(+)-Nornantenine
AlkaPlorer ID: AK036502
Synonym: 'Nornantenine', 'N-Nornantenine'
IUPAC Name: (12S)-18,19-dimethoxy-5,7-dioxa-13-azapentacyclo[10.7.1.02,10.04,8.016,20]icosa-1(20),2,4(8),9,16,18-hexaene
Structure
SMILES: COC1=CC2=C3C(=C1OC)C1=CC4=C(C=C1C[C@@H]3NCC2)OCO4
InChI: InChI=1S/C19H19NO4/c1-21-16-6-10-3-4-20-13-5-11-7-14-15(24-9-23-14)8-12(11)18(17(10)13)19(16)22-2/h6-8,13,20H,3-5,9H2,1-2H3/t13-/m0/s1
InChIKey: JWXKBCGJLCEZTJ-ZDUSSCGKSA-N
Reference
Alkaloids of<i>Siparuna tonduziana</i>
PubChem CID: 14395308
LOTUS: LTS0096488
SuperNatural Ⅲ: SN0177507-02
NPASS: NPC298008
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 325.36400000000015
TPSA？: 48.95
MolLogP？: 2.8424000000000005
Number of H-Donors: 1
Number of H-Acceptors: 5
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Electrophorus electricus | Acetylcholinesterase | IC50 | 205550.0 | nM | 10.1016/j.bmc.2016.07.043 |
| Electrophorus electricus | Acetylcholinesterase | Inhibition | 50.38 | % | 10.1016/j.bmc.2016.07.043 |
| Equus caballus | Cholinesterase | IC50 | 94450.0 | nM | 10.1016/j.bmc.2016.07.043 |
| Equus caballus | Cholinesterase | Inhibition | 75.81 | % | 10.1016/j.bmc.2016.07.043 |
| None | Unchecked | Ratio IC50 | 0.46 | None | 10.1016/j.bmc.2016.07.043 |
| None | Unchecked | Ratio IC50 | 2.18 | None | 10.1016/j.bmc.2016.07.043 |