8-methoxy-4-methylquinolin-2-ol
AlkaPlorer ID: AK033324
Synonym: None
IUPAC Name: 8-methoxy-4-methyl-1H-quinolin-2-one
Structure
SMILES: COC1=CC=CC2=C(C)C=C(O)N=C12
InChI: InChI=1S/C11H11NO2/c1-7-6-10(13)12-11-8(7)4-3-5-9(11)14-2/h3-6H,1-2H3,(H,12,13)
InChIKey: WHZDFFGNQINQSU-UHFFFAOYSA-N
Reference
Meroditerpenoids from a Formosan Soft Coral <i>Nephthea </i><i>c</i><i>habrolii</i>
PubChem CID: 782123
CAS: 30198-01-7
SuperNatural Ⅲ: SN0410800
COCONUT: CNP0270044
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 189.214
TPSA？: 42.35
MolLogP？: 2.25742
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Cytochrome P450 19A1 | IC50 | 105800.0 | nM | 10.1021/jm801335z |
| Homo sapiens | LNCaP | IC50 | 105800.0 | nM | 10.1021/jm801335z |
| Homo sapiens | MCF7 | IC50 | 105800.0 | nM | 10.1021/jm801335z |
| Homo sapiens | Quinone reductase 2 | IC50 | 24100.0 | nM | 10.1021/jm801335z |
| None | NON-PROTEIN TARGET | IC50 | 105800.0 | nM | 10.1021/jm801335z |