1-methyluracil
AlkaPlorer ID: AK035702
Synonym: '27942-00-3'
IUPAC Name: 1-methylpyrimidine-2,4-dione
Structure
SMILES: CN1C=CC(O)=NC1=O
InChI: InChI=1S/C5H6N2O2/c1-7-3-2-4(8)6-5(7)9/h2-3H,1H3,(H,6,8,9)
InChIKey: XBCXJKGHPABGSD-UHFFFAOYSA-N
Reference
ChemInform Abstract: SUBSTANCES ISOLATED FROM MELOCHIA PYRAMIDATA L
PubChem CID: 12009
CAS: 27942-00-3
LOTUS: LTS0146093
COCONUT: CNP0199194
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Alangium salviifolium | Alangium | Cornaceae | Cornales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 126.115
TPSA？: 55.12
MolLogP？: -0.5141
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Protein cereblon | IC50 | 65700.0 | nM | 10.1021/acsmedchemlett.0c00440 |
| Homo sapiens | Protein cereblon | Ki | 30800.0 | nM | 10.1021/acsmedchemlett.0c00440 |