Hamigeran D
AlkaPlorer ID: AK031492
Synonym: None
IUPAC Name: (2S,3R,6S,11R)-14-bromo-6,11,15-trimethyl-3-propan-2-yl-12-oxa-10-azatetracyclo[7.7.1.02,6.013,17]heptadeca-1(17),9,13,15-tetraen-8-one
Structure
SMILES: CC1=C(Br)C2=C3C(=N[C@@H](C)O2)C(=O)C[C@]2(C)CC[C@H](C(C)C)[C@@H]2C3=C1
InChI: InChI=1S/C21H26BrNO2/c1-10(2)13-6-7-21(5)9-15(24)19-16-14(17(13)21)8-11(3)18(22)20(16)25-12(4)23-19/h8,10,12-13,17H,6-7,9H2,1-5H3/t12-,13-,17-,21+/m1/s1
InChIKey: GZVNTXSTGFGYHN-APVNGSAXSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 404.3480000000002
TPSA？: 38.66
MolLogP？: 5.413720000000005
Number of H-Donors: 0
Number of H-Acceptors: 3
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | IZ | 3.0 | mm | 10.1021/np9903494 |
| Candida albicans | Candida albicans | Activity | nan | None | 10.1021/np9903494 |
| Enterovirus C | Enterovirus C | Activity | nan | None | 10.1021/np9903494 |
| Escherichia coli | Escherichia coli | Activity | nan | None | 10.1021/np9903494 |
| Herpesviridae sp. | Herpesviridae sp. | Activity | nan | None | 10.1021/np9903494 |
| Mus musculus | P388 | IC50 | 8000.0 | nM | 10.1021/np9903494 |