4-Hydroxybenzylamine; N-Ac
AlkaPlorer ID: AK028287
Synonym: N-Acetyl-4-hydroxybenzylamine, BMY 40660
IUPAC Name: N-[(4-hydroxyphenyl)methyl]acetamide
Structure
SMILES: CC(O)=NCC1=CC=C(O)C=C1
InChI: InChI=1S/C9H11NO2/c1-7(11)10-6-8-2-4-9(12)5-3-8/h2-5,12H,6H2,1H3,(H,10,11)
InChIKey: KVIZYCBDCWXNOQ-UHFFFAOYSA-N
Reference
PubChem CID: 458498
CAS: 34185-04-1
LOTUS: LTS0052372
SuperNatural Ⅲ: SN0196434
COCONUT: CNP0325229
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Actinomadura verrucosospora | Actinomadura | Thermomonosporaceae | Streptosporangiales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 165.192
TPSA？: 52.82000000000001
MolLogP？: 1.8686
Number of H-Donors: 2
Number of H-Acceptors: 2
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Cannabinoid CB1 receptor | Activity | 5.0 | % | 10.1021/jm800807k |
| Homo sapiens | Cannabinoid CB2 receptor | Activity | 7.0 | % | 10.1021/jm800807k |
| Homo sapiens | Cyclooxygenase-1 | Activity | nan | None | 10.1021/jm800807k |
| Homo sapiens | Cyclooxygenase-2 | Activity | nan | None | 10.1021/jm800807k |
| Mus musculus | Mus musculus | Activity | 37.0 | % | 10.1021/jm800807k |
| Mus musculus | Mus musculus | Activity | 50.0 | % | 10.1021/jm800807k |
| Mus musculus | Mus musculus | Activity | 71.0 | % | 10.1021/jm800807k |
| Mus musculus | Mus musculus | Activity | 97.0 | % | 10.1021/jm800807k |
| Mus musculus | Mus musculus | Activity | 128.0 | % | 10.1021/jm800807k |
| Mus musculus | Mus musculus | Activity | 227.0 | % | 10.1021/jm800807k |
| Mus musculus | Mus musculus | Activity | nan | None | 10.1021/jm800807k |
| Rattus norvegicus | Anandamide amidohydrolase | Inhibition | 4.0 | % | 10.1021/jm800807k |