Bracteoline
AlkaPlorer ID: AK042243
Synonym: '', 'Bracteoline'
IUPAC Name: (6aS)-2,9-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol
Structure
SMILES: COC1=CC2=C(C=C1O)C1=C(O)C(OC)=CC3=C1[C@H](C2)N(C)CC3
InChI: InChI=1S/C19H21NO4/c1-20-5-4-10-7-16(24-3)19(22)18-12-9-14(21)15(23-2)8-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1
InChIKey: PLEOQAHCVRVCDL-ZDUSSCGKSA-N
Reference
Chemical and Biological Extractives of Lauraceae Species in Costa Rican Tropical Forests
PubChem CID: 133322
CAS: 25651-04-1
LOTUS: LTS0112759
SuperNatural Ⅲ: SN0288394-02
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Corydalis gortschakovii | Corydalis | Papaveraceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 327.3800000000001
TPSA？: 62.16
MolLogP？: 2.867100000000001
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | 4'-phosphopantetheinyl transferase ffp | Potency | 50118.7 | nM | None |
| Giardia intestinalis | Putative fructose-1,6-bisphosphate aldolase | Potency | 9976.3 | nM | None |
| Homo sapiens | 15-hydroxyprostaglandin dehydrogenase [NAD+] | Potency | 31622.8 | nM | None |
| Homo sapiens | Aldehyde dehydrogenase 1A1 | Potency | 35481.3 | nM | None |
| Homo sapiens | Caspase-1 | Potency | 31622.8 | nM | None |
| Homo sapiens | Cellular tumor antigen p53 | Potency | 31622.8 | nM | None |
| Homo sapiens | Cytochrome P450 2C19 | Potency | 12589.3 | nM | None |
| Homo sapiens | Cytochrome P450 2C9 | Potency | 31622.8 | nM | None |
| Homo sapiens | Cytochrome P450 2D6 | Potency | 2511.9 | nM | None |
| Homo sapiens | Cytochrome P450 3A4 | Potency | 19952.6 | nM | None |
| Homo sapiens | DNA polymerase kappa | Potency | 1122.0 | nM | None |
| Homo sapiens | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Potency | 31622.8 | nM | None |
| Homo sapiens | Lysine-specific demethylase 4D-like | Potency | 35481.3 | nM | None |
| Homo sapiens | Microtubule-associated protein tau | Potency | 22387.2 | nM | None |
| Homo sapiens | Microtubule-associated protein tau | Potency | 28183.8 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 29855.4 | nM | None |
| Rattus norvegicus | Inositol monophosphatase 1 | Potency | 14125.4 | nM | None |
| Rattus norvegicus | Inositol monophosphatase 1 | Potency | 15848.9 | nM | None |
| None | Unchecked | Potency | 14125.4 | nM | None |