7-amino-4-hydroxynaphthalene-2-sulfonic acid
AlkaPlorer ID: AK038672
Synonym: None
IUPAC Name: 7-amino-4-hydroxynaphthalene-2-sulfonic acid
Structure
SMILES: NC1=CC=C2C(O)=CC(S(=O)(=O)O)=CC2=C1
InChI: InChI=1S/C10H9NO4S/c11-7-1-2-9-6(3-7)4-8(5-10(9)12)16(13,14)15/h1-5,12H,11H2,(H,13,14,15)
InChIKey: KYARBIJYVGJZLB-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Vitis vinifera | Vitis | Vitaceae | Vitales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 239.252
TPSA？: 100.62
MolLogP？: 1.3743
Number of H-Donors: 3
Number of H-Acceptors: 4
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Emericella nidulans | RmtA | IC50 | 590000.0 | nM | 10.1021/jm061213n |
| Homo sapiens | Ataxin-2 | Potency | 19952.6 | nM | None |
| Homo sapiens | Caspase-6 | AC50 | 2150.0 | nM | None |
| Homo sapiens | Chromobox protein homolog 1 | Potency | 56234.1 | nM | None |
| Homo sapiens | DNA polymerase eta | Potency | 5623.4 | nM | None |
| Homo sapiens | DNA polymerase iota | Potency | 8912.5 | nM | None |
| Homo sapiens | DNA polymerase kappa | Potency | 14125.4 | nM | None |
| Homo sapiens | Dual specificity protein phosphatase 3 | IC50 | 3430.0 | nM | None |
| Homo sapiens | Flap endonuclease 1 | Potency | 8912.5 | nM | None |
| Homo sapiens | Geminin | Potency | 5804.8 | nM | None |
| Homo sapiens | Geminin | Potency | 29092.9 | nM | None |
| Homo sapiens | Glucagon-like peptide 1 receptor | Potency | 12589.3 | nM | None |
| Homo sapiens | Glutaminase kidney isoform, mitochondrial | Potency | 3981.1 | nM | None |
| Homo sapiens | GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 | Potency | 56234.1 | nM | None |
| Homo sapiens | Guanine nucleotide-binding protein G(s), subunit alpha | Potency | 7079.5 | nM | None |
| Homo sapiens | HEK293 | Potency | 31622.8 | nM | None |
| Homo sapiens | Histone-lysine N-methyltransferase NSD2 | AC50 | 6490.0 | nM | None |
| Homo sapiens | Importin subunit beta-1/Snurportin-1 | Potency | 56234.1 | nM | None |
| Homo sapiens | Isocitrate dehydrogenase [NADP] cytoplasmic | Potency | 52119.4 | nM | None |
| Homo sapiens | Lysine-specific demethylase 4A | Potency | 44668.4 | nM | None |
| Homo sapiens | Nuclear factor erythroid 2-related factor 2 | Potency | 9200.0 | nM | None |
| Homo sapiens | Nuclear receptor ROR-gamma | IC50 | 80000.0 | nM | None |
| Homo sapiens | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Potency | 60119.8 | nM | None |
| Homo sapiens | Polyadenylate-binding protein 1 | IC50 | 66000.0 | nM | None |
| Homo sapiens | Protein-arginine N-methyltransferase 1 | IC50 | 928000.0 | nM | 10.1021/jm061213n |
| Homo sapiens | Protein-tyrosine phosphatase 2C | IC50 | 1040.0 | nM | None |
| Homo sapiens | Rap guanine nucleotide exchange factor 3 | Potency | 31622.8 | nM | None |
| Homo sapiens | Sphingomyelin phosphodiesterase | Potency | 31622.8 | nM | None |
| Homo sapiens | Transcriptional regulator ERG | Potency | 11220.2 | nM | None |
| Homo sapiens | Tyrosine-protein phosphatase non-receptor type 5 | IC50 | 33400.0 | nM | None |
| Homo sapiens | Ubiquitin carboxyl-terminal hydrolase 1 | Potency | 44668.4 | nM | None |
| Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)(HIV-1) | Human immunodeficiency virus type 1 Tat protein | IC50 | 47955.0 | nM | None |
| Rattus norvegicus | Thioredoxin reductase 1, cytoplasmic | Potency | 22387.2 | nM | None |
| Rattus norvegicus | Thioredoxin reductase 1, cytoplasmic | Potency | 79432.8 | nM | None |
| Trypanosoma brucei brucei | Phosphoglycerate kinase, glycosomal | Potency | 14125.4 | nM | None |
| None | Unchecked | IC50 | 9440.0 | nM | None |
| None | Unchecked | Potency | 11220.2 | nM | None |