"Cusculine
AlkaPlorer ID: AK030399
Synonym: None
IUPAC Name: 1,2,3,5,6-pentamethoxy-10H-acridin-9-one
Structure
SMILES: COC1=CC2=C(C(OC)=C1OC)C(=O)C1=CC=C(OC)C(OC)=C1N2
InChI: InChI=1S/C18H19NO6/c1-21-11-7-6-9-14(16(11)23-3)19-10-8-12(22-2)17(24-4)18(25-5)13(10)15(9)20/h6-8H,1-5H3,(H,19,20)
InChIKey: CCYFNSHESGHUKB-UHFFFAOYSA-N
Reference
Molluscicidal Acridone Alkaloids from Angostura paniculata: Isolation, Structures, and Synthesis
PubChem CID: 44584644
LOTUS: LTS0147292
COCONUT: CNP0080540
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 345.3510000000001
TPSA？: 79.01000000000002
MolLogP？: 2.7243000000000004
Number of H-Donors: 1
Number of H-Acceptors: 6
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Biomphalaria glabrata | Biomphalaria glabrata | LC50 | 20.0 | ppm | 10.1021/np50086a012 |
| Homo sapiens | BT-20 | GI | nan | None | 10.1021/np50086a012 |
| Homo sapiens | HeLa | IC50 | 8.5 | ug.mL-1 | 10.1021/np50086a012 |