Nornuciferine
AlkaPlorer ID: AK028687
Synonym: 'Sanjoinine Ia', 'Daechualkaloid E'
IUPAC Name: (6aR)-1,2-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Structure
SMILES: COC1=CC2=C3C(=C1OC)C1=CC=CC=C1C[C@H]3NCC2
InChI: InChI=1S/C18H19NO2/c1-20-15-10-12-7-8-19-14-9-11-5-3-4-6-13(11)17(16(12)14)18(15)21-2/h3-6,10,14,19H,7-9H2,1-2H3/t14-/m1/s1
InChIKey: QQKAHDMMPBQDAC-CQSZACIVSA-N
Reference
Alkaloids from Anomianthus dulcis
PubChem CID: 12313579
LOTUS: LTS0131511
SuperNatural Ⅲ: SN0312402-02
NPASS: NPC203784
Source
Properties Information
Molecule Weight: 281.3550000000001
TPSA？: 30.49
MolLogP？: 3.1137000000000006
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| None | ADMET | Inhibition | 82.0 | % | 10.1016/j.bmc.2012.11.038 |
| None | ADMET | Inhibition | 86.0 | % | 10.1016/j.bmc.2012.11.038 |
| None | Unchecked | IC50 | 62900.0 | nM | 10.1016/j.bmc.2012.11.038 |
| None | Unchecked | Inhibition | 5.8 | % | 10.1016/j.bmc.2012.11.038 |
| None | Unchecked | Inhibition | 12.1 | % | 10.1016/j.bmc.2012.11.038 |
| None | Unchecked | Inhibition | 16.2 | % | 10.1016/j.bmc.2012.11.038 |
| None | Unchecked | Inhibition | 17.6 | % | 10.1016/j.bmc.2012.11.038 |
| None | Unchecked | Inhibition | 91.9 | % | 10.1016/j.bmc.2012.11.038 |