Molecule

TMC-96

AlkaPlorer ID: AK031818

Synonym: None

IUPAC Name: N-[(2S)-3-hydroxy-1-[[1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopentan-2-yl]amino]-1-oxobutan-2-yl]-3-methylbutanamide

Structure

SMILES: CC(C)CC(O)=N[C@H](C(O)=NC(CC(C)C)C(=O)C1(CO)CO1)C(C)O

InChI: InChI=1S/C18H32N2O6/c1-10(2)6-13(16(24)18(8-21)9-26-18)19-17(25)15(12(5)22)20-14(23)7-11(3)4/h10-13,15,21-22H,6-9H2,1-5H3,(H,19,25)(H,20,23)/t12?,13?,15-,18?/m0/s1

InChIKey: CEWYDURMTVVVNH-CJILZHRVSA-N

Reference

TMC-86A, B and TMC-96, New Proteasome Inhibitors from Streptomyces sp. TC 1084 and Saccharothrix sp. TC 1094. I. Taxonomy, Fermentation, Isolation, and Biological Activities.

PubChem CID: 10317178

LOTUS: LTS0157809

{

NPAtlas: NPA012593

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Saccharothrix sp.	Saccharothrix	Pseudonocardiaceae	Pseudonocardiales	Actinomycetes	Actinomycetota	None	Bacteria

Properties Information

Molecule Weight: 372.46200000000016

TPSA？: 135.24

MolLogP？: 1.44

Number of H-Donors: 4

Number of H-Acceptors: 6

RingCount: 1

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi