Limazepine F
AlkaPlorer ID: AK034637
Synonym: None
IUPAC Name: (6R,6aS,8E)-8-ethylidene-6-hydroxy-6,6a,7,9-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-11-one
Structure
SMILES: C/C=C1\C[C@H]2[C@@H](O)NC3=CC=CC=C3C(=O)N2C1
InChI: InChI=1S/C14H16N2O2/c1-2-9-7-12-13(17)15-11-6-4-3-5-10(11)14(18)16(12)8-9/h2-6,12-13,15,17H,7-8H2,1H3/b9-2+/t12-,13+/m0/s1
InChIKey: ULQQQQMOGBDJEB-PHVGEZJSSA-N
Reference
Limazepines A−F, Pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian <i>Micrococcus</i> sp.
PubChem CID: 42639503
LOTUS: LTS0243626
SuperNatural Ⅲ: SN0373715-02
NPASS: NPC169267
{NPAtlas: NPA001599
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Micrococcus sp. | Micrococcus | Micrococcaceae | Micrococcales | Actinomycetes | Actinomycetota | None | Bacteria |
| None | Micrococcus | Micrococcaceae | Micrococcales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 244.294
TPSA？: 52.57
MolLogP？: 1.5913
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | Activity | None | None | 10.1021/np800827w |
| Candida albicans | Candida albicans | Activity | None | None | 10.1021/np800827w |
| Escherichia coli | Escherichia coli | IZ | None | None | 10.1021/np800827w |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | IZ | None | None | 10.1021/np800827w |
| Rhizomucor miehei | Rhizomucor miehei | Activity | None | None | 10.1021/np800827w |
| Staphylococcus aureus | Staphylococcus aureus | IZ | None | None | 10.1021/np800827w |