Molecule

Naamine A

AlkaPlorer ID: AK029523

Synonym: 4-[[2-Amino-4-[(4-methoxyphenyl)methyl]-1-methyl-1H-imidazol-5-yl]methyl]phenol, 2-Amino-5-(p-hydroxybenzyl)-4-(p-methoxybenzyl)-1-methylimidazole

IUPAC Name: 4-[[2-amino-5-[(4-methoxyphenyl)methyl]-3-methylimidazol-4-yl]methyl]phenol

Structure

SMILES: COC1=CC=C(CC2=C(CC3=CC=C(O)C=C3)N(C)C(=N)N2)C=C1

InChI: InChI=1S/C19H21N3O2/c1-22-18(12-14-3-7-15(23)8-4-14)17(21-19(22)20)11-13-5-9-16(24-2)10-6-13/h3-10,23H,11-12H2,1-2H3,(H2,20,21)

InChIKey: UKDSUTMIUKSRCH-UHFFFAOYSA-N

Reference

ChemInform Abstract: 2‐Amino‐imidazole Alkaloids from the Marine Sponge Leucetta chagosensis.

PubChem CID: 10019087

CAS: 110189-03-2

LOTUS: LTS0074263

SuperNatural Ⅲ: SN0372601

NPASS: NPC237227

COCONUT: CNP0286912

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Heterocondylus vitalbae	Heterocondylus	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Amycolatopsis mediterranei	Amycolatopsis	Pseudonocardiaceae	Pseudonocardiales	Actinomycetes	Actinomycetota	None	Bacteria
Pseudopestalotiopsis theae	Pseudopestalotiopsis	Sporocadaceae	Xylariales	Sordariomycetes	Ascomycota	Fungi	Eukaryota
Salvia chinensis	Salvia	Lamiaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Cryptocarya moschata	Cryptocarya	Lauraceae	Laurales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Argemone squarrosa	Argemone	Papaveraceae	Ranunculales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Centaurea involucrata	Centaurea	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Artemisia princeps	Artemisia	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Lupinus albus	Lupinus	Fabaceae	Fabales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Leucetta chagosensis	Leucetta	Leucettidae	Clathrinida	Calcarea	Porifera	Metazoa	Eukaryota
Streptomyces nojiriensis	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria
Teucrium flavum	Teucrium	Lamiaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Agave salmiana	Agave	Asparagaceae	Asparagales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 323.396

TPSA？: 74.03

MolLogP？: 2.72847

Number of H-Donors: 3

Number of H-Acceptors: 4

RingCount: 3

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Aspergillus pseudoglaucus	Aspergillus pseudoglaucus	Activity	nan	None	10.1021/np020050c
[Chlorella] fusca	[Chlorella] fusca	Activity	nan	None	10.1021/np020050c
Escherichia coli	Escherichia coli	Activity	nan	None	10.1021/np020050c
Homo sapiens	A-431	TGI	85.0	%	10.1039/C7MD00067G
Microbotryum violaceum	Microbotryum violaceum	Activity	nan	None	10.1021/np020050c
Mycotypha microspora	Mycotypha microspora	Activity	nan	None	10.1021/np020050c
Priestia megaterium	Priestia megaterium	Activity	nan	None	10.1021/np020050c
Pseudomonas aeruginosa	Pseudomonas aeruginosa	EC50	436000.0	nM	10.1016/j.bmcl.2011.09.050
None	Unchecked	IC50	75000.0	nM	10.1016/j.bmcl.2007.04.017