazole
AlkaPlorer ID: AK027921
Synonym: ''
IUPAC Name: 3-methyl-9H-carbazol-2-ol
Structure
SMILES: CC1=CC2=C(C=C1O)NC1=CC=CC=C12
InChI: InChI=1S/C13H11NO/c1-8-6-10-9-4-2-3-5-11(9)14-12(10)7-13(8)15/h2-7,14-15H,1H3
InChIKey: ZLOJFAGTWDOURE-UHFFFAOYSA-N
Reference
Carbazole alkaloids from Clausena excavata and their biological activity
PubChem CID: 3459141
CAS: 24224-30-4
LOTUS: LTS0200915
COCONUT: CNP0267777
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Clausena vestita | Clausena | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 197.237
TPSA？: 36.02
MolLogP？: 3.3351200000000008
Number of H-Donors: 2
Number of H-Acceptors: 1
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Chlorocebus sabaeus | Vero | IC50 | nan | None | 10.1016/j.bmc.2016.12.038 |
| Homo sapiens | HepG2 | IC50 | 14400.0 | nM | 10.1016/j.ejmech.2011.10.047 |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC90 | 41500.0 | nM | 10.1016/j.bmc.2016.12.038 |
| None | ADMET | IC50 | 85200.0 | nM | 10.1016/j.ejmech.2011.10.047 |