Navigation

name Structure Reference Source Properties Activities Metabolism

alpha-Homomannojirimycin

AlkaPlorer ID: AK036550

Synonym: '', 'beta-Homomannojirimycin', '(+)-alpha-Homomannojirimycin', 'alpha-Homonojirimycin', 'beta-Homonojirimycin', '(+)-alpha-Homonojirimycin'

IUPAC Name: (2R,3R,5R,6S)-2,6-bis(hydroxymethyl)piperidine-3,4,5-triol

Structure

SMILES: OC[C@@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

copy

InChI: InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4+,5-,6-,7+/m1/s1

copy

InChIKey: CLVUFWXGNIFGNC-BIVRFLNRSA-N

copy

Source

Species Genus Family Order Class Phylum Kingdom Domain
Suregada glomerulata Suregada Euphorbiaceae Malpighiales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 193.199

TPSA？: 113.18

MolLogP？: -3.605899999999999

Number of H-Donors: 6

Number of H-Acceptors: 6

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens Alpha-galactosidase A Inhibition 50.0 % 10.1021/jm970836l
Homo sapiens Alpha-L-fucosidase I IC50 2600.0 nM 10.1021/jm970836l
Homo sapiens Maltase-glucoamylase IC50 3200.0 nM 10.1021/jm970836l
Homo sapiens Maltase-glucoamylase Ki 450.0 nM 10.1021/jm970836l
Rattus norvegicus Acidic alpha-glucosidase IC50 3000.0 nM 10.1021/jm970836l
Rattus norvegicus Acidic alpha-glucosidase IC50 4600.0 nM 10.1021/jm970836l
Rattus norvegicus Acidic alpha-glucosidase IC50 5000.0 nM 10.1021/jm970836l
Rattus norvegicus Alpha-L-fucosidase I IC50 4400.0 nM 10.1021/jm970836l
Rattus norvegicus Trehalase IC50 360000.0 nM 10.1021/jm970836l
None Unchecked IC50 19250.0 nM 10.1016/j.bmc.2013.07.048
None Unchecked Inhibition 50.0 % 10.1021/jm970836l

Metabolism Information