Oxomaritidine
AlkaPlorer ID: AK036952
Synonym: '(+)-Oxomaritidine'
IUPAC Name: (1R,10S)-4,5-dimethoxy-9-azatetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6,13-tetraen-12-one
Structure
SMILES: COC1=CC2=C(C=C1OC)[C@@]13C=CC(=O)C[C@@H]1N(CC3)C2
InChI: InChI=1S/C17H19NO3/c1-20-14-7-11-10-18-6-5-17(13(11)9-15(14)21-2)4-3-12(19)8-16(17)18/h3-4,7,9,16H,5-6,8,10H2,1-2H3/t16-,17-/m0/s1
InChIKey: ZBFKHAADSKNAMY-IRXDYDNUSA-N
Reference
Crinane and Lycorane Type Alkaloids from Zephyranthes citrina
PubChem CID: 44195367
LOTUS: LTS0161912
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Zephyranthes citrina | Zephyranthes | Amaryllidaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 285.3430000000001
TPSA？: 38.77
MolLogP？: 2.0585
Number of H-Donors: 0
Number of H-Acceptors: 4
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | IC50 | 2.8 | ug.mL-1 | 10.1016/j.bmcl.2019.126642 |
| None | NON-PROTEIN TARGET | GI50 | 64000.0 | nM | 10.1016/j.ejmech.2016.05.004 |
| None | NON-PROTEIN TARGET | GI50 | 100000.0 | nM | 10.1016/j.ejmech.2016.05.004 |