Lynamicin C
AlkaPlorer ID: AK030083
Synonym: None
IUPAC Name: 5,6-dichloro-3-[4-(5,6-dichloro-1H-indol-3-yl)-1H-pyrrol-3-yl]-1H-indole
Structure
SMILES: ClC1=CC2=C(C=C1Cl)C(C1=CNC=C1C1=CNC3=CC(Cl)=C(Cl)C=C13)=CN2
InChI: InChI=1S/C20H11Cl4N3/c21-15-1-9-13(7-26-19(9)3-17(15)23)11-5-25-6-12(11)14-8-27-20-4-18(24)16(22)2-10(14)20/h1-8,25-27H
InChIKey: BMSRAYDJPZCVMP-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | None | Actinomycetaceae | Actinomycetales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 435.1410000000001
TPSA？: 47.37
MolLogP？: 7.924900000000002
Number of H-Donors: 3
Number of H-Acceptors: 0
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Enterococcus faecalis | Enterococcus faecalis | MIC | 5800.0 | nM | 10.1021/np800286d |
| Enterococcus faecium | Enterococcus faecium | MIC | 4600.0 | nM | 10.1021/np800286d |
| Escherichia coli | Escherichia coli | MIC | 15000.0 | nM | 10.1021/np800286d |
| Haemophilus influenzae | Haemophilus influenzae | MIC | 9200.0 | nM | 10.1021/np800286d |
| Haemophilus influenzae | Haemophilus influenzae | MIC | 15000.0 | nM | 10.1021/np800286d |
| Herpesviridae sp. | Herpesviridae sp. | IC50 | 17.2 | ug.mL-1 | 10.1021/np800286d |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 2500.0 | nM | 10.1021/np800286d |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 3500.0 | nM | 10.1021/np800286d |
| Staphylococcus epidermidis | Staphylococcus epidermidis | MIC | 2300.0 | nM | 10.1021/np800286d |
| Streptococcus pneumoniae | Streptococcus pneumoniae | MIC | 46000.0 | nM | 10.1021/np800286d |