Naamine C; 5'-Methoxy, 2'-deoxy, 4'-O-de-Me
AlkaPlorer ID: AK035711
Synonym: Naamine G
IUPAC Name: 4-[[2-amino-5-[(4-methoxyphenyl)methyl]-3-methylimidazol-4-yl]methyl]-2,6-dimethoxyphenol
Structure
SMILES: COC1=CC=C(CC2=C(CC3=CC(OC)=C(O)C(OC)=C3)N(C)C(=N)N2)C=C1
InChI: InChI=1S/C21H25N3O4/c1-24-17(10-14-11-18(27-3)20(25)19(12-14)28-4)16(23-21(24)22)9-13-5-7-15(26-2)8-6-13/h5-8,11-12,25H,9-10H2,1-4H3,(H2,22,23)
InChIKey: DMFFDOWRZFDQGT-UHFFFAOYSA-N
Reference
New Imidazole Alkaloids from the Indonesian Sponge <i>Leucetta </i><i>c</i><i>hagosensis</i>
PubChem CID: 11153300
CAS: 700813-14-5
LOTUS: LTS0127160
NPASS: NPC247251
COCONUT: CNP0327450
Source
Properties Information
Molecule Weight: 383.448
TPSA？: 92.49
MolLogP？: 2.74567
Number of H-Donors: 3
Number of H-Acceptors: 6
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Artemia salina | Artemia salina | Activity | 10.0 | % | 10.1021/np0305223 |
| Cladosporium herbarum | Cladosporium herbarum | IZ | 20.0 | mm | 10.1021/np0305223 |
| Homo sapiens | HeLa | Activity | 29.0 | % | 10.1021/np0305223 |
| Mus musculus | L5178Y | Activity | 46.0 | % | 10.1021/np0305223 |
| Rattus norvegicus | PC-12 | Activity | nan | None | 10.1021/np0305223 |