Coreximine
AlkaPlorer ID: AK037195
Synonym: None
IUPAC Name: (13aS)-3,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,11-diol
Structure
SMILES: COC1=CC2=C(C=C1O)C[C@H]1C3=CC(O)=C(OC)C=C3CCN1C2
InChI: InChI=1S/C19H21NO4/c1-23-18-7-11-3-4-20-10-13-8-19(24-2)16(21)6-12(13)5-15(20)14(11)9-17(18)22/h6-9,15,21-22H,3-5,10H2,1-2H3/t15-/m0/s1
InChIKey: BWUQAWCUJMATJS-HNNXBMFYSA-N
Reference
7,7-Dimethylaporphine Alkaloids from the Stem of <i>Guatteriopsis friesiana</i>
PubChem CID: 7037179
CAS: 483-45-4
LOTUS: LTS0261253
SuperNatural Ⅲ: SN0037633-01
NPASS: NPC88249
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Papaver somniferum | Papaver | Papaveraceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Guatteria hispida | Guatteria | Annonaceae | Magnoliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Aloe microstigma | Aloe | Asphodelaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 327.3800000000001
TPSA？: 62.16
MolLogP？: 2.770500000000001
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Leishmania amazonensis | Leishmania amazonensis | Activity | nan | None | 10.1021/np50109a003 |
| Leishmania braziliensis | Leishmania braziliensis | Activity | nan | None | 10.1021/np50109a003 |
| Leishmania donovani | Leishmania donovani | Activity | nan | None | 10.1021/np50109a003 |
| Trypanosoma cruzi | Trypanosoma cruzi | Activity | 0.0 | % | 10.1021/np50109a003 |
| None | NON-PROTEIN TARGET | Activity | 1.4 | None | 10.1021/np100013r |