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Sid506292

AlkaPlorer ID: AK036830

Synonym: None

IUPAC Name: 3,5-dimethyl-3-(4-methylpent-3-enyl)-11H-pyrano[3,2-a]carbazol-9-ol

Structure

SMILES: CC(C)=CCCC1(C)C=CC2=C(O1)C(C)=CC1=C2NC2=C1C=CC(O)=C2

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InChI: InChI=1S/C23H25NO2/c1-14(2)6-5-10-23(4)11-9-18-21-19(12-15(3)22(18)26-23)17-8-7-16(25)13-20(17)24-21/h6-9,11-13,24-25H,5,10H2,1-4H3

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InChIKey: DWMBXHWBPZZCTN-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Murraya euchrestifolia Murraya Rutaceae Sapindales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 347.4580000000001

TPSA？: 45.25

MolLogP？: 6.2458200000000055

Number of H-Donors: 2

Number of H-Acceptors: 2

RingCount: 4

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Potency 79432.8 nM None
Equus caballus Ferritin light chain Potency 35481.3 nM None
Homo sapiens 786-0 GI50 25003.45 nM None
Homo sapiens A549 GI50 25003.45 nM None
Homo sapiens ACHN GI50 25003.45 nM None
Homo sapiens Alpha-synuclein Potency 22387.2 nM None
Homo sapiens Ataxin-2 Potency 28183.8 nM None
Homo sapiens Bromodomain adjacent to zinc finger domain protein 2B Potency 44668.4 nM None
Homo sapiens CCRF-CEM GI50 25003.45 nM None
Homo sapiens COLO 205 GI50 25003.45 nM None
Homo sapiens DLD-1 GI50 25003.45 nM None
Homo sapiens DMS-114 GI50 25003.45 nM None
Homo sapiens DMS-273 GI50 25003.45 nM None
Homo sapiens DNA polymerase beta Potency 89125.1 nM None
Homo sapiens Geminin Potency 5804.8 nM None
Homo sapiens Geminin Potency 29092.9 nM None
Homo sapiens Glucagon-like peptide 1 receptor Potency 28183.8 nM None
Homo sapiens HCC 2998 GI50 25003.45 nM None
Homo sapiens HCT-116 GI50 25003.45 nM None
Homo sapiens HCT-15 GI50 25003.45 nM None
Homo sapiens HEK293 EC50 55926.0 nM None
Homo sapiens HEK293 IC50 15324.0 nM None
Homo sapiens HepG2 Potency 11220.2 nM None
Homo sapiens Histone acetyltransferase GCN5 Potency 39810.7 nM None
Homo sapiens Histone-lysine N-methyltransferase MLL Potency 44668.4 nM None
Homo sapiens HL-60 GI50 22542.39 nM None
Homo sapiens HOP-18 GI50 7362.07 nM None
Homo sapiens HOP-18 GI50 7413.1 nM 10.1021/np000020e
Homo sapiens HOP-62 GI50 25003.45 nM None
Homo sapiens HOP-92 GI50 25003.45 nM None
Homo sapiens HT-29 GI50 25003.45 nM None
Homo sapiens IGROV-1 GI50 25003.45 nM None
Homo sapiens Insulin-degrading enzyme EC50 41004.0 nM None
Homo sapiens Insulin-degrading enzyme EC50 54690.0 nM None
Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic Potency 29092.9 nM None
Homo sapiens K562 GI50 25003.45 nM None
Homo sapiens KM12 GI50 25003.45 nM None
Homo sapiens KM-20L2 GI50 25003.45 nM None
Homo sapiens LOX IMVI GI50 25003.45 nM None
Homo sapiens LXFL 529 GI50 25003.45 nM None
Homo sapiens Lysine-specific demethylase 4A Potency 44668.4 nM None
Homo sapiens Lysosomal alpha-glucosidase Potency 44668.4 nM None
Homo sapiens M14 GI50 25003.45 nM None
Homo sapiens M19-MEL GI50 25003.45 nM None
Homo sapiens Malme-3M GI50 25003.45 nM None
