1-[3-(3,4-dimethoxyphenyl)-4-(morpholine-4-carbonyl)-1,2-oxazol-5-yl]ethan-1-ol
AlkaPlorer ID: AK035435
Synonym: None
IUPAC Name: [3-(3,4-dimethoxyphenyl)-5-[(1S)-1-hydroxyethyl]-1,2-oxazol-4-yl]-morpholin-4-ylmethanone
Structure
SMILES: COC1=CC=C(C2=NOC([C@H](C)O)=C2C(=O)N2CCOCC2)C=C1OC
InChI: InChI=1S/C18H22N2O6/c1-11(21)17-15(18(22)20-6-8-25-9-7-20)16(19-26-17)12-4-5-13(23-2)14(10-12)24-3/h4-5,10-11,21H,6-9H2,1-3H3/t11-/m0/s1
InChIKey: ZSFNWTCAPHIRJG-NSHDSACASA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 362.3820000000002
TPSA？: 94.26
MolLogP？: 1.8845
Number of H-Donors: 1
Number of H-Acceptors: 7
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Plasmodium falciparum | Inhibition | 2.0 | % | 10.6019/CHEMBL4888484 |
| Plasmodium falciparum | Plasmodium falciparum | Z score | -0.39 | None | 10.6019/CHEMBL4888484 |