Hyacinthacine C5
AlkaPlorer ID: AK029276
Synonym: None
IUPAC Name: (1R,2R,3R,5S,6S,7S,8R)-3-(hydroxymethyl)-5-methyl-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,6,7-tetrol
Structure
SMILES: C[C@H]1[C@H](O)[C@@H](O)[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)N21
InChI: InChI=1S/C9H17NO5/c1-3-6(12)8(14)5-9(15)7(13)4(2-11)10(3)5/h3-9,11-15H,2H2,1H3/t3-,4+,5+,6-,7+,8-,9+/m0/s1
InChIKey: TXKSAMJHOAHOGY-FDQLZJOISA-N
Reference
Isolation of Glycosidase-Inhibiting Hyacinthacines and Related Alkaloids from <i>Scilla socialis</i>
PubChem CID: 16737239
LOTUS: LTS0137534
SuperNatural Ⅲ: SN0362647-02
NPASS: NPC163538
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 219.237
TPSA？: 104.39
MolLogP？: -3.1228
Number of H-Donors: 5
Number of H-Acceptors: 6
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bos taurus | Beta-galactosidase | IC50 | 900000.0 | nM | 10.1021/np0700826 |
| Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) | Beta-galactosidase | IC50 | 48000.0 | nM | 10.1021/np0700826 |
| Coffea arabica | Alpha-galactosidase | Inhibition | 50.0 | % | 10.1021/np0700826 |
| Homo sapiens | Alpha-L-fucosidase I | Inhibition | 50.0 | % | 10.1021/np0700826 |
| None | Unchecked | IC50 | 57000.0 | nM | 10.1021/np0700826 |
| None | Unchecked | IC50 | 77000.0 | nM | 10.1021/np0700826 |
| None | Unchecked | Inhibition | 50.0 | % | 10.1021/np0700826 |