2-Aminoimidazole
AlkaPlorer ID: AK037148
Synonym: 1H-Imidazol-2-amine, 2-Aminoglyoxaline
IUPAC Name: 1H-imidazol-2-amine
Structure
SMILES: N=C1NC=CN1
InChI: InChI=1S/C3H5N3/c4-3-5-1-2-6-3/h1-2H,(H3,4,5,6)
InChIKey: DEPDDPLQZYCHOH-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Halichondria | Halichondriidae | Suberitida | Demospongiae | Porifera | Metazoa | Eukaryota |
| Mundulea sericea | Mundulea | Fabaceae | Fabales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Leucetta sp. | Leucetta | Leucettidae | Clathrinida | Calcarea | Porifera | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 83.09400000000001
TPSA？: 55.43
MolLogP？: -0.1777300000000001
Number of H-Donors: 3
Number of H-Acceptors: 1
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Arginase-1 | Ki | 3600000.0 | nM | 10.1021/jm100306a |
| Mus musculus | Nitric oxide synthase, inducible | IC50 | 65000.0 | nM | 10.1021/jm100306a |
| Rattus norvegicus | GABA-A receptor; anion channel | Inhibition | 0.0 | % | 10.1021/jm00395a008 |
| Rattus norvegicus | Nitric-oxide synthase, brain | IC50 | 65000.0 | nM | 10.1021/jm100306a |
| None | No relevant target | pKa | 8.46 | None | 10.1021/jm00111a020 |
| None | No relevant target | pKa | 8.46 | None | 10.1021/jm950589q |
| None | No relevant target | pKa | 8.46 | None | 10.1021/jm970488n |