2-methoxyphenazine

AlkaPlorer ID: AK028235

Synonym: 'MLS001048992', 'SMR000387038', 'MLS000768124'

IUPAC Name: 2-methoxyphenazine

Structure

SMILES: COC1=CC=C2N=C3C=CC=CC3=NC2=C1

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InChI: InChI=1S/C13H10N2O/c1-16-9-6-7-12-13(8-9)15-11-5-3-2-4-10(11)14-12/h2-8H,1H3

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InChIKey: YGSXHEXJOFMTHZ-UHFFFAOYSA-N

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Properties Information

Molecule Weight: 210.236

TPSA: 35.010000000000005

MolLogP: 2.7916000000000016

Number of H-Donors: 0

Number of H-Acceptors: 3

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Potency 56234.1 nM None
Equus caballus Ferritin light chain Potency 44668.4 nM None
Escherichia coli K-12 Beta-lactamase AmpC Potency 3981.1 nM None
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Potency 2233.4 nM None
Homo sapiens Aldehyde dehydrogenase 1A1 Potency 39810.7 nM None
Homo sapiens Alpha-synuclein Potency 35481.3 nM None
Homo sapiens ATPase family AAA domain-containing protein 5 Potency 12990.0 nM None
Homo sapiens Breast cancer type 1 susceptibility protein Potency 12589.3 nM None
Homo sapiens DNA polymerase beta Potency 50118.7 nM None
Homo sapiens Flap endonuclease 1 Potency 50118.7 nM None
Homo sapiens Glucagon-like peptide 1 receptor Potency 5011.9 nM None
Homo sapiens GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 Potency 39810.7 nM None
Homo sapiens HeLa AC50 73519.0 nM None
Homo sapiens Importin subunit beta-1/Snurportin-1 Potency 112201.8 nM None
Homo sapiens Lysine-specific demethylase 4D-like Potency 28183.8 nM None
Homo sapiens Menin/Histone-lysine N-methyltransferase MLL Potency 14125.4 nM None
Homo sapiens microRNA 21 Potency 2328.1 nM None
Homo sapiens Muscleblind-like protein 1 Potency 12589.3 nM None
Homo sapiens Niemann-Pick C1 protein Potency 3981.1 nM None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 29092.9 nM None
Homo sapiens Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Potency 50118.7 nM None
Homo sapiens Prelamin-A/C Potency 10000.0 nM None
Homo sapiens Quinone reductase 2 IC50 15300.0 nM 10.1021/jm1011066
Homo sapiens Quinone reductase 2 Inhibition 90.0 % 10.1021/jm1011066
Homo sapiens Ras-related protein Rab-9A Potency 2818.4 nM None
Homo sapiens Sphingomyelin phosphodiesterase Potency 25118.9 nM None
Homo sapiens Survival motor neuron protein Potency 11220.2 nM None
Homo sapiens Vitamin D receptor Potency 100000.0 nM None
Human immunodeficiency virus 1 Aberrant vpr protein Potency 44668.4 nM None
Influenza A virus Nonstructural protein 1 Potency 8912.5 nM None
Leishmania mexicana Pyruvate kinase Potency 17782.8 nM None
Mus musculus NAD(P)H dehydrogenase [quinone] 1 Ratio 0.8 None 10.1021/jm1011066
Mus musculus RAW264.7 Inhibition 12.5 % 10.1021/jm1011066
Photinus pyralis Luciferin 4-monooxygenase Potency 16944.1 nM None
Plasmodium falciparum Plasmodium falciparum Potency 8275.3 nM None
Plasmodium falciparum Plasmodium falciparum Potency 13115.4 nM None
None Unchecked AC40 4.107 uM None
None Unchecked EC50 370.0 nM None
None Unchecked EC50 850.0 nM None
None Unchecked Inhibition 16.0 % 10.1021/jm1011066
None Unchecked Potency 2818.4 nM None

Metabolism Information