(+)-Oxoglaucine
AlkaPlorer ID: AK042420
Synonym: ''
IUPAC Name: (8S,21S)-16,27-dimethoxy-7,22-dimethyl-14,29,31-trioxa-7,22-diazaoctacyclo[19.9.3.210,13.14,30.115,19.03,8.025,33.028,32]heptatriaconta-1(30),2,4(34),10(37),11,13(36),15,17,19(35),25,27,32-dodecaene
Structure
SMILES: COC1=CC=C2C=C1OC1=CC=C(C=C1)C[C@H]1C3=C(C=C4OC5=C(OC)C=C6CCN(C)[C@@H](C2)C6=C5OC4=C3)CCN1C
InChI: InChI=1S/C36H36N2O5/c1-37-13-11-23-18-31-32-20-26(23)27(37)15-21-5-8-25(9-6-21)41-30-17-22(7-10-29(30)39-3)16-28-34-24(12-14-38(28)2)19-33(40-4)35(42-31)36(34)43-32/h5-10,17-20,27-28H,11-16H2,1-4H3/t27-,28-/m0/s1
InChIKey: ZBDGREIBILVVBE-NSOVKSMOSA-N
Reference
Alkaloids from<i>Chasmanthera dependens</i>
PubChem CID: 10769503
LOTUS: LTS0238650
SuperNatural Ⅲ: SN0465697-01
NPASS: NPC129518
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Pachygone dasycarpa | Pachygone | Menispermaceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 576.6930000000002
TPSA？: 52.63
MolLogP？: 7.250900000000007
Number of H-Donors: 0
Number of H-Acceptors: 7
RingCount: 9
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | KB | IC50 | 5.9 | ug.mL-1 | 10.1021/np960568e |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 0.204 | ug.mL-1 | 10.1021/np960568e |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 0.326 | ug.mL-1 | 10.1021/np960568e |