N-acetyl-5-aminosalicylic acid
AlkaPlorer ID: AK042127
Synonym: None
IUPAC Name: 5-acetamido-2-hydroxybenzoic acid
Structure
SMILES: CC(=O)NC1=CC(C(=O)O)=C(O)C=C1
InChI: InChI=1S/C9H9NO4/c1-5(11)10-6-2-3-8(12)7(4-6)9(13)14/h2-4,12H,1H3,(H,10,11)(H,13,14)
InChIKey: GEFDRROBUCULOD-UHFFFAOYSA-N
Source
Properties Information
Molecule Weight: 195.174
TPSA？: 86.63000000000001
MolLogP？: 1.0487999999999995
Number of H-Donors: 3
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Krueppel-like factor 10 | Inhibition | nan | % | 10.1021/jm5018187 |
| Homo sapiens | Lysine-specific demethylase 4C | Inhibition | nan | % | 10.1021/acs.jmedchem.5b01527 |
| Rattus norvegicus | Rattus norvegicus | FC | 2.1 | None | 10.1016/j.bmcl.2015.04.023 |
| Rattus norvegicus | Rattus norvegicus | Inhibition | 0.0 | % | 10.1016/j.bmcl.2015.04.023 |
| Rattus norvegicus | Rattus norvegicus | Inhibition | 1.3 | % | 10.1016/j.bmcl.2015.04.023 |
| Rattus norvegicus | Rattus norvegicus | Inhibition | 7.9 | % | 10.1016/j.bmcl.2015.04.023 |
| Rattus norvegicus | Rattus norvegicus | Inhibition | 43.3 | % | 10.1016/j.bmcl.2015.04.023 |