Makalikone ester
AlkaPlorer ID: AK035731
Synonym: '(-)-Makalikone ester', 'makalikone ester'
IUPAC Name: [(7E,9E)-10-chloro-2,2-dimethyl-5-methylidenedeca-7,9-dien-3-yl] (2S)-1-methyl-5-oxopyrrolidine-2-carboxylate
Structure
SMILES: C=C(C/C=C/C=C/Cl)CC(OC(=O)[C@@H]1CCC(=O)N1C)C(C)(C)C
InChI: InChI=1S/C19H28ClNO3/c1-14(9-7-6-8-12-20)13-16(19(2,3)4)24-18(23)15-10-11-17(22)21(15)5/h6-8,12,15-16H,1,9-11,13H2,2-5H3/b7-6+,12-8+/t15-,16?/m0/s1
InChIKey: PBUCOVRNOZGUGN-OPPOLKRCSA-N
Reference
Malyngamides O and P from the Sea Hare <i>Stylocheilus longicauda</i>
PubChem CID: 10043668
LOTUS: LTS0049322
NPASS: NPC485860
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Stylocheilus longicauda | Stylocheilus | Aplysiidae | Aplysiida | Gastropoda | Mollusca | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 353.8900000000001
TPSA？: 46.61000000000001
MolLogP？: 4.210200000000004
Number of H-Donors: 0
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A549 | IC50 | 2.5 | ug.mL-1 | 10.1021/np990640j |
| Mus musculus | P388 | IC50 | 2.5 | ug.mL-1 | 10.1021/np990640j |
| None | NON-PROTEIN TARGET | IC50 | 2.5 | ug.mL-1 | 10.1021/np990640j |