Chondramide C
AlkaPlorer ID: AK037378
Synonym: None
IUPAC Name: (4R,7R,10S,13S,15E,17R,18R)-4-(4-hydroxyphenyl)-7-(1H-indol-3-ylmethyl)-8,10,13,15,17,18-hexamethyl-1-oxa-5,8,11-triazacyclooctadec-15-ene-2,6,9,12-tetrone
Structure
SMILES: C/C1=C\[C@@H](C)[C@@H](C)OC(=O)C[C@H](C2=CC=C(O)C=C2)N=C(O)[C@@H](CC2=CNC3=CC=CC=C23)N(C)C(=O)[C@H](C)N=C(O)[C@@H](C)C1
InChI: InChI=1S/C35H44N4O6/c1-20-15-21(2)24(5)45-32(41)18-30(25-11-13-27(40)14-12-25)38-34(43)31(17-26-19-36-29-10-8-7-9-28(26)29)39(6)35(44)23(4)37-33(42)22(3)16-20/h7-15,19,21-24,30-31,36,40H,16-18H2,1-6H3,(H,37,42)(H,38,43)/b20-15+/t21-,22+,23+,24-,30-,31-/m1/s1
InChIKey: NCRSWJPOFRASIF-HPUNWYTPSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Chondromyces crocatus | Chondromyces | Polyangiaceae | Polyangiales | None | Myxococcota | None | Bacteria |
Properties Information
Molecule Weight: 616.7590000000001
TPSA？: 147.81
MolLogP？: 6.229800000000005
Number of H-Donors: 4
Number of H-Acceptors: 6
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HFF | Activity | nan | None | 10.1021/np400196w |
| Toxoplasma gondii | Toxoplasma gondii | EC50 | 480.0 | nM | 10.1021/np400196w |