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Picrasidine Q

AlkaPlorer ID: AK033985

Synonym: None

IUPAC Name: 4-hydroxy-3-methoxy-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one

Structure

SMILES: COC1=C(O)C2=NC=CC3=C2N(C1=O)C1=CC=CC=C31

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InChI: InChI=1S/C15H10N2O3/c1-20-14-13(18)11-12-9(6-7-16-11)8-4-2-3-5-10(8)17(12)15(14)19/h2-7,18H,1H3

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InChIKey: HJFNTSGIQCFHGP-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Picrasma quassioides Picrasma Simaroubaceae Sapindales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 266.256

TPSA？: 63.830000000000005

MolLogP？: 2.1529

Number of H-Donors: 1

Number of H-Acceptors: 5

RingCount: 4

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens A549 ED50 16.2 ug ml-1 10.1021/np030277n
Homo sapiens HEK293 Activity nan None 10.1021/np400701k
Homo sapiens MCF7 ED50 18.1 ug ml-1 10.1021/np030277n
Homo sapiens Protein-tyrosine phosphatase 1B Inhibition 55.9 % 10.1016/j.bmcl.2015.03.014
Plasmodium falciparum Plasmodium falciparum IC50 2.957 ug.mL-1 10.1021/np030277n
Plasmodium falciparum Plasmodium falciparum IC50 3.525 ug.mL-1 10.1021/np030277n
Tobacco mosaic virus Tobacco mosaic virus Inhibition 25.6 % 10.1021/jf901632j
Tobacco mosaic virus Tobacco mosaic virus Inhibition 35.7 % 10.1021/jf901632j
Tobacco mosaic virus Tobacco mosaic virus Inhibition 42.9 % 10.1021/jf901632j
Tobacco mosaic virus Tobacco mosaic virus Inhibition 52.6 % 10.1021/jf901632j
Tobacco mosaic virus Tobacco mosaic virus Inhibition 53.8 % 10.1021/jf901632j
Tobacco mosaic virus Tobacco mosaic virus Inhibition 66.7 % 10.1021/jf901632j
None Unchecked Inhibition nan % 10.1021/np400701k

Metabolism Information