Acetyl-leucyl-valyl-argininal
AlkaPlorer ID: AK036979
Synonym: None
IUPAC Name: (2S)-2-acetamido-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-4-methylpentanamide
Structure
SMILES: CC(O)=N[C@@H](CC(C)C)C(O)=N[C@H](C(O)=N[C@H](C=O)CCCNC(=N)N)C(C)C
InChI: InChI=1S/C19H36N6O4/c1-11(2)9-15(23-13(5)27)17(28)25-16(12(3)4)18(29)24-14(10-26)7-6-8-22-19(20)21/h10-12,14-16H,6-9H2,1-5H3,(H,23,27)(H,24,29)(H,25,28)(H4,20,21,22)/t14-,15-,16-/m0/s1
InChIKey: SEQYPUIPGIGBNQ-JYJNAYRXSA-N
Reference
Leupeptins Produced by the Marine<i>Alteromonas</i>sp. B-10–31
PubChem CID: 10386993
LOTUS: LTS0086848
SuperNatural Ⅲ: SN0343433-01
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | None | Alteromonadaceae | Alteromonadales | Gammaproteobacteria | Pseudomonadota | None | Bacteria |
Properties Information
Molecule Weight: 412.5350000000002
TPSA？: 176.74
MolLogP？: 2.1458700000000013
Number of H-Donors: 6
Number of H-Acceptors: 5
RingCount: 0
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bos taurus | Cathepsin B | IC50 | 130000.0 | nM | 10.1021/jm00060a016 |
| Bos taurus | Plasminogen | IC50 | nan | nM | 10.1021/jm00060a016 |
| Bos taurus | Thrombin | IC50 | nan | nM | 10.1021/jm00060a016 |
| Bos taurus | Trypsin I | IC50 | nan | nM | 10.1021/jm00060a016 |
| Homo sapiens | Plasma kallikrein | IC50 | 16000.0 | nM | 10.1021/jm00060a016 |