Homo sapiens Microtubule-associated protein tau Potency 5011.9 nM None
Homo sapiens Microtubule-associated protein tau Potency 28183.8 nM None
Homo sapiens Microtubule-associated protein tau Potency 39810.7 nM None
Homo sapiens MOLT-4 GI50 3.236 nM 10.1021/np000020e
Homo sapiens MOLT-4 GI50 25003.45 nM None
Homo sapiens MOLT-4 TGI 25118.86 nM 10.1021/np000020e
Homo sapiens Mothers against decapentaplegic homolog 3 Potency 11220.2 nM None
Homo sapiens NCI-H226 GI50 25003.45 nM None
Homo sapiens NCI-H322M GI50 25003.45 nM None
Homo sapiens NCI-H460 GI50 25003.45 nM None
Homo sapiens NCI-H522 GI50 6760.83 nM 10.1021/np000020e
Homo sapiens NCI-H522 GI50 6823.39 nM None
Homo sapiens Neuropeptide S receptor Potency 25118.9 nM None
Homo sapiens OVCAR-3 GI50 25003.45 nM None
Homo sapiens OVCAR-4 GI50 22698.65 nM None
Homo sapiens OVCAR-5 GI50 25003.45 nM None
Homo sapiens OVCAR-8 GI50 25003.45 nM None
Homo sapiens Rap guanine nucleotide exchange factor 3 Potency 50118.7 nM None
Homo sapiens RPMI-8226 GI50 25003.45 nM None
Homo sapiens RXF 393 GI50 25003.45 nM None
Homo sapiens SF-268 GI50 25003.45 nM None
Homo sapiens SF-539 GI50 25003.45 nM None
Homo sapiens SK-MEL-2 GI50 25003.45 nM None
Homo sapiens SK-MEL-28 GI50 25003.45 nM None
Homo sapiens SK-MEL-5 GI50 25003.45 nM None
Homo sapiens SK-OV-3 GI50 25003.45 nM None
Homo sapiens SN12C GI50 25003.45 nM None
Homo sapiens SNB-19 GI50 25003.45 nM None
Homo sapiens SNB-78 GI50 25003.45 nM None
Homo sapiens Sphingomyelin phosphodiesterase Potency 141253.8 nM None
Homo sapiens SR GI50 24043.63 nM None
Homo sapiens SW-620 GI50 25003.45 nM None
Homo sapiens TAR DNA-binding protein 43 Potency 5623.4 nM None
Homo sapiens TK-10 GI50 25003.45 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 16360.1 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 29092.9 nM None
Homo sapiens U-251 GI50 25003.45 nM None
Homo sapiens UACC-62 GI50 25003.45 nM None
Homo sapiens UO-31 GI50 25003.45 nM None
Homo sapiens X-box-binding protein 1 IC50 5960.0 nM None
Homo sapiens XF498 GI50 25003.45 nM None
Human immunodeficiency virus 1 Aberrant vpr protein Potency 63095.7 nM None
Mus musculus DNA damage-inducible transcript 3 protein IC50 6040.0 nM None
Mus musculus Nuclear receptor ROR-gamma Potency 35481.3 nM None
Photinus pyralis Luciferin 4-monooxygenase Potency 23934.1 nM None
Plasmodium falciparum Plasmodium falciparum Potency 10417.9 nM None
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Potency 22387.2 nM None
Streptococcus Streptococcus EC50 5069.0 nM None
Streptococcus pyogenes serotype M1 Streptokinase A EC50 2645.0 nM None
Streptococcus pyogenes serotype M1 Streptokinase A EC50 150000.0 nM None
Streptococcus sp. 'group A' Streptococcus sp. 'group A' EC50 2613.0 nM None
None Unchecked AC50 5376.0 nM None
None Unchecked AC50 6287.0 nM None
None Unchecked EC50 29100.0 nM None
None Unchecked EC50 80000.0 nM None
None Unchecked Potency 7943.3 nM None
None Unchecked Potency 10000.0 nM None
None Unchecked Potency 18356.4 nM None
None Unchecked Potency 29092.9 nM None
None Unchecked Potency 32642.7 nM None

Metabolism Information