3-Formyl-1-hydroxy-7-methoxycarbazole
AlkaPlorer ID: AK032091
Synonym: ''
IUPAC Name: 1-hydroxy-7-methoxy-9H-carbazole-3-carbaldehyde
Structure
SMILES: COC1=CC=C2C(=C1)NC1=C(O)C=C(C=O)C=C12
InChI: InChI=1S/C14H11NO3/c1-18-9-2-3-10-11-4-8(7-16)5-13(17)14(11)15-12(10)6-9/h2-7,15,17H,1H3
InChIKey: KVGOXKTZYBQADZ-UHFFFAOYSA-N
Reference
Claurailas A−D, Cytotoxic Carbazole Alkaloids from the Roots of <i>Clausena harmandiana</i>
PubChem CID: 53324960
LOTUS: LTS0018053
COCONUT: CNP0393588
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Clausena harmandiana | Clausena | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 241.246
TPSA？: 62.32
MolLogP？: 2.8478000000000003
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Chlorocebus sabaeus | Vero | IC50 | 179530.0 | nM | 10.1021/np100654m |
| Homo sapiens | KB | IC50 | 10690.0 | nM | 10.1021/np100654m |
| Homo sapiens | NCI-H187 | IC50 | 10360.0 | nM | 10.1021/np100654m |